Introduction of a neurotrophin-3 transgene into muscle selectively rescues proprioceptive neurons in mice lacking endogenous neurotrophin-3.

PubWeight™: 1.12‹?› | Rank: Top 10%

🔗 View Article (PMID 9331344)

Published in Neuron on September 01, 1997

Authors

D E Wright1, L Zhou, J Kucera, W D Snider

Author Affiliations

1: Center for the Study of Nervous System Injury, Department of Neurology, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

Articles citing this

Functionally reduced sensorimotor connections form with normal specificity despite abnormal muscle spindle development: the role of spindle-derived neurotrophin 3. J Neurosci (2009) 1.84

Drosophila neurotrophins reveal a common mechanism for nervous system formation. PLoS Biol (2008) 1.43

Long-distance retrograde neurotrophic factor signalling in neurons. Nat Rev Neurosci (2013) 1.30

The TrkC receptor induces apoptosis when the dependence receptor notion meets the neurotrophin paradigm. Proc Natl Acad Sci U S A (2007) 1.26

Neurotrophins and synaptic plasticity in the mammalian spinal cord. J Physiol (2001) 1.15

Expressing TrkC from the TrkA locus causes a subset of dorsal root ganglia neurons to switch fate. Nat Neurosci (2004) 1.07

A chemoattractant role for NT-3 in proprioceptive axon guidance. PLoS Biol (2004) 1.03

Prenatal exposure to elevated NT3 disrupts synaptic selectivity in the spinal cord. J Neurosci (2007) 0.99

Motor neuron trophic factors: therapeutic use in ALS? Brain Res Rev (2010) 0.98

SAD kinases sculpt axonal arbors of sensory neurons through long- and short-term responses to neurotrophin signals. Neuron (2013) 0.95

A new role for neurotrophin-3: involvement in the regulation of hair follicle regression (catagen). Am J Pathol (1998) 0.94

Aerobic exercise alters analgesia and neurotrophin-3 synthesis in an animal model of chronic widespread pain. Phys Ther (2010) 0.90

The recent understanding of the neurotrophin's role in skeletal muscle adaptation. J Biomed Biotechnol (2011) 0.86

Neurotrophin-3 ameliorates sensory-motor deficits in Er81-deficient mice. Dev Dyn (2006) 0.81

Enhancing proprioceptive input to motoneurons differentially affects expression of neurotrophin 3 and brain-derived neurotrophic factor in rat hoffmann-reflex circuitry. PLoS One (2013) 0.78

Neuronal development: SAD kinases make happy axons. Curr Biol (2013) 0.77

Long-term exercise-specific neuroprotection in spinal muscular atrophy-like mice. J Physiol (2016) 0.76

Analysis of Proprioceptive Sensory Innervation of the Mouse Soleus: A Whole-Mount Muscle Approach. PLoS One (2017) 0.75

Role of primary afferents in the developmental regulation of motor axon synapse numbers on Renshaw cells. J Comp Neurol (2016) 0.75

NT-3 promotes proprioceptive axon regeneration when combined with activation of the mTor intrinsic growth pathway but not with reduction of myelin extrinsic inhibitors. Exp Neurol (2016) 0.75

Articles by these authors

Complete genome sequence of the methanogenic archaeon, Methanococcus jannaschii. Science (1996) 41.35

The complete genome sequence of the gastric pathogen Helicobacter pylori. Nature (1997) 34.00

The complete genome sequence of the hyperthermophilic, sulphate-reducing archaeon Archaeoglobus fulgidus. Nature (1997) 14.38

Highly parallel SNP genotyping. Cold Spring Harb Symp Quant Biol (2003) 9.10

Neurological complications of acquired immune deficiency syndrome: analysis of 50 patients. Ann Neurol (1983) 5.98

Construction of coliphage lambda Charon vectors with BamHI cloning sites. Gene (1980) 5.83

Hexokinase as a sugar sensor in higher plants. Plant Cell (1997) 4.89

Use of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia (APL): II. Clinical efficacy and pharmacokinetics in relapsed patients. Blood (1997) 4.78

Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury. Nat Genet (1996) 4.77

BAX is required for neuronal death after trophic factor deprivation and during development. Neuron (1996) 4.02

