Modern treatment of haemophilia.

PubWeight™: 1.35‹?› | Rank: Top 10%

🔗 View Article (PMC 2486807)

Published in Bull World Health Organ on January 01, 1995

Authors

E Berntorp1, V Boulyjenkov, D Brettler, M Chandy, P Jones, C Lee, J Lusher, P Mannucci, I Peak, K Rickard

Author Affiliations

1: Department of Coagulation Disorders, Allmanna Sjukhuset, Malmo, Sweden.

Associated clinical trials:

Evaluate Efficacy and Safety of ADVATE in the Standard Prophylaxis Treatment of Severe or Moderately Severe Hemophilia A | NCT02282410

Efficacy and Safety of ADVATE Standard Prophylaxis to Hemophilia A | NCT02280265

Articles citing this

Principles of treatment and update of recommendations for the management of haemophilia and congenital bleeding disorders in Italy. Blood Transfus (2014) 1.46

Treatment of hemophilia: a review of current advances and ongoing issues. J Blood Med (2010) 1.07

Intermediate-dose versus high-dose prophylaxis for severe hemophilia: comparing outcome and costs since the 1970s. Blood (2013) 1.02

Primary prophylaxis in children with haemophilia. Blood Transfus (2008) 0.94

Secondary prophylaxis in adolescent and adult haemophiliacs. Blood Transfus (2008) 0.87

Intravascular recovery of VWF and FVIII following intraperitoneal injection and differences from intravenous and subcutaneous injection in mice. Haemophilia (2012) 0.87

Randomized comparison of prophylaxis and on-demand regimens with FEIBA NF in the treatment of haemophilia A and B with inhibitors. Haemophilia (2013) 0.86

Antihemophilic factor (recombinant) plasma/albumin-free method for the management and prevention of bleeding episodes in patients with hemophilia A. Biologics (2009) 0.86

Assessment of the impact of treatment on quality of life of patients with haemophilia A at different ages: insights from two clinical trials on turoctocog alfa. Haemophilia (2014) 0.82

The effect of secondary prophylaxis versus episodic treatment on the range of motion of target joints in patients with haemophilia. Br J Haematol (2013) 0.79

Review of antihemophilic factor injection for the routine prophylaxis of bleeding episodes and risk of joint damage in severe hemophilia A. Vasc Health Risk Manag (2010) 0.78

The influence of prophylactic factor VIII in severe haemophilia A. Haemophilia (2011) 0.78

Current and evolving features in the clinical management of haemophilia. Blood Transfus (2014) 0.78

Need for Prophylactic Treatment in Adult Haemophilia A Patients. Transfus Med Hemother (2009) 0.77

Barriers to primary prophylaxis in haemophilic children: the issue of the venous access. Blood Transfus (2008) 0.77

Prevalence, incidence, and factor concentrate usage trends of hemophiliacs in Taiwan. Yonsei Med J (2013) 0.76

Haemophilia at various stages of life: design of new therapeutic strategies through an interactive course--the Kogeniale project. Blood Transfus (2013) 0.75

Aspects of prophylactic treatment of hemophilia. Thromb J (2016) 0.75

Practice of Iranian Adolescents with Hemophilia in Prevention of Complications of Hemophilia. Indian J Palliat Care (2015) 0.75

Management of hemophilia in Korea: the past, present, and future. Blood Res (2014) 0.75

Target of prophylaxis in severe haemophilia: more than factor levels. Blood Transfus (2012) 0.75

Humanistic and economic aspects of haemophilia treatment in Bulgaria. Comparison between two therapeutic approaches: prophylactic vs. on-demand treatment. Biotechnol Biotechnol Equip (2014) 0.75

Nonsense-mediated mRNA decay among coagulation factor genes. Iran J Basic Med Sci (2016) 0.75

Turoctocog alfa: an evidence-based review of its potential in the treatment of hemophilia A. Drug Des Devel Ther (2015) 0.75

