Published in Genome Res on April 01, 1997
A computer program for aligning a cDNA sequence with a genomic DNA sequence. Genome Res (1998) 22.69
PipMaker--a web server for aligning two genomic DNA sequences. Genome Res (2000) 17.46
Covariation in frequencies of substitution, deletion, transposition, and recombination during eutherian evolution. Genome Res (2003) 11.12
Highly conserved non-coding sequences are associated with vertebrate development. PLoS Biol (2004) 10.59
Human and mouse gene structure: comparative analysis and application to exon prediction. Genome Res (2000) 8.28
rVista for comparative sequence-based discovery of functional transcription factor binding sites. Genome Res (2002) 7.33
Active conservation of noncoding sequences revealed by three-way species comparisons. Genome Res (2000) 6.18
Strategies and tools for whole-genome alignments. Genome Res (2003) 4.86
Comparative analysis of noncoding regions of 77 orthologous mouse and human gene pairs. Genome Res (1999) 4.50
zPicture: dynamic alignment and visualization tool for analyzing conservation profiles. Genome Res (2004) 4.26
Leveraging the mouse genome for gene prediction in human: from whole-genome shotgun reads to a global synteny map. Genome Res (2003) 3.18
Evolutionarily conserved sequences on human chromosome 21. Genome Res (2001) 2.95
Detection and visualization of compositionally similar cis-regulatory element clusters in orthologous and coordinately controlled genes. Genome Res (2002) 2.60
Long-range comparison of human and mouse SCL loci: localized regions of sensitivity to restriction endonucleases correspond precisely with peaks of conserved noncoding sequences. Genome Res (2001) 2.04
Comparative sequence of human and mouse BAC clones from the mnd2 region of chromosome 2p13. Genome Res (1999) 1.94
Generation and comparative analysis of approximately 3.3 Mb of mouse genomic sequence orthologous to the region of human chromosome 7q11.23 implicated in Williams syndrome. Genome Res (2002) 1.80
Human and mouse alpha-synuclein genes: comparative genomic sequence analysis and identification of a novel gene regulatory element. Genome Res (2001) 1.65
Of mice and men: phylogenetic footprinting aids the discovery of regulatory elements. J Biol (2003) 1.57
Characterization of the genomic Xist locus in rodents reveals conservation of overall gene structure and tandem repeats but rapid evolution of unique sequence. Genome Res (2001) 1.54
Generation and analysis of 25 Mb of genomic DNA from the pufferfish Fugu rubripes by sequence scanning. Genome Res (1999) 1.47
CONFAC: automated application of comparative genomic promoter analysis to DNA microarray datasets. Nucleic Acids Res (2004) 1.44
Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse. Genome Res (2003) 1.32
Comparative genomic sequencing identifies novel tissue-specific enhancers and sequence elements for methylation-sensitive factors implicated in Igf2/H19 imprinting. Genome Res (2000) 1.30
Comparative sequence and x-inactivation analyses of a domain of escape in human xp11.2 and the conserved segment in mouse. Genome Res (2004) 1.29
Microarray and comparative genomics-based identification of genes and gene regulatory regions of the mouse immune system. BMC Genomics (2004) 1.25
Comparative genomic sequence analysis of the human and mouse cystic fibrosis transmembrane conductance regulator genes. Proc Natl Acad Sci U S A (2000) 1.19
Alfresco--a workbench for comparative genomic sequence analysis. Genome Res (2000) 1.19
Sequence conservation at human and mouse orthologous common fragile regions, FRA3B/FHIT and Fra14A2/Fhit. Proc Natl Acad Sci U S A (2001) 1.15
Analysis of the cat eye syndrome critical region in humans and the region of conserved synteny in mice: a search for candidate genes at or near the human chromosome 22 pericentromere. Genome Res (2001) 1.14
