Published in Mol Biol Cell on July 01, 1997
Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development. J Cell Biol (2003) 10.10
The dynamin-related GTPase Dnm1 regulates mitochondrial fission in yeast. Nat Cell Biol (1999) 6.26
Mitochondria: in sickness and in health. Cell (2012) 6.05
Roles of the mammalian mitochondrial fission and fusion mediators Fis1, Drp1, and Opa1 in apoptosis. Mol Biol Cell (2004) 5.94
Dnm1p GTPase-mediated mitochondrial fission is a multi-step process requiring the novel integral membrane component Fis1p. J Cell Biol (2000) 5.86
Chemical inhibition of the mitochondrial division dynamin reveals its role in Bax/Bak-dependent mitochondrial outer membrane permeabilization. Dev Cell (2008) 5.67
Division versus fusion: Dnm1p and Fzo1p antagonistically regulate mitochondrial shape. J Cell Biol (1999) 5.53
Mitochondrial fusion in yeast requires the transmembrane GTPase Fzo1p. J Cell Biol (1998) 5.21
Mitochondrial fusion in human cells is efficient, requires the inner membrane potential, and is mediated by mitofusins. Mol Biol Cell (2002) 4.48
Mitochondrial fragmentation in neurodegeneration. Nat Rev Neurosci (2008) 4.32
Mdv1p is a WD repeat protein that interacts with the dynamin-related GTPase, Dnm1p, to trigger mitochondrial division. J Cell Biol (2000) 4.07
The mitochondrial E3 ubiquitin ligase MARCH5 is required for Drp1 dependent mitochondrial division. J Cell Biol (2007) 3.83
Mutants affecting the structure of the cortical endoplasmic reticulum in Saccharomyces cerevisiae. J Cell Biol (2000) 3.73
Tubular network formation protects mitochondria from autophagosomal degradation during nutrient starvation. Proc Natl Acad Sci U S A (2011) 3.49
Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell (2002) 3.27
MARCH-V is a novel mitofusin 2- and Drp1-binding protein able to change mitochondrial morphology. EMBO Rep (2006) 3.19
Mitochondrial dynamics and division in budding yeast. Trends Cell Biol (2002) 3.15
The dynamin-related GTPase, Mgm1p, is an intermembrane space protein required for maintenance of fusion competent mitochondria. J Cell Biol (2000) 3.14
The WD repeat protein, Mdv1p, functions as a molecular adaptor by interacting with Dnm1p and Fis1p during mitochondrial fission. J Cell Biol (2002) 2.74
Mgm1p, a dynamin-related GTPase, is essential for fusion of the mitochondrial outer membrane. Mol Biol Cell (2003) 2.49
The intramitochondrial dynamin-related GTPase, Mgm1p, is a component of a protein complex that mediates mitochondrial fusion. J Cell Biol (2003) 2.45
Yeast Miro GTPase, Gem1p, regulates mitochondrial morphology via a novel pathway. J Cell Biol (2004) 2.42
Mitochondrial fission proteins regulate programmed cell death in yeast. Genes Dev (2004) 2.30
Mgm101p is a novel component of the mitochondrial nucleoid that binds DNA and is required for the repair of oxidatively damaged mitochondrial DNA. J Cell Biol (1999) 2.22
The functional organization of mitochondrial genomes in human cells. BMC Biol (2004) 2.20
Fast 100-nm resolution three-dimensional microscope reveals structural plasticity of mitochondria in live yeast. Proc Natl Acad Sci U S A (2002) 2.19
UGO1 encodes an outer membrane protein required for mitochondrial fusion. J Cell Biol (2001) 2.18
Division of mitochondria requires a novel DMN1-interacting protein, Net2p. Mol Biol Cell (2001) 2.17
A protein complex containing Mdm10p, Mdm12p, and Mmm1p links mitochondrial membranes and DNA to the cytoskeleton-based segregation machinery. Mol Biol Cell (2003) 2.14
Yeast peroxisomes multiply by growth and division. J Cell Biol (2007) 2.07
Maintenance and integrity of the mitochondrial genome: a plethora of nuclear genes in the budding yeast. Microbiol Mol Biol Rev (2000) 2.02
Frequent fusion and fission of plant mitochondria with unequal nucleoid distribution. Proc Natl Acad Sci U S A (2004) 2.01
Constriction and Dnm1p recruitment are distinct processes in mitochondrial fission. Mol Biol Cell (2003) 1.98
The sorting of mitochondrial DNA and mitochondrial proteins in zygotes: preferential transmission of mitochondrial DNA to the medial bud. J Cell Biol (1998) 1.96