Social/economic costs and quality of life in patients with haemophilia in Europe. Eur J Health Econ (2016) 0.75

Articles cited by this

Incidence of development of factor VIII and factor IX inhibitors in haemophiliacs. Lancet (1992) 5.59

B19 parvovirus DNA in solvent/detergent-treated anti-haemophilia concentrates. Lancet (1994) 3.31

Twenty-five years' experience of prophylactic treatment in severe haemophilia A and B. J Intern Med (1992) 3.21

Three-year randomised study of high-purity or intermediate-purity factor VIII concentrates in symptom-free HIV-seropositive haemophiliacs: effects on immune status. Lancet (1993) 3.03

A higher than expected incidence of factor VIII inhibitors in multitransfused haemophilia A patients treated with an intermediate purity pasteurized factor VIII concentrate. Thromb Haemost (1993) 1.56

Clinical evaluation of viral safety of coagulation factor VIII and IX concentrates. Vox Sang (1993) 1.54

Parvovirus B19 and blood products. Lancet (1994) 1.44

A multicenter study of viral hepatitis in a United States hemophilic population. Blood (1993) 1.37

Use of several second generation serological assays to determine the true prevalence of hepatitis C virus infection in haemophiliacs treated with non-virus inactivated factor VIII and IX concentrates. Br J Haematol (1992) 1.02

Acute hepatitis A in patients with haemophilia A. Lancet (1993) 0.99

Pharmacokinetic dosing in prophylactic treatment of hemophilia A. Eur J Haematol (1993) 0.94

The use of porcine factor VIII concentrate (Hyate:C) in the treatment of patients with inhibitor antibodies to factor VIII. A multicenter US experience. Arch Intern Med (1989) 0.94

Transmission of human parvovirus B19 by coagulation factor concentrates. Vox Sang (1990) 0.94

Adjusted dose continuous infusion of factor VIII in patients with haemophilia A. Br J Haematol (1992) 0.87

Recent evolution of clotting factor concentrates for hemophilia A and B. Transfusion Practices Committee. Transfusion (1993) 0.84

Viral contamination of blood products. Lancet (1994) 0.81

Hemophilic patients with an inhibitor to factor VIII treated with high dose factor VIII concentrate. Results of a collaborative study for the evaluation of factor VIII inhibitor titer, recovery and half life of infused factor VIII. Nouv Rev Fr Hematol (1986) 0.81

Induction of immune tolerance in hemophiliacs with inhibitors by combined treatment with i.v. IgG, cyclophosphamide and factor VIII or IX. Prog Clin Biol Res (1990) 0.80

Articles by these authors

TOTAL ACID-BASE EQUILIBRIUM OF PLASMA IN HEALTH AND DISEASE: VII. Factors Causing Acidosis in Chronic Nephritis. A Preliminary Report. J Clin Invest (1926) 14.83

Genetic organization and diversity of the hepatitis C virus. Proc Natl Acad Sci U S A (1991) 14.05

TOTAL ACID-BASE EQUILIBRIUM OF PLASMA IN HEALTH AND DISEASE: X. The Acidosis of Nephritis. J Clin Invest (1929) 10.24

TOTAL ACID-BASE EQUILIBRIUM OF PLASMA IN HEALTH AND DISEASE: VI. Studies of Diabetes. J Clin Invest (1925) 9.92

Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation. Cell (1999) 9.84

Boron nitride substrates for high-quality graphene electronics. Nat Nanotechnol (2010) 9.72

Detection of hepatitis C viral sequences in non-A, non-B hepatitis. Lancet (1990) 8.56

Genome-wide detection of alternative splicing in expressed sequences of human genes. Nucleic Acids Res (2001) 7.27

TOTAL ACID-BASE EQUILIBRIUM OF PLASMA IN HEALTH AND DISEASE: XII. A Study of Renal Edema. J Clin Invest (1929) 6.48

TMPRSS2:ERG gene fusion associated with lethal prostate cancer in a watchful waiting cohort. Oncogene (2007) 5.79

