Published in Proc Natl Acad Sci U S A on March 17, 1998
Epidemiology, genetics, and ecology of toxigenic Vibrio cholerae. Microbiol Mol Biol Rev (1998) 8.36
Ecological fitness, genomic islands and bacterial pathogenicity. A Darwinian view of the evolution of microbes. EMBO Rep (2001) 4.78
Biodiversity of vibrios. Microbiol Mol Biol Rev (2004) 4.25
tmRNAs that encode proteolysis-inducing tags are found in all known bacterial genomes: A two-piece tmRNA functions in Caulobacter. Proc Natl Acad Sci U S A (2000) 3.83
Cholera. Lancet (2012) 3.80
Pathogenicity islands in bacterial pathogenesis. Clin Microbiol Rev (2004) 3.77
Integration sites for genetic elements in prokaryotic tRNA and tmRNA genes: sublocation preference of integrase subfamilies. Nucleic Acids Res (2002) 3.67
Evidence of a large novel gene pool associated with prokaryotic genomic islands. PLoS Genet (2005) 2.71
Evaluation of genomic island predictors using a comparative genomics approach. BMC Bioinformatics (2008) 2.62
Genotypes associated with virulence in environmental isolates of Vibrio cholerae. Appl Environ Microbiol (2001) 2.41
A Vibrio cholerae LysR homolog, AphB, cooperates with AphA at the tcpPH promoter to activate expression of the ToxR virulence cascade. J Bacteriol (1999) 2.33
Protective role of autophagy against Vibrio cholerae cytolysin, a pore-forming toxin from V. cholerae. Proc Natl Acad Sci U S A (2007) 2.27
Virulence genes in environmental strains of Vibrio cholerae. Appl Environ Microbiol (2000) 2.21
The Vibrio cholerae genome contains two unique circular chromosomes. Proc Natl Acad Sci U S A (1998) 2.18
Salmonella enterica serovar typhi uses type IVB pili to enter human intestinal epithelial cells. Infect Immun (2000) 2.04
espC pathogenicity island of enteropathogenic Escherichia coli encodes an enterotoxin. Infect Immun (2001) 2.03
Genetic diversity and population structure of Vibrio cholerae. J Clin Microbiol (1999) 2.00
Analysis of clinical and environmental strains of nontoxigenic Vibrio cholerae for susceptibility to CTXPhi: molecular basis for origination of new strains with epidemic potential. Infect Immun (1998) 1.99
Altered expression of the ToxR-regulated porins OmpU and OmpT diminishes Vibrio cholerae bile resistance, virulence factor expression, and intestinal colonization. Proc Natl Acad Sci U S A (2000) 1.94
Vibrio cholerae H-NS silences virulence gene expression at multiple steps in the ToxR regulatory cascade. J Bacteriol (2000) 1.92
Incidence, virulence factors, and clonality among clinical strains of non-O1, non-O139 Vibrio cholerae isolates from hospitalized diarrheal patients in Kolkata, India. J Clin Microbiol (2009) 1.82
Transcriptional profiling of Vibrio cholerae recovered directly from patient specimens during early and late stages of human infection. Infect Immun (2005) 1.78
The majority of genes in the pathogenic Neisseria species are present in non-pathogenic Neisseria lactamica, including those designated as 'virulence genes'. BMC Genomics (2006) 1.77
Discovery of novel Vibrio cholerae VSP-II genomic islands using comparative genomic analysis. FEMS Microbiol Lett (2010) 1.77
Characterization of VPI pathogenicity island and CTXphi prophage in environmental strains of Vibrio cholerae. J Bacteriol (2001) 1.76
Clinical and environmental isolates of Vibrio cholerae serogroup O141 carry the CTX phage and the genes encoding the toxin-coregulated pili. J Clin Microbiol (2001) 1.73
Evolutionary relationships of pathogenic clones of Vibrio cholerae by sequence analysis of four housekeeping genes. Infect Immun (1999) 1.73
ssrA (tmRNA) plays a role in Salmonella enterica serovar Typhimurium pathogenesis. J Bacteriol (2000) 1.70
Identification of genes in an extraintestinal isolate of Escherichia coli with increased expression after exposure to human urine. Infect Immun (1999) 1.68
Evidence for the emergence of non-O1 and non-O139 Vibrio cholerae strains with pathogenic potential by exchange of O-antigen biosynthesis regions. Infect Immun (2002) 1.67
