Published in Science on December 06, 1996
Low Dose Melphalan and Bortezomib for AML and High-Risk MDS | NCT00789256
Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization. Genes Dev (1998) 12.55
Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2. J Cell Biol (2001) 6.80
Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability. Genes Dev (2000) 6.54
Selective small-molecule inhibitor reveals critical mitotic functions of human CDK1. Proc Natl Acad Sci U S A (2006) 5.16
The regulatory particle of the Saccharomyces cerevisiae proteasome. Mol Cell Biol (1998) 4.63
BTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the Cullin 3-Roc1 ligase. Mol Cell Biol (2005) 4.53
Visualization of Mad2 dynamics at kinetochores, along spindle fibers, and at spindle poles in living cells. J Cell Biol (2000) 4.26
Herpes simplex virus 1 alpha regulatory protein ICP0 interacts with and stabilizes the cell cycle regulator cyclin D3. J Virol (1997) 4.26
Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34. Genes Dev (1999) 4.17
Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27. EMBO J (1997) 4.17
Human BUBR1 is a mitotic checkpoint kinase that monitors CENP-E functions at kinetochores and binds the cyclosome/APC. J Cell Biol (1999) 4.15
HuR regulates cyclin A and cyclin B1 mRNA stability during cell proliferation. EMBO J (2000) 4.11
Modification of yeast Cdc53p by the ubiquitin-related protein rub1p affects function of the SCFCdc4 complex. Genes Dev (1998) 3.84
Kinetic analysis of a molecular model of the budding yeast cell cycle. Mol Biol Cell (2000) 3.63
The Schizosaccharomyces pombe spindle checkpoint protein mad2p blocks anaphase and genetically interacts with the anaphase-promoting complex. Proc Natl Acad Sci U S A (1997) 3.53
MAD2 associates with the cyclosome/anaphase-promoting complex and inhibits its activity. Proc Natl Acad Sci U S A (1997) 3.42
The Cdc4/34/53 pathway targets Cdc6p for proteolysis in budding yeast. EMBO J (1997) 3.35
Dynamic association of proteasomal machinery with the centrosome. J Cell Biol (1999) 3.30
Human CUL-1 associates with the SKP1/SKP2 complex and regulates p21(CIP1/WAF1) and cyclin D proteins. Proc Natl Acad Sci U S A (1998) 3.26
A late mitotic regulatory network controlling cyclin destruction in Saccharomyces cerevisiae. Mol Biol Cell (1998) 3.18
Cyclin A is destroyed in prometaphase and can delay chromosome alignment and anaphase. J Cell Biol (2001) 3.18
An essential protease involved in bacterial cell-cycle control. EMBO J (1998) 3.07
The highly conserved Ndc80 complex is required for kinetochore assembly, chromosome congression, and spindle checkpoint activity. Genes Dev (2003) 3.04
Fizzy is required for activation of the APC/cyclosome in Xenopus egg extracts. EMBO J (1998) 3.02
Grr1 of Saccharomyces cerevisiae is connected to the ubiquitin proteolysis machinery through Skp1: coupling glucose sensing to gene expression and the cell cycle. EMBO J (1997) 2.97
Stem-loop binding protein, the protein that binds the 3' end of histone mRNA, is cell cycle regulated by both translational and posttranslational mechanisms. Mol Cell Biol (2000) 2.90
Phosphorylation- and ubiquitin-dependent degradation of the cyclin-dependent kinase inhibitor Far1p in budding yeast. Genes Dev (1997) 2.77
DDB1 functions as a linker to recruit receptor WD40 proteins to CUL4-ROC1 ubiquitin ligases. Genes Dev (2006) 2.75
SEL-10 is an inhibitor of notch signaling that targets notch for ubiquitin-mediated protein degradation. Mol Cell Biol (2001) 2.56
Yeast Hct1 recognizes the mitotic cyclin Clb2 and other substrates of the ubiquitin ligase APC. EMBO J (2001) 2.55
The polo-like kinase Plx1 is required for M phase exit and destruction of mitotic regulators in Xenopus egg extracts. EMBO J (1998) 2.48
Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. Mol Cell Proteomics (2010) 2.43
