Published in Mol Cell Biol on September 01, 1997
Mechanisms of hepatic fibrogenesis. Gastroenterology (2008) 11.98
Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver. Physiol Rev (2008) 10.28
The poly(C)-binding proteins: a multiplicity of functions and a search for mechanisms. RNA (2002) 3.62
ELAV proteins stabilize deadenylated intermediates in a novel in vitro mRNA deadenylation/degradation system. Genes Dev (1999) 3.45
Distinct poly(rC) binding protein KH domain determinants for poliovirus translation initiation and viral RNA replication. J Virol (2002) 1.71
Origin of myofibroblasts in the fibrotic liver in mice. Proc Natl Acad Sci U S A (2014) 1.71
Assembly of the alpha-globin mRNA stability complex reflects binary interaction between the pyrimidine-rich 3' untranslated region determinant and poly(C) binding protein alphaCP. Mol Cell Biol (1999) 1.66
Cellular protein modification by poliovirus: the two faces of poly(rC)-binding protein. J Virol (2007) 1.51
Identification of mRNAs associated with alphaCP2-containing RNP complexes. Mol Cell Biol (2003) 1.49
Relaxin inhibits effective collagen deposition by cultured hepatic stellate cells and decreases rat liver fibrosis in vivo. Gut (2001) 1.47
Binding of LARP6 to the conserved 5' stem-loop regulates translation of mRNAs encoding type I collagen. J Mol Biol (2009) 1.30
A nucleolin-binding 3' untranslated region element stabilizes beta-globin mRNA in vivo. Mol Cell Biol (2006) 1.23
Molecular mechanism of hepatic stellate cell activation and antifibrotic therapeutic strategies. J Gastroenterol (2008) 1.23
Multimerization of poly(rC) binding protein 2 is required for translation initiation mediated by a viral IRES. RNA (2004) 1.21
A novel role of vimentin filaments: binding and stabilization of collagen mRNAs. Mol Cell Biol (2011) 1.20
Structure of a construct of a human poly(C)-binding protein containing the first and second KH domains reveals insights into its regulatory mechanisms. J Biol Chem (2008) 1.20
Leptin induces increased alpha2(I) collagen gene expression in cultured rat hepatic stellate cells. J Cell Biochem (2003) 1.19
Depletion of the poly(C)-binding proteins alphaCP1 and alphaCP2 from K562 cells leads to p53-independent induction of cyclin-dependent kinase inhibitor (CDKN1A) and G1 arrest. J Biol Chem (2009) 1.17
Structural and functional analysis of an mRNP complex that mediates the high stability of human beta-globin mRNA. Mol Cell Biol (2001) 1.16
Regulatory role of the conserved stem-loop structure at the 5' end of collagen alpha1(I) mRNA. Mol Cell Biol (1999) 1.16
A novel set of nuclear localization signals determine distributions of the alphaCP RNA-binding proteins. Mol Cell Biol (2003) 1.16
A novel role of RNA helicase A in regulation of translation of type I collagen mRNAs. RNA (2011) 1.13
Characterization of the interaction between alphaCP(2) and the 3'-untranslated region of collagen alpha1(I) mRNA. Nucleic Acids Res (2000) 1.13
Myocardin-related transcription factor-A complexes activate type I collagen expression in lung fibroblasts. J Biol Chem (2011) 1.13
Regulation of CXCL-8 (interleukin-8) induction by double-stranded RNA signaling pathways during hepatitis C virus infection. J Virol (2006) 1.12
In vivo association of the stability control protein alphaCP with actively translating mRNAs. Mol Cell Biol (2003) 1.12
The DNA binding protein BTEB mediates acetaldehyde-induced, jun N-terminal kinase-dependent alphaI(I) collagen gene expression in rat hepatic stellate cells. Mol Cell Biol (2000) 1.08
Novel regulation of type IV collagenase (matrix metalloproteinase-9 and -2) activities by transforming growth factor-beta1 in human prostate cancer cell lines. Mol Biol Cell (1999) 1.07
RNA-binding protein RBMS3 is expressed in activated hepatic stellate cells and liver fibrosis and increases expression of transcription factor Prx1. J Mol Biol (2007) 1.07