Infectious CTXPhi and the vibrio pathogenicity island prophage in Vibrio mimicus: evidence for recent horizontal transfer between V. mimicus and V. cholerae. Infect Immun (2000) 1.64
The crystal structure of AphB, a virulence gene activator from Vibrio cholerae, reveals residues that influence its response to oxygen and pH. Mol Microbiol (2012) 1.64
Sialic acid catabolism confers a competitive advantage to pathogenic vibrio cholerae in the mouse intestine. Infect Immun (2009) 1.62
Ferric dicitrate transport system (Fec) of Shigella flexneri 2a YSH6000 is encoded on a novel pathogenicity island carrying multiple antibiotic resistance genes. Infect Immun (2001) 1.61
Analysis of an autoregulatory loop controlling ToxT, cholera toxin, and toxin-coregulated pilus production in Vibrio cholerae. J Bacteriol (1999) 1.57
The virulence regulatory protein ToxR mediates enhanced bile resistance in Vibrio cholerae and other pathogenic Vibrio species. Infect Immun (2000) 1.56
Genetic diversity of Vibrio cholerae in Chesapeake Bay determined by amplified fragment length polymorphism fingerprinting. Appl Environ Microbiol (2000) 1.53
Multilocus sequence typing has better discriminatory ability for typing Vibrio cholerae than does pulsed-field gel electrophoresis and provides a measure of phylogenetic relatedness. J Clin Microbiol (2003) 1.53
Evidence for reductive genome evolution and lateral acquisition of virulence functions in two Corynebacterium pseudotuberculosis strains. PLoS One (2011) 1.53
Crossing the line: selection and evolution of virulence traits. PLoS Pathog (2006) 1.49
Evolutionary genetic analysis of the emergence of epidemic Vibrio cholerae isolates on the basis of comparative nucleotide sequence analysis and multilocus virulence gene profiles. J Clin Microbiol (2004) 1.46
Three pathogenicity islands of Vibrio cholerae can excise from the chromosome and form circular intermediates. J Bacteriol (2007) 1.45
The virulence activator AphA links quorum sensing to pathogenesis and physiology in Vibrio cholerae by repressing the expression of a penicillin amidase gene on the small chromosome. J Bacteriol (2003) 1.45
Cholera outbreaks in Nigeria are associated with multidrug resistant atypical El Tor and non-O1/non-O139 Vibrio cholerae. PLoS Negl Trop Dis (2013) 1.43
The pan-genome of the animal pathogen Corynebacterium pseudotuberculosis reveals differences in genome plasticity between the biovar ovis and equi strains. PLoS One (2013) 1.42
Virulence and the environment: a novel role for Vibrio cholerae toxin-coregulated pili in biofilm formation on chitin. J Bacteriol (2005) 1.40
Characterization of the role of the ToxR-modulated outer membrane porins OmpU and OmpT in Vibrio cholerae virulence. J Bacteriol (2001) 1.38
The ToxR-mediated organic acid tolerance response of Vibrio cholerae requires OmpU. J Bacteriol (2001) 1.38
An in vivo expression technology screen for Vibrio cholerae genes expressed in human volunteers. Proc Natl Acad Sci U S A (2007) 1.38
Diverse CTX phages among toxigenic Vibrio cholerae O1 and O139 strains isolated between 1994 and 2002 in an area where cholera is endemic in Bangladesh. J Clin Microbiol (2004) 1.37
Phylogeny of Vibrio cholerae based on recA sequence. Infect Immun (2000) 1.37
Characterization of Vibrio cholerae O1 El Tor biotype variant clinical isolates from Bangladesh and Haiti, including a molecular genetic analysis of virulence genes. J Clin Microbiol (2011) 1.36
Molecular characterization of a new ribotype of Vibrio cholerae O139 Bengal associated with an outbreak of cholera in Bangladesh. J Clin Microbiol (1999) 1.30
The genome of non-O1 Vibrio cholerae NRT36S demonstrates the presence of pathogenic mechanisms that are distinct from those of O1 Vibrio cholerae. Infect Immun (2007) 1.30
Genetic and transcriptional analyses of the Vibrio cholerae mannose-sensitive hemagglutinin type 4 pilus gene locus. J Bacteriol (1999) 1.29
Microarray-based detection of genetic heterogeneity, antimicrobial resistance, and the viable but nonculturable state in human pathogenic Vibrio spp. Proc Natl Acad Sci U S A (2005) 1.29
