Published in J Rheumatol on January 01, 1998
B cells in Sjögren's syndrome: indications for disturbed selection and differentiation in ectopic lymphoid tissue. Arthritis Res Ther (2007) 1.16
Advances in understanding the pathogenesis of primary Sjögren's syndrome. Nat Rev Rheumatol (2013) 1.16
NCR3/NKp30 contributes to pathogenesis in primary Sjogren's syndrome. Sci Transl Med (2013) 1.12
Disturbance of cytokine networks in Sjögren's syndrome. Arthritis Res Ther (2011) 1.02
Central pathways causing fatigue in neuro-inflammatory and autoimmune illnesses. BMC Med (2015) 0.97
T helper cytokines in dry eye disease. Exp Eye Res (2013) 0.97
Salivary gland and peripheral blood T helper 1 and 2 cell activity in Sjögren's syndrome compared with non-Sjögren's sicca syndrome. Ann Rheum Dis (2005) 0.95
Managing Sjögren's Syndrome and non-Sjögren Syndrome dry eye with anti-inflammatory therapy. Clin Ophthalmol (2014) 0.89
Th2 cytokine genotypes are associated with a milder form of primary Sjogren's syndrome. Ann Rheum Dis (2005) 0.86
Safety and efficacy of leflunomide in primary Sjögren's syndrome: a phase II pilot study. Ann Rheum Dis (2007) 0.84
The Significance of Ectopic Germinal Centers in the Minor Salivary Gland of Patients with Sjögren's Syndrome. J Korean Med Sci (2016) 0.75
CpG motifs in bacterial DNA trigger direct B-cell activation. Nature (1995) 12.24
DNA vaccines: immunology, application, and optimization*. Annu Rev Immunol (2000) 4.51
Varicella vaccination: evidence for frequent reactivation of the vaccine strain in healthy children. Nat Med (2000) 3.07
Systemic autoimmune disease arises from polyclonal B cell activation. J Exp Med (1987) 2.71
Human peripheral blood cells differentially recognize and respond to two distinct CPG motifs. J Immunol (2001) 2.61
Cutting edge: Role of Toll-like receptor 9 in CpG DNA-induced activation of human cells. J Immunol (2001) 2.49
NF-kappa B and Sp1 regulate transcription of the human monocyte chemoattractant protein-1 gene. J Immunol (1994) 2.40
Bacterial DNA containing CpG motifs stimulates lymphocyte-dependent protection of mice against lethal infection with intracellular bacteria. J Immunol (1999) 2.23
Contribution of CpG motifs to the immunogenicity of DNA vaccines. J Immunol (1997) 2.04
Genomic DNA released by dying cells induces the maturation of APCs. J Immunol (2001) 2.03
Transcriptional regulation of the human monocyte chemoattractant protein-1 gene. Cooperation of two NF-kappaB sites and NF-kappaB/Rel subunit specificity. J Biol Chem (1997) 1.85
Pathologic features of Behçet's syndrome: a review of Japanese autopsy registry data. Hum Pathol (1985) 1.85
A novel integrin-linked kinase-binding protein, affixin, is involved in the early stage of cell-substrate interaction. J Cell Biol (2001) 1.84
Human immunodeficiency virus infection induces both polyclonal and virus-specific B cell activation. J Clin Invest (1992) 1.84
Interferon (IFN) consensus sequence-binding protein, a transcription factor of the IFN regulatory factor family, regulates immune responses in vivo through control of interleukin 12 expression. J Exp Med (1997) 1.73
Long term prevention of allergic lung inflammation in a mouse model of asthma by CpG oligodeoxynucleotides. J Immunol (1999) 1.58
Distinct patterns of cytokine secretion characterize new onset synovitis versus chronic rheumatoid arthritis. J Rheumatol (1998) 1.55
A plasmid encoding murine granulocyte-macrophage colony-stimulating factor increases protection conferred by a malaria DNA vaccine. J Immunol (1998) 1.54
Aortitis syndrome (Takayasu's arteritis) associated with systemic lupus erythematosus. J Rheumatol (1989) 1.52
Activation of target-tissue immune-recognition molecules by double-stranded polynucleotides. Proc Natl Acad Sci U S A (1999) 1.48
Rapid immune activation by CpG motifs in bacterial DNA. Systemic induction of IL-6 transcription through an antioxidant-sensitive pathway. J Immunol (1996) 1.46
Studies of consomic mice bearing the Y chromosome of the BXSB mouse. J Immunol (1985) 1.44
Renal flares are common in patients with severe proliferative lupus nephritis treated with pulse immunosuppressive therapy: long-term followup of a cohort of 145 patients participating in randomized controlled studies. Arthritis Rheum (2002) 1.42
FK506 treatment of noninfectious uveitis. Am J Ophthalmol (1994) 1.38
Sterically stabilized cationic liposomes improve the uptake and immunostimulatory activity of CpG oligonucleotides. J Immunol (2001) 1.33
Autoimmunity and increased c-myb transcription. Science (1984) 1.27
