Published in J Virol on September 01, 1997
Hepatitis C virus-encoded enzymatic activities and conserved RNA elements in the 3' nontranslated region are essential for virus replication in vivo. J Virol (2000) 5.26
Characterization of cell lines carrying self-replicating hepatitis C virus RNAs. J Virol (2001) 4.86
Kissing-loop interaction in the 3' end of the hepatitis C virus genome essential for RNA replication. J Virol (2005) 3.21
De novo initiation of RNA synthesis by the RNA-dependent RNA polymerase (NS5B) of hepatitis C virus. J Virol (2000) 2.65
Translational control of viral gene expression in eukaryotes. Microbiol Mol Biol Rev (2000) 2.63
Genetic analysis of sequences in the 3' nontranslated region of hepatitis C virus that are important for RNA replication. J Virol (2002) 2.62
In vivo analysis of the 3' untranslated region of the hepatitis C virus after in vitro mutagenesis of an infectious cDNA clone. Proc Natl Acad Sci U S A (1999) 2.56
The 3'-untranslated region of hepatitis C virus RNA enhances translation from an internal ribosomal entry site. J Virol (1998) 2.36
A recombinant hepatitis C virus RNA-dependent RNA polymerase capable of copying the full-length viral RNA. J Virol (1999) 2.16
The hepatitis C virus RNA 3'-untranslated region strongly enhances translation directed by the internal ribosome entry site. J Virol (2006) 1.63
A novel diagnostic target in the hepatitis C virus genome. PLoS Med (2009) 1.52
Mutations in the 5' nontranslated region of bovine viral diarrhea virus result in altered growth characteristics. J Virol (2000) 1.51
Dynamics of subgenomic hepatitis C virus replicon RNA levels in Huh-7 cells after exposure to nucleoside antimetabolites. J Virol (2003) 1.39
Sequence and structural elements at the 3' terminus of bovine viral diarrhea virus genomic RNA: functional role during RNA replication. J Virol (1999) 1.38
A long-range RNA-RNA interaction between the 5' and 3' ends of the HCV genome. RNA (2009) 1.34
Hepatitis C virus 3'X region interacts with human ribosomal proteins. J Virol (2001) 1.29
Specific interaction between the hepatitis C virus NS5B RNA polymerase and the 3' end of the viral RNA. J Virol (1999) 1.28
Mov34 protein from mouse brain interacts with the 3' noncoding region of Japanese encephalitis virus. J Virol (2000) 1.14
Chloroplast phosphoglycerate kinase, a gluconeogenetic enzyme, is required for efficient accumulation of Bamboo mosaic virus. Nucleic Acids Res (2006) 1.07
Analysis of hepatitis C virus RNA dimerization and core-RNA interactions. Nucleic Acids Res (2006) 0.99
The FUSE binding protein is a cellular factor required for efficient replication of hepatitis C virus. J Virol (2008) 0.98
Characterization of multimeric complexes formed by the human PTB1 protein on RNA. RNA (2006) 0.96
Secondary structure of the 3' terminus of hepatitis C virus minus-strand RNA. J Virol (2002) 0.94
Identification of a novel sequence at the 3' end of the GB virus B genome. J Virol (1999) 0.93
Template requirements for de novo RNA synthesis by hepatitis C virus nonstructural protein 5B polymerase on the viral X RNA. J Virol (2002) 0.93
Secondary structure and hybridization accessibility of hepatitis C virus 3'-terminal sequences. J Virol (2002) 0.92
Hepatitis C virus RNA: molecular switches mediated by long-range RNA-RNA interactions? Nucleic Acids Res (2012) 0.92
Essential and nonessential elements in the 3' nontranslated region of Bovine viral diarrhea virus. J Virol (2005) 0.90
Structural characterization of the highly conserved 98-base sequence at the 3' end of HCV RNA genome and the complementary sequence located at the 5' end of the replicative viral strand. Nucleic Acids Res (2005) 0.83
Inhibition of HCV replication by oxysterol-binding protein-related protein 4 (ORP4) through interaction with HCV NS5B and alteration of lipid droplet formation. PLoS One (2013) 0.82
Antisense oligonucleotide inhibition of hepatitis C virus genotype 4 replication in HepG2 cells. Cancer Cell Int (2006) 0.81
MEAN inhibits hepatitis C virus replication by interfering with a polypyrimidine tract-binding protein. J Cell Mol Med (2016) 0.75
Immortalized Human Hepatic Cell Lines for In Vitro Testing and Research Purposes. Methods Mol Biol (2015) 0.75
Nuclear Magnetic Resonance Study of RNA Structures at the 3'-End of the Hepatitis C Virus Genome. Biochemistry (2017) 0.75