Fibrodynamics-elucidation of the mechanisms and sites of liver fibrogenesis. World J Gastroenterol (1999) 1.06
Cell and molecular regulation of endothelin-1 production during hepatic wound healing. Mol Biol Cell (2003) 1.05
Nonmuscle myosin-dependent synthesis of type I collagen. J Mol Biol (2010) 1.04
The cyclin-dependent kinase inhibitor p21 is regulated by RNA-binding protein PCBP4 via mRNA stability. Nucleic Acids Res (2010) 1.03
RNA-binding protein PCBP2 modulates glioma growth by regulating FHL3. J Clin Invest (2013) 1.01
The types of hepatic myofibroblasts contributing to liver fibrosis of different etiologies. Front Pharmacol (2014) 1.01
Regulated alpha-globin mRNA decay is a cytoplasmic event proceeding through 3'-to-5' exosome-dependent decapping. RNA (2002) 1.00
Crystal structure of the third KH domain of human poly(C)-binding protein-2 in complex with a C-rich strand of human telomeric DNA at 1.6 A resolution. Nucleic Acids Res (2007) 0.99
TRAM2 protein interacts with endoplasmic reticulum Ca2+ pump Serca2b and is necessary for collagen type I synthesis. Mol Cell Biol (2004) 0.99
The 5' stem-loop regulates expression of collagen alpha1(I) mRNA in mouse fibroblasts cultured in a three-dimensional matrix. Nucleic Acids Res (2000) 0.98
Targeting a KH-domain protein with RNA decoys. RNA (2002) 0.97
Structure and RNA binding of the third KH domain of poly(C)-binding protein 1. Nucleic Acids Res (2005) 0.96
The 3' untranslated region complex involved in stabilization of human alpha-globin mRNA assembles in the nucleus and serves an independent role as a splice enhancer. Mol Cell Biol (2007) 0.96
All-trans and 9-cis retinoic acid alter rat hepatic stellate cell phenotype differentially. Gut (1999) 0.95
miRNA studies in in vitro and in vivo activated hepatic stellate cells. World J Gastroenterol (2011) 0.94
Protein-RNA tethering: the role of poly(C) binding protein 2 in poliovirus RNA replication. Virology (2008) 0.92
Mutation of the 5'-untranslated region stem-loop structure inhibits α1(I) collagen expression in vivo. J Biol Chem (2010) 0.90
Shared stabilization functions of pyrimidine-rich determinants in the erythroid 15-lipoxygenase and alpha-globin mRNAs. Mol Cell Biol (2006) 0.89
Bioconjugation of oligonucleotides for treating liver fibrosis. Oligonucleotides (2007) 0.88
Contribution of the first K-homology domain of poly(C)-binding protein 1 to its affinity and specificity for C-rich oligonucleotides. Nucleic Acids Res (2012) 0.88
Active stabilization of human endothelial nitric oxide synthase mRNA by hnRNP E1 protects against antisense RNA and microRNAs. Mol Cell Biol (2013) 0.87
Receptor-mediated hepatic uptake of M6P-BSA-conjugated triplex-forming oligonucleotides in rats. Bioconjug Chem (2006) 0.86
Serine-threonine kinase receptor-associated protein (STRAP) regulates translation of type I collagen mRNAs. Mol Cell Biol (2013) 0.85
Fructose modulates GLUT5 mRNA stability in differentiated Caco-2 cells: role of cAMP-signalling pathway and PABP (polyadenylated-binding protein)-interacting protein (Paip) 2. Biochem J (2003) 0.84
Targeting collagen expression in alcoholic liver disease. World J Gastroenterol (2011) 0.83
Tacrolimus (FK506) prevents early stages of ethanol induced hepatic fibrosis by targeting LARP6 dependent mechanism of collagen synthesis. PLoS One (2013) 0.83
PCBP2 siRNA reverses the alcohol-induced pro-fibrogenic effects in hepatic stellate cells. Pharm Res (2011) 0.82
Prevention of liver fibrosis by triple helix-forming oligodeoxyribonucleotides targeted to the promoter region of type I collagen gene. Oligonucleotides (2010) 0.82
Regulation of type I collagen mRNA in lung fibroblasts by cystine availability. Biochem J (1998) 0.82
Incrimination of heterogeneous nuclear ribonucleoprotein E1 (hnRNP-E1) as a candidate sensor of physiological folate deficiency. J Biol Chem (2011) 0.82