The disappearance of cyclin B at the end of mitosis is regulated spatially in Drosophila cells. EMBO J (1999) 2.34
Degradation signals for ubiquitin system proteolysis in Saccharomyces cerevisiae. EMBO J (1998) 2.34
Nuclear localization of cyclin B1 controls mitotic entry after DNA damage. J Cell Biol (1998) 2.33
ClpX(P) generates mechanical force to unfold and translocate its protein substrates. Cell (2011) 2.31
Proteasome inhibitors: an expanding army attacking a unique target. Chem Biol (2012) 2.26
Mitosis in vertebrate somatic cells with two spindles: implications for the metaphase/anaphase transition checkpoint and cleavage. Proc Natl Acad Sci U S A (1997) 2.23
Targeting proteins for degradation. Nat Chem Biol (2009) 2.22
D box and KEN box motifs in budding yeast Hsl1p are required for APC-mediated degradation and direct binding to Cdc20p and Cdh1p. Genes Dev (2001) 2.20
The ubiquitin-proteasome pathway and proteasome inhibitors. Med Res Rev (2001) 2.18
sel-10, a negative regulator of lin-12 activity in Caenorhabditis elegans, encodes a member of the CDC4 family of proteins. Genes Dev (1997) 2.17
The degradation of promyelocytic leukemia and Sp100 proteins by herpes simplex virus 1 is mediated by the ubiquitin-conjugating enzyme UbcH5a. Proc Natl Acad Sci U S A (2003) 2.12
Exit from mitosis in Drosophila syncytial embryos requires proteolysis and cyclin degradation, and is associated with localized dephosphorylation. Genes Dev (1998) 2.09
The CUL1 C-terminal sequence and ROC1 are required for efficient nuclear accumulation, NEDD8 modification, and ubiquitin ligase activity of CUL1. Mol Cell Biol (2000) 2.09
Proteasome inhibitors block development of Plasmodium spp. Antimicrob Agents Chemother (1998) 2.07
The ClpXP protease unfolds substrates using a constant rate of pulling but different gears. Cell (2013) 2.06
Fission yeast bub1 is a mitotic centromere protein essential for the spindle checkpoint and the preservation of correct ploidy through mitosis. J Cell Biol (1998) 2.05
Differential mRNA translation and meiotic progression require Cdc2-mediated CPEB destruction. EMBO J (2002) 2.04
Rad53-dependent phosphorylation of Swi6 and down-regulation of CLN1 and CLN2 transcription occur in response to DNA damage in Saccharomyces cerevisiae. Genes Dev (1997) 2.01
MOB1, an essential yeast gene required for completion of mitosis and maintenance of ploidy. Mol Biol Cell (1998) 2.00
Control of Swe1p degradation by the morphogenesis checkpoint. EMBO J (1998) 1.99
The ATM-p53 pathway suppresses aneuploidy-induced tumorigenesis. Proc Natl Acad Sci U S A (2010) 1.98
Alternative splicing results in differential expression, activity, and localization of the two forms of arginyl-tRNA-protein transferase, a component of the N-end rule pathway. Mol Cell Biol (1999) 1.96
smg-7 is required for mRNA surveillance in Caenorhabditis elegans. Genetics (1999) 1.90
Efficient targeted gene disruption in the soma and germ line of the frog Xenopus tropicalis using engineered zinc-finger nucleases. Proc Natl Acad Sci U S A (2011) 1.90
Entry into mitosis in vertebrate somatic cells is guarded by a chromosome damage checkpoint that reverses the cell cycle when triggered during early but not late prophase. J Cell Biol (1998) 1.89
Activation of Cdh1-dependent APC is required for G1 cell cycle arrest and DNA damage-induced G2 checkpoint in vertebrate cells. EMBO J (2001) 1.88
Cell cycle -dependent proteolysis in plants. Identification Of the destruction box pathway and metaphase arrest produced by the proteasome inhibitor mg132 Plant Cell (1998) 1.88
The paramyxovirus simian virus 5 V protein slows progression of the cell cycle. J Virol (2000) 1.85
Fission yeast ch-TOG/XMAP215 homologue Alp14 connects mitotic spindles with the kinetochore and is a component of the Mad2-dependent spindle checkpoint. EMBO J (2001) 1.83
Evidence that HetR protein is an unusual serine-type protease. Proc Natl Acad Sci U S A (1998) 1.83
