Published in Am J Physiol on February 01, 1998
HET0016, a potent and selective inhibitor of 20-HETE synthesizing enzyme. Br J Pharmacol (2001) 1.78
20-hydroxyeicosatetraeonic acid: a new target for the treatment of hypertension. J Cardiovasc Pharmacol (2010) 1.55
20-HETE-mediated cytotoxicity and apoptosis in ischemic kidney epithelial cells. Am J Physiol Renal Physiol (2008) 1.22
Effects of cytochrome P-450 metabolites of arachidonic acid on the epithelial sodium channel (ENaC). Am J Physiol Renal Physiol (2011) 1.11
Renal renin-angiotensin system. Contrib Nephrol (2004) 1.09
Effects of 20-HETE and 19(S)-HETE on rabbit proximal straight tubule volume transport. Am J Physiol Renal Physiol (2000) 1.07
20-HETE and blood pressure regulation: clinical implications. Cardiol Rev (2013) 1.02
Postmenopausal hypertension: role of 20-HETE. Am J Physiol Regul Integr Comp Physiol (2011) 0.98
Role of endogenous CYP450 metabolites of arachidonic acid in maintaining the glomerular protein permeability barrier. Am J Physiol Renal Physiol (2007) 0.97
Androgen-sensitive hypertension associates with upregulated vascular CYP4A12-20-HETE synthase. J Am Soc Nephrol (2013) 0.94
Molecular mechanisms of renal blood flow autoregulation. Curr Vasc Pharmacol (2014) 0.92
Contribution of cytochrome P450 4A isoforms to renal functional response to inhibition of nitric oxide production in the rat. J Physiol (2003) 0.89
CYP-omega-hydroxylation-dependent metabolites of arachidonic acid inhibit the basolateral 10 pS chloride channel in the rat thick ascending limb. Kidney Int (2009) 0.88
Modulation of vascular O2 responses by cytochrome 450-4A omega-hydroxylase metabolites in Dahl salt-sensitive rats. Microcirculation (2009) 0.86
Regulation of ENaC-Mediated Sodium Reabsorption by Peroxisome Proliferator-Activated Receptors. PPAR Res (2010) 0.80
Impaired myogenic response and autoregulation of cerebral blood flow is rescued in CYP4A1 transgenic Dahl salt-sensitive rat. Am J Physiol Regul Integr Comp Physiol (2014) 0.79
Clinical Implications of 20-Hydroxyeicosatetraenoic Acid in the Kidney, Liver, Lung and Brain: An Emerging Therapeutic Target. Pharmaceutics (2017) 0.75
Molecular mechanisms and cell signaling of 20-hydroxyeicosatetraenoic acid in vascular pathophysiology. Front Biosci (Landmark Ed) (2016) 0.75
Modulation of arachidonic Acid metabolism in the rat kidney by sulforaphane: implications for regulation of blood pressure. ISRN Pharmacol (2014) 0.75
Cytochrome P4504A inhibitors attenuate the exaggerated natriuretic response to volume expansion in thyroidectomized rats. Physiol Rep (2014) 0.75
Production of 20-HETE and its role in autoregulation of cerebral blood flow. Circ Res (2000) 2.67
A genomic-systems biology map for cardiovascular function. Science (2001) 2.09
Brown Norway chromosome 13 confers protection from high salt to consomic Dahl S rat. Hypertension (2001) 1.99
Mechanism of action of cerebral epoxyeicosatrienoic acids on cerebral arterial smooth muscle. Am J Physiol (1992) 1.80
The role of the kidney in hypertension. JAMA (1996) 1.80
Role of cytochrome P-450 enzymes and metabolites of arachidonic acid in the control of vascular tone. J Vasc Res (1995) 1.76
Molecular characterization of an arachidonic acid epoxygenase in rat brain astrocytes. Stroke (1996) 1.68
Functional hyperemia in the brain: hypothesis for astrocyte-derived vasodilator metabolites. Stroke (1998) 1.58
Formation and actions of 20-hydroxyeicosatetraenoic acid in rat renal arterioles. Am J Physiol (1996) 1.53
Actions of epoxygenase metabolites on the preglomerular vasculature. J Am Soc Nephrol (1996) 1.50
Consomic rat model systems for physiological genomics. Acta Physiol Scand (2004) 1.50
20-Hydroxyeicosatetraenoic acid is an endogenous vasoconstrictor of canine renal arcuate arteries. Circ Res (1993) 1.48
Genetic contamination of Dahl SS/Jr rats. Impact on studies of salt-sensitive hypertension. Hypertension (1994) 1.48
20-HETE is an endogenous inhibitor of the large-conductance Ca(2+)-activated K+ channel in renal arterioles. Am J Physiol (1996) 1.46
The renal medulla and hypertension. Hypertension (1995) 1.46
Effects of 17-octadecynoic acid, a suicide-substrate inhibitor of cytochrome P450 fatty acid omega-hydroxylase, on renal function in rats. J Pharmacol Exp Ther (1994) 1.38
Endotoxin augments cerebral hyperemic response to halothane by inducing nitric oxide synthase and cyclooxygenase. Anesth Analg (2000) 1.37
20-HETE agonists and antagonists in the renal circulation. Am J Physiol (1999) 1.37