Evidence for a two membrane-spanning autonomous mitochondrial DNA replisome. J Cell Biol (2003) 1.92
OPA1 processing reconstituted in yeast depends on the subunit composition of the m-AAA protease in mitochondria. Mol Biol Cell (2007) 1.87
Functions of the high mobility group protein, Abf2p, in mitochondrial DNA segregation, recombination and copy number in Saccharomyces cerevisiae. Genetics (1998) 1.85
Mdm30 is an F-box protein required for maintenance of fusion-competent mitochondria in yeast. Mol Biol Cell (2003) 1.76
Mitochondrial loss, dysfunction and altered dynamics in Huntington's disease. Hum Mol Genet (2010) 1.62
Role of essential genes in mitochondrial morphogenesis in Saccharomyces cerevisiae. Mol Biol Cell (2005) 1.61
Connection of the mitochondrial outer and inner membranes by Fzo1 is critical for organellar fusion. J Cell Biol (2001) 1.60
A splice-isoform of vesicle-associated membrane protein-1 (VAMP-1) contains a mitochondrial targeting signal. Mol Biol Cell (1998) 1.53
ER-associated mitochondrial division links the distribution of mitochondria and mitochondrial DNA in yeast. Elife (2013) 1.52
Mitochondrial fusion and division: Regulation and role in cell viability. Semin Cell Dev Biol (2009) 1.51
Regulation of mitochondrial morphology by USP30, a deubiquitinating enzyme present in the mitochondrial outer membrane. Mol Biol Cell (2008) 1.48
Merging mitochondria matters: cellular role and molecular machinery of mitochondrial fusion. EMBO Rep (2002) 1.47
The GTPase effector domain sequence of the Dnm1p GTPase regulates self-assembly and controls a rate-limiting step in mitochondrial fission. Mol Biol Cell (2001) 1.46
Cytoplasmic recycling of 60S preribosomal factors depends on the AAA protein Drg1. Mol Cell Biol (2007) 1.46
Mitochondrial dynamics in diabetes. Antioxid Redox Signal (2010) 1.46
Mitochondrial network size scaling in budding yeast. Science (2012) 1.44
Interchangeable adaptors regulate mitochondrial dynamin assembly for membrane scission. Proc Natl Acad Sci U S A (2013) 1.39
The dynamin-like GTPase Sey1p mediates homotypic ER fusion in S. cerevisiae. J Cell Biol (2012) 1.38
The numbers of individual mitochondrial DNA molecules and mitochondrial DNA nucleoids in yeast are co-regulated by the general amino acid control pathway. EMBO J (2000) 1.35
Mdm31 and Mdm32 are inner membrane proteins required for maintenance of mitochondrial shape and stability of mitochondrial DNA nucleoids in yeast. J Cell Biol (2005) 1.33
Charcot-Marie-Tooth neuropathy type 2A: novel mutations in the mitofusin 2 gene (MFN2). BMC Med Genet (2006) 1.31
Cardiolipin and mitochondrial phosphatidylethanolamine have overlapping functions in mitochondrial fusion in Saccharomyces cerevisiae. J Biol Chem (2012) 1.30
The inner membrane protein Mdm33 controls mitochondrial morphology in yeast. J Cell Biol (2003) 1.22
Biogenesis and dynamics of mitochondria during the cell cycle: significance of 3'UTRs. PLoS One (2006) 1.22
Intraocular pressure elevation induces mitochondrial fission and triggers OPA1 release in glaucomatous optic nerve. Invest Ophthalmol Vis Sci (2008) 1.20
Mitochondrial inheritance is delayed in Saccharomyces cerevisiae cells lacking the serine/threonine phosphatase PTC1. Mol Biol Cell (1998) 1.19
Nonredundant roles of mitochondria-associated F-box proteins Mfb1 and Mdm30 in maintenance of mitochondrial morphology in yeast. Mol Biol Cell (2006) 1.19
Mechanisms of human mitochondrial DNA maintenance: the determining role of primary sequence and length over function. Mol Biol Cell (1999) 1.17
Mitochondrial protein synthesis, import, and assembly. Genetics (2012) 1.17
A mutation in a novel yeast proteasomal gene, RPN11/MPR1, produces a cell cycle arrest, overreplication of nuclear and mitochondrial DNA, and an altered mitochondrial morphology. Mol Biol Cell (1998) 1.16
Elevated hydrostatic pressure triggers release of OPA1 and cytochrome C, and induces apoptotic cell death in differentiated RGC-5 cells. Mol Vis (2009) 1.15
Importance of mitochondrial dynamics during meiosis and sporulation. Mol Biol Cell (2004) 1.14