Endothelin-1 mediated regulation of extracellular matrix collagens in cells of human lamina cribrosa. Exp Eye Res (2008) 0.82
Withaferin-A reduces type I collagen expression in vitro and inhibits development of myocardial fibrosis in vivo. PLoS One (2012) 0.82
Role of LARP6 and nonmuscle myosin in partitioning of collagen mRNAs to the ER membrane. PLoS One (2014) 0.81
Influence of physiologic folate deficiency on human papillomavirus type 16 (HPV16)-harboring human keratinocytes in vitro and in vivo. J Biol Chem (2012) 0.79
Common variations in noncoding regions of the human natriuretic peptide receptor A gene have quantitative effects. Hum Genet (2002) 0.79
Role of cytokine receptor-like factor 1 in hepatic stellate cells and fibrosis. World J Hepatol (2012) 0.79
Formation of an alphaCP1-KH3 complex with UC-rich RNA. Eur Biophys J (2005) 0.79
Expression and location of Smad2, 4 mRNAs during and after liver fibrogenesis of rats. World J Gastroenterol (2006) 0.78
Norovirus genome circularization and efficient replication are facilitated by binding of PCBP2 and hnRNP A1. J Virol (2013) 0.78
LARP6 Meets Collagen mRNA: Specific Regulation of Type I Collagen Expression. Int J Mol Sci (2016) 0.78
Specific enrichment of the RNA-binding proteins PCBP1 and PCBP2 in chief cells of the murine gastric mucosa. Gene Expr Patterns (2014) 0.77
RNA protein interactions governing expression of the most abundant protein in human body, type I collagen. Wiley Interdiscip Rev RNA (2013) 0.77
Mice deficient in poly(C)-binding protein 4 are susceptible to spontaneous tumors through increased expression of ZFP871 that targets p53 for degradation. Genes Dev (2016) 0.75
Enhanced effect of soluble transforming growth factor-beta receptor II and IFN-gamma fusion protein in reversing hepatic fibrosis. Eur J Med Res (2010) 0.75
mTORC1 phosphorylates LARP6 to stimulate type I collagen expression. Sci Rep (2017) 0.75
Structural determinants of human ζ-globin mRNA stability. J Hematol Oncol (2014) 0.75
Activated hepatic stellate cells play pivotal roles in hepatocellular carcinoma cell chemoresistance and migration in multicellular tumor spheroids. Sci Rep (2016) 0.75
Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem (1987) 281.19
Rapid and efficient site-specific mutagenesis without phenotypic selection. Proc Natl Acad Sci U S A (1985) 68.48
mRNA stability in mammalian cells. Microbiol Rev (1995) 8.78
Degradation of mRNA in eukaryotes. Cell (1995) 6.81
The cap and poly(A) tail function synergistically to regulate mRNA translational efficiency. Genes Dev (1991) 6.03
Hepatic lipocytes: the principal collagen-producing cells of normal rat liver. Proc Natl Acad Sci U S A (1985) 4.76
Characterization and primary structure of the poly(C)-binding heterogeneous nuclear ribonucleoprotein complex K protein. Mol Cell Biol (1992) 3.18
Cell cycle regulation of mouse H3 histone mRNA metabolism. Mol Cell Biol (1984) 2.97
Identification of two KH domain proteins in the alpha-globin mRNP stability complex. EMBO J (1995) 2.87
Transforming growth factor-beta increases steady state levels of type I procollagen and fibronectin messenger RNAs posttranscriptionally in cultured human dermal fibroblasts. J Clin Invest (1987) 2.74
Transforming growth factor beta increases mRNA for matrix proteins both in the presence and in the absence of changes in mRNA stability. Proc Natl Acad Sci U S A (1988) 2.73
Extracellular matrix gene expression increases preferentially in rat lipocytes and sinusoidal endothelial cells during hepatic fibrosis in vivo. J Clin Invest (1990) 2.73
In vitro and in vivo association of transforming growth factor-beta 1 with hepatic fibrosis. J Cell Biol (1989) 2.47
Isolated hepatic lipocytes and Kupffer cells from normal human liver: morphological and functional characteristics in primary culture. Hepatology (1992) 2.40