Drosophila Cyclin B3 is required for female fertility and is dispensable for mitosis like Cyclin B. Genes Dev (1998) 1.82
Ligand-induced cleavage and regulation of nuclear entry of Notch in Drosophila melanogaster embryos. Genes Dev (1998) 1.82
The Drosophila Geminin homolog: roles for Geminin in limiting DNA replication, in anaphase and in neurogenesis. Genes Dev (2001) 1.81
The regulatory crosstalk between kinases and proteases in cancer. Nat Rev Cancer (2010) 1.80
Inhibition of NF-kappa-B cellular function via specific targeting of the I-kappa-B-ubiquitin ligase. EMBO J (1997) 1.78
Why Do Plant Cells Divide? Plant Cell (1997) 1.77
Growth rate-dependent regulation of medial FtsZ ring formation. J Bacteriol (2003) 1.77
Characterization of Arabidopsis and rice DWD proteins and their roles as substrate receptors for CUL4-RING E3 ubiquitin ligases. Plant Cell (2008) 1.77
Retracted Regulation of APC activity by phosphorylation and regulatory factors. J Cell Biol (1999) 1.76
Bub1p kinase activates the Saccharomyces cerevisiae spindle assembly checkpoint. Mol Cell Biol (1998) 1.75
The human kinesin-like protein RB6K is under tight cell cycle control and is essential for cytokinesis. Mol Cell Biol (2001) 1.75
Nonperiodic activity of the human anaphase-promoting complex-Cdh1 ubiquitin ligase results in continuous DNA synthesis uncoupled from mitosis. Mol Cell Biol (2000) 1.74
Mad2 and BubR1 function in a single checkpoint pathway that responds to a loss of tension. Mol Biol Cell (2002) 1.72
The N-end rule pathway controls the import of peptides through degradation of a transcriptional repressor. EMBO J (1998) 1.71
The checkpoint protein Chfr is a ligase that ubiquitinates Plk1 and inhibits Cdc2 at the G2 to M transition. J Cell Biol (2002) 1.69
Role of the proteasome and NF-kappaB in streptococcal cell wall-induced polyarthritis. Proc Natl Acad Sci U S A (1998) 1.69
Mitotic progression becomes irreversible in prometaphase and collapses when Wee1 and Cdc25 are inhibited. Mol Biol Cell (2011) 1.68
A giant ubiquitin-conjugating enzyme related to IAP apoptosis inhibitors. J Cell Biol (1998) 1.68
BubR1 acetylation at prometaphase is required for modulating APC/C activity and timing of mitosis. EMBO J (2009) 1.66
Sgt1p contributes to cyclic AMP pathway activity and physically interacts with the adenylyl cyclase Cyr1p/Cdc35p in budding yeast. Eukaryot Cell (2002) 1.66
Subunit-specific degradation of the UmuD/D' heterodimer by the ClpXP protease: the role of trans recognition in UmuD' stability. EMBO J (2000) 1.64
Localization of the 26S proteasome during mitosis and meiosis in fission yeast. EMBO J (1998) 1.61
Control of Saccharomyces cerevisiae filamentous growth by cyclin-dependent kinase Cdc28. Mol Cell Biol (1999) 1.61
APC2 Cullin protein and APC11 RING protein comprise the minimal ubiquitin ligase module of the anaphase-promoting complex. Mol Biol Cell (2001) 1.59
DNA damage-induced mitotic catastrophe is mediated by the Chk1-dependent mitotic exit DNA damage checkpoint. Proc Natl Acad Sci U S A (2005) 1.57
Cell-free degradation of p27(kip1), a G1 cyclin-dependent kinase inhibitor, is dependent on CDK2 activity and the proteasome. Mol Cell Biol (1999) 1.57
Genome-wide analysis of the cyclin family in Arabidopsis and comparative phylogenetic analysis of plant cyclin-like proteins. Plant Physiol (2004) 1.56
The ubiquitin-proteasome pathway in cancer. Br J Cancer (1998) 1.56
The Cdc42p effector Gic2p is targeted for ubiquitin-dependent degradation by the SCFGrr1 complex. EMBO J (1998) 1.50
Caspase-dependent activation of cyclin-dependent kinases during Fas-induced apoptosis in Jurkat cells. Proc Natl Acad Sci U S A (1998) 1.49
Xe-p9, a Xenopus Suc1/Cks protein, is essential for the Cdc2-dependent phosphorylation of the anaphase- promoting complex at mitosis. Genes Dev (1998) 1.48
