Published in Infect Immun on April 01, 1998
TLR4 signaling is coupled to SRC family kinase activation, tyrosine phosphorylation of zonula adherens proteins, and opening of the paracellular pathway in human lung microvascular endothelia. J Biol Chem (2008) 1.55
Modulation of brain hemichannels and gap junction channels by pro-inflammatory agents and their possible role in neurodegeneration. Antioxid Redox Signal (2009) 1.34
TRAF6 protein couples Toll-like receptor 4 signaling to Src family kinase activation and opening of paracellular pathway in human lung microvascular endothelia. J Biol Chem (2012) 0.90
Effects of lipopolysaccharide and Mannheimia haemolytica leukotoxin on bovine lung microvascular endothelial cells and alveolar epithelial cells. Clin Vaccine Immunol (2007) 0.85
Structure and function of lipopolysaccharide binding protein. Science (1990) 7.76
A new and improved microassay to determine 2-keto-3-deoxyoctonate in lipopolysaccharide of Gram-negative bacteria. Anal Biochem (1978) 7.69
Bacterial endotoxin: molecular relationships of structure to activity and function. FASEB J (1994) 5.70
Binding of polymyxin B to the lipid A portion of bacterial lipopolysaccharides. Immunochemistry (1976) 5.43
Septic shock in humans. Advances in the understanding of pathogenesis, cardiovascular dysfunction, and therapy. Ann Intern Med (1990) 5.15
Soluble CD14 participates in the response of cells to lipopolysaccharide. J Exp Med (1992) 4.02
Septic shock: pathogenesis. Lancet (1991) 3.99
Endotoxin and lung injury. Am Rev Respir Dis (1986) 3.20
In vivo protection against endotoxin by plasma high density lipoprotein. Proc Natl Acad Sci U S A (1993) 2.39
Crystal structure of an endotoxin-neutralizing protein from the horseshoe crab, Limulus anti-LPS factor, at 1.5 A resolution. EMBO J (1993) 2.15
Low-density lipoprotein receptor-deficient mice are protected against lethal endotoxemia and severe gram-negative infections. J Clin Invest (1996) 2.03
Lipopolysaccharide induces activation of CD14-associated protein tyrosine kinase p53/56lyn. J Biol Chem (1993) 1.95
Recognition of endotoxin by cells leading to transmembrane signaling. Curr Opin Immunol (1994) 1.67
Inactivation of endotoxin by polymyxin B. Antimicrob Agents Chemother (1974) 1.66
Direct effects of E coli endotoxin on structure and permeability of pulmonary endothelial monolayers and the endothelial layer of intimal explants. Am J Pathol (1986) 1.54
Lipopolysaccharide-induced protein tyrosine phosphorylation in human macrophages is mediated by CD14. J Immunol (1993) 1.44
Competition between bactericidal/permeability-increasing protein and lipopolysaccharide-binding protein for lipopolysaccharide binding to monocytes. J Infect Dis (1993) 1.09
Bacterial lipopolysaccharide induces actin reorganization, intercellular gap formation, and endothelial barrier dysfunction in pulmonary vascular endothelial cells: concurrent F-actin depolymerization and new actin synthesis. J Cell Physiol (1993) 1.08
Lipopolysaccharide (LPS)-binding protein and soluble CD14 function as accessory molecules for LPS-induced changes in endothelial barrier function, in vitro. J Clin Invest (1994) 1.05
Isolation and biological activities of limulus anticoagulant (anti-LPS factor) which interacts with lipopolysaccharide (LPS). J Biochem (1985) 1.04
Binding and neutralization of endotoxin by Limulus antilipopolysaccharide factor. Infect Immun (1992) 0.96
Endotoxin induces endothelial barrier dysfunction through protein tyrosine phosphorylation. Am J Physiol (1997) 0.95
Primary structure of anti-lipopolysaccharide factor from American horseshoe crab, Limulus polyphemus. J Biochem (1987) 0.95
Protective effects of a recombinant amino-terminal fragment of human bactericidal/permeability-increasing protein in an animal model of gram-negative sepsis. J Infect Dis (1995) 0.91
Current understanding of the pathogenesis of gram-negative shock. Infect Dis Clin North Am (1991) 0.88
Limulus antilipopolysaccharide factor protects rabbits from meningococcal endotoxin shock. J Infect Dis (1992) 0.88
Peptide derivatives of three distinct lipopolysaccharide binding proteins inhibit lipopolysaccharide-induced tumor necrosis factor-alpha secretion in vitro. Surgery (1995) 0.87
Endotoxin neutralization with rabbit antisera to Escherichia coli J5 and other gram-negative bacteria. Infect Immun (1987) 0.85