Differential transcription of the tcpPH operon confers biotype-specific control of the Vibrio cholerae ToxR virulence regulon. Infect Immun (1999) 1.29
A region of the transmembrane regulatory protein ToxR that tethers the transcriptional activation domain to the cytoplasmic membrane displays wide divergence among Vibrio species. J Bacteriol (2000) 1.28
Mechanism of ToxT-dependent transcriptional activation at the Vibrio cholerae tcpA promoter. J Bacteriol (2002) 1.27
Lysogenic conversion of environmental Vibrio mimicus strains by CTXPhi. Infect Immun (1999) 1.27
Molecular evolution of the pathogenicity island of enterotoxigenic Bacteroides fragilis strains. J Bacteriol (1999) 1.26
Comparative and genetic analyses of the putative Vibrio cholerae lipopolysaccharide core oligosaccharide biosynthesis (wav) gene cluster. Infect Immun (2002) 1.25
PIPS: pathogenicity island prediction software. PLoS One (2012) 1.23
Detection and transformation of genome segments that differ within a coastal population of Vibrio cholerae strains. Appl Environ Microbiol (2007) 1.23
Requirements for Vibrio cholerae HapR binding and transcriptional repression at the hapR promoter are distinct from those at the aphA promoter. J Bacteriol (2005) 1.23
Pandemic spread of cholera: genetic diversity and relationships within the seventh pandemic clone of Vibrio cholerae determined by amplified fragment length polymorphism. J Clin Microbiol (2002) 1.21
Differential activation of the tcpPH promoter by AphB determines biotype specificity of virulence gene expression in Vibrio cholerae. J Bacteriol (2000) 1.21
Crystal structure of the virulence gene activator AphA from Vibrio cholerae reveals it is a novel member of the winged helix transcription factor superfamily. J Biol Chem (2005) 1.21
Vibrio cholerae ToxT independently activates the divergently transcribed aldA and tagA genes. J Bacteriol (2005) 1.21
Four genomic islands that mark post-1995 pandemic Vibrio parahaemolyticus isolates. BMC Genomics (2006) 1.19
A glimpse into the expanded genome content of Vibrio cholerae through identification of genes present in environmental strains. J Bacteriol (2005) 1.19
CTXphi-independent production of the RS1 satellite phage by Vibrio cholerae. Proc Natl Acad Sci U S A (2003) 1.15
Pathogenic clones versus environmentally driven population increase: analysis of an epidemic of the human fungal pathogen Coccidioides immitis. J Clin Microbiol (2000) 1.15
Phagocytic cell killing mediated by secreted cytotoxic factors of Vibrio cholerae. Infect Immun (2000) 1.14
Phenotypic and genotypic characteristics and epidemiological significance of ctx+ strains of Vibrio cholerae isolated from seafood in Malaysia. Appl Environ Microbiol (2004) 1.13
Comparative genomic analyses of the vibrio pathogenicity island and cholera toxin prophage regions in nonepidemic serogroup strains of Vibrio cholerae. Appl Environ Microbiol (2003) 1.13
Protein coding palindromes are a unique but recurrent feature in Rickettsia. Genome Res (2002) 1.13
Genomic relatedness of the new Matlab variants of Vibrio cholerae O1 to the classical and El Tor biotypes as determined by pulsed-field gel electrophoresis. J Clin Microbiol (2005) 1.13
Traffic at the tmRNA gene. J Bacteriol (2003) 1.12
Alternative mechanism of cholera toxin acquisition by Vibrio cholerae: generalized transduction of CTXPhi by bacteriophage CP-T1. Infect Immun (1999) 1.12
Vibrio vulnificus has the transmembrane transcription activator ToxRS stimulating the expression of the hemolysin gene vvhA. J Bacteriol (2000) 1.12
Identification and characterization of putative virulence genes and gene clusters in Aeromonas hydrophila PPD134/91. Appl Environ Microbiol (2005) 1.11
The high-pathogenicity island of Yersinia enterocolitica Ye8081 undergoes low-frequency deletion but not precise excision, suggesting recent stabilization in the genome. Infect Immun (1999) 1.10
Comparison of Vibrio cholerae pathogenicity islands in sixth and seventh pandemic strains. Infect Immun (2001) 1.09
Molecular characterization of a new variant of toxin-coregulated pilus protein (TcpA) in a toxigenic non-O1/Non-O139 strain of Vibrio cholerae. Infect Immun (2000) 1.08