Detection and characterization of a 3' untranslated region ribonucleoprotein complex associated with human alpha-globin mRNA stability. Mol Cell Biol (1995) 2.36
In situ hybridization for procollagen types I, III and IV mRNA in normal and fibrotic rat liver: evidence for predominant expression in nonparenchymal liver cells. Hepatology (1989) 2.34
Purified rat liver fat-storing cells in culture divide and contain collagen. Hepatology (1984) 2.14
In vitro differentiation of fat-storing cells parallels marked increase of collagen synthesis and secretion. J Hepatol (1989) 2.09
Diversity of cytoplasmic functions for the 3' untranslated region of eukaryotic transcripts. Curr Opin Cell Biol (1995) 2.06
Erythroid cell-specific determinants of alpha-globin mRNA stability. Mol Cell Biol (1994) 1.96
Regulatory elements in the first intron contribute to transcriptional control of the human alpha 1(I) collagen gene. Proc Natl Acad Sci U S A (1987) 1.96
The contraction of hepatic stellate (Ito) cells stimulated with vasoactive substances. Possible involvement of endothelin 1 and nitric oxide in the regulation of the sinusoidal tonus. Eur J Biochem (1993) 1.80
Procollagen expression by nonparenchymal rat liver cells in experimental biliary fibrosis. Gastroenterology (1990) 1.77
Cellular sources of collagen and regulation of collagen production in liver. Semin Liver Dis (1990) 1.71
Common mechanisms for the control of eukaryotic transcriptional elongation. Bioessays (1993) 1.68
Activation-dependent contractility of rat hepatic lipocytes in culture and in vivo. J Clin Invest (1993) 1.63
Regulatory elements in the 5'-flanking region and the first intron contribute to transcriptional control of the mouse alpha 1 type I collagen gene. Mol Cell Biol (1989) 1.55
DNA sequences in the first intron of the human pro-alpha 1(I) collagen gene enhance transcription. J Biol Chem (1987) 1.51
Alcoholic liver injury in baboons: transformation of lipocytes to transitional cells. Gastroenterology (1984) 1.51
Perisinusoidal fat-storing cells are the main vitamin A storage sites in rat liver. Exp Cell Res (1985) 1.37
A conserved nucleotide sequence, coding for a segment of the C-propeptide, is found at the same location in different collagen genes. Nucleic Acids Res (1983) 1.37
An upstream regulatory region mediates high-level, tissue-specific expression of the human alpha 1(I) collagen gene in transgenic mice. Mol Cell Biol (1991) 1.36
Functional analysis of cis-acting DNA sequences controlling transcription of the human type I collagen genes. J Biol Chem (1990) 1.36
Ito-cell gene expression and collagen regulation. Hepatology (1990) 1.32
Tissue specificity of type I collagen gene expression is determined at both transcriptional and post-transcriptional levels. Mol Cell Biol (1984) 1.26
Photoaffinity cross-linking methods for studying RNA-protein interactions. Methods Enzymol (1989) 1.26
Characterization of desmin-positive rat liver sinusoidal cells. Hepatology (1987) 1.23
Transforming growth factor-beta 1 and type I procollagen transcripts during regeneration and early fibrosis of rat liver. Lab Invest (1990) 1.22
Synthesis and degradation of type I procollagen mRNAs in cultured human skin fibroblasts and the effect of cortisol. J Biol Chem (1985) 1.22
Long-range RNA interaction of two sequence elements required for endonucleolytic cleavage of human insulin-like growth factor II mRNAs. Mol Cell Biol (1995) 1.18
Analysis of the collagen alpha 1(I) promoter. Nucleic Acids Res (1989) 1.15
Regulation of the alpha 1(I) collagen promoter in vascular smooth muscle cells. Comparison with other alpha 1(I) collagen-producing cells in transgenic animals and cultured cells. J Biol Chem (1994) 1.14
Transcription factors nuclear factor I and Sp1 interact with the murine collagen alpha 1 (I) promoter. Mol Cell Biol (1991) 1.12
Transcriptional switch from albumin to alpha-fetoprotein and changes in transcription of other genes during carbon tetrachloride induced liver regeneration. Biochemistry (1986) 1.11