Lipopolysaccharide detoxification by endotoxin neutralizing protein. J Surg Res (1993) 0.84
Antilipopolysaccharide factor from horseshoe crab, Tachypleus tridentatus, inhibits lipopolysaccharide activation of cultured human endothelial cells. Infect Immun (1989) 0.83
Structure and functions of endotoxin-binding peptides derived from CAP18. Prog Clin Biol Res (1995) 0.81
Determination of bacterial number and biomass in the marine environment. Appl Environ Microbiol (1977) 27.80
Capsular polysaccharides of Cryptococcus neoformans. Rev Infect Dis (1984) 3.10
Human neutrophils increase expression of C3bi as well as C3b receptors upon activation. J Clin Invest (1984) 2.88
Zonulin, a newly discovered modulator of intestinal permeability, and its expression in coeliac disease. Lancet (2000) 2.82
The K1 capsule is the critical determinant in the development of Escherichia coli meningitis in the rat. J Clin Invest (1992) 2.66
Structural determination of the sialic acid polysaccharide antigens of Neisseria meningitidis serogroups B and C with carbon 13 nuclear magnetic resonance. J Biol Chem (1975) 2.51
Lung myeloperoxidase as a measure of pulmonary leukostasis in rabbits. J Appl Physiol (1985) (1985) 2.40
The importance of the K1 capsule in invasive infections caused by Escherichia coli. J Infect Dis (1984) 2.14
Zonula occludens toxin modulates tight junctions through protein kinase C-dependent actin reorganization, in vitro. J Clin Invest (1995) 2.14
Evidence for the role of toxin A in the pathogenesis of infection with Pseudomonas aeruginosa in humans. J Infect Dis (1980) 1.90
A surface polysaccharide of Escherichia coli O111 contains O-antigen and inhibits agglutination of cells by O-antiserum. J Bacteriol (1982) 1.84
Human zonulin, a potential modulator of intestinal tight junctions. J Cell Sci (2000) 1.78
Structural studies on the major, capsular polysaccharide from Cryptococcus bacillisporus serotype B. Carbohydr Res (1980) 1.74
Evaluation of immunotherapeutic approaches for the potential treatment of infections caused by K1-positive Escherichia coli. J Infect Dis (1983) 1.73
Cerebral mucormycosis associated with intravenous drug use: three case reports and review. Clin Infect Dis (1994) 1.73
Role of lipopolysaccharide and capsule in the serum resistance of bacteremic strains of Escherichia coli. J Infect Dis (1986) 1.73
A morphological and immunocytochemical study of a distinctive variant of ductal carcinoma in-situ of the breast. Histopathology (1985) 1.67
On the structure of the capsular polysaccharide from Cryptococcus neoformans serotype C. Immunochemistry (1978) 1.66
Febrile core temperature is essential for optimal host defense in bacterial peritonitis. Infect Immun (2000) 1.64
Antiendotoxin antibodies: a dead end? Ann Intern Med (1994) 1.57
Anthrax edema toxin differentially regulates lipopolysaccharide-induced monocyte production of tumor necrosis factor alpha and interleukin-6 by increasing intracellular cyclic AMP. Infect Immun (1994) 1.57
Host defenses and immunologic alterations associated with chronic hemodialysis. Ann Intern Med (1980) 1.54
The R-type lipopolysaccharides of Neisseria meningitidis. Can J Biochem (1980) 1.52
Structural determination of the polysaccharide antigens of Neisseria meningitidis serogroups Y, W-135, and BO1. Can J Biochem (1976) 1.52
Measuring difficult temperament the easy way. J Dev Behav Pediatr (2000) 1.50
Concepts of fever: recent advances and lingering dogma. Clin Infect Dis (1997) 1.50
Inflammatory cytokines produced in response to experimental human gonorrhea. J Infect Dis (1995) 1.49
Capsular polysaccharides from a parent strain and from a possible, mutant strain of Cryptococcus neoformans serotype A. Carbohydr Res (1981) 1.48
Bacterial lipopolysaccharide disrupts endothelial monolayer integrity and survival signaling events through caspase cleavage of adherens junction proteins. J Biol Chem (1998) 1.43
Altered cytokine regulation in the lungs of cigarette smokers. Am J Respir Crit Care Med (1994) 1.41
The structure of the capsular polysaccharide from Cryptococcus neoformans serotype D. Carbohydr Res (1979) 1.41
Effect of race and blood group on the immune response to bacterial polysaccharide and conjugate vaccines. Lancet (1990) 1.41