The autism genetic resource exchange: a resource for the study of autism and related neuropsychiatric conditions. Am J Hum Genet (2001) 5.23

The tyrosine-86 allele of the pfmdr1 gene of Plasmodium falciparum is associated with increased sensitivity to the anti-malarials mefloquine and artemisinin. Mol Biochem Parasitol (2000) 4.08

Prevalence of Kaposi's sarcoma associated herpesvirus infection measured by antibodies to recombinant capsid protein and latent immunofluorescence antigen. Lancet (1996) 4.05

Prediction of colorectal cancer by a patient consultation questionnaire and scoring system: a prospective study. Lancet (2002) 3.95

Fragile X premutation is a significant risk factor for premature ovarian failure: the International Collaborative POF in Fragile X study--preliminary data. Am J Med Genet (1999) 3.82

Identification of p53 gene mutations in bladder cancers and urine samples. Science (1991) 3.68

Unraveling the hidden catalytic activity of vertebrate class IIa histone deacetylases. Proc Natl Acad Sci U S A (2007) 3.60

Frequency of inhibitor development in haemophiliacs treated with low-purity factor VIII. Lancet (1993) 3.58

Leptin differentially regulates NPY and POMC neurons projecting to the lateral hypothalamic area. Neuron (1999) 3.37

Expression, identification and subcellular localization of the proteins encoded by the hepatitis C viral genome. J Gen Virol (1993) 3.18

The preterm prediction study: maternal stress is associated with spontaneous preterm birth at less than thirty-five weeks' gestation. National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network. Am J Obstet Gynecol (1996) 3.09

Three-year randomised study of high-purity or intermediate-purity factor VIII concentrates in symptom-free HIV-seropositive haemophiliacs: effects on immune status. Lancet (1993) 3.03

Chemically defined projections linking the mediobasal hypothalamus and the lateral hypothalamic area. J Comp Neurol (1998) 3.01

Heatstroke in well-wrapped infants. Lancet (1979) 2.81

Abeta vaccination effects on plaque pathology in the absence of encephalitis in Alzheimer disease. Neurology (2005) 2.79

Criteria for diagnosing Parkinson's disease. Ann Neurol (1992) 2.78

Does prediction of outcome alter patient management? Lancet (1993) 2.75

Targeted disruption of the mPer3 gene: subtle effects on circadian clock function. Mol Cell Biol (2000) 2.69

The hepatitis C virus encodes a serine protease involved in processing of the putative nonstructural proteins from the viral polyprotein precursor. Biochem Biophys Res Commun (1993) 2.67

TOTAL ACID-BASE EQUILIBRIUM OF PLASMA IN HEALTH AND DISEASE: XI. Hypochloremia and Total Salt Deficiency in Nephritis. J Clin Invest (1929) 2.64

Validation of the Edinburgh Postnatal Depression Scale (EPDS) in non-postnatal women. J Affect Disord (1996) 2.62

Stimulation of human epidermal differentiation by delta-notch signalling at the boundaries of stem-cell clusters. Curr Biol (2000) 2.58

Characterization of the hepatitis C virus E2/NS1 gene product expressed in mammalian cells. Virology (1992) 2.58

AIDS and haemophilia: morbidity and morality in a well defined population. Br Med J (Clin Res Ed) (1985) 2.54

Anterior paralimbic mediation of procaine-induced emotional and psychosensory experiences. Arch Gen Psychiatry (1996) 2.53

Amplification of EGFR T790M causes resistance to an irreversible EGFR inhibitor. Oncogene (2010) 2.53

Fluticasone propionate/salmeterol combination provides more effective asthma control than low-dose inhaled corticosteroid plus montelukast. J Allergy Clin Immunol (2000) 2.51

Transcriptional induction of the PML growth suppressor gene by interferons is mediated through an ISRE and a GAS element. Oncogene (1995) 2.50

Mutations in the novel protocadherin PCDH15 cause Usher syndrome type 1F. Hum Mol Genet (2001) 2.48