Vibrio cholerae VibF is required for vibriobactin synthesis and is a member of the family of nonribosomal peptide synthetases. J Bacteriol (2000) 1.08
Examination of diverse toxin-coregulated pilus-positive Vibrio cholerae strains fails to demonstrate evidence for Vibrio pathogenicity island phage. Infect Immun (2003) 1.08
Pathogenic potential of environmental Vibrio cholerae strains carrying genetic variants of the toxin-coregulated pilus pathogenicity island. Infect Immun (2003) 1.07
ToxR interferes with CRP-dependent transcriptional activation of ompT in Vibrio cholerae. Mol Microbiol (2002) 1.07
Phage-bacterial interactions in the evolution of toxigenic Vibrio cholerae. Virulence (2012) 1.06
Gene cluster for assembly of pilus colonization factor antigen III of enterotoxigenic Escherichia coli. Infect Immun (2001) 1.05
The vibrio pathogenicity island of epidemic Vibrio cholerae forms precise extrachromosomal circular excision products. J Bacteriol (2003) 1.04
Cholera epidemiology in Nigeria: an overview. Pan Afr Med J (2012) 1.03
The Vibrio cholerae virulence regulatory cascade controls glucose uptake through activation of TarA, a small regulatory RNA. Mol Microbiol (2010) 1.02
Novel type of specialized transduction for CTX phi or its satellite phage RS1 mediated by filamentous phage VGJ phi in Vibrio cholerae. J Bacteriol (2003) 0.98
First chromosomal restriction map of Actinobacillus pleuropneumoniae and localization of putative virulence-associated genes. J Bacteriol (1999) 0.98
TagA is a secreted protease of Vibrio cholerae that specifically cleaves mucin glycoproteins. Microbiology (2010) 0.97
Genome sequencing reveals unique mutations in characteristic metabolic pathways and the transfer of virulence genes between V. mimicus and V. cholerae. PLoS One (2011) 0.96
Occurrence of Vibrio cholerae serogroups other than O1 and O139 in Austria. Wien Klin Wochenschr (2007) 0.96
The Vibrio cholerae cytolysin promotes chloride secretion from intact human intestinal mucosa. PLoS One (2009) 0.96
Basic local alignment search tool. J Mol Biol (1990) 659.07
Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase. Science (1988) 220.77
A comprehensive set of sequence analysis programs for the VAX. Nucleic Acids Res (1984) 181.98
A small cosmid for efficient cloning of large DNA fragments. Gene (1980) 22.61
Use of phoA gene fusions to identify a pilus colonization factor coordinately regulated with cholera toxin. Proc Natl Acad Sci U S A (1987) 15.50
Lysogenic conversion by a filamentous phage encoding cholera toxin. Science (1996) 15.37
A genetic locus of enterocyte effacement conserved among diverse enterobacterial pathogens. Proc Natl Acad Sci U S A (1995) 12.79
Role of a peptide tagging system in degradation of proteins synthesized from damaged messenger RNA. Science (1996) 11.15
Pathogenicity islands of virulent bacteria: structure, function and impact on microbial evolution. Mol Microbiol (1997) 9.50
Toxin, toxin-coregulated pili, and the toxR regulon are essential for Vibrio cholerae pathogenesis in humans. J Exp Med (1988) 9.19
Identification of a virulence locus encoding a second type III secretion system in Salmonella typhimurium. Proc Natl Acad Sci U S A (1996) 6.42
Regulatory cascade controls virulence in Vibrio cholerae. Proc Natl Acad Sci U S A (1991) 6.29
An inducible bundle-forming pilus of enteropathogenic Escherichia coli. Science (1991) 6.25
Excision of large DNA regions termed pathogenicity islands from tRNA-specific loci in the chromosome of an Escherichia coli wild-type pathogen. Infect Immun (1994) 5.56
Large outbreak of clinical cholera due to Vibrio cholerae non-O1 in Bangladesh. Lancet (1993) 5.48
Loss of the pigmentation phenotype in Yersinia pestis is due to the spontaneous deletion of 102 kb of chromosomal DNA which is flanked by a repetitive element. Mol Microbiol (1992) 4.41
A 40 kb chromosomal fragment encoding Salmonella typhimurium invasion genes is absent from the corresponding region of the Escherichia coli K-12 chromosome. Mol Microbiol (1995) 4.13
