S M Roberts

Author PubWeight™ 86.66‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Yeast Gcn5 functions in two multisubunit complexes to acetylate nucleosomal histones: characterization of an Ada complex and the SAGA (Spt/Ada) complex. Genes Dev 1997 8.35
2 Functional organization of the yeast SAGA complex: distinct components involved in structural integrity, nucleosome acetylation, and TATA-binding protein interaction. Mol Cell Biol 1999 3.90
3 The Saccharomyces cerevisiae SPT8 gene encodes a very acidic protein that is functionally related to SPT3 and TATA-binding protein. Genetics 1994 2.04
4 Pharmacological and biochemical analysis of FPL 67156, a novel, selective inhibitor of ecto-ATPase. Br J Pharmacol 1995 1.57
5 Prognostic factors and survival of horses with ocular/adnexal squamous cell carcinoma: 147 cases (1978-1988). J Am Vet Med Assoc 1991 1.32
6 Epidemiologic study of ocular/adnexal squamous cell carcinoma in horses. J Am Vet Med Assoc 1991 1.29
7 Improving the primary management of emergency surgical admissions: a controlled trial. Ann R Coll Surg Engl 1995 1.16
8 Evaluation of methods for producing renal dysfunction in rats. J Pharm Sci 1981 1.13
9 Structure of human factor VIIa and its implications for the triggering of blood coagulation. Proc Natl Acad Sci U S A 1999 1.12
10 Recent advances in the use of enzyme-catalysed reactions in organic research: the synthesis of biologically active natural products and analogues. Nat Prod Rep 1986 1.06
11 Effect of ophthalmic prednisolone acetate on the canine adrenal gland and hepatic function. Am J Vet Res 1984 1.03
12 Correlation between glutathione oxidation and trimerization of heat shock factor 1, an early step in stress induction of the Hsp response. Cell Stress Chaperones 1998 1.03
13 The synthesis of new adenosine A3 selective ligands containing bioisosteric isoxazoles. Bioorg Med Chem Lett 1998 1.02
14 Comparison of PCR, virus isolation, and indirect fluorescent antibody staining in the detection of naturally occurring feline herpesvirus infections. J Vet Diagn Invest 1999 1.01
15 Soil ingestion: a concern for acute toxicity in children. Environ Health Perspect 1997 1.00
16 Tegument surface membranes of adult Schistosoma mansoni: development of a method for their isolation. Mol Biochem Parasitol 1983 0.96
17 Lacerations of the equine eye: a review of 48 cases. J Am Vet Med Assoc 1984 0.95
18 Regional enteritis of the duodenum. Radiology 1966 0.95
19 Effect of N-acetylcysteine on heat shock protein induction by acetaminophen in mouse liver. J Pharmacol Exp Ther 1998 0.93
20 Protection against hepatotoxicity by a single dose of amphetamine: the potential role of heat shock protein induction. Toxicol Appl Pharmacol 1997 0.92
21 Radiation-induced ocular injury in the dog: a histological study. Int J Radiat Oncol Biol Phys 1990 0.91
22 Motoric responses to sucrose in postmature and term infants. Physiol Behav 1997 0.91
23 Synthesis, antimalarial activity, biomimetic iron(II) chemistry, and in vivo metabolism of novel, potent C-10-phenoxy derivatives of dihydroartemisinin. J Med Chem 2001 0.91
24 Polychlorinated biphenyl exposure and human disease. J Occup Med 1993 0.90
25 Comparison of three antismoking interventions among pregnant women in an urban setting: a randomized trial. Psychol Rep 1991 0.89
26 Liver toxicity from norcocaine nitroxide, an N-oxidative metabolite of cocaine. J Pharmacol Exp Ther 1998 0.89
27 Utilizing the health belief model to predict dieting and exercising behavior of obese and nonobese adolescents. Health Educ Q 1985 0.88
28 A review of the papers on the ocular toxicity of ethambutol hydrochloride (myambutol), an anti-tuberculosis drug. Am J Optom Physiol Opt 1974 0.88
29 Immunodiagnosis of leptospiral uveitis in two horses. Equine Vet J 1987 0.87
30 Ophthalmic complications following megavoltage irradiation of the nasal and paranasal cavities in dogs. J Am Vet Med Assoc 1987 0.86