p21CIP1 and Cdc25A: competition between an inhibitor and an activator of cyclin-dependent kinases. Mol Cell Biol (1997) 1.46
Cell cycle-dependent degradation of the Saccharomyces cerevisiae spindle motor Cin8p requires APC(Cdh1) and a bipartite destruction sequence. Mol Biol Cell (2001) 1.46
Protein synthesis rate is the predominant regulator of protein expression during differentiation. Mol Syst Biol (2013) 1.46
The COOH-terminal domain of wild-type Cot regulates its stability and kinase specific activity. Mol Cell Biol (2003) 1.45
A novel ubiquitin-specific protease, UBP43, cloned from leukemia fusion protein AML1-ETO-expressing mice, functions in hematopoietic cell differentiation. Mol Cell Biol (1999) 1.44
A MHC-encoded ubiquitin-like protein (FAT10) binds noncovalently to the spindle assembly checkpoint protein MAD2. Proc Natl Acad Sci U S A (1999) 1.44
Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis. J Biol Chem (1977) 72.51
Cyclin is degraded by the ubiquitin pathway. Nature (1991) 17.93
Number and evolutionary conservation of alpha- and beta-tubulin and cytoplasmic beta- and gamma-actin genes using specific cloned cDNA probes. Cell (1980) 17.55
A protein factor essential for microtubule assembly. Proc Natl Acad Sci U S A (1975) 15.35
Cyclin synthesis drives the early embryonic cell cycle. Nature (1989) 9.73
A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p. Cell (1997) 8.97
The role of cyclin synthesis and degradation in the control of maturation promoting factor activity. Nature (1989) 8.69
A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B. Cell (1995) 8.34
Anaphase initiation in Saccharomyces cerevisiae is controlled by the APC-dependent degradation of the anaphase inhibitor Pds1p. Genes Dev (1996) 8.28
The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assembly. Cell (1999) 8.07
Peroxisome proliferator-activated receptor alpha mediates the adaptive response to fasting. J Clin Invest (1999) 6.99
Cyclin activation of p34cdc2. Cell (1990) 6.87
Geminin, an inhibitor of DNA replication, is degraded during mitosis. Cell (1998) 6.69
The KEN box: an APC recognition signal distinct from the D box targeted by Cdh1. Genes Dev (2000) 6.43
cdc25 is a specific tyrosine phosphatase that directly activates p34cdc2. Cell (1991) 6.32
Identification of a vertebrate sister-chromatid separation inhibitor involved in transformation and tumorigenesis. Science (1999) 6.07
Exit from mitosis is triggered by Tem1-dependent release of the protein phosphatase Cdc14 from nucleolar RENT complex. Cell (1999) 5.98
The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation. Genes Dev (1998) 5.96
Bioenergetics and kinetics of microtubule and actin filament assembly-disassembly. Int Rev Cytol (1982) 5.93
Homologies in both primary and secondary structure between nuclear envelope and intermediate filament proteins. Nature (1986) 5.90
Dominoes and clocks: the union of two views of the cell cycle. Science (1989) 5.74
Nucleotide and corresponding amino acid sequences encoded by alpha and beta tubulin mRNAs. Nature (1981) 5.65
Filament organization revealed in platinum replicas of freeze-dried cytoskeletons. J Cell Biol (1980) 5.61
Sequence-specific and phosphorylation-dependent proline isomerization: a potential mitotic regulatory mechanism. Science (1997) 5.40
Direct binding of CDC20 protein family members activates the anaphase-promoting complex in mitosis and G1. Mol Cell (1998) 5.28
Proteasomal proteomics: identification of nucleotide-sensitive proteasome-interacting proteins by mass spectrometric analysis of affinity-purified proteasomes. Mol Biol Cell (2000) 5.19
The PPARalpha-leukotriene B4 pathway to inflammation control. Nature (1996) 5.14
Modulation of the dynamic instability of tubulin assembly by the microtubule-associated protein tau. Mol Biol Cell (1992) 5.11