Memantine blocks mitochondrial OPA1 and cytochrome c release and subsequent apoptotic cell death in glaucomatous retina. Invest Ophthalmol Vis Sci (2008) 1.12
Changes in organization of Crithidia fasciculata kinetoplast DNA replication proteins during the cell cycle. J Cell Biol (1998) 1.11
In vivo methylation of mtDNA reveals the dynamics of protein-mtDNA interactions. Nucleic Acids Res (2009) 1.10
Glutamate receptor activation triggers OPA1 release and induces apoptotic cell death in ischemic rat retina. Mol Vis (2008) 1.09
Shaping the dynamic mitochondrial network. BMC Biol (2014) 1.08
A mutation associated with CMT2A neuropathy causes defects in Fzo1 GTP hydrolysis, ubiquitylation, and protein turnover. Mol Biol Cell (2009) 1.08
Replication and preferential inheritance of hypersuppressive petite mitochondrial DNA. EMBO J (2001) 1.07
Dynamin assembly strategies and adaptor proteins in mitochondrial fission. Curr Biol (2013) 1.07
Dissection of the carboxyl-terminal domain of the proteasomal subunit Rpn11 in maintenance of mitochondrial structure and function. Mol Biol Cell (2008) 1.05
Recombination-dependent mtDNA partitioning: in vivo role of Mhr1p to promote pairing of homologous DNA. EMBO J (2002) 1.05
Cytoskeletal-assisted dynamics of the mitochondrial reticulum in living cells. Proc Natl Acad Sci U S A (2002) 1.02
Mitochondrial fusion proteins and human diseases. Neurol Res Int (2013) 1.02
Increased optic atrophy type 1 expression protects retinal ganglion cells in a mouse model of glaucoma. Mol Vis (2010) 1.00
Two Dictyostelium orthologs of the prokaryotic cell division protein FtsZ localize to mitochondria and are required for the maintenance of normal mitochondrial morphology. Eukaryot Cell (2003) 0.99
Genotypic stability, segregation and selection in heteroplasmic human cell lines containing np 3243 mutant mtDNA. Genetics (2000) 0.99
Canonical Wnt signaling protects hippocampal neurons from Aβ oligomers: role of non-canonical Wnt-5a/Ca(2+) in mitochondrial dynamics. Front Cell Neurosci (2013) 0.98
Deceleration of fusion-fission cycles improves mitochondrial quality control during aging. PLoS Comput Biol (2012) 0.97
The Ustilago maydis a2 mating-type locus genes lga2 and rga2 compromise pathogenicity in the absence of the mitochondrial p32 family protein Mrb1. Plant Cell (2004) 0.96
Mitochondrial network morphology: building an integrative, geometrical view. BMC Biol (2013) 0.92
Dynamics of the mitochondrial reticulum in live cells using Fourier imaging correlation spectroscopy and digital video microscopy. Biophys J (2000) 0.92
G-protein β2 subunit interacts with mitofusin 1 to regulate mitochondrial fusion. Nat Commun (2010) 0.91
Genetic conservation versus variability in mitochondria: the architecture of the mitochondrial genome in the petite-negative yeast Schizosaccharomyces pombe. Curr Genet (2003) 0.90
Mitochondrial motility and vascular smooth muscle proliferation. Arterioscler Thromb Vasc Biol (2012) 0.90
Mitochondria and heart failure: new insights into an energetic problem. Minerva Cardioangiol (2010) 0.90
Mhr1p-dependent concatemeric mitochondrial DNA formation for generating yeast mitochondrial homoplasmic cells. Mol Biol Cell (2003) 0.89
Dynamic tubulation of mitochondria drives mitochondrial network formation. Cell Res (2015) 0.89
Reevaluation of the role of Pex1 and dynamin-related proteins in peroxisome membrane biogenesis. J Cell Biol (2015) 0.88
The neurogenic basic helix-loop-helix transcription factor NeuroD6 concomitantly increases mitochondrial mass and regulates cytoskeletal organization in the early stages of neuronal differentiation. ASN Neuro (2009) 0.87
Structural and functional characterizations of mung bean mitochondrial nucleoids. Nucleic Acids Res (2005) 0.85
MFN2 couples glutamate excitotoxicity and mitochondrial dysfunction in motor neurons. J Biol Chem (2014) 0.83
Mitochondrial dysfunction in inflammatory bowel disease. Front Cell Dev Biol (2015) 0.83
A heritable structural alteration of the yeast mitochondrion. Genetics (2002) 0.82