Regulation of expression of the type I collagen genes. Am J Med Genet (1993) 1.10
Isolation of a murine gene encoding a nucleic acid-binding protein with homology to hnRNP K. Nucleic Acids Res (1993) 1.07
Acetaldehyde-induced stimulation of collagen synthesis and gene expression is dependent on conditions of cell culture: studies with rat lipocytes and fibroblasts. Alcohol Clin Exp Res (1994) 1.05
Regulation of collagen I gene expression by ras. Mol Cell Biol (1992) 1.03
Sp1 binding activity increases in activated Ito cells. Hepatology (1995) 1.01
DNA methylation represses the murine alpha 1(I) collagen promoter by an indirect mechanism. Mol Cell Biol (1994) 0.99
Transcriptional mechanisms of type I collagen gene expression are differentially regulated by interleukin-1 beta, tumor necrosis factor alpha, and transforming growth factor beta in Ito cells. J Biol Chem (1992) 0.99
Effect of the 3'-untranslated region on the expression levels and mRNA stability of alpha 1(I) collagen gene. Biochim Biophys Acta (1995) 0.99
Tissue-specific expression of the gene for type I procollagen (COL1A1) in transgenic mice. Only 476 base pairs of the promoter are required if collagen genes are used as reporters. J Biol Chem (1995) 0.97
Differential regulation of transcription and transcript stability of pro-alpha 1(I) collagen and fibronectin in activated fibroblasts derived from patients with systemic scleroderma. Biochem J (1996) 0.97
Stimulation of the collagen alpha 1 (I) endogenous gene and transgene in carbon tetrachloride-induced hepatic fibrosis. Hepatology (1993) 0.93
NF-I/Sp1 switch elements regulate collagen alpha 1(I) gene expression. DNA Cell Biol (1992) 0.92
The use of caprylic acid for the extraction of the immunoglobulin fraction from egg yolk of chickens immunised with ovine alpha-lactalbumin. J Immunol Methods (1994) 0.92
Pathogenesis of hepatic fibrosis and the role of cytokines. J Clin Gastroenterol (1992) 0.92
Two different cis-acting regulatory regions direct cell-specific transcription of the collagen alpha 1(I) gene in hepatic stellate cells and in skin and tendon fibroblasts. J Clin Invest (1995) 0.90
Collagen production by rat liver fat-storing cells in primary culture. Exp Cell Biol (1986) 0.90
Human-mouse interspecies collagen I heterotrimer is functional during embryonic development of Mov13 mutant mouse embryos. Mol Cell Biol (1990) 0.90
Changes in albumin, alpha-fetoprotein and collagen gene transcription in CCl4-induced hepatic fibrosis. Hepatology (1988) 0.89
Binding of upstream stimulatory factor to an E-box in the 3'-flanking region stimulates alpha1(I) collagen gene transcription. J Biol Chem (1997) 0.86
Two mRNAs of mouse pro alpha 1(I) collagen gene differ in the size of the 3'-untranslated region. Nucleic Acids Res (1988) 0.85
Nuclear and cytoplasmic alpha 1 (I) collagen mRNA-binding proteins. FEBS Lett (1994) 0.85
The effects of hepatic fibrosis on Ito cell gene expression. Matrix (1992) 0.83
A fibroblast protein binds the 3'-untranslated region of pro-alpha 1(I) collagen mRNA. Biochem J (1993) 0.81
The mitochondrial permeability transition in cell death: a common mechanism in necrosis, apoptosis and autophagy. Biochim Biophys Acta (1998) 4.50
Correlation between liver histology and novel magnetic resonance imaging in adult patients with non-alcoholic fatty liver disease - MRI accurately quantifies hepatic steatosis in NAFLD. Aliment Pharmacol Ther (2012) 3.25
Hepatic stellate cells as a target for the treatment of liver fibrosis. Semin Liver Dis (2001) 2.98
Curcumin blocks cytokine-mediated NF-kappa B activation and proinflammatory gene expression by inhibiting inhibitory factor I-kappa B kinase activity. J Immunol (1999) 2.55
Effect of insertions, deletions, and double-strand breaks on homologous recombination in mouse L cells. Mol Cell Biol (1985) 2.44