31 The formation of procainamide hydroxylamine by rat and human liver microsomes. Drug Metab Dispos 1987 0.86
32 Effects of cocaine and its oxidative metabolites on mitochondrial respiration and generation of reactive oxygen species. Biochem Pharmacol 2000 0.86
33 Crystallization and preliminary X-ray diffraction study of a chimaeric Fab' fragment of antibody binding tumour cells. J Mol Biol 1991 0.86
34 Use of orbital implants after enucleation in dogs, horses, and cats: 161 cases (1980-1990). J Am Vet Med Assoc 1993 0.85
35 Genetic, immunologic and biotransformation studies of patients on procainamide. Lupus 1993 0.85
36 The effect of nedocromil sodium on the isolated rabbit vagus nerve. Eur J Pharmacol 1992 0.84
37 BCG treatment of periocular sarcoid. Equine Vet J 1985 0.84
38 Ocular manifestations of Rocky Mountain spotted fever in dogs. J Am Vet Med Assoc 1989 0.84
39 Immunomodulatory effects of procainamide metabolites: their implications in drug-related lupus. J Lab Clin Med 1989 0.83
40 Risk factors for development of chronic superficial keratitis in dogs. J Am Vet Med Assoc 1994 0.83
41 Induction of hsp 70 in HepG2 cells in response to hepatotoxicants. Toxicol Appl Pharmacol 1996 0.83
42 Identification of exposed components on the surface of adult Schistosoma mansoni by lactoperoxidase-catalysed iodination. Mol Biochem Parasitol 1983 0.83
43 Ocular cosmetic and prosthetic devices. Vet Clin North Am Equine Pract 1992 0.82
44 Determination of metabolically derived nitroprocainamide in the urine of procainamide-dosed humans and rats by liquid chromatography with electrochemical detection. Drug Metab Dispos 1991 0.82
45 The pharmacokinetics of 2,2',5,5'-tetrachlorobiphenyl and 3,3',4,4'-tetrachlorobiphenyl and its relationship to toxicity. Toxicol Appl Pharmacol 1989 0.82
46 Novel aliphatic epoxide hydrolase activities from dematiaceous fungi. FEMS Microbiol Lett 1996 0.81
47 Ascorbic acid determination with an automated enzymatic procedure. Clin Chem 1997 0.81
48 Development of a diabetes locus of control scale. Psychol Rep 1987 0.81
49 Crystal structure of a chimeric Fab' fragment of an antibody binding tumour cells. J Mol Biol 1992 0.81
50 Total synthesis of prostaglandin-F2 alpha involving stereocontrolled and photo-induced reactions of bicyclo[3.20]heptanones. J Chem Soc Perkin 1 1980 0.81
51 Assessing mercury health effects in gold workers near El Callao, Venezuela. J Occup Environ Med 2001 0.81
52 Differential heat shock protein induction by acetaminophen and a nonhepatotoxic regioisomer, 3'-hydroxyacetanilide, in mouse liver. J Pharmacol Exp Ther 1997 0.81
53 Enzyme-catalysed kinetic resolution of 4-endo-hydroxy-2-oxabicyclo[3.3.0]oct-7-en-3-one and employment of the pure enantiomers for the synthesis of anti-viral and hypocholestemic agents. Bioorg Med Chem 1994 0.81
54 Reevaluating cancer risk estimates for short-term exposure scenarios. Toxicol Sci 2000 0.81
55 The synthesis of (R)-(+)-lipoic acid using a monooxygenase-catalysed biotransformation as the key step. Bioorg Med Chem 1997 0.81
56 A centrally-mediated effect of morphine to diminish hepatocellular glutathione. Biochem Pharmacol 1987 0.80
57 PaaSiCats: novel polyamino acid catalysts. Chirality 2000 0.80
58 Structure of Fab hGR-2 F6, a competitive antagonist of the glucagon receptor. Acta Crystallogr D Biol Crystallogr 2000 0.80
59 Clinical and histologic evaluation of the prolapsed third eyelid gland in dogs. J Am Vet Med Assoc 1992 0.80
60 Evaluation of results for Schirmer tear tests conducted with and without application of a topical anesthetic in clinically normal dogs of 5 breeds. Am J Vet Res 2000 0.80
61 Depression of hepatic glutathione by opioid analgesic drugs in mice. Toxicol Appl Pharmacol 1989 0.79
62 Detection of Toxoplasma gondii antigen-containing immune complexes in the serum of cats. Am J Vet Res 1993 0.79