Two pathogenicity islands in uropathogenic Escherichia coli J96: cosmid cloning and sample sequencing. Infect Immun (1996) 3.89
Co-ordinate expression of virulence genes by ToxR in Vibrio cholerae. Mol Microbiol (1992) 3.89
A tRNA-like structure is present in 10Sa RNA, a small stable RNA from Escherichia coli. Proc Natl Acad Sci U S A (1994) 3.74
An enterotoxin produced by noncholera vibrios. Johns Hopkins Med J (1972) 3.54
The sixth and seventh cholera pandemics are due to independent clones separately derived from environmental, nontoxigenic, non-O1 Vibrio cholerae. J Bacteriol (1995) 3.44
A unique signature identifies a family of zinc-dependent metallopeptidases. FEBS Lett (1989) 3.41
Isolation of nonagglutinable vibrios from an enteritis outbreak in Czechoslovakia. J Infect Dis (1968) 3.26
A role for bacteriophages in the evolution and transfer of bacterial virulence determinants. Mol Microbiol (1995) 3.24
Genetic and DNA sequence analysis of the kanamycin resistance transposon Tn903. Proc Natl Acad Sci U S A (1980) 3.19
Deletions of chromosomal regions coding for fimbriae and hemolysins occur in vitro and in vivo in various extraintestinal Escherichia coli isolates. Microb Pathog (1990) 3.18
Safe, live Vibrio cholerae vaccines? Vaccine (1988) 2.74
Phase variation in tcpH modulates expression of the ToxR regulon in Vibrio cholerae. Mol Microbiol (1997) 2.71
A putative integrase gene defines the distal end of a large cluster of ToxR-regulated colonization genes in Vibrio cholerae. Microbiology (1996) 2.52
TcpA pilin sequences and colonization requirements for O1 and O139 vibrio cholerae. Mol Microbiol (1994) 2.25
Pathogenicity island sequences of pyelonephritogenic Escherichia coli CFT073 are associated with virulent uropathogenic strains. Infect Immun (1997) 2.21
Enteropathogenic Escherichia coli: identification of a gene cluster coding for bundle-forming pilus morphogenesis. J Bacteriol (1996) 2.08
Organization of tcp, acf, and toxT genes within a ToxT-dependent operon. Mol Microbiol (1995) 1.87
The Vibrio cholerae toxin-coregulated-pilus gene tcpI encodes a homolog of methyl-accepting chemotaxis proteins. Infect Immun (1994) 1.75
Molecular evolution of the seventh-pandemic clone of Vibrio cholerae and its relationship to other pandemic and epidemic V. cholerae isolates. J Bacteriol (1994) 1.72
Expression of the Vibrio cholerae gene encoding aldehyde dehydrogenase is under control of ToxR, the cholera toxin transcriptional activator. J Bacteriol (1991) 1.67
Identification of a gene encoding a bacteriophage-related integrase in a vap region of the Dichelobacter nodosus genome. Gene (1995) 1.45
Molecular characterization of a genomic region associated with virulence in Dichelobacter nodosus. Infect Immun (1992) 1.29
Dynamics of the bacterial genome: deletions and integrations as mechanisms of bacterial virulence modulation. Zentralbl Bakteriol (1993) 1.12
Iron transport genes of the pJM1-mediated iron uptake system of Vibrio anguillarum are included in a transposonlike structure. Plasmid (1995) 1.06
Identification of a Vibrio cholerae ToxR-activated gene (tagD) that is physically linked to the toxin-coregulated pilus (tcp) gene cluster. Gene (1994) 1.03
Isolation and characterization of a Vibrio cholerae gene (tagA) that encodes a ToxR-regulated lipoprotein. Gene (1995) 1.01
Diarrheagenic Escherichia coli. Clin Microbiol Rev (1998) 30.09
Construction of an eae deletion mutant of enteropathogenic Escherichia coli by using a positive-selection suicide vector. Infect Immun (1991) 15.39
A genetic locus of enteropathogenic Escherichia coli necessary for the production of attaching and effacing lesions on tissue culture cells. Proc Natl Acad Sci U S A (1990) 14.22
A genetic locus of enterocyte effacement conserved among diverse enterobacterial pathogens. Proc Natl Acad Sci U S A (1995) 12.79
Estimation of the warfarin dose with clinical and pharmacogenetic data. N Engl J Med (2009) 12.63
Pathogenicity islands and the evolution of microbes. Annu Rev Microbiol (2000) 9.51
The diarrheal response of humans to some classic serotypes of enteropathogenic Escherichia coli is dependent on a plasmid encoding an enteroadhesiveness factor. J Infect Dis (1985) 9.18