Stereospecific effects of epoxyeicosatrienoic acids on renal vascular tone and K(+)-channel activity. Am J Physiol (1996) 1.33
Inhibition of renal vascular 20-HETE production impairs autoregulation of renal blood flow. Am J Physiol (1994) 1.32
Identification of a putative microvascular oxygen sensor. Circ Res (1996) 1.30
Role of nitric oxide in renal papillary blood flow and sodium excretion. Hypertension (1992) 1.26
Inhibition of brain P-450 arachidonic acid epoxygenase decreases baseline cerebral blood flow. Am J Physiol (1996) 1.24
Role of tyrosine kinase and PKC in the vasoconstrictor response to 20-HETE in renal arterioles. Hypertension (1999) 1.24
Evaluation of laser-Doppler flowmetry as a measure of tissue blood flow. J Appl Physiol (1985) (1986) 1.21
Characterization of a new model for the study of pressure-natriuresis in the rat. Am J Physiol (1985) 1.19
Anti-inflammatory and safety profile of DuP 697, a novel orally effective prostaglandin synthesis inhibitor. J Pharmacol Exp Ther (1990) 1.19
Inhibition of 20-HETE production contributes to the vascular responses to nitric oxide. Hypertension (1997) 1.18
Role of 20-HETE in elevating chloride transport in the thick ascending limb of Dahl SS/Jr rats. Hypertension (1999) 1.17
Altered renal hemodynamics and impaired myogenic responses in the fawn-hooded rat. Am J Physiol (1999) 1.17
Effect of P-450 omega-hydroxylase metabolites of arachidonic acid on tubuloglomerular feedback. Am J Physiol (1994) 1.16
Nitric oxide-20-hydroxyeicosatetraenoic acid interaction in the regulation of K+ channel activity and vascular tone in renal arterioles. Circ Res (1998) 1.12
Contribution of 20-HETE to the vasodilator actions of nitric oxide in renal arteries. Am J Physiol (1998) 1.11
Renin gene transfer restores angiogenesis and vascular endothelial growth factor expression in Dahl S rats. Hypertension (2001) 1.11
Abnormal renal hemodynamics and pressure-natriuresis relationship in Dahl salt-sensitive rats. Am J Physiol (1986) 1.09
Role of cytochrome P450 metabolites of arachidonic acid in hypertension. Curr Drug Metab (2004) 1.09
Role of blood volume expansion in Dahl rat model of hypertension. Am J Physiol (1990) 1.09
Cytochrome P450 metabolites of arachidonic acid as intracellular signaling molecules in vascular tissue. J Vasc Res (1997) 1.08
Renal and cardiovascular actions of 20-hydroxyeicosatetraenoic acid and epoxyeicosatrienoic acids. Clin Exp Pharmacol Physiol (2000) 1.06
Renal P450 metabolites of arachidonic acid and the development of hypertension in Dahl salt-sensitive rats. Am J Hypertens (1997) 1.06
Altered renal P-450 metabolism of arachidonic acid in Dahl salt-sensitive rats. Am J Physiol (1994) 1.06
Coexistence of two types of Ca(2+)-activated K+ channels in rat renal arterioles. Am J Physiol (1996) 1.06
Regulation of P-450 4A activity in the glomerulus of the rat. Am J Physiol (1999) 1.04
Fluorometric assay for urea in urine, plasma, and tubular fluid. Anal Biochem (1979) 1.04
Impaired autoregulation of renal blood flow in the fawn-hooded rat. Am J Physiol (1999) 1.04
Role of cGMP versus 20-HETE in the vasodilator response to nitric oxide in rat cerebral arteries. Am J Physiol Heart Circ Physiol (2000) 1.03
Cytochrome P4504A genotype cosegregates with hypertension in Dahl S rats. Hypertension (1996) 1.03
Role of 20-HETE in elevating loop chloride reabsorption in Dahl SS/Jr rats. Hypertension (1996) 1.03
Effects of lipid-lowering agents in the Dahl salt-sensitive rat. Hypertension (1998) 1.03
Contribution of 20-HETE to vasodilator actions of nitric oxide in the cerebral microcirculation. Stroke (1999) 1.03
Relationship between renal perfusion pressure and blood flow in different regions of the kidney. Am J Physiol (1993) 1.02
Electrical and mechanical responses of rat middle cerebral arteries to reduced PO2 and prostacyclin. Am J Physiol (1999) 1.02
Spontaneous flow oscillations in the cerebral cortex during acute changes in mean arterial pressure. J Cereb Blood Flow Metab (1992) 1.01
Glomerular hyperfiltration in hypertensive African Americans. Hypertension (2000) 1.01
Pilon fractures of the proximal interphalangeal joint. J Hand Surg Am (1991) 1.01
Epoxyeicosatrienoic acids constrict isolated pressurized rabbit pulmonary arteries. Am J Physiol Lung Cell Mol Physiol (2000) 1.01
Role of renal interstitial hydrostatic pressure in the pressure diuresis response. Am J Physiol (1989) 0.99