63 Ocular manifestations of diabetes mellitus: diabetic cataracts in dogs. Vet Clin North Am Small Anim Pract 1995 0.79
64 Antibacterial activity of dilute povidone-iodine solutions used for ocular surface disinfection in dogs. Am J Vet Res 1986 0.79
65 Pharmacokinetic studies of propoxyphene IV: Effect of renal failure on systemic clearance in rats. J Pharm Sci 1980 0.79
66 Examination of the role of catecholamines in hepatic glutathione suppression by cold-restraint in mice. Toxicology 1991 0.78
67 Heat shock protein induction in murine liver after acute treatment with cocaine. Hepatology 1997 0.78
68 Antagonism of cocaine-induced hepatotoxicity by the alpha adrenergic antagonists phentolamine and yohimbine. J Pharmacol Exp Ther 1987 0.78
69 Low-dose oral administration of interferon-alpha for the treatment of immune-mediated keratoconjunctivitis sicca in dogs. J Interferon Cytokine Res 1999 0.78
70 Utility of the PRECEDE model in differentiating users and nonusers of smokeless tobacco. J Sch Health 1991 0.78
71 Enzyme-linked immunosorbent assays for the detection of Toxoplasma gondii-specific antibodies and antigens in the aqueous humor of cats. J Am Vet Med Assoc 1992 0.78
72 Cocaine hepatotoxicity: influence of hepatic enzyme inducing and inhibiting agents on the site of necrosis. Hepatology 1992 0.78
73 Immunochemical comparison of 3'-hydroxyacetanilide and acetaminophen binding in mouse liver. Drug Metab Dispos 1998 0.78
74 Comparison of gonioscopy and ultrasound biomicroscopy for evaluating the iridocorneal angle in dogs. J Am Vet Med Assoc 1998 0.78
75 Solid-phase synthesis of oligodeoxynucleotides containing 3'-S-phosphorothiolate linkages. Nucleosides Nucleotides Nucleic Acids 2001 0.77
76 The perturbation of hepatic glutathione by alpha 2-adrenergic agonists. Fundam Appl Toxicol 1983 0.77
77 Antagonism of bromobenzene-induced hepatotoxicity by the alpha-adrenergic blocking agents, phentolamine and idazoxan. Toxicol Appl Pharmacol 1988 0.77
78 An assay for phentolamine using high performance liquid chromatography with electrochemical detection. Anal Biochem 1988 0.77
79 Effects of procainamide hydroxylamine on generation of reactive oxygen species by macrophages and production of cytokines. Int J Immunopharmacol 1990 0.77
80 Study of procainamide hapten-specific antibodies in rabbits and humans. Int J Immunopharmacol 1993 0.77
81 Antagonism of bromobenzene-induced hepatotoxicity by phentolamine: evidence for a metabolism-independent intervention. Toxicol Appl Pharmacol 1988 0.76
82 Polyamino acids as catalysts in asymmetric synthesis. Bioorg Med Chem 1999 0.76
83 Phenylpropanolamine potentiation of acetaminophen-induced hepatotoxicity: evidence for a glutathione-dependent mechanism. Toxicol Appl Pharmacol 1993 0.76
84 Monoclonal aggregating immunoglobulin cryoglobulinaemia in a horse with malignant lymphoma. Equine Vet J 1985 0.76
85 Hepatic glutathione suppression by the alpha-adrenoreceptor stimulating agents phenylephrine and clonidine. Toxicology 1991 0.76
86 Antagonism of bromobenzene-induced hepatotoxicity by the alpha-adrenoreceptor blocking agents phentolamine and idazoxan: role of hypothermia. Toxicol Appl Pharmacol 1989 0.76
87 Fluoro carbocyclic nucleosides: synthesis and antiviral activity of 2'- and 6'-fluoro carbocyclic pyrimidine nucleosides including carbocyclic 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-methyluracil and carbocyclic 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-iodouracil. J Med Chem 1990 0.76
88 Massive intoxication with acetaminophen and propoxyphene: unexpected survival and unusual pharmacokinetics of acetaminophen. J Toxicol Clin Toxicol 1982 0.76
89 Modification of hepatic microsomal oxidative drug metabolism in rats by the opiate maintenance drugs acetylmethadol, propoxyphene, and methadone. Life Sci 1979 0.76