Quality matters: how does mitochondrial network dynamics and quality control impact on mtDNA integrity? Philos Trans R Soc Lond B Biol Sci (2014) 0.82
Interspecies mitochondrial fusion between mouse and human mitochondria is rapid and efficient. Mitochondrion (2006) 0.82
Green fluorescent protein as a marker for gene expression. Science (1994) 34.55
Localization of mitochondria in living cells with rhodamine 123. Proc Natl Acad Sci U S A (1980) 7.31
Fluorescence microscopy in three dimensions. Methods Cell Biol (1989) 6.70
A fusion protein required for vesicle-mediated transport in both mammalian cells and yeast. Nature (1989) 6.48
Dynamics of mitochondria in living cells: shape changes, dislocations, fusion, and fission of mitochondria. Microsc Res Tech (1994) 5.34
Characterization of a component of the yeast secretion machinery: identification of the SEC18 gene product. Mol Cell Biol (1988) 3.74
Regulation of mitochondrial morphology and inheritance by Mdm10p, a protein of the mitochondrial outer membrane. J Cell Biol (1994) 3.53
Membrane fusion and the cell cycle: Cdc48p participates in the fusion of ER membranes. Cell (1995) 3.44
The microtubule-dependent formation of a tubulovesicular network with characteristics of the ER from cultured cell extracts. Cell (1988) 3.34
MMM1 encodes a mitochondrial outer membrane protein essential for establishing and maintaining the structure of yeast mitochondria. J Cell Biol (1994) 3.31
Temperature-sensitive yeast mutants defective in mitochondrial inheritance. J Cell Biol (1990) 3.08
Mitochondrial DNA maintenance in yeast requires a protein containing a region related to the GTP-binding domain of dynamin. Genes Dev (1992) 3.04
Organelle inheritance. Cell (1996) 2.96
Basal body movements as a mechanism for mitochondrial genome segregation in the trypanosome cell cycle. Nature (1991) 2.93
Vectors for constitutive and inducible gene expression in yeast. Methods Enzymol (1991) 2.88
Microtubule polarity and dynamics in the control of organelle positioning, segregation, and cytokinesis in the trypanosome cell cycle. J Cell Biol (1995) 2.85
The yeast gene, MDM20, is necessary for mitochondrial inheritance and organization of the actin cytoskeleton. J Cell Biol (1997) 2.44
Mitochondrion of yeast: ultrastructural evidence for one giant, branched organelle per cell. Science (1973) 2.42
Normal mitochondrial structure and genome maintenance in yeast requires the dynamin-like product of the MGM1 gene. Curr Genet (1993) 2.29
A mitochondrial protease with two catalytic subunits of nonoverlapping specificities. Science (1993) 2.28
Actin-dependent mitochondrial motility in mitotic yeast and cell-free systems: identification of a motor activity on the mitochondrial surface. J Cell Biol (1995) 2.23
Fluorescence microscopic studies of mitochondrial nucleoids during meiosis and sporulation in the yeast, Saccharomyces cerevisiae. J Cell Sci (1984) 2.13
Nuclear and mitochondrial inheritance in yeast depends on novel cytoplasmic structures defined by the MDM1 protein. J Cell Biol (1992) 1.90
Formation of membrane networks in vitro by kinesin-driven microtubule movement. J Cell Biol (1988) 1.81
Patterns of mitochondrial sorting in yeast zygotes. Mol Biol Cell (1993) 1.81
Intermediate filament formation by a yeast protein essential for organelle inheritance. Science (1993) 1.75
Thymidine utilization by tut mutants and facile cloning of mutant alleles by plasmid conversion in S. cerevisiae. Genetics (1986) 1.63
Human mitochondria and mitochondrial genome function as a single dynamic cellular unit. J Cell Biol (1994) 1.53
The effect of zygotic bud position on the transmission of mitochondrial genes in Saccharomyces cerevisiae. Mol Gen Genet (1978) 1.47
Computer reconstruction of mitochondria from yeast. Methods Enzymol (1979) 1.30
Kinetic and segregational analysis of mitochondrial DNA recombination in yeast. Plasmid (1987) 1.13
AFG2, an essential gene in yeast, encodes a new member of the Sec18p, Pas1p, Cdc48p, TBP-1 family of putative ATPases. Yeast (1993) 0.99
