Published in Nature on October 30, 1997
Mapping Wnt/beta-catenin signaling during mouse development and in colorectal tumors. Proc Natl Acad Sci U S A (2003) 7.60
Deciphering the function of canonical Wnt signals in development and disease: conditional loss- and gain-of-function mutations of beta-catenin in mice. Genes Dev (2008) 4.38
Two members of the Tcf family implicated in Wnt/beta-catenin signaling during embryogenesis in the mouse. Mol Cell Biol (1998) 3.09
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Multistep signaling requirements for pituitary organogenesis in vivo. Genes Dev (1998) 2.02
Wnt signaling plays an essential role in neuronal specification of the dorsal spinal cord. Genes Dev (2002) 2.01
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Coordinated activation of Wnt in epithelial and melanocyte stem cells initiates pigmented hair regeneration. Cell (2011) 1.92
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Modulation of mouse neural crest cell motility by N-cadherin and connexin 43 gap junctions. J Cell Biol (2001) 1.38
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Dynamic expression of Lgr5, a Wnt target gene, in the developing and mature mouse cochlea. J Assoc Res Otolaryngol (2011) 1.27
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Vital elements of the Wnt-Frizzled signaling pathway in the nervous system. Curr Neurovasc Res (2005) 1.21
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WNT signaling increases proliferation and impairs differentiation of stem cells in the developing cerebellum. Development (2012) 1.12
The mouse Ovol2 gene is required for cranial neural tube development. Dev Biol (2006) 1.11
Wnt signaling in skin development, homeostasis, and disease. Cold Spring Harb Perspect Biol (2013) 1.11
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Apoptosis in neural crest cells by functional loss of APC tumor suppressor gene. Proc Natl Acad Sci U S A (2001) 1.10
Brn-2 expression controls melanoma proliferation and is directly regulated by beta-catenin. Mol Cell Biol (2004) 1.09
Canonical Wnt signaling is required for ophthalmic trigeminal placode cell fate determination and maintenance. Dev Biol (2007) 1.08
Fgf8a induces neural crest indirectly through the activation of Wnt8 in the paraxial mesoderm. Development (2008) 1.08
Wnt2 expression and signaling is increased by different classes of antidepressant treatments. Biol Psychiatry (2010) 1.07
Hindbrain-derived Wnt and Fgf signals cooperate to specify the otic placode in Xenopus. Dev Biol (2008) 1.06
Dynamic alterations in gene expression after Wnt-mediated induction of avian neural crest. Mol Biol Cell (2005) 1.03
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Anteriorization of neural fate by inhibitor of beta-catenin and T cell factor (ICAT), a negative regulator of Wnt signaling. Proc Natl Acad Sci U S A (2004) 1.02
Triple play: promoting neurovascular longevity with nicotinamide, WNT, and erythropoietin in diabetes mellitus. Biomed Pharmacother (2008) 1.02
Dlx proteins position the neural plate border and determine adjacent cell fates. Development (2003) 1.01
The functions and possible significance of Kremen as the gatekeeper of Wnt signalling in development and pathology. J Cell Mol Med (2007) 1.01
Wnt signaling in vertebrate neural development and function. J Neuroimmune Pharmacol (2012) 1.00
Loss of Wnt8b has no overt effect on hippocampus development but leads to altered Wnt gene expression levels in dorsomedial telencephalon. Dev Dyn (2010) 1.00
Wnt to build a tube: contributions of Wnt signaling to epithelial tubulogenesis. Dev Dyn (2010) 1.00
Cardiac outflow tract septation failure in Pax3-deficient embryos is due to p53-dependent regulation of migrating cardiac neural crest. Mech Dev (2008) 0.99
Pax3 is essential for normal cardiac neural crest morphogenesis but is not required during migration nor outflow tract septation. Dev Biol (2011) 0.99
A network of heterochronic genes including Imp1 regulates temporal changes in stem cell properties. Elife (2013) 0.99
Manipulating gene activity in Wnt1-expressing precursors of neural epithelial and neural crest cells. Dev Dyn (2010) 0.99
Conditional expression of the TVA receptor allows clonal analysis of descendents from Cre-expressing progenitor cells. Dev Biol (2011) 0.98
