Discovery and biological activity of orally active peptidyl trifluoromethyl ketone inhibitors of human neutrophil elastase.

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Published in J Med Chem on June 06, 1997

Authors

P D Edwards1, D W Andisik, C A Bryant, B Ewing, B Gomes, J J Lewis, D Rakiewicz, G Steelman, A Strimpler, D A Trainor, P A Tuthill, R C Mauger, C A Veale, R A Wildonger, J C Williams, D J Wolanin, M Zottola

Author Affiliations

1: Department of Medicinal Chemistry, ZENECA Pharmaceuticals, A Business Unit of ZENECA Inc., Wilmington, Delaware 19850-5437, USA.

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