Bromodeoxyuridine labeling and flow cytometric identification of replicating Saccharomyces cerevisiae cells: lengths of cell cycle phases and population variability at specific cell cycle positions. Biotechnol Prog (1991) 0.96
Replication of bromodeoxyuridylate-substituted mitochondrial DNA in yeast. J Bacteriol (1978) 0.95
New alleles of mgm1: a gene encoding a protein with a GTP-binding domain related to dynamin. Curr Genet (1995) 0.92
Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation. Cell (2000) 13.44
Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A. Nature (1986) 11.35
Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase. Cell (1993) 9.84
Translocation of proteins across the endoplasmic reticulum III. Signal recognition protein (SRP) causes signal sequence-dependent and site-specific arrest of chain elongation that is released by microsomal membranes. J Cell Biol (1981) 8.36
A novel mechanism for regulating activity of a transcription factor that controls the unfolded protein response. Cell (1996) 8.17
Signal recognition particle contains a 7S RNA essential for protein translocation across the endoplasmic reticulum. Nature (1982) 7.80
Translocation of proteins across the endoplasmic reticulum. I. Signal recognition protein (SRP) binds to in-vitro-assembled polysomes synthesizing secretory protein. J Cell Biol (1981) 7.40
Purification of a membrane-associated protein complex required for protein translocation across the endoplasmic reticulum. Proc Natl Acad Sci U S A (1980) 7.17
Preparation of microsomal membranes for cotranslational protein translocation. Methods Enzymol (1983) 6.94
Polarization of chemoattractant receptor signaling during neutrophil chemotaxis. Science (2000) 6.93
In vivo localization of DNA sequences and visualization of large-scale chromatin organization using lac operator/repressor recognition. J Cell Biol (1996) 6.78
Fluorescence microscopy in three dimensions. Methods Cell Biol (1989) 6.70
Protein translocation across the endoplasmic reticulum. Cell (1984) 6.69
The transmembrane kinase Ire1p is a site-specific endonuclease that initiates mRNA splicing in the unfolded protein response. Cell (1997) 6.26
Fluorescence microscopy: reduced photobleaching of rhodamine and fluorescein protein conjugates by n-propyl gallate. Science (1982) 5.92
Ribosome pausing and stacking during translation of a eukaryotic mRNA. EMBO J (1988) 5.61
Oligomerization and phosphorylation of the Ire1p kinase during intracellular signaling from the endoplasmic reticulum to the nucleus. EMBO J (1996) 5.46
Mechanism of protein translocation across the endoplasmic reticulum membrane. Annu Rev Cell Biol (1986) 5.28
Protein translocation across the endoplasmic reticulum. II. Isolation and characterization of the signal recognition particle receptor. J Cell Biol (1982) 5.20
Mitosis in living budding yeast: anaphase A but no metaphase plate. Science (1997) 5.15
Intracellular signaling from the endoplasmic reticulum to the nucleus: the unfolded protein response in yeast and mammals. Curr Opin Cell Biol (2001) 5.08
Interphase chromosomes undergo constrained diffusional motion in living cells. Curr Biol (1997) 5.00
tRNA ligase is required for regulated mRNA splicing in the unfolded protein response. Cell (1996) 4.93
I5M: 3D widefield light microscopy with better than 100 nm axial resolution. J Microsc (1999) 4.84
Translocation of proteins across the endoplasmic reticulum. II. Signal recognition protein (SRP) mediates the selective binding to microsomal membranes of in-vitro-assembled polysomes synthesizing secretory protein. J Cell Biol (1981) 4.80
Perturbation of nuclear architecture by long-distance chromosome interactions. Cell (1996) 4.73
In vitro protein translocation across the yeast endoplasmic reticulum: ATP-dependent posttranslational translocation of the prepro-alpha-factor. Cell (1986) 4.59
Cloning of the human estrogen receptor cDNA. Proc Natl Acad Sci U S A (1985) 4.58
Translocation of proteins across membranes: the signal hypothesis and beyond. Symp Soc Exp Biol (1979) 4.54
Direct evidence of a role for heterochromatin in meiotic chromosome segregation. Cell (1996) 4.53