Genetic organization and diversity of the hepatitis C virus. Proc Natl Acad Sci U S A (1991) 14.05
Molecular cloning of the human hepatitis C virus genome from Japanese patients with non-A, non-B hepatitis. Proc Natl Acad Sci U S A (1990) 9.98
Structure and organization of the hepatitis C virus genome isolated from human carriers. J Virol (1991) 8.33
Cap-independent translation of encephalomyocarditis virus RNA: structural elements of the internal ribosomal entry site and involvement of a cellular 57-kD RNA-binding protein. Genes Dev (1990) 6.64
Distinct binding specificities and functions of higher eukaryotic polypyrimidine tract-binding proteins. Science (1995) 5.97
Identification and properties of the RNA-dependent RNA polymerase of hepatitis C virus. EMBO J (1996) 5.47
A cytoplasmic 57-kDa protein that is required for translation of picornavirus RNA by internal ribosomal entry is identical to the nuclear pyrimidine tract-binding protein. Proc Natl Acad Sci U S A (1993) 4.71
Identification of a highly conserved sequence element at the 3' terminus of hepatitis C virus genome RNA. J Virol (1996) 4.59
Identification and purification of a 62,000-dalton protein that binds specifically to the polypyrimidine tract of introns. Genes Dev (1989) 4.53
Characterization and molecular cloning of polypyrimidine tract-binding protein: a component of a complex necessary for pre-mRNA splicing. Genes Dev (1991) 4.28
hnRNP I, the polypyrimidine tract-binding protein: distinct nuclear localization and association with hnRNAs. Nucleic Acids Res (1992) 3.89
Characterization of cDNAs encoding the polypyrimidine tract-binding protein. Genes Dev (1991) 3.55
Structure of the 3' terminus of the hepatitis C virus genome. J Virol (1996) 3.40
Translation of poliovirus RNA: role of an essential cis-acting oligopyrimidine element within the 5' nontranslated region and involvement of a cellular 57-kilodalton protein. J Virol (1991) 2.86
Biochemical and genetic evidence for a pseudoknot structure at the 3' terminus of the poliovirus RNA genome and its role in viral RNA amplification. J Virol (1993) 2.65
A novel sequence found at the 3' terminus of hepatitis C virus genome. Biochem Biophys Res Commun (1995) 2.58
Molecular cloning of hepatitis C virus genome from a single Japanese carrier: sequence variation within the same individual and among infected individuals. Virus Res (1992) 2.56
Polypyrimidine tract binding protein interacts with sequences involved in alternative splicing of beta-tropomyosin pre-mRNA. J Biol Chem (1992) 2.53
The involvement of a spliceosome component in internal initiation of human rhinovirus RNA translation. J Gen Virol (1993) 2.51
Two proteins crosslinked to RNA containing the adenovirus L3 poly(A) site require the AAUAAA sequence for binding. EMBO J (1988) 2.32
Site-specific interaction of Qbeta host factor and ribosomal protein S1 with Qbeta and R17 bacteriophage RNAs. J Biol Chem (1976) 2.29
Characterization of a host protein associated with brome mosaic virus RNA-dependent RNA polymerase. Proc Natl Acad Sci U S A (1993) 2.22
Genetic organization and diversity of the 3' noncoding region of the hepatitis C virus genome. Virology (1996) 2.04
BHK cell proteins that bind to the 3' stem-loop structure of the West Nile virus genome RNA. J Virol (1995) 1.99
Smooth muscle-specific switching of alpha-tropomyosin mutually exclusive exon selection by specific inhibition of the strong default exon. EMBO J (1994) 1.91
Three different cellular proteins bind to complementary sites on the 5'-end-positive and 3'-end-negative strands of mouse hepatitis virus RNA. J Virol (1993) 1.64
Cellular proteins bind to the 3' end of Sindbis virus minus-strand RNA. J Virol (1992) 1.63
Interaction of polypyrimidine tract binding protein with the encephalomyocarditis virus mRNA internal ribosomal entry site. Biochemistry (1993) 1.53
RNA polymerase II initiation factor alpha from rat liver is almost identical to human TFIIB. Nucleic Acids Res (1992) 1.45
Specific binding of host cell proteins to the 3'-terminal stem-loop structure of rubella virus negative-strand RNA. J Virol (1991) 1.43
Cell type-specific proteins which interact with the 5' nontranslated region of hepatitis A virus RNA. J Virol (1993) 1.40