90 The EPC approach to estimating safety from exposure to environmental chemicals. Regul Toxicol Pharmacol 1994 0.75
91 Synthesis and biological activity of lactones en route to Altohyrtin A. Bioorg Med Chem Lett 1998 0.75
92 Modified nucleoside 5'-triphosphonates as a new type of antiviral agents. Nucleosides Nucleotides 1999 0.75
93 Fluorocarbocyclic nucleosides: synthesis and antiviral activity of 2'- and 6'-fluorocarbocyclic 2'-deoxy guanosines. J Med Chem 1991 0.75
94 beta-peptides as catalysts: poly-beta-leucine as a catalyst for the Juliá-Colonna asymmetric epoxidation of enones. Chem Commun (Camb) 2001 0.75
95 A retrospective assessment of the long range effects of the fifth and sixth grade units of the school health curriculum project. Health Educ 1990 0.75
96 Influence of soil half-life on risk assessment of carcinogens. Regul Toxicol Pharmacol 1995 0.75
97 Pharmacokinetics of pentoxifylline in dogs after oral and intravenous administration. Am J Vet Res 2000 0.75
98 Depression of glutathione by cold-restraint in mice. Toxicology 1990 0.75
99 Comparison of covalent binding from halothane metabolism in hepatic microsomes from phenobarbital-induced and hyperthyroid rats. Xenobiotica 1988 0.75
100 Centrally mediated opioid induced depression of hepatic glutathione: effects of intracerebroventricular administration of mu, kappa, sigma and delta agonists. Toxicology 1988 0.75
101 Synthetic chemistry. Combating cholesterol. Nature 1995 0.75
102 Diazotised [125I]iodosulphanilic acid is not a marker for the outer bilayer of the tegument of adult Schistosoma mansoni. Mol Biochem Parasitol 1988 0.75
103 Immunochemical detection of hepatic cocaine-protein adducts in mice. Chem Res Toxicol 1998 0.75
104 Effects of piperonyl butoxide on halothane hepatotoxicity and metabolism in the hyperthyroid rat. Toxicology 1988 0.75
105 The effect of the primary structure of the polypeptide catalyst on the enantioselectivity of the Juliá-Colonna asymmetric epoxidation of enones. Chem Commun (Camb) 2001 0.75
106 Systemic osmotherapy for ophthalmic disease in dogs and cats. J Am Vet Med Assoc 1989 0.75
107 Total synthesis of prostaglandin-E2 by rearrangement of a 6,8-disubstituted-2-oxabicyclo[3.2.1]octan-3-one to a 4,5 disubstituted-perhydrocyclopenta[b]furan-2-one. J Chem Soc Perkin 1 1979 0.75
108 Microbial hydrolysis of glutaronitrile derivatives with Brevibacterium sp. R 312. Bioorg Med Chem 1994 0.75
109 Effects of chronic oral methadone on hepatic microsomal drug metabolism in monkeys. Toxicol Appl Pharmacol 1977 0.75
110 Prevalence and treatment of palpebral neoplasms in the dog: 200 cases (1975-1983). J Am Vet Med Assoc 1986 0.75
111 Utility of the modified Health Belief Model in predicting compliance with treatment by adult patients with advanced cancer. Psychol Rep 1986 0.75
112 Recent advances in the generation of chiral intermediates using enzymes. Crit Rev Biotechnol 1990 0.75
113 Demand. J Am Med Womens Assoc 1967 0.75
114 Procainamide acetylation in strains of rat and mouse. Drug Metab Dispos 1985 0.75
115 Histamine and hepatic glutathione in the mouse. Life Sci 1987 0.75
116 Enzyme-controlled reactions giving alkanols of use in the synthesis of biologically active molecules. Ciba Found Symp 1985 0.75
117 Current concepts in equine ocular therapeutics. Vet Clin North Am Large Anim Pract 1984 0.75
118 Perturbation of glutathione by a central action of morphine. Toxicology 1989 0.75
119 Efficient asymmetric epoxidation of alpha,beta-unsaturated ketones using a soluble triblock polyethylene glycol-polyamino acid catalyst. Org Lett 2001 0.75
120 Comparison of human and mouse liver microsomal metabolism of bromobenzene and chlorobenzene to 2- and 4-halophenols. Drug Metab Dispos 1989 0.75
121 Synthesis of prostacyclin derivatives and their analogs. Adv Prostaglandin Thromboxane Leukot Res 1983 0.75