A DNA probe to identify enterohemorrhagic Escherichia coli of O157:H7 and other serotypes that cause hemorrhagic colitis and hemolytic uremic syndrome. J Infect Dis (1987) 8.19
Detection of an adherence factor of enteropathogenic Escherichia coli with a DNA probe. J Infect Dis (1985) 7.78
Factors associated with mortality in feedlot cattle: the Bruce County Beef Cattle Project. Can J Comp Med (1980) 7.74
New knowledge on pathogenesis of bacterial enteric infections as applied to vaccine development. Microbiol Rev (1983) 7.16
Patterns of adherence of diarrheagenic Escherichia coli to HEp-2 cells. Pediatr Infect Dis J (1987) 7.15
Plasmid-mediated adhesion in enteropathogenic Escherichia coli. J Pediatr Gastroenterol Nutr (1983) 6.59
Enteropathogenic Escherichia coli contains a putative type III secretion system necessary for the export of proteins involved in attaching and effacing lesion formation. Proc Natl Acad Sci U S A (1995) 6.59
The complete sequence of the locus of enterocyte effacement (LEE) from enteropathogenic Escherichia coli E2348/69. Mol Microbiol (1998) 6.38
Molecular epidemiology of Vibrio cholerae in the U.S. Gulf Coast. J Clin Microbiol (1982) 6.34
Enteropathogenic and enterohaemorrhagic Escherichia coli: more subversive elements. Mol Microbiol (1998) 6.12
Cloning and characterization of the eae gene of enterohaemorrhagic Escherichia coli O157:H7. Mol Microbiol (1992) 6.09
The eae gene of enteropathogenic Escherichia coli encodes a 94-kilodalton membrane protein, the expression of which is influenced by the EAF plasmid. Infect Immun (1991) 5.75
Enteropathogenic Escherichia coli. Infect Immun (1992) 5.74
A cloned pathogenicity island from enteropathogenic Escherichia coli confers the attaching and effacing phenotype on E. coli K-12. Mol Microbiol (1997) 5.55
Plasmid-mediated factors conferring diffuse and localized adherence of enteropathogenic Escherichia coli. Infect Immun (1985) 5.42
Characterization of enteroadherent-aggregative Escherichia coli, a putative agent of diarrheal disease. J Infect Dis (1988) 5.30
A second chromosomal gene necessary for intimate attachment of enteropathogenic Escherichia coli to epithelial cells. J Bacteriol (1993) 5.02
Multiple independent origins of Shigella clones of Escherichia coli and convergent evolution of many of their characteristics. Proc Natl Acad Sci U S A (2000) 4.96
Structure and sequence of the rfb (O antigen) gene cluster of Salmonella serovar typhimurium (strain LT2). Mol Microbiol (1991) 4.76
Construction and analysis of TnphoA mutants of enteropathogenic Escherichia coli unable to invade HEp-2 cells. Infect Immun (1990) 4.72
Use of pharmacogenetic and clinical factors to predict the therapeutic dose of warfarin. Clin Pharmacol Ther (2008) 4.54
Role of the eaeA gene in experimental enteropathogenic Escherichia coli infection. J Clin Invest (1993) 4.53
Enteroaggregative Escherichia coli associated with persistent diarrhea in a cohort of rural children in India. J Infect Dis (1989) 4.52
Role of plasmid-encoded adherence factors in adhesion of enteropathogenic Escherichia coli to HEp-2 cells. Infect Immun (1987) 4.48
Molecular characterization of environmental and nontoxigenic strains of Vibrio cholerae. Infect Immun (1981) 4.45
Volunteer studies of deletion mutants of Vibrio cholerae O1 prepared by recombinant techniques. Infect Immun (1988) 4.44
A sensitive and specific DNA probe to identify enteroaggregative Escherichia coli, a recently discovered diarrheal pathogen. J Infect Dis (1990) 4.43
Quorum sensing controls expression of the type III secretion gene transcription and protein secretion in enterohemorrhagic and enteropathogenic Escherichia coli. Proc Natl Acad Sci U S A (1999) 4.42
Factors associated with mortality and treatment costs in feedlot calves: the Bruce County Beef Project, years 1978, 1979, 1980. Can J Comp Med (1982) 4.34
Molecular evolution of a pathogenicity island from enterohemorrhagic Escherichia coli O157:H7. Infect Immun (1998) 4.33