A conserved motif at the 3' end of mouse hepatitis virus genomic RNA required for host protein binding and viral RNA replication. Virology (1995) 1.36
Pyrimidine tract binding protein strongly stimulates in vitro encephalomyocarditis virus RNA translation at the level of preinitiation complex formation. FEBS Lett (1994) 1.33
RNA-protein interactions directed by the 3' end of human rhinovirus genomic RNA. J Virol (1995) 1.32
Multiple binding sites for cellular proteins in the 3' end of Sindbis alphavirus minus-sense RNA. J Virol (1993) 1.32
Specific binding of host cellular proteins to multiple sites within the 3' end of mouse hepatitis virus genomic RNA. J Virol (1995) 1.29
Cell proteins bind to sites within the 3' noncoding region and the positive-strand leader sequence of measles virus RNA. J Virol (1993) 1.11
RNA-protein interactions at the 3' end of the hepatitis A virus RNA. J Virol (1996) 1.04
Cell proteins bind specifically to West Nile virus minus-strand 3' stem-loop RNA. J Virol (1996) 1.02
Genetic analysis of the hepatitis C virus (HCV) genome from HCV-infected human T cells. J Gen Virol (1997) 0.98
Replication of hepatitis C virus in cultured non-neoplastic human hepatocytes. Jpn J Cancer Res (1996) 0.94
Cell proteins bind to a linear polypyrimidine-rich sequence within the 5'-untranslated region of rhinovirus 14 RNA. J Virol (1995) 0.84
Host factors required for internal initiation of translation on poliovirus RNA. Arch Virol (1994) 0.84
The complete genome sequence of the gram-positive bacterium Bacillus subtilis. Nature (1997) 33.47
Essential Bacillus subtilis genes. Proc Natl Acad Sci U S A (2003) 14.01
Construction of a colicin E1-R factor composite plasmid in vitro: means for amplification of deoxyribonucleic acid. J Bacteriol (1975) 13.95
Infection of HTLV-III/LAV in HTLV-I-carrying cells MT-2 and MT-4 and application in a plaque assay. Science (1985) 10.71
Molecular cloning of the human hepatitis C virus genome from Japanese patients with non-A, non-B hepatitis. Proc Natl Acad Sci U S A (1990) 9.98
Internal ribosome entry site within hepatitis C virus RNA. J Virol (1992) 9.14
Complete nucleotide sequences of all three poliovirus serotype genomes. Implication for genetic relationship, gene function and antigenic determinants. J Mol Biol (1984) 8.06
A protein covalently linked to poliovirus genome RNA. Proc Natl Acad Sci U S A (1977) 7.92
Complete genome sequence of an aerobic hyper-thermophilic crenarchaeon, Aeropyrum pernix K1. DNA Res (1999) 7.39
The 5' end of poliovirus mRNA is not capped with m7G(5')ppp(5')Np. Proc Natl Acad Sci U S A (1976) 7.26
Gene mapping of the putative structural region of the hepatitis C virus genome by in vitro processing analysis. Proc Natl Acad Sci U S A (1991) 7.15
Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality. Proc Natl Acad Sci U S A (1997) 7.08
The nucleotide sequence of pUB110: some salient features in relation to replication and its regulation. Plasmid (1986) 7.07
Ordered recruitment of transcription and chromatin remodeling factors to a cell cycle- and developmentally regulated promoter. Cell (1999) 6.83
Complete sequence and gene organization of the genome of a hyper-thermophilic archaebacterium, Pyrococcus horikoshii OT3. DNA Res (1998) 6.79
Comprehensive analysis of microRNA expression patterns in hepatocellular carcinoma and non-tumorous tissues. Oncogene (2006) 6.61
Essential role of Stat6 in IL-4 signalling. Nature (1996) 6.56
The immune responses in CD40-deficient mice: impaired immunoglobulin class switching and germinal center formation. Immunity (1994) 6.18
Complete nucleotide sequence of the attenuated poliovirus Sabin 1 strain genome. Proc Natl Acad Sci U S A (1982) 6.09
Prevention of second primary tumors by an acyclic retinoid, polyprenoic acid, in patients with hepatocellular carcinoma. Hepatoma Prevention Study Group. N Engl J Med (1996) 6.01
Sequence of retrovirus provirus resembles that of bacterial transposable elements. Nature (1980) 5.95
Typing hepatitis C virus by polymerase chain reaction with type-specific primers: application to clinical surveys and tracing infectious sources. J Gen Virol (1992) 5.93
p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53. Cell (2000) 5.64
The location of the polio genome protein in viral RNAs and its implication for RNA synthesis. Nature (1977) 5.61