Inhibition of tumor necrosis factor-alpha transcription in macrophages exposed to febrile range temperature. A possible role for heat shock factor-1 as a negative transcriptional regulator. J Biol Chem (2000) 1.40
Cholera-like toxic effect of culture filtrates of Escherichia coli. J Infect Dis (1974) 1.40
Effects of opsonization and gamma interferon on growth of Brucella melitensis 16M in mouse peritoneal macrophages in vitro. Infect Immun (2000) 1.36
Safety and immunogenicity of a Pseudomonas aeruginosa O-polysaccharide toxin A conjugate vaccine in humans. J Clin Invest (1987) 1.33
Experimental human gonococcal urethritis: 250 Neisseria gonorrhoeae MS11mkC are infective. J Infect Dis (1995) 1.32
Turbidimetric method for quantifying serum inhibition of Limulus amoebocyte lysate. J Clin Microbiol (1985) 1.30
The presence of K54 capsular polysaccharide increases the pathogenicity of Escherichia coli in vivo. J Infect Dis (1994) 1.29
Labor and infection. II. Bacterial endotoxin in amniotic fluid and its relationship to the onset of preterm labor. Am J Obstet Gynecol (1988) 1.29
Direct effects of endotoxin on the endothelium: barrier function and injury. Lab Invest (1999) 1.27
Strucutres of the capsular polysaccharides of Neisseria meningitidis as determined by 13C-nuclear magnetic resonance spectroscopy. J Infect Dis (1977) 1.25
Neutralization of bacterial lipopolysaccharides by human plasma. J Clin Microbiol (1985) 1.25
Structural elucidation of the 3-deoxy-D-manno-octulosonic acid containing meningococcal 29-e capsular polysaccharide antigen using carbon-13 nuclear magnetic resonance. Biochemistry (1978) 1.24
On the structure of the capsular polysaccharide from Cryptococcus neoformans serotype C--II. Mol Immunol (1979) 1.24
Galactofuranosyl groups are immunodominant in Aspergillus fumigatus galactomannan. Mol Immunol (1985) 1.23
Role of respiratory assistance devices in endemic nosocomial pneumonia. Am J Med (1981) 1.22
Aerobactin and alpha-hemolysin as virulence determinants in Escherichia coli isolated from human blood, urine, and stool. J Infect Dis (1990) 1.22
Calcium requirements for increased complement receptor expression during neutrophil activation. J Immunol (1985) 1.21
Immunoprophylaxis against klebsiella and pseudomonas aeruginosa infections. The Federal Hyperimmune Immunoglobulin Trial Study Group. J Infect Dis (1996) 1.21
Sensitivity of K1-encapsulated Escherichia coli to killing by the bactericidal/permeability-increasing protein of rabbit and human neutrophils. Infect Immun (1982) 1.19
Functional activities of monoclonal antibodies to the O side chain of Escherichia coli lipopolysaccharides in vitro and in vivo. J Infect Dis (1988) 1.19
Differential induction of tumor necrosis factor by bacteria expressing rough and smooth lipopolysaccharide phenotypes. Infect Immun (1991) 1.19
Diphtheria: the patch remains. J Laryngol Otol (2003) 1.18
Stimulation of polymorphonuclear leukocyte bactericidal activity by supernatants of activated human mononuclear cells. Infect Immun (1978) 1.18
Polysaccharide capsule-mediated resistance to opsonophagocytosis in Klebsiella pneumoniae. Infect Immun (1994) 1.17
O-antigen seroepidemiology of Klebsiella clinical isolates and implications for immunoprophylaxis of Klebsiella infections. Clin Diagn Lab Immunol (1997) 1.17
Increased activity of interleukin-6 but not tumor necrosis factor-alpha in lung lavage of premature infants is associated with the development of bronchopulmonary dysplasia. Pediatr Res (1994) 1.17
Gamma interferon augments macrophage activation by lipopolysaccharide by two distinct mechanisms, at the signal transduction level and via an autocrine mechanism involving tumor necrosis factor alpha and interleukin-1. Infect Immun (1999) 1.15
Covalent polymyxin B conjugate with human immunoglobulin G as an antiendotoxin reagent. Antimicrob Agents Chemother (1998) 1.14
Lymphoblastoid cell supernatants increase expression of C3b receptors on human polymorphonuclear leucocytes: direct binding studies with 125I-C3b. Immunology (1984) 1.14
Ureaplasma urealyticum modulates endotoxin-induced cytokine release by human monocytes derived from preterm and term newborns and adults. Infect Immun (2001) 1.13
Effects of hypothermia and hyperthermia on cytokine production by cultured human mononuclear phagocytes from adults and newborns. J Interferon Cytokine Res (2000) 1.13
Clinical trials for severe sepsis. Past failures, and future hopes. Infect Dis Clin North Am (1999) 1.12
