Published in Br J Pharmacol on November 01, 1997
Reactive nitrogen species scavenging, rather than nitric oxide inhibition, protects from articular cartilage damage in rat zymosan-induced arthritis. Br J Pharmacol (2003) 0.87
Protein nitration in cutaneous inflammation in the rat: essential role of inducible nitric oxide synthase and polymorphonuclear leukocytes. Br J Pharmacol (2002) 0.83
Oxygen toxicity, oxygen radicals, transition metals and disease. Biochem J (1984) 13.20
Role of free radicals and catalytic metal ions in human disease: an overview. Methods Enzymol (1990) 11.00
Calcitonin gene-related peptide is a potent vasodilator. Nature (1985) 6.13
Damage to DNA by reactive oxygen and nitrogen species: role in inflammatory disease and progression to cancer. Biochem J (1996) 5.14
The antioxidant action of N-acetylcysteine: its reaction with hydrogen peroxide, hydroxyl radical, superoxide, and hypochlorous acid. Free Radic Biol Med (1989) 5.10
Oxygen free radicals and iron in relation to biology and medicine: some problems and concepts. Arch Biochem Biophys (1986) 4.67
Oxygen radicals and human disease. Ann Intern Med (1987) 4.57
The psychosocial etiology of adolescent drug use: a family interactional approach. Genet Soc Gen Psychol Monogr (1990) 4.49
Formation of nitric oxide-derived inflammatory oxidants by myeloperoxidase in neutrophils. Nature (1998) 4.34
Formation of thiobarbituric-acid-reactive substance from deoxyribose in the presence of iron salts: the role of superoxide and hydroxyl radicals. FEBS Lett (1981) 3.92
Glutathione and ascorbic acid in spinach (Spinacia oleracea) chloroplasts. The effect of hydrogen peroxide and of Paraquat. Biochem J (1983) 3.82
Neutrophils in development of multiple organ failure in sepsis. Lancet (2006) 3.64
The presence of glutathione and glutathione reductase in chloroplasts: A proposed role in ascorbic acid metabolism. Planta (1976) 3.52
Superoxide-dependent formation of hydroxyl radicals in the presence of iron chelates: is it a mechanism for hydroxyl radical production in biochemical systems? FEBS Lett (1978) 3.14
The measurement and mechanism of lipid peroxidation in biological systems. Trends Biochem Sci (1990) 2.86
L-NG-monomethyl arginine and L-NG-nitro arginine inhibit non-adrenergic, non-cholinergic relaxation of the mouse anococcygeus muscle. Br J Pharmacol (1990) 2.84
Inhibition of the iron-catalysed formation of hydroxyl radicals from superoxide and of lipid peroxidation by desferrioxamine. Biochem J (1979) 2.82
The importance of free radicals and catalytic metal ions in human diseases. Mol Aspects Med (1985) 2.79
Superoxide-dependent formation of hydroxyl radicals in the presence of iron salts. Detection of 'free' iron in biological systems by using bleomycin-dependent degradation of DNA. Biochem J (1981) 2.68
Lipid peroxidation, oxygen radicals, cell damage, and antioxidant therapy. Lancet (1984) 2.53
The Concise Guide to PHARMACOLOGY 2013/14: overview. Br J Pharmacol (2013) 2.48
Formation of reactive nitrogen species during peroxidase-catalyzed oxidation of nitrite. A potential additional mechanism of nitric oxide-dependent toxicity. J Biol Chem (1997) 2.48
Free radicals and antioxidants in the year 2000. A historical look to the future. Ann N Y Acad Sci (2000) 2.47
The importance of iron in rheumatoid disease. Lancet (1981) 2.44
Inflammatory oedema induced by synergism between calcitonin gene-related peptide (CGRP) and mediators of increased vascular permeability. Br J Pharmacol (1985) 2.38
Evidence for nitric oxide-mediated oxidative damage in chronic inflammation. Nitrotyrosine in serum and synovial fluid from rheumatoid patients. FEBS Lett (1994) 2.38
Intramitochondrial localisation of glycine decarboxylase in spinach leaves. Biochem Biophys Res Commun (1977) 2.34
Incidence, natural history and cardiovascular events in symptomatic and asymptomatic peripheral arterial disease in the general population. Int J Epidemiol (1996) 2.25
The risks for late adolescence of early adolescent marijuana use. Am J Public Health (1999) 2.17
Oxidative DNA damage in the parkinsonian brain: an apparent selective increase in 8-hydroxyguanine levels in substantia nigra. J Neurochem (1997) 2.10
Subcellular localisation and identification of superoxide dismutase in the leaves of higher plants. Eur J Biochem (1978) 2.09