A second virus-encoded proteinase involved in proteolytic processing of poliovirus polyprotein. Cell (1986) 5.53
Cohesin's binding to chromosomes depends on a separate complex consisting of Scc2 and Scc4 proteins. Mol Cell (2000) 5.49
The 5'-terminal sequence of the hepatitis C virus genome. Jpn J Exp Med (1990) 5.46
Two distinct proteinase activities required for the processing of a putative nonstructural precursor protein of hepatitis C virus. J Virol (1993) 5.41
Full-length sequence of a hepatitis C virus genome having poor homology to reported isolates: comparative study of four distinct genotypes. Virology (1992) 5.16
Syringe method for stepwise chemical synthesis of oligonucleotides. Nucleic Acids Res (1982) 4.70
O4-(5'-uridylyl)tyrosine is the bond between the genome-linked protein and the RNA of poliovirus. Proc Natl Acad Sci U S A (1978) 4.68
Poliovirus proteinase 2A induces cleavage of eucaryotic initiation factor 4F polypeptide p220. J Virol (1987) 4.52
Norwalk virus infection of volunteers: new insights based on improved assays. J Infect Dis (1994) 4.37
Complete nucleotide sequence of an infectious clone of human T-cell leukemia virus type II: an open reading frame for the protease gene. Proc Natl Acad Sci U S A (1985) 4.28
Identification and characterization of the potential promoter regions of 1031 kinds of human genes. Genome Res (2001) 4.03
The 5'-terminal structures of poliovirion RNA and poliovirus mRNA differ only in the genome-linked protein VPg. Proc Natl Acad Sci U S A (1977) 3.97
Genetic analysis of the attenuation phenotype of poliovirus type 1. J Virol (1986) 3.94
A novel signaling molecule, p130, forms stable complexes in vivo with v-Crk and v-Src in a tyrosine phosphorylation-dependent manner. EMBO J (1994) 3.88
A neomycin resistance gene cassette selectable in a single copy state in the Bacillus subtilis chromosome. Nucleic Acids Res (1989) 3.87
Real-time detection system for quantification of hepatitis C virus genome. Gastroenterology (1999) 3.83
Formation of infectious progeny virus after insertion of herpes simplex thymidine kinase gene into DNA of an avian retrovirus. Cell (1981) 3.80
Construction of viable deletion and insertion mutants of the Sabin strain of type 1 poliovirus: function of the 5' noncoding sequence in viral replication. J Virol (1987) 3.79
Transcriptional sequencing: A method for DNA sequencing using RNA polymerase. Proc Natl Acad Sci U S A (1998) 3.78
High guanine plus cytosine content in the third letter of codons of an extreme thermophile. DNA sequence of the isopropylmalate dehydrogenase of Thermus thermophilus. J Biol Chem (1984) 3.76
An endothelial receptor for oxidized low-density lipoprotein. Nature (1997) 3.76
Calcium-induced conformational transition revealed by the solution structure of apo calmodulin. Nat Struct Biol (1995) 3.75
Mammalian karyopherin alpha 1 beta and alpha 2 beta heterodimers: alpha 1 or alpha 2 subunit binds nuclear localization signal and beta subunit interacts with peptide repeat-containing nucleoporins. Proc Natl Acad Sci U S A (1995) 3.73
Proteolytic processing and membrane association of putative nonstructural proteins of hepatitis C virus. Proc Natl Acad Sci U S A (1993) 3.68
The M1- and M2-type isozymes of rat pyruvate kinase are produced from the same gene by alternative RNA splicing. J Biol Chem (1986) 3.64
Sequence of 3,687 nucleotides from the 3' end of Sendai virus genome RNA and the predicted amino acid sequences of viral NP, P and C proteins. Nucleic Acids Res (1983) 3.62
Requirement of multiple copies of a 21-nucleotide sequence in the U3 regions of human T-cell leukemia virus type I and type II long terminal repeats for trans-acting activation of transcription. Proc Natl Acad Sci U S A (1986) 3.60
IL-12 up-regulates IL-18 receptor expression on T cells, Th1 cells, and B cells: synergism with IL-18 for IFN-gamma production. J Immunol (1998) 3.56
Evidence for in vitro replication of hepatitis C virus genome in a human T-cell line. Proc Natl Acad Sci U S A (1992) 3.55
Nectin/PRR: an immunoglobulin-like cell adhesion molecule recruited to cadherin-based adherens junctions through interaction with Afadin, a PDZ domain-containing protein. J Cell Biol (1999) 3.47
Diverse transcriptional initiation revealed by fine, large-scale mapping of mRNA start sites. EMBO Rep (2001) 3.47