The role of TGFbeta1 in initiating hepatic stellate cell activation in vivo. J Hepatol (1999) 2.35
NFkappaB prevents apoptosis and liver dysfunction during liver regeneration. J Clin Invest (1998) 2.27
Inhibition of NFkappaB in activated rat hepatic stellate cells by proteasome inhibitors and an IkappaB super-repressor. Hepatology (1998) 2.18
The focal adhesion kinase suppresses transformation-associated, anchorage-independent apoptosis in human breast cancer cells. Involvement of death receptor-related signaling pathways. J Biol Chem (2000) 2.17
Reperfusion after liver transplantation in rats differentially activates the mitogen-activated protein kinases. Hepatology (1997) 2.14
Tumor necrosis factor alpha stimulates AP-1 activity through prolonged activation of the c-Jun kinase. J Biol Chem (1994) 1.90
Mechanisms of hepatic toxicity. I. TNF-induced liver injury. Am J Physiol (1998) 1.89
The role of Smad3 in mediating mouse hepatic stellate cell activation. Hepatology (2001) 1.88
The enzymatic defect in variegate prophyria. Studies with human cultured skin fibroblasts. N Engl J Med (1980) 1.79
Double-strand gap repair results in homologous recombination in mouse L cells. Proc Natl Acad Sci U S A (1986) 1.72
Mice lacking inducible nitric oxide synthase have improved left ventricular contractile function and reduced apoptotic cell death late after myocardial infarction. Circ Res (2001) 1.70
Oncogenic Ras activates c-Jun via a separate pathway from the activation of extracellular signal-regulated kinases. Proc Natl Acad Sci U S A (1994) 1.67
The mitochondrial permeability transition is required for tumor necrosis factor alpha-mediated apoptosis and cytochrome c release. Mol Cell Biol (1998) 1.66
NF-kappaB inactivation converts a hepatocyte cell line TNF-alpha response from proliferation to apoptosis. Am J Physiol (1998) 1.63
Tumor necrosis factor alpha inhibits collagen gene transcription and collagen synthesis in cultured human fibroblasts. J Biol Chem (1988) 1.58
Alcohol causes both tolerance and sensitization of rat Kupffer cells via mechanisms dependent on endotoxin. Gastroenterology (1998) 1.58
Regulatory elements in the 5'-flanking region and the first intron contribute to transcriptional control of the mouse alpha 1 type I collagen gene. Mol Cell Biol (1989) 1.55
CD40 activates NF-kappa B and c-Jun N-terminal kinase and enhances chemokine secretion on activated human hepatic stellate cells. J Immunol (2001) 1.54
A simplified method for the preparation of transcriptionally active liver nuclear extracts. DNA Cell Biol (1990) 1.53
Stimulation of collagen gene expression by ascorbic acid in cultured human fibroblasts. A role for lipid peroxidation? J Biol Chem (1989) 1.52
Inhibition of proinflammatory molecule production by adenovirus-mediated expression of a nuclear factor kappaB super-repressor in human intestinal epithelial cells. J Immunol (1998) 1.51
Hepatitis C - contamination of toothbrushes: myth or reality? J Viral Hepat (2006) 1.48
Mitochondrial dysfunction in the pathogenesis of necrotic and apoptotic cell death. J Bioenerg Biomembr (1999) 1.46
The mitochondrial permeability transition augments Fas-induced apoptosis in mouse hepatocytes. J Biol Chem (2000) 1.44
Decreasing fibrogenesis: an immunohistochemical study of paired liver biopsies following lamivudine therapy for chronic hepatitis B. J Hepatol (2001) 1.38
TNF-alpha-induced sphingosine 1-phosphate inhibits apoptosis through a phosphatidylinositol 3-kinase/Akt pathway in human hepatocytes. J Immunol (2001) 1.37
L-glutamine stimulates intestinal cell proliferation and activates mitogen-activated protein kinases. Am J Physiol (1997) 1.36
Expression of intracellular adhesion molecule 1 by activated hepatic stellate cells. Hepatology (1996) 1.35
TAK1/JNK and p38 have opposite effects on rat hepatic stellate cells. Hepatology (2001) 1.34
