PubRank

M Tomasz

Author PubWeight™ 48.29‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Isolation and structure of a covalent cross-link adduct between mitomycin C and DNA. Science 1987 1.91
2 Circular dichroism of mitomycin-DNA complexes. Evidence for a conformational change in DNA. Biochemistry 1977 1.57
3 The mode of interaction of mitomycin C with deoxyribonucleic acid and other polynucleotides in vitro. Biochemistry 1974 1.24
4 Reaction of DNA with chemically or enzymatically activated mitomycin C: isolation and structure of the major covalent adduct. Proc Natl Acad Sci U S A 1986 1.16
5 Recognition between mitomycin C and specific DNA sequences for cross-link formation. Biochemistry 1990 1.15
6 Interaction of metronidazole with nucleic acids in vitro. Mol Pharmacol 1977 1.15
7 Mitomycin C: a prototype bioreductive agent. Oncol Res 1994 1.06
8 Enzymology of mitomycin C metabolic activation in tumour tissue: implications for enzyme-directed bioreductive drug development. Biochem Pharmacol 1998 1.05
9 Mechanism of the isotopic exchange of the C-8 hydrogen of purines in nucleosides and in deoxyribonucleic acid. Biochemistry 1972 1.04
10 NMR and computational characterization of mitomycin cross-linked to adjacent deoxyguanosines in the minor groove of the d(T-A-C-G-T-A).d(T-A-C-G-T-A) duplex. Biochemistry 1990 1.03
11 Cellular pharmacology of quinone bioreductive alkylating agents. Cancer Metastasis Rev 1993 0.99
12 Isolation and structure of an intrastrand cross-link adduct of mitomycin C and DNA. Biochemistry 1992 0.99
13 Recognition of specific DNA sequences by mitomycin C for alkylation. Biochemistry 1992 0.97
14 Mitomycin C-DNA adducts generated by DT-diaphorase. Revised mechanism of the enzymatic reductive activation of mitomycin C. Biochemistry 1997 0.97
15 Reaction of acid-activated mitomycin C with calf thymus DNA and model guanines: elucidation of the base-catalyzed degradation of N7-alkylguanine nucleosides. Biochemistry 1987 0.96
16 Selective recognition of the m5CpG dinucleotide sequence in DNA by mitomycin C for alkylation and cross-linking. Bioorg Med Chem 1995 0.96
17 Reductive metabolism and alkylating activity of mitomycin C induced by rat liver microsomes. Biochemistry 1981 0.93
18 Bending of DNA by the mitomycin C-induced, GpG intrastrand cross-link. Chem Res Toxicol 1996 0.93
19 The major mitomycin C-DNA monoadduct is cytotoxic but not mutagenic in Escherichia coli. Chem Res Toxicol 1998 0.92
20 Lack of Z-DNA conformation in mitomycin-modified polynucleotides having inverted circular dichroism. Proc Natl Acad Sci U S A 1983 0.92
21 Adducts of mitomycin C and DNA in EMT6 mouse mammary tumor cells: effects of hypoxia and dicumarol on adduct patterns. Cancer Res 1993 0.91
22 The chemistry of pseudouridine. VII. Selective cleavage of polynucleotides containing pseudouridylic acid residues by a unique photochemical reaction. Biochemistry 1966 0.91
23 Mammalian 3-methyladenine DNA glycosylase protects against the toxicity and clastogenicity of certain chemotherapeutic DNA cross-linking agents. Cancer Res 1998 0.91
24 Novel assay of 7-alkylation of guanine residues in DNA. Application to nitrogen mustard, triethylenemelamine and mitomycin C. Biochim Biophys Acta 1970 0.90
25 Extreme lability of the C-8 proton: a consequence of 7-methylation of guanine residues in model compounds and in DNA and its analytical application. Biochim Biophys Acta 1970 0.89
26 Structure of adduct X, the last unknown of the six major DNA adducts of mitomycin C formed in EMT6 mouse mammary tumor cells. Chem Res Toxicol 2000 0.89
27 Effect of site-specifically located mitomycin C-DNA monoadducts on in vitro DNA synthesis by DNA polymerases. Biochemistry 1993 0.88
28 H2O2 generation during the redox cycle of mitomycin C and dna-bound mitomycin C. Chem Biol Interact 1976 0.88
29 Electrostatic complexes of mitomycin C with nucleic acids and polyanions. Biochim Biophys Acta 1978 0.88