Phosphorylation of hepatitis C virus-encoded nonstructural protein NS5A. J Virol (1995) 3.41
Structure of the 3' terminus of the hepatitis C virus genome. J Virol (1996) 3.40
Identification of the putative transforming protein of the human T-cell leukemia viruses HTLV-I and HTLV-II. Science (1984) 3.39
Microarray fabrication with covalent attachment of DNA using bubble jet technology. Nat Biotechnol (2000) 3.38
Transformation of human leukocytes by cocultivation with an adult T cell leukemia virus producer cell line. Science (1982) 3.37
Molecular mechanics of calcium-myristoyl switches. Nature (1997) 3.36
A prospective randomised study of "covered" versus "uncovered" diamond stents for the management of distal malignant biliary obstruction. Gut (2004) 3.35
The poliovirus receptor protein is produced both as membrane-bound and secreted forms. EMBO J (1990) 3.31
Sequence analysis of hepatitis C virus isolated from a fulminant hepatitis patient. J Med Virol (2001) 3.29
Regulation of the fission yeast transcription factor Pap1 by oxidative stress: requirement for the nuclear export factor Crm1 (Exportin) and the stress-activated MAP kinase Sty1/Spc1. Genes Dev (1998) 3.27
Il-6 and its soluble receptor orchestrate a temporal switch in the pattern of leukocyte recruitment seen during acute inflammation. Immunity (2001) 3.27
Genetic drift of hepatitis C virus during an 8.2-year infection in a chimpanzee: variability and stability. Virology (1992) 3.22
A high-throughput SNP typing system for genome-wide association studies. J Hum Genet (2001) 3.18
Hypervariable regions in the putative glycoprotein of hepatitis C virus. Biochem Biophys Res Commun (1991) 3.09
Size and shape effects in the biodistribution of intravascularly injected particles. J Control Release (2009) 3.08
Identification of the spinocerebellar ataxia type 2 gene using a direct identification of repeat expansion and cloning technique, DIRECT. Nat Genet (1996) 3.07
Altered pain perception and inflammatory response in mice lacking prostacyclin receptor. Nature (1997) 3.07
Neutralizing antibodies against hepatitis C virus and the emergence of neutralization escape mutant viruses. J Virol (1994) 3.06
N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide, a calmodulin antagonist, inhibits cell proliferation. Proc Natl Acad Sci U S A (1981) 3.04
Complete genome sequence of an aerobic thermoacidophilic crenarchaeon, Sulfolobus tokodaii strain7. DNA Res (2001) 2.99
Determinants in the 5' noncoding region of poliovirus Sabin 1 RNA that influence the attenuation phenotype. J Virol (1989) 2.98
Poliovirus polypeptide precursors: expression in vitro and processing by exogenous 3C and 2A proteinases. Proc Natl Acad Sci U S A (1987) 2.98
Cloning of the genes for penicillinase, penP and penI, of Bacillus licheniformis in some vector plasmids and their expression in Escherichia coli, Bacillus subtilis, and Bacillus licheniformis. J Bacteriol (1981) 2.93
Single-molecule analysis of chemotactic signaling in Dictyostelium cells. Science (2001) 2.89
Production of two phosphoproteins from the NS5A region of the hepatitis C viral genome. Biochem Biophys Res Commun (1994) 2.89
Impaired febrile response in mice lacking the prostaglandin E receptor subtype EP3. Nature (1998) 2.88
Transgenic mice susceptible to poliovirus. Proc Natl Acad Sci U S A (1991) 2.87
Regulation of yAP-1 nuclear localization in response to oxidative stress. EMBO J (1997) 2.84
Two human homologues of Saccharomyces cerevisiae SWI2/SNF2 and Drosophila brahma are transcriptional coactivators cooperating with the estrogen receptor and the retinoic acid receptor. Nucleic Acids Res (1994) 2.81
Familial gastrointestinal stromal tumours with germline mutation of the KIT gene. Nat Genet (1998) 2.80
Nature of phosphorus limitation in the ultraoligotrophic eastern Mediterranean. Science (2005) 2.79
The soluble interleukin 6 receptor: mechanisms of production and implications in disease. FASEB J (2001) 2.78
Hepatitis C virus-encoded nonstructural protein NS4A has versatile functions in viral protein processing. J Virol (1995) 2.76
Humoral immune response to hypervariable region 1 of the putative envelope glycoprotein (gp70) of hepatitis C virus. J Virol (1993) 2.74
Finer features for functional microdevices. Nature (2001) 2.73