Leptin activates hypothalamic CART neurons projecting to the spinal cord. Neuron (1998) 2.46

A global survey of haplotype frequencies and linkage disequilibrium at the DRD2 locus. Hum Genet (1998) 2.44

Developing and deploying a patient safety program in a large health care delivery system: you can't fix what you don't know about. Jt Comm J Qual Improv (2001) 2.42

Validity of the Migraine Disability Assessment (MIDAS) score in comparison to a diary-based measure in a population sample of migraine sufferers. Pain (2000) 2.41

Cloning and characterization of an ftsZ homologue from a bacterial symbiont of Drosophila melanogaster. Mol Gen Genet (1993) 2.40

Detection of major histocompatibility complex class I-restricted, HIV-specific cytotoxic T lymphocytes in the blood of infected hemophiliacs. Blood (1989) 2.37

Glycosyltransferases in plant natural product synthesis: characterization of a supergene family. Trends Plant Sci (2000) 2.37

The prevalence of lower urinary tract symptoms in men and women in four centres. The UrEpik study. BJU Int (2003) 2.32

Genetic disruption of Ptgs-1, as well as Ptgs-2, reduces intestinal tumorigenesis in Min mice. Cancer Res (2000) 2.28

Premorbid social functioning in schizophrenia and bipolar disorder: similarities and differences. Am J Psychiatry (1997) 2.26

Srg3, a mouse homolog of yeast SWI3, is essential for early embryogenesis and involved in brain development. Mol Cell Biol (2001) 2.26

Efficacy of progesterone and progestogens in management of premenstrual syndrome: systematic review. BMJ (2001) 2.23

Psychosis with good prognosis in Afro-Caribbean people now living in the United Kingdom. BMJ (1995) 2.22

Diagnosis of hepatitis C virus (HCV) infection using an immunodominant chimeric polyprotein to capture circulating antibodies: reevaluation of the role of HCV in liver disease. Proc Natl Acad Sci U S A (1992) 2.18

Aggregation of ferrihaems. Dimerization and protolytic equilibria of protoferrihaem and deuteroferrihaem in aqueous solution. Biochem J (1970) 2.16

Women's Health Australia: recruitment for a national longitudinal cohort study. Women Health (1998) 2.16

A quantitative assessment of residual protein levels on dental instruments reprocessed by manual, ultrasonic and automated cleaning methods. Br Dent J (2011) 2.13

Chemotactic properties of angiopoietin-1 and -2, ligands for the endothelial-specific receptor tyrosine kinase Tie2. J Biol Chem (1998) 2.12

Evidence-based recommendations for the use of Negative Pressure Wound Therapy in traumatic wounds and reconstructive surgery: steps towards an international consensus. Injury (2011) 2.07

Analgesia nociception index: evaluation as a new parameter for acute postoperative pain. Br J Anaesth (2013) 2.04

Effect of tiotropium on sputum and serum inflammatory markers and exacerbations in COPD. Eur Respir J (2007) 2.03

Psychopathological syndromes and familial morbid risk of psychosis. Br J Psychiatry (1997) 2.02

Neoadjuvant chemoradiation for localized adenocarcinoma of the pancreas. Ann Surg Oncol (2001) 2.01

Salmeterol plus theophylline combination therapy in the treatment of COPD. Chest (2001) 2.01

Inherited thrombophilia: Part 1. Thromb Haemost (1996) 2.00

School performance in Finnish children and later development of schizophrenia: a population-based longitudinal study. Arch Gen Psychiatry (1999) 1.97

Effect of endotoxin on granulopoiesis and colony-stimulating factor. N Engl J Med (1972) 1.96

Unusual association of Kikuchi's disease and dengue virus infection evolving into systemic lupus erythematosus. J Indian Med Assoc (2000) 1.96

Circadian regulation of a Drosophila homolog of the mammalian Clock gene: PER and TIM function as positive regulators. Mol Cell Biol (1998) 1.96