The role of shared receptor motifs and common Stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15. Immunity (1995) 3.99

Chromosome 2 sequence of the human malaria parasite Plasmodium falciparum. Science (1998) 3.83

Analysis of Arabidopsis glucose insensitive mutants, gin5 and gin6, reveals a central role of the plant hormone ABA in the regulation of plant vegetative development by sugar. Genes Dev (2000) 3.42

The laminin alpha chains: expression, developmental transitions, and chromosomal locations of alpha1-5, identification of heterotrimeric laminins 8-11, and cloning of a novel alpha3 isoform. J Cell Biol (1997) 3.34

IB4-binding DRG neurons switch from NGF to GDNF dependence in early postnatal life. Neuron (1997) 3.21

Missense mutations abolishing DNA binding of the osteoblast-specific transcription factor OSF2/CBFA1 in cleidocranial dysplasia. Nat Genet (1997) 3.20

Incidence, risk factors, and outcomes of osteonecrosis of the jaw: integrated analysis from three blinded active-controlled phase III trials in cancer patients with bone metastases. Ann Oncol (2011) 3.07

Development of sensory neurons in the absence of NGF/TrkA signaling in vivo. Neuron (2000) 3.01

The Brn-3 family of POU-domain factors: primary structure, binding specificity, and expression in subsets of retinal ganglion cells and somatosensory neurons. J Neurosci (1995) 2.94

AML1-ETO expression is directly involved in the development of acute myeloid leukemia in the presence of additional mutations. Proc Natl Acad Sci U S A (2001) 2.84

Widespread elimination of naturally occurring neuronal death in Bax-deficient mice. J Neurosci (1998) 2.80

Lack of neurotrophin-3 leads to deficiencies in the peripheral nervous system and loss of limb proprioceptive afferents. Cell (1994) 2.65

Sugars as signaling molecules. Curr Opin Plant Biol (1999) 2.62

Disruption of the neurotrophin-3 receptor gene trkC eliminates la muscle afferents and results in abnormal movements. Nature (1994) 2.61

Crystal structure of the conserved core of protein arginine methyltransferase PRMT3. EMBO J (2000) 2.56

Physiological role of Akt in insulin-stimulated translocation of GLUT4 in transfected rat adipose cells. Mol Endocrinol (1997) 2.51

POU domain factor Brn-3b is required for the development of a large set of retinal ganglion cells. Proc Natl Acad Sci U S A (1996) 2.48

A family of positive regulators related to the Pseudomonas putida TOL plasmid XylS and the Escherichia coli AraC activators. Nucleic Acids Res (1990) 2.48

Carbon and nitrogen sensing and signaling in plants: emerging 'matrix effects'. Curr Opin Plant Biol (2001) 2.37

Vertebrate slit, a secreted ligand for the transmembrane protein roundabout, is a repellent for olfactory bulb axons. Cell (1999) 2.35

GFR alpha1-deficient mice have deficits in the enteric nervous system and kidneys. Neuron (1998) 2.29

Restricted expression of G86R Cu/Zn superoxide dismutase in astrocytes results in astrocytosis but does not cause motoneuron degeneration. J Neurosci (2000) 2.27

Culture, risk factors and suicide in rural China: a psychological autopsy case control study. Acta Psychiatr Scand (2004) 2.24

Gene targeting reveals a critical role for neurturin in the development and maintenance of enteric, sensory, and parasympathetic neurons. Neuron (1999) 2.22

Mutagenesis of the N-(deoxyguanosin-8-yl)-2-amino-1-methyl-6-phenylimidazo[4, 5-b]pyridine DNA adduct in mammalian cells. Sequence context effects. J Biol Chem (1999) 2.17

Studies on treatment of acute promyelocytic leukemia with arsenic trioxide: remission induction, follow-up, and molecular monitoring in 11 newly diagnosed and 47 relapsed acute promyelocytic leukemia patients. Blood (1999) 2.08

A large carbon sink in the woody biomass of Northern forests. Proc Natl Acad Sci U S A (2001) 2.02

Competence for genetic transformation in Streptococcus pneumoniae: organization of a regulatory locus with homology to two lactococcin A secretion genes. Gene (1995) 1.94