Complexity of the cytokine and antibody response elicited by immunizing mice with Plasmodium yoelii circumsporozoite protein plasmid DNA. J Immunol (1995) 1.24
Microbial products induce autoimmune disease by an IL-12-dependent pathway. J Immunol (1997) 1.21
Protection against anthrax toxin by vaccination with a DNA plasmid encoding anthrax protective antigen. Vaccine (1999) 1.20
Severe cardiac toxicity in hematological stem cell transplantation: predictive value of reduced left ventricular ejection fraction. Bone Marrow Transplant (2001) 1.20
CpG oligodeoxynucleotides and interleukin-12 improve the efficacy of Mycobacterium bovis BCG vaccination in mice challenged with M. tuberculosis. Infect Immun (2000) 1.19
Proliferation of anti-DNA-producing NZB B cells in a non-autoimmune environment. J Immunol (1986) 1.17
Oncogene expression in autoimmune and normal peripheral blood mononuclear cells. J Exp Med (1986) 1.15
Transfer of heme oxygenase 1 cDNA by a replication-deficient adenovirus enhances interleukin 10 production from alveolar macrophages that attenuates lipopolysaccharide-induced acute lung injury in mice. Hum Gene Ther (2001) 1.14
Comparison of synovial tissue and synovial fluid as the source of nucleic acids for detection of Chlamydia trachomatis by polymerase chain reaction. Arthritis Rheum (1996) 1.12
Enhancement of cell-mediated immunity against HIV-1 induced by coinnoculation of plasmid-encoded HIV-1 antigen with plasmid expressing IL-12. J Immunol (1997) 1.11
Simultaneous induction of multiple antigen-specific cytotoxic T lymphocytes in nonhuman primates by immunization with a mixture of four Plasmodium falciparum DNA plasmids. Infect Immun (1998) 1.09
Induction of neonatal tolerance by plasmid DNA vaccination of mice. J Clin Invest (1996) 1.08
Efficacy, immunogenicity, safety, and use of live attenuated chickenpox vaccine. J Pediatr (1995) 1.08
Sequence analysis and expression of an X-linked, lymphocyte-regulated gene family (XLR). J Exp Med (1987) 1.07
Sex hormone levels correlate with the activity of cytokine-secreting cells in vivo. Immunology (2000) 1.06
NIH conference. Systemic lupus erythematosus. Ann Intern Med (1991) 1.06
Theoretical and experimental approaches to generalized autoimmunity. Immunol Rev (1990) 1.03
Plasmid DNA encoding transforming growth factor-beta1 suppresses chronic disease in a streptococcal cell wall-induced arthritis model. J Clin Invest (1998) 1.03
Heterogeneous expression and coordinate regulation of endogenous retroviral sequences in human peripheral blood mononuclear cells. AIDS Res Hum Retroviruses (1992) 1.02
Pathogenesis of systemic lupus erythematosus. Rheum Dis Clin North Am (1988) 1.02
CpG motifs of DNA vaccines induce the expression of chemokines and MHC class II molecules on myocytes. Eur J Immunol (2001) 1.01
CpG oligodeoxynucleotides induce murine macrophages to up-regulate chemokine mRNA expression. Cell Immunol (2000) 0.99
IgE receptor-positive non-B/non-T cells dominate the production of interleukin 4 and interleukin 6 in immunized mice. Proc Natl Acad Sci U S A (1995) 0.98
Immunomodulatory effects of a plasmid expressing B7-2 on human immunodeficiency virus-1-specific cell-mediated immunity induced by a plasmid encoding the viral antigen. Eur J Immunol (1997) 0.98
A suppressive oligodeoxynucleotide inhibits ocular inflammation. Clin Exp Immunol (2009) 0.98
Individual cells simultaneously produce both IL-4 and IL-6 in vivo. Cytokine (1994) 0.98
Disassociation of sex hormone levels and cytokine production in SLE patients. Lupus (2001) 0.96
Quantitation of IgM- and IgG-secreting B cells in the peripheral blood of patients with systemic lupus erythematosus. Arthritis Rheum (1991) 0.96
Toward clinical trials of DNA vaccines against malaria. Immunol Cell Biol (1997) 0.95
Response of peripheral blood mononuclear cells from lupus patients to stimulation by CpG oligodeoxynucleotides. Rheumatology (Oxford) (2003) 0.95
Autoantibody production is associated with polyclonal B cell activation in autoimmune mice which express the lpr or gld genes. Eur J Immunol (1988) 0.95
The interaction of the xid and me genes. J Immunol (1987) 0.95
Do DNA vaccines induce autoimmune disease? Hum Gene Ther (1997) 0.95
Chemical induction of HO-1 suppresses lupus nephritis by reducing local iNOS expression and synthesis of anti-dsDNA antibody. Clin Exp Immunol (2004) 0.95
Antigen-pulsed neutrophils bearing Ia antigens can induce T lymphocyte proliferative response to the syngeneic or semisyngeneic antigen-primed T lymphocytes. Transplantation (1980) 0.95