Development of a new, simple rat model of early alcohol-induced liver injury based on sensitization of Kupffer cells. Hepatology (1999) 1.33
Ceramide activates the stress-activated protein kinases. J Biol Chem (1995) 1.33
Tumor necrosis factor-alpha induces c-jun during the regenerative response to liver injury. Am J Physiol (1994) 1.31
Cytokines induce NF-kappaB in activated but not in quiescent rat hepatic stellate cells. Am J Physiol (1998) 1.29
Activation of Jun kinase is an early event in hepatic regeneration. J Clin Invest (1995) 1.28
Association between serum ferritin and the insulin resistance syndrome in a representative population. Eur J Endocrinol (2006) 1.28
Concanavalin A-induced liver cell damage: activation of intracellular pathways triggered by tumor necrosis factor in mice. Gastroenterology (1998) 1.28
Role of Kupffer cells and gut-derived endotoxins in alcoholic liver injury. J Gastroenterol Hepatol (2000) 1.26
Cell therapy attenuates deleterious ventricular remodeling and improves cardiac performance after myocardial infarction. Circulation (2001) 1.25
NF-kappaB stimulates inducible nitric oxide synthase to protect mouse hepatocytes from TNF-alpha- and Fas-mediated apoptosis. Gastroenterology (2001) 1.24
Akt protects mouse hepatocytes from TNF-alpha- and Fas-mediated apoptosis through NK-kappa B activation. Am J Physiol Gastrointest Liver Physiol (2001) 1.23
Nuclear factor kappaB in proliferation, activation, and apoptosis in rat hepatic stellate cells. J Hepatol (2000) 1.23
For IRES trans-acting factors, it is all about location. Oncogene (2007) 1.21
New ways of initiating translation in eukaryotes. Mol Cell Biol (2001) 1.20
Kupffer cell-derived prostaglandin E(2) is involved in alcohol-induced fat accumulation in rat liver. Am J Physiol Gastrointest Liver Physiol (2000) 1.20
The recombination and integration of DNAs introduced into mouse L cells. Cold Spring Harb Symp Quant Biol (1984) 1.19
RNA-binding protein HuR mediates cytoprotection through stimulation of XIAP translation. Oncogene (2010) 1.17
Regulatory role of the conserved stem-loop structure at the 5' end of collagen alpha1(I) mRNA. Mol Cell Biol (1999) 1.16
A fluorometric assay for measurement of protoporphyrinogen oxidase activity in mammalian tissue. Clin Chim Acta (1980) 1.16
Association between novel MRI-estimated pancreatic fat and liver histology-determined steatosis and fibrosis in non-alcoholic fatty liver disease. Aliment Pharmacol Ther (2013) 1.15
Loss of E-cadherin leads to upregulation of NFkappaB activity in malignant melanoma. Oncogene (2004) 1.14
Far upstream regulatory elements enhance position-independent and uterus-specific expression of the murine alpha1(I) collagen promoter in transgenic mice. Gene Expr (1999) 1.14
Characterization of the interaction between alphaCP(2) and the 3'-untranslated region of collagen alpha1(I) mRNA. Nucleic Acids Res (2000) 1.13
Transcription factors nuclear factor I and Sp1 interact with the murine collagen alpha 1 (I) promoter. Mol Cell Biol (1991) 1.12
NF-kappaB inhibits expression of the alpha1(I) collagen gene. DNA Cell Biol (1999) 1.11
Differential expression of human lysyl hydroxylase genes, lysine hydroxylation, and cross-linking of type I collagen during osteoblastic differentiation in vitro. J Bone Miner Res (1999) 1.09
A single promoter directs both housekeeping and erythroid preferential expression of the human ferrochelatase gene. J Biol Chem (1994) 1.09
Study of factors causing excess protoporphyrin accumulation in cultured skin fibroblasts from patients with protoporphyria. J Clin Invest (1977) 1.09
HIV-1 infection and expression in human colonic cells: infection and expression in CD4+ and CD4- cell lines. AIDS (1991) 1.08
IRES in distress: translational regulation of the inhibitor of apoptosis proteins XIAP and HIAP2 during cell stress. Cell Death Differ (2005) 1.05