Cytochrome P-450 inhibitors alter afferent arteriolar responses to elevations in pressure. Am J Physiol (1994) 0.99
Influence of angiotensin II on pressure natriuresis and renal hemodynamics in volume-expanded rats. Am J Physiol (1991) 0.99
Inhibitors of cytochrome P-450 attenuate the myogenic response of dog renal arcuate arteries. Circ Res (1991) 0.98
Reversal of microvascular rarefaction and reduced renal mass hypertension. Hypertension (1997) 0.98
Role of cytochrome P-450 in elevating renal vascular tone in spontaneously hypertensive rats. J Vasc Res (1993) 0.98
Response of resistance arteries to reduced PO2 and vasodilators during hypertension and elevated salt intake. Am J Physiol (1997) 0.98
Pressurization of isolated renal arteries increases inositol trisphosphate and diacylglycerol. Am J Physiol (1994) 0.98
Heme oxygenase-1 induction attenuates inducible nitric oxide synthase expression and proteinuria in glomerulonephritis. J Am Soc Nephrol (1999) 0.97
Role of inducible nitric oxide synthase and cyclooxygenase-2 in endotoxin-induced cerebral hyperemia. Stroke (1998) 0.96
Effect of renal medullary circulation on arterial pressure. J Hypertens Suppl (1992) 0.96
Cytochrome P450 metabolites of arachidonic acid in the control of renal function. Curr Opin Nephrol Hypertens (2001) 0.96
Nitric oxide modulates vascular tone in preglomerular arterioles. Hypertension (1992) 0.94
Cardiac output and renal function during insulin hypertension in Sprague-Dawley rats. Am J Physiol (1996) 0.94
Abnormal pressure-diuresis-natriuresis response in spontaneously hypertensive rats. Am J Physiol (1985) 0.94
Renal medullary interstitial infusion of diltiazem alters sodium and water excretion in rats. Am J Physiol (1992) 0.94
Effect of urea concentration of pelvic fluid on renal concentrating ability. Am J Physiol (1980) 0.94
Cytochrome P-450 omega-hydroxylase: a potential O(2) sensor in rat arterioles and skeletal muscle cells. Am J Physiol Heart Circ Physiol (2001) 0.94
Altered mechanisms underlying hypoxic dilation of skeletal muscle resistance arteries of hypertensive versus normotensive Dahl rats. Microcirculation (2001) 0.93
Genetically defined risk of salt sensitivity in an intercross of Brown Norway and Dahl S rats. Physiol Genomics (2000) 0.93
Fluorescent HPLC assay for 20-HETE and other P-450 metabolites of arachidonic acid. Am J Physiol Heart Circ Physiol (2000) 0.92
Elevated renovascular tone in young spontaneously hypertensive rats. Role of cytochrome P-450. Hypertension (1993) 0.91
Inhibition of renal outer medullary 20-HETE production produces hypertension in Lewis rats. Hypertension (1997) 0.91
Role of kinins and angiotensin II in the renal hemodynamic response to captopril. Am J Physiol (1991) 0.91
Abnormal pressure-natriuresis in hypertension: role of cytochrome P450 metabolites of arachidonic acid. Am J Hypertens (2001) 0.90
Rat survival to anthrax lethal toxin is likely controlled by a single gene. Pharmacogenomics J (2007) 0.90
20-HETE modulates myogenic response of skeletal muscle resistance arteries from hypertensive Dahl-SS rats. Am J Physiol Heart Circ Physiol (2001) 0.89
Hemodynamics and blood volume in angiotensin II salt-dependent hypertension in dogs. Am J Physiol (1989) 0.89
A common pathway for regulation of nutritive blood flow to the brain: arterial muscle membrane potential and cytochrome P450 metabolites. Acta Physiol Scand (1998) 0.89
Transfer of a salt-resistant renin allele raises blood pressure in Dahl salt-sensitive rats. Hypertension (1997) 0.89
Cytochrome P450 metabolites of arachidonic acid play a role in the enhanced cardiac dysfunction in diabetic rats following ischaemic reperfusion injury. Auton Autacoid Pharmacol (2009) 0.89
Effects of 12-HETE on isolated dog renal arcuate arteries. Am J Physiol (1991) 0.88
Cytochrome P-450 omega-hydroxylase senses O2 in hamster muscle, but not cheek pouch epithelium, microcirculation. Am J Physiol (1999) 0.88
Effects of renin gene transfer on blood pressure and renin gene expression in a congenic strain of Dahl salt-resistant rats. J Clin Invest (1996) 0.88
Resistance to metabolic actions of insulin and its role in hypertension. Am J Hypertens (1994) 0.87
Renal effect of prostaglandin synthetase inhibition in rats: micropuncture studies. Am J Physiol (1978) 0.87
Reversal of delayed vasospasm by TS-011 in the dual hemorrhage dog model of subarachnoid hemorrhage. AJNR Am J Neuroradiol (2006) 0.87
Role of 20-hydroxyeicosatetraenoic acid in altering vascular reactivity in diabetes. Auton Autacoid Pharmacol (2009) 0.86