Diet, physical activity, and colorectal cancer among Chinese in North America and China. J Natl Cancer Inst (1990) 1.92

Analysis of the role of AML1-ETO in leukemogenesis, using an inducible transgenic mouse model. Blood (2000) 1.91

Brn-3b: a POU domain gene expressed in a subset of retinal ganglion cells. Neuron (1993) 1.88

Essential role of POU-domain factor Brn-3c in auditory and vestibular hair cell development. Proc Natl Acad Sci U S A (1997) 1.88

The mouse SLIT family: secreted ligands for ROBO expressed in patterns that suggest a role in morphogenesis and axon guidance. Dev Biol (1999) 1.87

Structure of human DNMT2, an enigmatic DNA methyltransferase homolog that displays denaturant-resistant binding to DNA. Nucleic Acids Res (2001) 1.81

PPARgamma activation induces the expression of the adipocyte fatty acid binding protein gene in human monocytes. Biochem Biophys Res Commun (1999) 1.76

Heterodimers of placenta growth factor/vascular endothelial growth factor. Endothelial activity, tumor cell expression, and high affinity binding to Flk-1/KDR. J Biol Chem (1996) 1.75

Safety of extended treatment with anakinra in patients with rheumatoid arthritis. Ann Rheum Dis (2006) 1.74

The pattern of disulfide linkages in the extracellular loop regions of connexin 32 suggests a model for the docking interface of gap junctions. J Cell Biol (1998) 1.73

CBFA1 mutation analysis and functional correlation with phenotypic variability in cleidocranial dysplasia. Hum Mol Genet (1999) 1.72

Sex steroids and bone mass in older men. Positive associations with serum estrogens and negative associations with androgens. J Clin Invest (1997) 1.72

Targeted deletion of the mouse POU domain gene Brn-3a causes selective loss of neurons in the brainstem and trigeminal ganglion, uncoordinated limb movement, and impaired suckling. Proc Natl Acad Sci U S A (1996) 1.71

CUL-2 is required for the G1-to-S-phase transition and mitotic chromosome condensation in Caenorhabditis elegans. Nat Cell Biol (1999) 1.69

Brain-derived neurotrophic factor rescues spinal motor neurons from axotomy-induced cell death. Nature (1993) 1.64

The quaking I-5 protein (QKI-5) has a novel nuclear localization signal and shuttles between the nucleus and the cytoplasm. J Biol Chem (1999) 1.59

Different signaling pathways mediate regenerative versus developmental sensory axon growth. J Neurosci (2001) 1.55

P(0) glycoprotein overexpression causes congenital hypomyelination of peripheral nerves. J Cell Biol (2000) 1.55

Neurotrophin receptor genes are expressed in distinct patterns in developing dorsal root ganglia. J Neurosci (1993) 1.54

Biological consequences of thrombin receptor deficiency in mice. Thromb Haemost (1996) 1.53

Neurotrophins support the development of diverse sensory axon morphologies. J Neurosci (1999) 1.50

Comparison of the TOX A/B test to a cell culture cytotoxicity assay for the detection of Clostridium difficile in stools. Diagn Microbiol Infect Dis (2000) 1.49

Serotonin 5-HT(2C) receptors regulate anxiety-like behavior. Genes Brain Behav (2007) 1.48

Construction and analysis of compact muscle-specific promoters for AAV vectors. Gene Ther (2008) 1.48

Dichotomy of AML1-ETO functions: growth arrest versus block of differentiation. Mol Cell Biol (2001) 1.46

Simultaneous stochastic sensing of divalent metal ions. Nat Biotechnol (2000) 1.44

Heart rhythm disorders and pacemakers: Pulmonary vein isolation combined with substrate modification for persistent atrial fibrillation treatment in patients with valvular heart diseases. Heart (2009) 1.44

Translation and psychometric evaluation of a Chinese version of the SF-36 Health Survey in the United States. J Clin Epidemiol (1998) 1.44

Galectin-1 prolongs survival of mouse liver allografts from Flt3L-pretreated donors. Am J Transplant (2013) 1.44

Cellular and molecular guidance of GABAergic neuronal migration from an extracortical origin to the neocortex. Neuron (1999) 1.44