The smooth muscle relaxant effect of hydrogen sulphide in vitro: evidence for a physiological role to control intestinal contractility. Br J Pharmacol (2002) 2.05
Failure of the ubiquitin-proteasome system in Parkinson's disease. Nat Rev Neurosci (2001) 2.04
Progressive multifocal leukoencephalopathy in patients with HIV infection. J Neurovirol (1998) 2.02
Antioxidant protection against hypochlorous acid in human plasma. J Lab Clin Med (1993) 1.95
Antioxidant actions of thymol, carvacrol, 6-gingerol, zingerone and hydroxytyrosol. Food Chem Toxicol (1994) 1.95
Selective inhibitors of neuronal nitric oxide synthase--is no NOS really good NOS for the nervous system? Trends Pharmacol Sci (1997) 1.92
Superoxide-dependent formation of hydroxyl radicals in the presence of iron salts. Its role in degradation of hyaluronic acid by a superoxide-generating system. FEBS Lett (1978) 1.91
Inhibition of lipid peroxidation by the iron-binding protein lactoferrin. Biochem J (1981) 1.85
The chloroplast at work. A review of modern developments in our understanding of chloroplast metabolism. Prog Biophys Mol Biol (1978) 1.84
Putative biological roles of hydrogen sulfide in health and disease: a breath of not so fresh air? Trends Pharmacol Sci (2008) 1.84
A generalised increase in protein carbonyls in the brain in Parkinson's but not incidental Lewy body disease. J Neurochem (1997) 1.83
Superoxide-dependent formation of hydroxyl radicals: detection of hydroxyl radicals by the hydroxylation of aromatic compounds. Anal Biochem (1981) 1.82
Formation of nitrating and chlorinating species by reaction of nitrite with hypochlorous acid. A novel mechanism for nitric oxide-mediated protein modification. J Biol Chem (1996) 1.78
The measurement of free radical reactions in humans. Some thoughts for future experimentation. FEBS Lett (1987) 1.77
Iron ion-dependent modification of bases in DNA by the superoxide radical-generating system hypoxanthine/xanthine oxidase. J Biol Chem (1989) 1.77
Young adult drug use and delinquency: childhood antecedents and adolescent mediators. J Am Acad Child Adolesc Psychiatry (1996) 1.73
Superoxide-dependent formation of hydroxyl radicals and lipid peroxidation in the presence of iron salts. Detection of 'catalytic' iron and anti-oxidant activity in extracellular fluids. Biochem J (1982) 1.72
Nitric oxide and oxygen radicals: a question of balance. FEBS Lett (1995) 1.70
Regulation of vascular nitric oxide in vitro and in vivo; a new role for endogenous hydrogen sulphide? Br J Pharmacol (2006) 1.68
Biochemical mechanisms accounting for the toxic action of oxygen on living organisms: the key role of superoxide dismutase. Cell Biol Int Rep (1978) 1.68
Copper-ion-dependent damage to the bases in DNA in the presence of hydrogen peroxide. Biochem J (1991) 1.68
Potent vasodilator activity of calcitonin gene-related peptide in human skin. J Invest Dermatol (1986) 1.68
Superoxide-dependent and ascorbate-dependent formation of hydroxyl radicals from hydrogen peroxide in the presence of iron. Are lactoferrin and transferrin promoters of hydroxyl-radical generation? Biochem J (1987) 1.67
Oxidation of formate by peroxisomes and mitochondria from spinach leaves. Biochem J (1974) 1.62
Lipid peroxidation in rheumatoid arthritis: thiobarbituric acid-reactive material and catalytic iron salts in synovial fluid from rheumatoid patients. Clin Sci (Lond) (1984) 1.61
Endothelium-derived relaxing factor and the effects of acetylcholine and histamine on resistance blood vessels. Br J Pharmacol (1988) 1.59
The identification of hydroxy fatty acids in psoriatic skin. Prostaglandins (1983) 1.59
Oxidation of biologic molecules by ozone: the effect of pH. J Lab Clin Med (1993) 1.58
The role of superoxide and hydroxyl radicals in the degradation of hyaluronic acid induced by metal ions and by ascorbic acid. J Inorg Biochem (1981) 1.58
Production of superoxide, hydrogen peroxide and hydroxyl radicals by phagocytic cells: a cause of chronic inflammatory disease? Cell Biol Int Rep (1982) 1.57
Time course of inhibition of brain nitric oxide synthase by 7-nitro indazole. Neuroreport (1994) 1.56
Aldehyde-induced protein modifications in human plasma: protection by glutathione and dihydrolipoic acid. J Lab Clin Med (1994) 1.56
Non-transferrin-bound iron in plasma or serum from patients with idiopathic hemochromatosis. Characterization by high performance liquid chromatography and nuclear magnetic resonance spectroscopy. J Biol Chem (1989) 1.54