Derivation of cranial neural crest-like cells from human embryonic stem cells. Biochem Biophys Res Commun (2008) 0.97
G-protein-coupled receptors and melanoma. Pigment Cell Melanoma Res (2008) 0.97
Ror1-Ror2 complexes modulate synapse formation in hippocampal neurons. Neuroscience (2009) 0.95
Palate morphogenesis: current understanding and future directions. Birth Defects Res C Embryo Today (2010) 0.94
WNT2 regulates DNA synthesis in mouse granulosa cells through beta-catenin. Biol Reprod (2010) 0.93
Cloning and developmental expression of mouse pygopus 2, a putative Wnt signaling component. Genomics (2004) 0.93
Cardiac outflow tract anomalies. Wiley Interdiscip Rev Dev Biol (2013) 0.92
Complex and dynamic patterns of Wnt pathway gene expression in the developing chick forebrain. Neural Dev (2009) 0.92
Identification of Wnt-responsive cells in the zebrafish hypothalamus. Zebrafish (2009) 0.92
Wnt1 expression temporally allocates upper rhombic lip progenitors and defines their terminal cell fate in the cerebellum. Mol Cell Neurosci (2011) 0.91
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Wntless in Wnt secretion: molecular, cellular and genetic aspects. Front Biol (Beijing) (2012) 0.89
Differential expression of extracellular matrix-mediated pathways in single-suture craniosynostosis. PLoS One (2011) 0.89
Multiple Wnts redundantly control polarity orientation in Caenorhabditis elegans epithelial stem cells. PLoS Genet (2011) 0.89
Specification of neural crest into sensory neuron and melanocyte lineages. Dev Biol (2012) 0.88
Anti-inflammatory activity of Wnt signaling in enteric nervous system: in vitro preliminary evidences in rat primary cultures. J Neuroinflammation (2015) 0.88
Revising the embryonic origin of thyroid C cells in mice and humans. Development (2015) 0.88
Ovo1 links Wnt signaling with N-cadherin localization during neural crest migration. Development (2010) 0.88
Melanocytes, melanocyte stem cells, and melanoma stem cells. Clin Dermatol (2013) 0.87
Wnt-signaling and senescence: A tug of war in early neoplasia? Cancer Biol Ther (2008) 0.87
Vangl-dependent planar cell polarity signalling is not required for neural crest migration in mammals. Development (2014) 0.87
Hh and Wnt signaling regulate formation of olig2+ neurons in the zebrafish cerebellum. Dev Biol (2008) 0.87
A novel genetic mechanism regulates dorsolateral hinge-point formation during zebrafish cranial neurulation. J Cell Sci (2009) 0.87
Daam2 is required for dorsal patterning via modulation of canonical Wnt signaling in the developing spinal cord. Dev Cell (2012) 0.86
Cochleovestibular nerve development is integrated with migratory neural crest cells. Dev Biol (2013) 0.86
Frizzled3 is required for neurogenesis and target innervation during sympathetic nervous system development. J Neurosci (2011) 0.86
Wnt signaling potentiates nevogenesis. Proc Natl Acad Sci U S A (2013) 0.86
Wnt/beta-catenin signaling in cerebral cortical development. Organogenesis (2008) 0.85
Developmental pathways activated in melanocytes and melanoma. Arch Biochem Biophys (2014) 0.84
Wnt ligand expression in malignant melanoma: pilot study indicating correlation with histopathological features. Mol Pathol (2003) 0.84
Recycling signals in the neural crest. J Biol (2005) 0.83
The complete genome sequence of the gram-positive bacterium Bacillus subtilis. Nature (1997) 33.47
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Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase. Curr Biol (1998) 10.58
Inactivation of the beta-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development. Development (2001) 9.00
Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation. Genes Dev (1999) 8.43
Fate of the mammalian cranial neural crest during tooth and mandibular morphogenesis. Development (2000) 8.07
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Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4. Nature (1994) 6.57
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Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway. Mol Cell (2001) 5.19
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Essential function of Wnt-4 in mammary gland development downstream of progesterone signaling. Genes Dev (2000) 3.30
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