Comparative genome sequence analysis of the Bpa/Str region in mouse and Man. Genome Res (2000) 1.13
Fragile site orthologs FHIT/FRA3B and Fhit/Fra14A2: evolutionarily conserved but highly recombinogenic. Proc Natl Acad Sci U S A (2003) 1.09
Genomic sequence analysis of the mouse Naip gene array. Genome Res (2000) 1.08
Development of B-lineage predominant lentiviral vectors for use in genetic therapies for B cell disorders. Mol Ther (2010) 1.04
Severe B cell deficiency and disrupted splenic architecture in transgenic mice expressing the E41K mutated form of Bruton's tyrosine kinase. EMBO J (1998) 1.01
Comparative analysis of the alpha-like globin clusters in mouse, rat, and human chromosomes indicates a mechanism underlying breaks in conserved synteny. Genome Res (2004) 0.96
BTKbase, mutation database for X-linked agammaglobulinemia (XLA). Nucleic Acids Res (1998) 0.94
Experimental validation of novel genes predicted in the un-annotated regions of the Arabidopsis genome. BMC Genomics (2007) 0.91
Mouse models of genetic disease: new approaches, new paradigms. J Inherit Metab Dis (1998) 0.90
A systems approach to mapping transcriptional networks controlling surfactant homeostasis. BMC Genomics (2010) 0.86
Btk expression is controlled by Oct and BOB.1/OBF.1. Nucleic Acids Res (2006) 0.83
A genome-wide cis-regulatory element discovery method based on promoter sequences and gene co-expression networks. BMC Genomics (2013) 0.80
Strong conservation of the human NF2 locus based on sequence comparison in five species. Mamm Genome (2003) 0.77
Comparative gene mapping in cattle, Indian muntjac, and Chinese muntjac by fluorescence in situ hybridization. Genetica (2008) 0.77
Genomic promoter analysis predicts functional transcription factor binding. Adv Bioinformatics (2008) 0.75
Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res (1997) 665.31
Basic local alignment search tool. J Mol Biol (1990) 659.07
Initial sequencing and analysis of the human genome. Nature (2001) 212.86
The genome sequence of Drosophila melanogaster. Science (2000) 74.32
A greedy algorithm for aligning DNA sequences. J Comput Biol (2000) 47.89
Optimal alignments in linear space. Comput Appl Biosci (1988) 38.10
Protein sequence similarity searches using patterns as seeds. Nucleic Acids Res (1998) 23.87
The UCSC Genome Browser Database: 2008 update. Nucleic Acids Res (2007) 23.13
A computer program for aligning a cDNA sequence with a genomic DNA sequence. Genome Res (1998) 22.69
Aligning two sequences within a specified diagonal band. Comput Appl Biosci (1992) 19.31
PipMaker--a web server for aligning two genomic DNA sequences. Genome Res (2000) 17.46
Complete genome sequence of Salmonella enterica serovar Typhimurium LT2. Nature (2001) 16.89
Comparative analyses of multi-species sequences from targeted genomic regions. Nature (2003) 13.31
Methylation of HpaII and HhaI sites near the polymorphic CAG repeat in the human androgen-receptor gene correlates with X chromosome inactivation. Am J Hum Genet (1992) 11.38
Identification of a coordinate regulator of interleukins 4, 13, and 5 by cross-species sequence comparisons. Science (2000) 10.14
Deletion screening of the Duchenne muscular dystrophy locus via multiplex DNA amplification. Nucleic Acids Res (1988) 9.94
Long human-mouse sequence alignments reveal novel regulatory elements: a reason to sequence the mouse genome. Genome Res (1997) 8.49
Scoring pairwise genomic sequence alignments. Pac Symp Biocomput (2002) 8.42
Comparison of DNA sequences with protein sequences. Genomics (1997) 7.76
Mapping sequenced E.coli genes by computer: software, strategies and examples. Nucleic Acids Res (1991) 6.29
Generation of cDNA probes directed by amino acid sequence: cloning of urate oxidase. Science (1988) 5.72
