Maturation stages of mouse dendritic cells in growth factor-dependent long-term cultures.

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Published in J Exp Med on January 20, 1997

Authors

C Winzler1, P Rovere, M Rescigno, F Granucci, G Penna, L Adorini, V S Zimmermann, J Davoust, P Ricciardi-Castagnoli

Author Affiliations

1: CNR Centre of Cellular and Molecular Pharmacology, Milan, Italy.

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Microtubules are stabilized in confluent epithelial cells but not in fibroblasts. J Cell Biol (1990) 1.69

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Microtubules are stabilized in confluent epithelial cells but not in fibroblasts. J Cell Biol (1990) 1.69

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Asymmetric lateral mobility of phospholipids in the human erythrocyte membrane. Proc Natl Acad Sci U S A (1986) 1.41

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Establishment, characterization and virus expression of cell lines derived from radiation- and virus-induced lymphomas of C57BL/Ka mice. Int J Cancer (1979) 1.35

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