Activation of microglia and astrocytes by CpG oligodeoxynucleotides. Neuroreport (2001) 0.95
NIH conference. Angioimmunoblastic lymphadenopathy with dysproteinemia. Ann Intern Med (1988) 0.93
Phenotype and frequency of cells secreting IL-2, IL-4, IL-6, IL-10, IFN and TNF-alpha in human peripheral blood. Cytokine (1995) 0.93
Predictive factors for central nervous system involvement in non-Hodgkin's lymphoma: significance of very high serum LDH concentrations. Leuk Lymphoma (2000) 0.93
Acquisition and maturation of expressed B cell repertoires in normal and autoimmune mice. J Immunol (1988) 0.93
Cigarette smoking depletes cells spontaneously secreting Th(1) cytokines in the human airway. Cytokine (2001) 0.92
Prime-boost vaccination with plasmid DNA and a chimeric adenovirus type 5 vector with type 35 fiber induces protective immunity against HIV. Gene Ther (2005) 0.92
Dual infection with HIV-1 Thai subtype B and E. Lancet (1995) 0.92
Immune response induced by airway sensitization after influenza A virus infection depends on timing of antigen exposure in mice. J Virol (2001) 0.92
Murine cytomegalovirus infection-induced polyclonal B cell activation is independent of CD4+ T cells and CD40. Virology (1998) 0.92
Immune responses in asymptomatic HIV-1-infected patients after HIV-DNA immunization followed by highly active antiretroviral treatment. J Immunol (1999) 0.90
Increased activation and altered ratio of interferon-gamma: interleukin-4 secreting cells in MRL-lpr/lpr mice. Autoimmunity (1995) 0.90
DNAse treatment does not improve the survival of lupus prone (NZB x NZW)F1 mice. Lupus (1998) 0.90
Effect of HIV infection on the frequency of cytokine-secreting cells in human peripheral blood. AIDS Res Hum Retroviruses (1996) 0.90
The natural history of disease expression in CD4 and CD8 gene-deleted New Zealand black (NZB) mice. J Immunol (1996) 0.89
Genetic control of contact hypersensitivity. I. I-A subregion as well as non-H-2 loci codes for the gene of 2,4-dinitro-1-fluorobenzene antigen. Eur J Immunol (1980) 0.89
IFN-gamma is a potent inducer of Ig secretion by sort-purified murine B cells activated through the mIg, but not the CD40, signaling pathway. Int Immunol (1996) 0.89
Factors associated with the development of neonatal tolerance after the administration of a plasmid DNA vaccine. J Immunol (1999) 0.88
Development and validation of a tuberculosis prognostic score for smear-positive in-patients in Japan. Int J Tuberc Lung Dis (2013) 0.88
Outcomes after switching from one bisphosphonate to another in 146 patients at a single university hospital. Osteoporos Int (2008) 0.88
Effects of bacterial DNA on cytokine production by (NZB/NZW)F1 mice. J Immunol (1998) 0.87
Immune reconstitution assessed during five years after allogeneic bone marrow transplantation. Bone Marrow Transplant (2001) 0.86
Nucleotide sequence analysis of the approximately 35-kb segment containing interferon-gamma-inducible mouse proteasome activator genes. Immunogenetics (2001) 0.86
[Hematological abnormalities of primary Sjogren's syndrome]. Nihon Rinsho Meneki Gakkai Kaishi (2000) 0.86
Pathologically defined neuro-, vasculo-, entero-Behçet's disease. J Rheumatol (1985) 0.85
Idiotypy and autoimmunity. Arthritis Rheum (1986) 0.85
Persistence with bisphosphonate therapy including treatment courses with multiple sequential bisphosphonates in the real world. Osteoporos Int (2007) 0.85
Long-term remission in a patient with hepatosplenic gammadelta T cell lymphoma after cord blood stem cell transplantation following autologous peripheral blood stem cell transplantation. Bone Marrow Transplant (2006) 0.84
Genetic studies in NZB mice. VI. Association of autoimmune traits in recombinant inbred lines. J Immunol (1984) 0.84
Response of porcine peripheral blood mononuclear cells to CpG-containing oligodeoxynucleotides. Vet Microbiol (2001) 0.84
Successful treatment of refractory lupus-associated haemophagocytic lymphohistiocytosis with infliximab. Rheumatology (Oxford) (2007) 0.84
A prognostic score with pretransplant serum ferritin and disease status predicts outcome following reduced-intensity SCT. Bone Marrow Transplant (2011) 0.84
Administration of an IL-12-encoding DNA plasmid prevents the development of chronic graft-versus-host disease (GVHD). J Immunol (1999) 0.84
Contribution of interleukin-3 to antigen-induced Th2 cytokine production. Eur J Immunol (1996) 0.84
HIV-1-specific cell-mediated immunity is enhanced by co-inoculation of TCA3 expression plasmid with DNA vaccine. Immunology (1997) 0.83