Alignment of Escherichia coli K12 DNA sequences to a genomic restriction map. Nucleic Acids Res (1990) 4.07
A controlled trial of a formalin-inactivated hepatitis A vaccine in healthy children. N Engl J Med (1992) 4.05
Comparative sequence analysis of a gene-rich cluster at human chromosome 12p13 and its syntenic region in mouse chromosome 6. Genome Res (1998) 3.80
Locus control regions of mammalian beta-globin gene clusters: combining phylogenetic analyses and experimental results to gain functional insights. Gene (1997) 3.77
The natural history of recurrent herpes simplex labialis: implications for antiviral therapy. N Engl J Med (1977) 3.61
A local alignment tool for very long DNA sequences. Comput Appl Biosci (1995) 3.58
Use of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia (APL): I. As2O3 exerts dose-dependent dual effects on APL cells. Blood (1997) 3.56
A BAC-based physical map of the major autosomes of Drosophila melanogaster. Science (2000) 3.51
A recombination hotspot responsible for two inherited peripheral neuropathies is located near a mariner transposon-like element. Nat Genet (1996) 3.45
Post-processing long pairwise alignments. Bioinformatics (1999) 3.00
A space-efficient algorithm for local similarities. Comput Appl Biosci (1990) 2.98
Modulation of the two promoters of the galactose operon of Escherichia coli. Nature (1979) 2.91
Comparative analysis of the gene-dense ACHE/TFR2 region on human chromosome 7q22 with the orthologous region on mouse chromosome 5. Nucleic Acids Res (2001) 2.89
Polycystic ovaries treated by laparoscopic laser vaporization. Fertil Steril (1989) 2.77
Decreased expression of myotonin-protein kinase messenger RNA and protein in adult form of myotonic dystrophy. Science (1993) 2.75
Analysis of the quality and utility of random shotgun sequencing at low redundancies. Genome Res (1998) 2.74
Correlation of the highest-energy cosmic rays with nearby extragalactic objects. Science (2007) 2.57
Metabolism of (14C) cefaclor, a cephalosporin antibiotic, in three species of laboratory animals. Antimicrob Agents Chemother (1976) 2.52
Comparative genome analysis delimits a chromosomal domain and identifies key regulatory elements in the alpha globin cluster. Hum Mol Genet (2001) 2.46
Multiplex PCR: advantages, development, and applications. PCR Methods Appl (1994) 2.42
Treatment of moderate/severe acute graft-versus-host disease after allogeneic bone marrow transplantation: an analysis of clinical risk features and outcome. Blood (1990) 2.38
Globin gene server: a prototype E-mail database server featuring extensive multiple alignments and data compilation for electronic genetic analysis. Genomics (1994) 2.36
Two independent mutational events in the loss of urate oxidase during hominoid evolution. J Mol Evol (1992) 2.35
PCR test for cystic fibrosis deletion. Nature (1990) 2.26
Comparison of five methods for finding conserved sequences in multiple alignments of gene regulatory regions. Nucleic Acids Res (1999) 2.19
Large-scale concatenation cDNA sequencing. Genome Res (1997) 2.18
Long HIV-1 incubation periods and dynamics of transmission within a family. Lancet (1990) 2.17
Large-scale sequencing in human chromosome 12p13: experimental and computational gene structure determination. Genome Res (1997) 2.17
The molecular basis of the sparse fur mouse mutation. Science (1987) 2.09
Comparison of the Escherichia coli K-12 genome with sampled genomes of a Klebsiella pneumoniae and three salmonella enterica serovars, Typhimurium, Typhi and Paratyphi. Nucleic Acids Res (2000) 2.07
Recommendations from an international expert panel on the use of neoadjuvant (primary) systemic treatment of operable breast cancer: new perspectives 2006. Ann Oncol (2007) 2.05
Simultaneous shotgun sequencing of multiple cDNA clones. DNA Seq (1997) 2.04