Psoriasis and leukotriene B4. Lancet (1982) 1.54
Oxidants, antioxidants, and respiratory tract lining fluids. Environ Health Perspect (1994) 1.53
Effect of a specific iron chelating agent on animal models of inflammation. Ann Rheum Dis (1983) 1.52
Artifacts in cell culture: rapid generation of hydrogen peroxide on addition of (-)-epigallocatechin, (-)-epigallocatechin gallate, (+)-catechin, and quercetin to commonly used cell culture media. Biochem Biophys Res Commun (2000) 1.51
Methods for the measurement of hydroxyl radicals in biomedical systems: deoxyribose degradation and aromatic hydroxylation. Methods Biochem Anal (1988) 1.50
Aromatic hydroxylation as a potential measure of hydroxyl-radical formation in vivo. Identification of hydroxylated derivatives of salicylate in human body fluids. Biochem J (1986) 1.50
Properties of freshly purified and thiol-treated spinach chloroplast fructose bisphosphatase. Biochem J (1980) 1.49
Formation of hydroxyl radicals from hydrogen peroxide in the presence of iron. Is haemoglobin a biological Fenton reagent? Biochem J (1988) 1.49
Supplementation with vitamin C and N-acetyl-cysteine increases oxidative stress in humans after an acute muscle injury induced by eccentric exercise. Free Radic Biol Med (2001) 1.48
Protection against superoxide and hydrogen peroxide in synovial fluid from rheumatoid patients. Clin Sci (Lond) (1981) 1.48
Analysis of free and protein-bound nitrotyrosine in human plasma by a gas chromatography/mass spectrometry method that avoids nitration artifacts. Biochem J (2000) 1.48
The scavenging of oxidants by sulphasalazine and its metabolites. A possible contribution to their anti-inflammatory effects? Biochem Pharmacol (1987) 1.47
Sulphasalazine is a potent inhibitor of prostaglandin 15-hydroxydehydrogenase: possible basis for therapeutic action in ulcerative colitis. Br J Pharmacol (1978) 1.47
Inhibition of rat cerebellar nitric oxide synthase by 7-nitro indazole and related substituted indazoles. Br J Pharmacol (1993) 1.47
Micronutrients: oxidant/antioxidant status. Br J Nutr (2001) 1.47
Tyrosine modification by reactive nitrogen species: a closer look. Arch Biochem Biophys (1995) 1.45
Evidence that endogenous nitric oxide modulates oedema formation induced by substance P. Eur J Pharmacol (1990) 1.45
Antioxidant and pro-oxidant properties of active rosemary constituents: carnosol and carnosic acid. Xenobiotica (1992) 1.44
Action of calcium ions on spinach (Spinacia oleracea) chloroplast fructose bisphosphatase and other enzymes of the Calvin cycle. Biochem J (1980) 1.41
A comparison of the effects of L-NAME, 7-NI and L-NIL on carrageenan-induced hindpaw oedema and NOS activity. Br J Pharmacol (1998) 1.41
Ascorbic acid, metal ions and the superoxide radical. Biochem J (1976) 1.40
Pathways of prostaglandin F2alpha metabolism in mammalian kidneys. Br J Pharmacol (1977) 1.40
Effect of hydrogen peroxide on spinach (Spinacia oleracea) chloroplast fructose bisphosphatase. Biochem J (1980) 1.39
The in vitro cytotoxicity of ascorbate depends on the culture medium used to perform the assay and involves hydrogen peroxide. Antioxid Redox Signal (2001) 1.39
Dietary antioxidants and cigarette smoke-induced biomolecular damage: a complex interaction. Am J Clin Nutr (1995) 1.39
Pathways to marijuana use among adolescents: cultural/ecological, family, peer, and personality influences. J Am Acad Child Adolesc Psychiatry (1998) 1.39
Oxidative decarboxylation of glycollate and glyoxylate by leaf peroxisomes. Biochem J (1974) 1.39
Measurement of allantoin and uric acid in human body fluids. A potential index of free-radical reactions in vivo? Biochem J (1987) 1.39
Antioxidant activity of vitamin C in iron-overloaded human plasma. J Biol Chem (1997) 1.38
Aluminium salts accelerate peroxidation of membrane lipids stimulated by iron salts. Biochim Biophys Acta (1985) 1.37
An assessment of oxidative damage to proteins, lipids, and DNA in brain from patients with Alzheimer's disease. J Neurochem (1997) 1.36
Damage to the bases in DNA induced by hydrogen peroxide and ferric ion chelates. J Biol Chem (1989) 1.35
The gastrointestinal tract: a major site of antioxidant action? Free Radic Res (2000) 1.35
Blood radicals: reactive nitrogen species, reactive oxygen species, transition metal ions, and the vascular system. Pharm Res (1996) 1.35