30 Solution structure of the monoalkylated mitomycin C-DNA complex. J Mol Biol 1995 0.88
31 Reductive activation of mitomycin A by thiols. Org Lett 2001 0.87
32 Reassignment of the guanine-binding mode of reduced mitomycin C. Biochemistry 1986 0.86
33 Formation of a major DNA adduct of the mitomycin metabolite 2,7-diaminomitosene in EMT6 mouse mammary tumor cells treated with mitomycin C. Oncol Res 1998 0.85
34 Altered physiochemical properties of the deoxyribonucleic acid-mitomycin C complex. Evidence for the conformational change in deoxyribonucleic acid. Biochemistry 1982 0.84
35 Mitomycin C linked to DNA minor groove binding agents: synthesis, reductive activation, DNA binding and cross-linking properties and in vitro antitumor activity. Bioorg Med Chem 1999 0.83
36 Reactivity of mitomycin C with synthetic polyribonucleotides containing guanine or guanine analogs. Biochim Biophys Acta 1982 0.83
37 Duplex oligodeoxyribonucleotides cross-linked by mitomycin C at a single site: synthesis, properties, and cross-link reversibility. Biochemistry 1990 0.83
38 Vacuum ultraviolet circular dichroism of double stranded nucleic acids. Photochem Photobiol 1986 0.82
39 Studies on the mechanism of the cytotoxic action of the mitomycin antibiotics in hypoxic and oxygenated EMT6 cells. Adv Enzyme Regul 1993 0.80
40 Structural and function modification of DNA by mitomycin C. Mechanism of the DNA sequence specificity of mitomycins. Nucleic Acids Symp Ser 1995 0.79
41 Reductive alkylation of DNA by mitomycin A, a mitomycin with high redox potential. Biochemistry 1991 0.79
42 Reactivity of guanine at m5CpG steps in DNA: evidence for electronic effects transmitted through the base pairs. Chem Biol 1999 0.79
43 Binding of 2,7-diaminomitosene to DNA: model for the precovalent recognition of DNA by activated mitomycin C. Biochemistry 1995 0.79
44 Mitosene-DNA adducts. Characterization of two major DNA monoadducts formed by 1,10-bis(acetoxy)-7-methoxymitosene upon reductive activation. Biochemistry 1997 0.78
45 Bioreductive metabolism of mitomycin C in EMT6 mouse mammary tumor cells: cytotoxic and non-cytotoxic pathways, leading to different types of DNA adducts. The effect of dicumarol. Biochem Pharmacol 2001 0.78
46 Solution structure of a guanine-N7-linked complex of the mitomycin C metabolite 2,7-diaminomitosene and DNA. Basis of sequence selectivity. Biochemistry 2001 0.78
47 Absence of strand breaks in deoxyribonucleic acid treated with metronidazole. Antimicrob Agents Chemother 1978 0.78
48 Orientation isomers of the mitomycin C interstrand cross-link in non-self-complementary DNA. Differential effect of the two isomers on restriction endonuclease cleavage at a nearby site. Biochemistry 1993 0.77
49 Periodate oxidation of pseudouridine. Biochim Biophys Acta 1965 0.77
50 Selective activation of mitomycin A by thiols to form DNA cross-links and monoadducts: biochemical basis for the modulation of mitomycin cytotoxicity by the quinone redox potential. J Med Chem 2001 0.77
51 A mitomycin-N6-deoxyadenosine adduct isolated from DNA. Chem Res Toxicol 1998 0.75
52 Inhibitory effects of mitomycin-related compounds lacking the C1-C2 aziridine ring. Antimicrob Agents Chemother 1972 0.75
53 Antisense sequence-directed cross-linking of DNA oligonucleotides by mitomycin C. Bioconjug Chem 1997 0.75
54 Interaction of the antitumor antibiotic mitomycin C with Z-DNA. J Biomol Struct Dyn 1988 0.75
55 Antisense sequence-directed cross-linking of RNA oligonucleotides by mitomycin. Anticancer Drug Des 1997 0.75
56 Conjugation of glutathione and other thiols with bioreductively activated mitomycin C. Effect of thiols on the reductive activation rate. Chem Res Toxicol 1994 0.75
57 Effects of glutathione on alkylation and cross-linking of DNA by mitomycin C. Isolation of a ternary glutathione-mitomycin-DNA adduct. Chem Res Toxicol 1994 0.75