Infrared evidence for an oxo-bridged (Fe-O-Fe) haemin dimer. Nature (1969) 1.95

Evidence for a Wolbachia symbiont in Drosophila melanogaster. Genet Res (1993) 1.95

The sequence of chick alpha-actinin reveals homologies to spectrin and calmodulin. J Biol Chem (1987) 1.95

Interleukin-6 as a paracrine and autocrine growth factor in human prostatic carcinoma cells in vitro. Cancer Res (1997) 1.95

The catalase-hydrogen peroxide system. A theoretical appraisal of the mechanism of catalase action. Biochem J (1968) 1.94

Hyperuricemia and urate nephropathy in urate oxidase-deficient mice. Proc Natl Acad Sci U S A (1994) 1.88

The impact of nocturnal symptoms associated with gastroesophageal reflux disease on health-related quality of life. Arch Intern Med (2001) 1.88

Difficult extubation due to transfixation of a nasotracheal tube by a Kirschner wire. Anesthesiology (1977) 1.88

Why do outpatients fail to keep their clinic appointments? Results from a survey and recommended remedial actions. Int J Clin Pract (1998) 1.87

Randomized clinical trial of the effects of preoperative and postoperative oral nutritional supplements on clinical course and cost of care. Br J Surg (2004) 1.84

Strategies for preventing suicide. Br J Psychiatry (1997) 1.83

Identification of mammalian noggin and its expression in the adult nervous system. J Neurosci (1995) 1.81

Does cost information availability reduce physician test usage? A randomized clinical trial with unexpected findings. Med Care (1982) 1.80

Can excellent school performance be a precursor of schizophrenia? A 28-year follow-up in the Northern Finland 1966 birth cohort. Acta Psychiatr Scand (1999) 1.78

The founder mutation MSH2*1906G-->C is an important cause of hereditary nonpolyposis colorectal cancer in the Ashkenazi Jewish population. Am J Hum Genet (2002) 1.77

Evaluation of laboratory methods for detecting acute TRIC agent infection. Am J Ophthalmol (1970) 1.77

HHV-6 in AIDS. Lancet (1994) 1.76

Screening for hepatocellular carcinoma in chronic carriers of hepatitis B virus: incidence and prevalence of hepatocellular carcinoma in a North American urban population. Hepatology (1995) 1.76

Treatment of children with newly diagnosed acute promyelocytic leukemia with arsenic trioxide: a single center experience. Leukemia (2004) 1.76

Effects of pulsed ultrasound on the mouse neonate: hind limb paralysis and lung hemorrhage. Ultrasound Med Biol (1994) 1.74

dCLOCK is present in limiting amounts and likely mediates daily interactions between the dCLOCK-CYC transcription factor and the PER-TIM complex. J Neurosci (2000) 1.73

Preoperative chemoradiation for patients with locally advanced adenocarcinoma of the pancreas. Ann Surg Oncol (1999) 1.73

Thymus-independent development and negative selection of T cells expressing T cell receptor alpha/beta in the intestinal epithelium: evidence for distinct circulation patterns of gut- and thymus-derived T lymphocytes. J Exp Med (1992) 1.73

Ribavirin treatment for patients with chronic hepatitis C: results of a placebo-controlled study. J Hepatol (1996) 1.73

A randomized controlled trial of artemether/benflumetol, a new antimalarial and pyrimethamine/sulfadoxine in the treatment of uncomplicated falciparum malaria in African children. Am J Trop Med Hyg (1998) 1.72

The "second gas effect" is not a valid concept. Anesth Analg (1999) 1.72

Necrotizing fasciitis of perineum. Surgery (1982) 1.72

Development of a database of organ doses for paediatric and young adult CT scans in the United Kingdom. Radiat Prot Dosimetry (2012) 1.71

Developmental precursors of affective illness in a general population birth cohort. Arch Gen Psychiatry (1997) 1.70

Use of a long-acting inhaled beta2-adrenergic agonist, salmeterol xinafoate, in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2001) 1.70