Vibrio parahaemolyticus and related halophilic Vibrios. Crit Rev Microbiol (1982) 4.24
Factors associated with morbidity and mortality in feedlot calves: the Bruce County beef project, year two. Can J Comp Med (1981) 4.17
Safety, immunogenicity, and efficacy of recombinant live oral cholera vaccines, CVD 103 and CVD 103-HgR. Lancet (1988) 4.12
The Per regulon of enteropathogenic Escherichia coli : identification of a regulatory cascade and a novel transcriptional activator, the locus of enterocyte effacement (LEE)-encoded regulator (Ler). Mol Microbiol (1999) 4.12
The role of the eae gene of enterohemorrhagic Escherichia coli in intimate attachment in vitro and in a porcine model. J Clin Invest (1993) 4.11
Evolutionary relationships among pathogenic and nonpathogenic Escherichia coli strains inferred from multilocus enzyme electrophoresis and mdh sequence studies. Infect Immun (1997) 3.97
A plasmid-encoded type IV fimbrial gene of enteropathogenic Escherichia coli associated with localized adherence. Mol Microbiol (1992) 3.93
A bacteriophage encoding a pathogenicity island, a type-IV pilus and a phage receptor in cholera bacteria. Nature (1999) 3.89
Cytoskeletal composition of attaching and effacing lesions associated with enteropathogenic Escherichia coli adherence to HeLa cells. Infect Immun (1992) 3.82
Enterococci resistant to multiple antimicrobial agents, including vancomycin. Establishment of endemicity in a university medical center. Ann Intern Med (1995) 3.77
A plasmid-encoded regulatory region activates chromosomal eaeA expression in enteropathogenic Escherichia coli. Infect Immun (1995) 3.77
Clinical Pharmacogenetics Implementation Consortium guidelines for cytochrome P450-2C19 (CYP2C19) genotype and clopidogrel therapy. Clin Pharmacol Ther (2011) 3.53
Organization of the Escherichia coli K-12 gene cluster responsible for production of the extracellular polysaccharide colanic acid. J Bacteriol (1996) 3.51
Enteric bacterial toxins: mechanisms of action and linkage to intestinal secretion. Microbiol Rev (1996) 3.46
The sixth and seventh cholera pandemics are due to independent clones separately derived from environmental, nontoxigenic, non-O1 Vibrio cholerae. J Bacteriol (1995) 3.44
Quorum sensing is a global regulatory mechanism in enterohemorrhagic Escherichia coli O157:H7. J Bacteriol (2001) 3.43
Vibrio cholerae produces a second enterotoxin, which affects intestinal tight junctions. Proc Natl Acad Sci U S A (1991) 3.43
Cloning and sequencing of the genes encoding Escherichia coli cytolethal distending toxin. Infect Immun (1994) 3.36
The locus of enterocyte effacement (LEE)-encoded regulator controls expression of both LEE- and non-LEE-encoded virulence factors in enteropathogenic and enterohemorrhagic Escherichia coli. Infect Immun (2000) 3.20
Use of DNA probes and HEp-2 cell adherence assay to detect diarrheagenic Escherichia coli. J Infect Dis (1988) 3.19
Plasmid and chromosomal elements involved in the pathogenesis of attaching and effacing Escherichia coli. Infect Immun (1991) 3.13
Effect of pravastatin on outcomes after cardiac transplantation. N Engl J Med (1995) 3.11
Recombinant nontoxinogenic Vibrio cholerae strains as attenuated cholera vaccine candidates. Nature (1984) 3.08
Detection of the thermostable direct hemolysin gene and related DNA sequences in Vibrio parahaemolyticus and other vibrio species by the DNA colony hybridization test. Infect Immun (1985) 2.90
Thermostable direct hemolysin gene of Vibrio parahaemolyticus: a virulence gene acquired by a marine bacterium. Infect Immun (1995) 2.81
Accessory cholera enterotoxin (Ace), the third toxin of a Vibrio cholerae virulence cassette. Proc Natl Acad Sci U S A (1993) 2.81
Interactions between enteropathogenic Escherichia coli and host epithelial cells. Trends Microbiol (1997) 2.73
Clinical Pharmacogenetics Implementation Consortium guidelines for CYP2C19 genotype and clopidogrel therapy: 2013 update. Clin Pharmacol Ther (2013) 2.73
Escherichia coli K12 regains its O antigen. Microbiology (1994) 2.71