Analysis of signaling protein kinases in human colon or colorectal carcinomas. Dig Dis Sci (1998) 1.04
Interleukin-6 increases rat metalloproteinase-13 gene expression through stimulation of activator protein 1 transcription factor in cultured fibroblasts. J Biol Chem (1999) 1.04
Estrogen increases sensitivity of hepatic Kupffer cells to endotoxin. Am J Physiol (1998) 1.03
Differential role of I kappa B kinase 1 and 2 in primary rat hepatocytes. Hepatology (2001) 1.02
Celecoxib induces hepatic stellate cell apoptosis through inhibition of Akt activation and suppresses hepatic fibrosis in rats. Gut (2009) 1.01
NF45 functions as an IRES trans-acting factor that is required for translation of cIAP1 during the unfolded protein response. Cell Death Differ (2009) 1.01
Differential effects of deoxycholic acid and taurodeoxycholic acid on NF-kappa B signal transduction and IL-8 gene expression in colonic epithelial cells. Am J Physiol Gastrointest Liver Physiol (2004) 1.01
Sp1 binding activity increases in activated Ito cells. Hepatology (1995) 1.01
d-alpha-tocopherol inhibits collagen alpha 1(I) gene expression in cultured human fibroblasts. Modulation of constitutive collagen gene expression by lipid peroxidation. J Clin Invest (1991) 1.00
Therapeutic strategies for hepatic fibrosis. Hepatology (1988) 1.00
Inactivation of plasmid reporter gene expression by one benzo(a)pyrene diol-epoxide DNA adduct in adult rat hepatocytes. Cancer Res (1993) 1.00
Different effects of a CD14 gene polymorphism on disease outcome in patients with alcoholic liver disease and chronic hepatitis C infection. World J Gastroenterol (2005) 0.99
DNA methylation represses the murine alpha 1(I) collagen promoter by an indirect mechanism. Mol Cell Biol (1994) 0.99
Identification of c-fos-responsive elements downstream of TAR in the long terminal repeat of human immunodeficiency virus type-1. J Clin Invest (1993) 0.99
Transient induction of c-jun during hepatic regeneration. Hepatology (1990) 0.99
The 5' stem-loop regulates expression of collagen alpha1(I) mRNA in mouse fibroblasts cultured in a three-dimensional matrix. Nucleic Acids Res (2000) 0.98
DNA-mediated gene transfer into adult rat hepatocytes in primary culture. Mol Cell Biol (1990) 0.98
The CAAX peptidomimetic compound B581 specifically blocks farnesylated, but not geranylgeranylated or myristylated, oncogenic ras signaling and transformation. J Biol Chem (1994) 0.97
TNF receptor-associated factor-2 is involved in both IL-1 beta and TNF-alpha signaling cascades leading to NF-kappa B activation and IL-8 expression in human intestinal epithelial cells. J Immunol (1999) 0.97
Hepatic stellate cells display a functional vascular smooth muscle cell phenotype in a three-dimensional co-culture model with endothelial cells. Differentiation (2008) 0.97
In vivo activation of mitogen-activated protein kinases in rat intestinal neoplasia. Gastroenterology (1997) 0.96
hnRNP A1 regulates UV-induced NF-kappaB signalling through destabilization of cIAP1 mRNA. Cell Death Differ (2008) 0.96
Autocrine expression of activated transforming growth factor-beta(1) induces apoptosis in normal rat liver. Am J Physiol Gastrointest Liver Physiol (2001) 0.96
Long-term alcohol exposure changes sensitivity of rat Kupffer cells to lipopolysaccharide. Alcohol Clin Exp Res (2001) 0.95
Confocal microscopy of the mitochondrial permeability transition in necrotic cell killing, apoptosis and autophagy. Biofactors (1998) 0.93
Expression of augmenter of liver regeneration (ALR) in human liver cirrhosis and carcinoma. Histopathology (2005) 0.93
Pronase destroys the lipopolysaccharide receptor CD14 on Kupffer cells. Am J Physiol (1999) 0.93
Glutamine metabolism stimulates intestinal cell MAPKs by a cAMP-inhibitable, Raf-independent mechanism. Gastroenterology (2000) 0.92
NF-I/Sp1 switch elements regulate collagen alpha 1(I) gene expression. DNA Cell Biol (1992) 0.92