The role of 3' poly(A) tail metabolism in tumor necrosis factor-alpha regulation. J Biol Chem (1997) 1.12
Infective endocarditis and access site infections in patients on hemodialysis. Medicine (Baltimore) (1976) 1.11
Differential effects of hyperthermia on macrophage interleukin-6 and tumor necrosis factor-alpha expression. Am J Physiol (1994) 1.11
Impaired control of Brucella melitensis infection in Rag1-deficient mice. Infect Immun (2000) 1.11
Immunogenicity of a 24-valent Klebsiella capsular polysaccharide vaccine and an eight-valent Pseudomonas O-polysaccharide conjugate vaccine administered to victims of acute trauma. Clin Infect Dis (1996) 1.10
Protection of mice against brucellosis by vaccination with Brucella melitensis WR201(16MDeltapurEK). Infect Immun (1999) 1.09
Febrile-range temperature modifies early systemic tumor necrosis factor alpha expression in mice challenged with bacterial endotoxin. Infect Immun (1999) 1.09
Exposure to febrile temperature upregulates expression of pyrogenic cytokines in endotoxin-challenged mice. Am J Physiol (1999) 1.09
Sensitivity of Limulus amebocyte lysate (LAL) to LAL-reactive glucans. J Clin Microbiol (1991) 1.08
Utility of alkylaminoquinolinyl methanols as new antimalarial drugs. Antimicrob Agents Chemother (2006) 1.08
Efficacy of a monoclonal antibody directed against tumor necrosis factor in protecting neutropenic rats from lethal infection with Pseudomonas aeruginosa. J Infect Dis (1990) 1.07
Over-expression of hsp-70 inhibits bacterial lipopolysaccharide-induced production of cytokines in human monocyte-derived macrophages. Cytokine (2001) 1.06
Structural specificity of chloroquine-hematin binding related to inhibition of hematin polymerization and parasite growth. J Med Chem (1999) 1.05
Characteristics of the serum vibriocidal and agglutinating antibodies in cholera cases and in normal residents of the endemic and non-endemic cholera areas. J Immunol (1970) 1.05
Inflammatory cytokine mRNAs in surgical specimens of necrotizing enterocolitis and normal newborn intestine. Pediatr Pathol Lab Med (1997) 1.04
Monoclonal antibody against Klebsiella capsular polysaccharide reduces severity and hematogenic spread of experimental Klebsiella pneumoniae pneumonia. Infect Immun (1992) 1.04
Modulation of blood-brain barrier permeability by tumor necrosis factor and antibody to tumor necrosis factor in the rat. Lymphokine Cytokine Res (1992) 1.04
Active immunization with a detoxified Escherichia coli J5 lipopolysaccharide group B meningococcal outer membrane protein complex vaccine protects animals from experimental sepsis. J Infect Dis (2001) 1.04
Pulmonary mechanics after uncomplicated influenza A infection. Am Rev Respir Dis (1976) 1.03
A double-blind clinical trial in weight control. Use of fenfluramine and phentermine alone and in combination. Arch Intern Med (1984) 1.03
Assay of endotoxin by limulus amebocyte lysate. Methods Mol Med (2000) 1.02
Nocturnal increase of urinary uric acid:creatinine ratio. A biochemical correlate of sleep-associated hypoxemia. Am Rev Respir Dis (1987) 1.02
Prevention and therapy of experimental Escherichia coli infection with monoclonal antibody. Infect Immun (1985) 1.02
Phase 1 trial of a 24-valent Klebsiella capsular polysaccharide vaccine and an eight-valent Pseudomonas O-polysaccharide conjugate vaccine administered simultaneously. Vaccine (1994) 1.00
Clostridium difficile infection is a risk factor for bacteremia due to vancomycin-resistant enterococci (VRE) in VRE-colonized patients with acute leukemia. Clin Infect Dis (1997) 1.00
Interleukin-1-induced granulocytopenia and pulmonary leukostasis in rabbits. J Appl Physiol (1985) (1987) 0.99
Outer membrane protein of Neisseria meningitidis as a mucosal adjuvant for lipopolysaccharide of Brucella melitensis in mouse and guinea pig intranasal immunization models. Infect Immun (1996) 0.99
Evaluation of surrogate markers of impending death in the galactosamine-sensitized murine model of bacterial endotoxemia. Lab Anim Sci (1999) 0.99
Production of exoenzyme S by clinical isolates of Pseudomonas aeruginosa. Infect Immun (1981) 0.99
Diarrhoea resembling cholera induced by Escherichia coli culture filtrate. Lancet (1973) 0.99
Blood-brain barrier permeability during the development of experimental bacterial meningitis in the rat. Exp Neurol (1997) 0.98