The chicken oestrogen receptor sequence: homology with v-erbA and the human oestrogen and glucocorticoid receptors. EMBO J (1986) 4.47
The signal recognition particle. Annu Rev Biochem (2001) 4.47
Regulation of ribosome biogenesis by the rapamycin-sensitive TOR-signaling pathway in Saccharomyces cerevisiae. Mol Biol Cell (1999) 4.34
The use of Xenopus egg extracts to study mitotic spindle assembly and function in vitro. Methods Cell Biol (1999) 4.31
Model for signal sequence recognition from amino-acid sequence of 54K subunit of signal recognition particle. Nature (1989) 4.25
Microtubule nucleation by gamma-tubulin-containing rings in the centrosome. Nature (1995) 4.24
Tryptic dissection and reconstitution of translocation activity for nascent presecretory proteins across microsomal membranes. Proc Natl Acad Sci U S A (1979) 4.22
Protein translocation across the endoplasmic reticulum. I. Detection in the microsomal membrane of a receptor for the signal recognition particle. J Cell Biol (1982) 4.10
Chromosome and low copy plasmid segregation in E. coli: visual evidence for distinct mechanisms. Cell (1997) 4.06
Bipolar localization of the replication origin regions of chromosomes in vegetative and sporulating cells of B. subtilis. Cell (1997) 3.97
Early transcription and silencing of cytokine genes underlie polarization of T helper cell subsets. Immunity (2001) 3.84
Three-dimensional architecture of a polytene nucleus. Nature (1983) 3.82
Fragile X premutation is a significant risk factor for premature ovarian failure: the International Collaborative POF in Fragile X study--preliminary data. Am J Med Genet (1999) 3.82
Human papillomavirus type 16 DNA cooperates with activated ras in transforming primary cells. EMBO J (1987) 3.81
Comparison of the in vitro transforming activities of human papillomavirus types. EMBO J (1988) 3.81
Determination of the nucleotide sequence of a fragment of bacteriophage phiX 174 DNA. Nat New Biol (1973) 3.74
An E. coli ribonucleoprotein containing 4.5S RNA resembles mammalian signal recognition particle. Science (1990) 3.55
Photocrosslinking of the signal sequence of nascent preprolactin to the 54-kilodalton polypeptide of the signal recognition particle. Proc Natl Acad Sci U S A (1986) 3.55
Spatial control of actin polymerization during neutrophil chemotaxis. Nat Cell Biol (1999) 3.45
The unfolded protein response coordinates the production of endoplasmic reticulum protein and endoplasmic reticulum membrane. Mol Biol Cell (1997) 3.45
Block of HAC1 mRNA translation by long-range base pairing is released by cytoplasmic splicing upon induction of the unfolded protein response. Cell (2001) 3.45
Disassembly and reconstitution of signal recognition particle. Cell (1983) 3.45
Determination of three-dimensional imaging properties of a light microscope system. Partial confocal behavior in epifluorescence microscopy. Biophys J (1990) 3.44
Signal sequences specify the targeting route to the endoplasmic reticulum membrane. J Cell Biol (1996) 3.33
The signal recognition particle in S. cerevisiae. Cell (1991) 3.24
Structure of the DNA of bacteriophage phiX174. VII. Methylation. J Mol Biol (1970) 3.23
Elongation arrest is not a prerequisite for secretory protein translocation across the microsomal membrane. J Cell Biol (1985) 3.19
Each of the activities of signal recognition particle (SRP) is contained within a distinct domain: analysis of biochemical mutants of SRP. Cell (1988) 3.11
Detection of Babesia microti by polymerase chain reaction. J Clin Microbiol (1992) 3.03
Conservation. Challenges to the future conservation of the Antarctic. Science (2012) 3.01
Time-lapse microscopy reveals unique roles for kinesins during anaphase in budding yeast. J Cell Biol (1998) 2.97
Head injuries in three Scottish neurosurgical units. Scottish head injury management study. Br Med J (1979) 2.93
Signal recognition particle: a ribonucleoprotein required for cotranslational translocation of proteins, isolation and properties. Methods Enzymol (1983) 2.87
Mechanism of non-spliceosomal mRNA splicing in the unfolded protein response pathway. EMBO J (1999) 2.84
