Serum factors releasing serotonin from normal platelets: relation to the manifestations of systemic lupus erythematosus.

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🔗 View Article (PMID 921084)

Published in Ann Intern Med on November 01, 1977

Authors

M H Ginsberg, M O'Malley

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PEA-15 mediates cytoplasmic sequestration of ERK MAP kinase. Dev Cell (2001) 2.73

Chronic neurological sequelae to organophosphate pesticide poisoning. Am J Public Health (1994) 2.70

The effect of Arg-Gly-Asp-containing peptides on fibrinogen and von Willebrand factor binding to platelets. Proc Natl Acad Sci U S A (1985) 2.64

Arginyl-glycyl-aspartic acid (RGD): a cell adhesion motif. Trends Biochem Sci (1991) 2.62

Complementation of dominant suppression implicates CD98 in integrin activation. Nature (1997) 2.62

Binding of paxillin to alpha4 integrins modifies integrin-dependent biological responses. Nature (1999) 2.59

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beta3 Integrins mediate the cellular entry of hantaviruses that cause respiratory failure. Proc Natl Acad Sci U S A (1998) 2.54

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A beta 3 integrin mutation abolishes ligand binding and alters divalent cation-dependent conformation. Science (1990) 2.42

Integrin activation and cytoskeletal interaction are essential for the assembly of a fibronectin matrix. Cell (1995) 2.36

Monoclonal antibodies to ligand-occupied conformers of integrin alpha IIb beta 3 (glycoprotein IIb-IIIa) alter receptor affinity, specificity, and function. J Biol Chem (1991) 2.34

Specific and saturable binding of plasma fibronectin to thrombin-stimulated human platelets. J Biol Chem (1981) 2.31

Increased filamin binding to beta-integrin cytoplasmic domains inhibits cell migration. Nat Cell Biol (2001) 2.29

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Integrin beta cytoplasmic domains differentially bind to cytoskeletal proteins. J Biol Chem (1998) 2.19

Selective inhibition of integrin function by antibodies specific for ligand-occupied receptor conformers. J Biol Chem (1990) 2.16

A platelet alpha granule membrane protein that is associated with the plasma membrane after activation. Characterization and subcellular localization of platelet activation-dependent granule-external membrane protein. J Clin Invest (1986) 2.13

Distinct functions of integrin alpha and beta subunit cytoplasmic domains in cell spreading and formation of focal adhesions. J Cell Biol (1993) 2.08

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Regulation of the protein tyrosine kinase pp72syk by platelet agonists and the integrin alpha IIb beta 3. J Biol Chem (1994) 1.93

Trans-dominant inhibition of integrin function. Mol Biol Cell (1996) 1.92

Affinity modulation of integrin alpha 5 beta 1: regulation of the functional response by soluble fibronectin. J Cell Biol (1993) 1.86

Evidence that three adhesive proteins interact with a common recognition site on activated platelets. J Biol Chem (1984) 1.83

Immunochemical and amino-terminal sequence comparison of two cytoadhesins indicates they contain similar or identical beta subunits and distinct alpha subunits. J Biol Chem (1987) 1.82

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NMR analysis of structure and dynamics of the cytosolic tails of integrin alpha IIb beta 3 in aqueous solution. Biochemistry (2001) 1.76

Long range propagation of conformational changes in integrin alpha IIb beta 3. J Biol Chem (1993) 1.73

A point mutation in the integrin beta 3 cytoplasmic domain (S752-->P) impairs bidirectional signaling through alpha IIb beta 3 (platelet glycoprotein IIb-IIIa). Blood (1994) 1.71

Effect of platelet activation on the conformation of the plasma membrane glycoprotein IIb-IIIa complex. J Biol Chem (1991) 1.67

The ligand binding site of the platelet integrin receptor GPIIb-IIIa is proximal to the second calcium binding domain of its alpha subunit. J Biol Chem (1990) 1.66

Integrin-mediated cell adhesion: the extracellular face. J Biol Chem (1994) 1.66

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Calpain cleavage of the cytoplasmic domain of the integrin beta 3 subunit. J Biol Chem (1995) 1.59

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A unique recognition site mediates the interaction of fibrinogen with the leukocyte integrin Mac-1 (CD11b/CD18). J Biol Chem (1990) 1.49

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Occupancy of an adhesive glycoprotein receptor modulates expression of an antigenic site involved in cell adhesion. J Biol Chem (1988) 1.47

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The inner world of cell adhesion: integrin cytoplasmic domains. Trends Cell Biol (1994) 1.44

"Inside-out" signal transduction inhibited by isolated integrin cytoplasmic domains. J Biol Chem (1994) 1.43

Evidence that arginyl-glycyl-aspartate peptides and fibrinogen gamma chain peptides share a common binding site on platelets. J Biol Chem (1987) 1.41

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Rheumatoid nodulosis: an unusual variant of rheumatoid disease. Arthritis Rheum (1975) 1.19