The Chinese hamster HPRT gene: restriction map, sequence analysis, and multiplex PCR deletion screen. Genomics (1991) 2.03
Characterization of the human and mouse unconventional myosin XV genes responsible for hereditary deafness DFNB3 and shaker 2. Genomics (1999) 1.97
A tool for aligning very similar DNA sequences. Comput Appl Biosci (1997) 1.97
Alignments without low-scoring regions. J Comput Biol (1998) 1.96
A sensitive reporter cell line for HIV-1 tat activity, HIV-1 inhibitors, and T cell activation effects. AIDS Res Hum Retroviruses (1994) 1.95
Termination of DNA synthesis by novel 3'-modified-deoxyribonucleoside 5'-triphosphates. Nucleic Acids Res (1994) 1.95
Comparative sequence of human and mouse BAC clones from the mnd2 region of chromosome 2p13. Genome Res (1999) 1.94
Duplication of a gene-rich cluster between 16p11.1 and Xq28: a novel pericentromeric-directed mechanism for paralogous genome evolution. Hum Mol Genet (1996) 1.93
Carrier detection and prenatal diagnosis in Duchenne and Becker muscular dystrophy families, using dinucleotide repeat polymorphisms. Am J Hum Genet (1991) 1.93
Diabetes mellitus: an underestimated public health program. J Chronic Dis (1975) 1.87
Pentanucleotide repeat length polymorphism at the human CD4 locus. Nucleic Acids Res (1991) 1.85
Sequence and comparative analysis of the mouse 1-megabase region orthologous to the human 11p15 imprinted domain. Genome Res (2000) 1.85
Urate oxidase: primary structure and evolutionary implications. Proc Natl Acad Sci U S A (1989) 1.85
RNA secondary structure analysis of the packaging signal for Moloney murine leukemia virus. Virology (1991) 1.84
A "double adaptor" method for improved shotgun library construction. Anal Biochem (1996) 1.81
Identification and localization of mutations at the Lesch-Nyhan locus by ribonuclease A cleavage. Science (1987) 1.76
Electrophoretically uniform fluorescent dyes for automated DNA sequencing. Science (1996) 1.75
Chaining multiple-alignment blocks. J Comput Biol (1994) 1.75
Genome sequence comparisons: hurdles in the fast lane to functional genomics. Brief Bioinform (2000) 1.71
Expression of the murine Duchenne muscular dystrophy gene in muscle and brain. Science (1988) 1.70
Accuracy of bedside chest hard-copy screen-film versus hard- and soft-copy computed radiographs in a medical intensive care unit: receiver operating characteristic analysis. Radiology (1997) 1.69
Software tools for analyzing pairwise alignments of long sequences. Nucleic Acids Res (1991) 1.68
Approximate matching of regular expressions. Bull Math Biol (1989) 1.68
Positive and negative regulatory elements of the rabbit embryonic epsilon-globin gene revealed by an improved multiple alignment program and functional analysis. DNA Seq (1993) 1.66
A gene-rich cluster between the CD4 and triosephosphate isomerase genes at human chromosome 12p13. Genome Res (1996) 1.66
Dynamic programming algorithms for biological sequence comparison. Methods Enzymol (1992) 1.65
The Paced Auditory Serial Addition Task (PASAT): norms for age, education, and ethnicity. Assessment (1998) 1.65
Racism, society, and disease: an exploration of the social and biological mechanisms of differential mortality. Int J Health Serv (1981) 1.62
A clone-array pooled shotgun strategy for sequencing large genomes. Genome Res (2001) 1.60
Conserved E boxes function as part of the enhancer in hypersensitive site 2 of the beta-globin locus control region. Role of basic helix-loop-helix proteins. J Biol Chem (1997) 1.58
Evolution of human immunodeficiency virus type 1 nucleotide sequence diversity among close contacts. Proc Natl Acad Sci U S A (1991) 1.58
Analysis of human immunodeficiency virus type 1 integrase mutants. Virology (1995) 1.58
Disruption of the adenosine deaminase gene causes hepatocellular impairment and perinatal lethality in mice. Proc Natl Acad Sci U S A (1995) 1.54