Prm1p, a pheromone-regulated multispanning membrane protein, facilitates plasma membrane fusion during yeast mating. J Cell Biol (2000) 2.83
Paths of carbon in gluconeogenesis and lipogenesis: the role of mitochondria in supplying precursors of phosphoenolpyruvate. Proc Natl Acad Sci U S A (1965) 2.81
Dynamics of centromeres during metaphase-anaphase transition in fission yeast: Dis1 is implicated in force balance in metaphase bipolar spindle. Mol Biol Cell (1998) 2.79
Heavy-chain binding protein recognizes aberrant polypeptides translocated in vitro. Nature (1988) 2.78
The unfolded protein response regulates multiple aspects of secretory and membrane protein biogenesis and endoplasmic reticulum quality control. J Cell Biol (2000) 2.71
Protein phosphatase 2A regulates MPF activity and sister chromatid cohesion in budding yeast. Curr Biol (1996) 2.71
Large-scale chromatin structural domains within mitotic and interphase chromosomes in vivo and in vitro. Chromosoma (1989) 2.66
Enteropathogenic E. coli acts through WASP and Arp2/3 complex to form actin pedestals. Nat Cell Biol (1999) 2.65
Block in anaphase chromosome separation caused by a telomerase template mutation. Science (1997) 2.65
Immediate heart-rate response to standing: simple test for autonomic neuropathy in diabetes. Br Med J (1978) 2.65
The use of a charge-coupled device for quantitative optical microscopy of biological structures. Science (1987) 2.64
Dynamics of a chemoattractant receptor in living neutrophils during chemotaxis. Mol Biol Cell (1999) 2.61
Intracellular signaling from the endoplasmic reticulum to the nucleus. Annu Rev Cell Dev Biol (1998) 2.59
Structure of the conserved GTPase domain of the signal recognition particle. Nature (1997) 2.52
Paths of carbon in gluconeogenesis and lipogenesis. 3. The role and regulation of mitochondrial processes involved in supplying precursors of phosphoenolpyruvate. J Biol Chem (1966) 2.49
The unfolded protein response: an intracellular signalling pathway with many surprising features. Trends Cell Biol (1998) 2.48
Studies on intercellular LETS glycoprotein matrices. Cell (1978) 2.44
Crystal structure of the signal sequence binding subunit of the signal recognition particle. Cell (1998) 2.44
Three-dimensional multiple-wavelength fluorescence microscopy for the structural analysis of biological phenomena. Semin Cell Biol (1991) 2.43
Three-dimensional structural characterization of centrosomes from early Drosophila embryos. J Cell Biol (1995) 2.41
Targeting of the hepatitis B virus precore protein to the endoplasmic reticulum membrane: after signal peptide cleavage translocation can be aborted and the product released into the cytoplasm. J Cell Biol (1988) 2.41
Retinal side-effects of sildenafil. Lancet (1999) 2.40
Spatial organization of chromosomes in the salivary gland nuclei of Drosophila melanogaster. J Cell Biol (1986) 2.39
Multiple regimes of constrained chromosome motion are regulated in the interphase Drosophila nucleus. Curr Biol (2001) 2.37
Interaction of E. coli Ffh/4.5S ribonucleoprotein and FtsY mimics that of mammalian signal recognition particle and its receptor. Nature (1994) 2.37
The methionine-rich domain of the 54 kd protein subunit of the signal recognition particle contains an RNA binding site and can be crosslinked to a signal sequence. EMBO J (1990) 2.35
Meiotic chromosome pairing in maize is associated with a novel chromatin organization. Cell (1994) 2.34
Specific interactions of chromatin with the nuclear envelope: positional determination within the nucleus in Drosophila melanogaster. Mol Biol Cell (1996) 2.32
Interphase nuclear envelope lamins form a discontinuous network that interacts with only a fraction of the chromatin in the nuclear periphery. Cell (1990) 2.32
Translational attenuation mediated by an mRNA intron. Curr Biol (1997) 2.32
Human SRP RNA and E. coli 4.5S RNA contain a highly homologous structural domain. Cell (1988) 2.31
A mitochondrial protease with two catalytic subunits of nonoverlapping specificities. Science (1993) 2.28