Two distinct pathways remove mammalian cohesin from chromosome arms in prophase and from centromeres in anaphase. Cell (2000) 5.10
Mitosis in transition. Cell (1994) 5.03
Polewards chromosome movement driven by microtubule depolymerization in vitro. Nature (1988) 4.97
A yeast mutant defective at an early stage in import of secretory protein precursors into the endoplasmic reticulum. J Cell Biol (1987) 4.94
Negative regulation of Gcn4 and Msn2 transcription factors by Srb10 cyclin-dependent kinase. Genes Dev (2001) 4.91
Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome. Science (2001) 4.82
Physical and chemical properties of purified tau factor and the role of tau in microtubule assembly. J Mol Biol (1977) 4.60
Purification of tau, a microtubule-associated protein that induces assembly of microtubules from purified tubulin. J Mol Biol (1977) 4.42
Implications of treadmilling for the stability and polarity of actin and tubulin polymers in vivo. J Cell Biol (1980) 4.39
Ubiquitination by the anaphase-promoting complex drives spindle checkpoint inactivation. Nature (2007) 4.31
Expression of a dominant negative mutant of the FGF receptor disrupts mesoderm formation in Xenopus embryos. Cell (1991) 4.31
Dual inhibition of sister chromatid separation at metaphase. Cell (2001) 4.23
Properties of the kinetochore in vitro. II. Microtubule capture and ATP-dependent translocation. J Cell Biol (1985) 4.21
Splitting the chromosome: cutting the ties that bind sister chromatids. Science (2000) 4.20
Caspase-3-generated fragment of gelsolin: effector of morphological change in apoptosis. Science (1997) 4.19
Phosphorylation of Sic1p by G1 Cdk required for its degradation and entry into S phase. Science (1997) 4.18
Role of phosphorylation in p34cdc2 activation: identification of an activating kinase. Mol Biol Cell (1992) 4.17
Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34. Genes Dev (1999) 4.17
Multiple genes are required for proper insertion of secretory proteins into the endoplasmic reticulum in yeast. J Cell Biol (1989) 4.13
Properties of Saccharomyces cerevisiae wee1 and its differential regulation of p34CDC28 in response to G1 and G2 cyclins. EMBO J (1993) 4.10
Mitotic regulation of the APC activator proteins CDC20 and CDH1. Mol Biol Cell (2000) 4.01
Net1, a Sir2-associated nucleolar protein required for rDNA silencing and nucleolar integrity. Cell (1999) 3.98
Interactions of the COP9 signalosome with the E3 ubiquitin ligase SCFTIRI in mediating auxin response. Science (2001) 3.87
Anaphase-promoting complex/cyclosome-dependent proteolysis of human cyclin A starts at the beginning of mitosis and is not subject to the spindle assembly checkpoint. J Cell Biol (2001) 3.86
Unpolymerized tubulin modulates the level of tubulin mRNAs. Cell (1981) 3.78
Altered constitutive expression of fatty acid-metabolizing enzymes in mice lacking the peroxisome proliferator-activated receptor alpha (PPARalpha). J Biol Chem (1998) 3.78
APC-mediated proteolysis of Ase1 and the morphogenesis of the mitotic spindle. Science (1997) 3.73
Securin is required for chromosomal stability in human cells. Cell (2001) 3.71
Characterization of vertebrate cohesin complexes and their regulation in prophase. J Cell Biol (2000) 3.70
Identification of cell cycle-regulated phosphorylation sites on nuclear lamin C. Cell (1990) 3.67
Control of beta-catenin stability: reconstitution of the cytoplasmic steps of the wnt pathway in Xenopus egg extracts. Mol Cell (2000) 3.65
Microtubules from mammalian brain: some properties of their depolymerization products and a proposed mechanism of assembly and disassembly. Proc Natl Acad Sci U S A (1974) 3.59
Properties of the depolymerization products of microtubules from mammalian brain. Biochemistry (1974) 3.58
Peroxisome proliferator-activated receptor alpha negatively regulates the vascular inflammatory gene response by negative cross-talk with transcription factors NF-kappaB and AP-1. J Biol Chem (1999) 3.57
Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA. Nature (1995) 3.56
Exposure to residential electric and magnetic fields and risk of childhood leukemia. Am J Epidemiol (1991) 3.49
An NSF-like ATPase, p97, and NSF mediate cisternal regrowth from mitotic Golgi fragments. Cell (1995) 3.40
Mechanism of N-WASP activation by CDC42 and phosphatidylinositol 4, 5-bisphosphate. J Cell Biol (2000) 3.39
Emi1 is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex. Cell (2001) 3.36
Proportional mortality among vinyl-chloride workers. Lancet (1974) 3.36
Cohesin cleavage by separase required for anaphase and cytokinesis in human cells. Science (2001) 3.35
A microtubule-associated protein from Xenopus eggs that specifically promotes assembly at the plus-end. J Cell Biol (1987) 3.30
Spontaneous formation of nucleus-like structures around bacteriophage DNA microinjected into Xenopus eggs. Cell (1983) 3.21
Nerve growth factor-induced neurite outgrowth in PC12 cells involves the coordinate induction of microtubule assembly and assembly-promoting factors. J Cell Biol (1985) 3.16
Tau consists of a set of proteins with repeated C-terminal microtubule-binding domains and variable N-terminal domains. Mol Cell Biol (1989) 3.09
Childhood leukemia and parents' occupational and home exposures. J Natl Cancer Inst (1987) 3.03
Mutagenic analysis of the destruction signal of mitotic cyclins and structural characterization of ubiquitinated intermediates. Mol Biol Cell (1996) 2.99
Dispersal of first "workers" in social wasps: causes and implications of an alternative reproductive strategy. Proc Natl Acad Sci U S A (1998) 2.96
Mitotic inactivation of a human SWI/SNF chromatin remodeling complex. Genes Dev (1998) 2.93
Corequirement of specific phosphoinositides and small GTP-binding protein Cdc42 in inducing actin assembly in Xenopus egg extracts. J Cell Biol (1998) 2.90
Tau protein function in living cells. J Cell Biol (1986) 2.89
An antisense mRNA directs the covalent modification of the transcript encoding fibroblast growth factor in Xenopus oocytes. Cell (1989) 2.88
Tau protein binds to microtubules through a flexible array of distributed weak sites. J Cell Biol (1991) 2.85
Nck and phosphatidylinositol 4,5-bisphosphate synergistically activate actin polymerization through the N-WASP-Arp2/3 pathway. J Biol Chem (2001) 2.85
Effects of maternal smoking during pregnancy and environmental tobacco smoke on asthma and wheezing in children. Am J Respir Crit Care Med (2001) 2.82
LIS1 regulates CNS lamination by interacting with mNudE, a central component of the centrosome. Neuron (2000) 2.78
Phosphorylation- and ubiquitin-dependent degradation of the cyclin-dependent kinase inhibitor Far1p in budding yeast. Genes Dev (1997) 2.77
Properties of the kinetochore in vitro. I. Microtubule nucleation and tubulin binding. J Cell Biol (1985) 2.75
INH, a negative regulator of MPF, is a form of protein phosphatase 2A. Cell (1991) 2.73
Regulation of the cell cycle during early Xenopus development. Cell (1984) 2.73
Induction of early mitotic events in a cell-free system. Cell (1985) 2.71
Substrate recognition by the Cdc20 and Cdh1 components of the anaphase-promoting complex. Genes Dev (2001) 2.66
Accumulation of cyclin B1 requires E2F and cyclin-A-dependent rearrangement of the anaphase-promoting complex. Nature (1999) 2.63
Identification of a cullin homology region in a subunit of the anaphase-promoting complex. Science (1998) 2.61
Cell cycle- and cell growth-regulated proteolysis of mammalian CDC6 is dependent on APC-CDH1. Genes Dev (2000) 2.58
SEL-10 is an inhibitor of notch signaling that targets notch for ubiquitin-mediated protein degradation. Mol Cell Biol (2001) 2.56
Occupational exposures of parents of children with acute nonlymphocytic leukemia: a report from the Childrens Cancer Study Group. Cancer Res (1989) 2.55