Initial trajectories of sensory axons toward laminar targets in the developing mouse spinal cord. J Comp Neurol (1997) 1.42

Trophic regulation of nerve cell morphology and innervation in the autonomic nervous system. Nature (1988) 1.41

PDGF A-chain gene is expressed by mammalian neurons during development and in maturity. Cell (1991) 1.41

The immunogenicity, safety, and efficacy of etanercept liquid administered once weekly in patients with rheumatoid arthritis. Clin Exp Rheumatol (2007) 1.41

Neurotrophin receptor mRNA expression defines distinct populations of neurons in rat dorsal root ganglia. J Comp Neurol (1995) 1.40

Imbalance between T helper type 17 and T regulatory cells in patients with primary biliary cirrhosis: the serum cytokine profile and peripheral cell population. Clin Exp Immunol (2009) 1.40

Parameters from preoperative overnight oximetry predict postoperative adverse events. Minerva Anestesiol (2014) 1.39

[Experimental study on decoctum Agrimonia pilosa Ledeb-induced apoptosis in HL-60 cells in vitro]. Zhong Yao Cai (2000) 1.39

Identification and cloning of a granule autoantigen (carboxypeptidase-H) associated with type I diabetes. J Clin Endocrinol Metab (1991) 1.39

Comparison of dietary habits, physical activity and body size among Chinese in North America and China. Int J Epidemiol (1994) 1.37

Polymorphisms of the DNA repair gene XRCC1 and risk of gastric cancer in a Chinese population. Int J Cancer (2000) 1.37

Sustained durability and tolerability of etanercept in ankylosing spondylitis for 96 weeks. Ann Rheum Dis (2005) 1.35

Plant-derived bioactive compounds produced by endophytic fungi. Mini Rev Med Chem (2011) 1.35

Synchronous onset of NGF and TrkA survival dependence in developing dorsal root ganglia. J Neurosci (1996) 1.35

Hyperinnervation of neuromuscular junctions caused by GDNF overexpression in muscle. Science (1998) 1.32

Arthroscopic microdiscectomy and selective fragmentectomy. Clin Orthop Relat Res (1998) 1.32

Mixed modelling to characterize genotype-phenotype associations. Stat Med (2005) 1.31

Presence or absence of TrkA protein distinguishes subsets of small sensory neurons with unique cytochemical characteristics and dorsal horn projections. J Comp Neurol (1995) 1.31

Selective dependence of mammalian dorsal root ganglion neurons on nerve growth factor during embryonic development. Neuron (1992) 1.30

The von Hippel-Lindau tumor suppressor protein regulates gene expression and tumor growth through histone demethylase JARID1C. Oncogene (2011) 1.30

Bcl-xL is an antiapoptotic regulator for postnatal CNS neurons. J Neurosci (1998) 1.29

The transcription factor Egr3 modulates sensory axon-myotube interactions during muscle spindle morphogenesis. Dev Biol (2001) 1.29

Reduced rates of skeletal remodeling are associated with increased bone mineral density during the development of peak skeletal mass. J Bone Miner Res (1997) 1.29

Mice deficient in the candidate tumor suppressor gene Hic1 exhibit developmental defects of structures affected in the Miller-Dieker syndrome. Hum Mol Genet (2000) 1.26

Myelinating Schwann cells determine the internodal localization of Kv1.1, Kv1.2, Kvbeta2, and Caspr. J Neurocytol (2000) 1.26

From mitochondrial dynamics to arrhythmias. Int J Biochem Cell Biol (2009) 1.26

Arsenic trioxide-induced apoptosis and differentiation are associated respectively with mitochondrial transmembrane potential collapse and retinoic acid signaling pathways in acute promyelocytic leukemia. Leukemia (2000) 1.26

Neuralized functions as an E3 ubiquitin ligase during Drosophila development. Curr Biol (2001) 1.24

Nerve growth factor receptor TrkA is down-regulated during postnatal development by a subset of dorsal root ganglion neurons. J Comp Neurol (1997) 1.22

Rate and type of congenital anomalies among offspring of diabetic women. J Reprod Med (1971) 1.21

[The campomelic syndrome]. Presse Med (1971) 1.21