The role of the eaeA gene in diarrhea and neurological complications in a gnotobiotic piglet model of enterohemorrhagic Escherichia coli infection. Infect Immun (1995) 2.69
Nucleotide sequence of the thermostable direct hemolysin gene of Vibrio parahaemolyticus. J Bacteriol (1985) 2.66
In vitro activity of LY333328, an investigational glycopeptide antibiotic, against enterococci and staphylococci. Antimicrob Agents Chemother (1996) 2.63
Virulence factors in Shiga-like toxin-producing Escherichia coli isolated from humans and cattle. J Infect Dis (1992) 2.62
Characterization of interactions of enteropathogenic Escherichia coli O127:H6 with mammalian cells in vitro. J Infect Dis (1991) 2.53
Nucleotide sequences of the gnd genes from nine natural isolates of Escherichia coli: evidence of intragenic recombination as a contributing factor in the evolution of the polymorphic gnd locus. J Bacteriol (1991) 2.53
Localization of a determinant for HEp-2 adherence by enteropathogenic Escherichia coli. Infect Immun (1986) 2.52
Repeat unit polysaccharides of bacteria: a model for polymerization resembling that of ribosomes and fatty acid synthetase, with a novel mechanism for determining chain length. Mol Microbiol (1993) 2.52
Diffuse-adhering Escherichia coli (DAEC) as a putative cause of diarrhea in Mayan children in Mexico. J Infect Dis (1991) 2.52
Distribution of the bundle-forming pilus structural gene (bfpA) among enteropathogenic Escherichia coli. J Infect Dis (1993) 2.50
Secretion of extracellular proteins by enterohemorrhagic Escherichia coli via a putative type III secretion system. Infect Immun (1996) 2.47
Cloning of the cytotoxin-hemolysin gene of Vibrio vulnificus. Infect Immun (1985) 2.42
Aeromonas hydrophila: ecology and toxigenicity of isolates from an estuary. J Appl Bacteriol (1981) 2.42
Role of intimin and bundle-forming pili in enteropathogenic Escherichia coli adhesion to pediatric intestinal tissue in vitro. Infect Immun (1998) 2.41
The Pharmacogenomics Research Network Translational Pharmacogenetics Program: overcoming challenges of real-world implementation. Clin Pharmacol Ther (2013) 2.39
Role of micF in the tolC-mediated regulation of OmpF, a major outer membrane protein of Escherichia coli K-12. J Bacteriol (1987) 2.39
Molecular cloning and expression in Escherichia coli K-12 of the O antigens of the Inaba and Ogawa serotypes of the Vibrio cholerae O1 lipopolysaccharides and their potential for vaccine development. Infect Immun (1986) 2.36
Enterotoxigenicity of Vibrio parahaemolyticus with and without genes encoding thermostable direct hemolysin. Infect Immun (1992) 2.35
Morphological studies on fimbriae expressed by Vibrio cholerae 01. Microb Pathog (1988) 2.33
Childhood cancer and ethnic group in Britain: a United Kingdom children's Cancer Study Group (UKCCSG) study. Br J Cancer (1991) 2.33
Molecular characterization of Streptococcus pneumoniae type 4, 6B, 8, and 18C capsular polysaccharide gene clusters. Infect Immun (2001) 2.28
Visceral fat and race-dependent health risks in obese nondiabetic premenopausal women. Diabetes (1997) 2.26
The capsule and O antigen in Vibrio cholerae O139 Bengal are associated with a genetic region not present in Vibrio cholerae O1. Infect Immun (1995) 2.25
Practice-based research: lessons from community pharmacist participants. Pharmacotherapy (2001) 2.23
Organization of Escherichia coli O157 O antigen gene cluster and identification of its specific genes. Infect Immun (1998) 2.23
Nucleotide sequence analysis of the A2 and B subunits of Vibrio cholerae enterotoxin. J Biol Chem (1983) 2.20
The Vibrio cholerae genome contains two unique circular chromosomes. Proc Natl Acad Sci U S A (1998) 2.18
Cloning of a gene (zot) encoding a new toxin produced by Vibrio cholerae. Infect Immun (1992) 2.18
The pharmacogenetics research network: from SNP discovery to clinical drug response. Clin Pharmacol Ther (2007) 2.18
Vibrio cholerae O1 can assume a chlorine-resistant rugose survival form that is virulent for humans. J Infect Dis (1996) 2.17
Zonula occludens toxin modulates tight junctions through protein kinase C-dependent actin reorganization, in vitro. J Clin Invest (1995) 2.14