K Takio

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Top papers

Rank Title Journal Year PubWeight™‹?›
1 The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase eta. Nature 1999 10.87
2 A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death. Mol Cell 2001 4.24
3 Fission yeast condensin complex: essential roles of non-SMC subunits for condensation and Cdc2 phosphorylation of Cut3/SMC4. Genes Dev 1999 3.37
4 Purification and cloning of a nucleotide excision repair complex involving the xeroderma pigmentosum group C protein and a human homologue of yeast RAD23. EMBO J 1994 2.94
5 Amino acid sequence of human von Willebrand factor. Biochemistry 1986 2.73
6 Guanosine cyclic 3',5'-phosphate dependent protein kinase, a chimeric protein homologous with two separate protein families. Biochemistry 1984 2.62
7 Homology of amino acid sequences of rat liver cathepsins B and H with that of papain. Proc Natl Acad Sci U S A 1983 2.60
8 A novel motor, KIF13A, transports mannose-6-phosphate receptor to plasma membrane through direct interaction with AP-1 complex. Cell 2000 2.56
9 Activin-binding protein from rat ovary is follistatin. Science 1990 2.38
10 Mass spectrometry of purified amyloid beta protein in Alzheimer's disease. J Biol Chem 1992 2.26
11 The COP9 complex is conserved between plants and mammals and is related to the 26S proteasome regulatory complex. Curr Biol 1998 2.21
12 Proline-directed and non-proline-directed phosphorylation of PHF-tau. J Biol Chem 1995 2.09
13 Novel non-heme iron center of nitrile hydratase with a claw setting of oxygen atoms. Nat Struct Biol 1998 2.07
14 Identification of alpha-fodrin as a candidate autoantigen in primary Sjögren's syndrome. Science 1997 2.06
15 The growth inhibitory factor that is deficient in the Alzheimer's disease brain is a 68 amino acid metallothionein-like protein. Neuron 1991 2.05
16 Identification of the calmodulin-binding domain of skeletal muscle myosin light chain kinase. Proc Natl Acad Sci U S A 1985 2.00
17 A putative Ca2+-binding protein: structure of the light subunit of porcine calpain elucidated by molecular cloning and protein sequence analysis. Proc Natl Acad Sci U S A 1985 1.99
18 Protein sequence and mass spectrometric analyses of tau in the Alzheimer's disease brain. J Biol Chem 1992 1.89
19 Distinct intramembrane cleavage of the beta-amyloid precursor protein family resembling gamma-secretase-like cleavage of Notch. J Biol Chem 2001 1.83
20 Horse liver aldehyde dehydrogenase. Purification and characterization of two isozymes. J Biol Chem 1976 1.78
21 Amino acid sequence of the von Willebrand factor-binding domain of platelet membrane glycoprotein Ib. Proc Natl Acad Sci U S A 1987 1.73
22 Homology of perforin to the ninth component of complement (C9). Nature 1988 1.69
23 Dephosphorylation of cAMP-dependent protein kinase regulatory subunit (type II) by calmodulin-dependent protein phosphatase. Determinants of substrate specificity. J Biol Chem 1986 1.61
24 Purification and cDNA cloning of a human UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase. J Biol Chem 1995 1.60
25 Solvent accessibility of the thrombin-thrombomodulin interface. J Mol Biol 2001 1.58
26 Primary structure of the regulatory subunit of type II cAMP-dependent protein kinase from bovine cardiac muscle. Proc Natl Acad Sci U S A 1982 1.58
27 Amino acid sequence of the heat-stable inhibitor of the cAMP-dependent protein kinase from rabbit skeletal muscle. Proc Natl Acad Sci U S A 1985 1.47
28 Identification of a PDZ-domain-containing protein that interacts with the scavenger receptor class B type I. Proc Natl Acad Sci U S A 2000 1.47
29 Amino acid sequence of the beta subunit of bovine lung casein kinase II. Proc Natl Acad Sci U S A 1987 1.44
30 Molecular heterogeneity of follistatin, an activin-binding protein. Higher affinity of the carboxyl-terminal truncated forms for heparan sulfate proteoglycans on the ovarian granulosa cell. J Biol Chem 1993 1.44
31 The cAMP-binding domains of the regulatory subunit of cAMP-dependent protein kinase and the catabolite gene activator protein are homologous. Proc Natl Acad Sci U S A 1982 1.43
32 Wound-induced trypsin inhibitor in alfalfa leaves: identity as a member of the Bowman-Birk inhibitor family. Biochemistry 1985 1.36
33 Post-translational modification is essential for catalytic activity of nitrile hydratase. Protein Sci 2000 1.36
34 The crystal structure of cytochrome c peroxidase. J Biol Chem 1980 1.35
35 Amino acid sequence of the regulatory subunit of bovine type II adenosine cyclic 3',5'-phosphate dependent protein kinase. Biochemistry 1984 1.33
36 Isolation and characterization of human cDNA clones encoding the alpha and the alpha' subunits of casein kinase II. Biochemistry 1990 1.31
37 Amino acid sequence of an active fragment of rabbit skeletal muscle myosin light chain kinase. Biochemistry 1985 1.30
38 The oncofetal structure of human fibronectin defined by monoclonal antibody FDC-6. Unique structural requirement for the antigenic specificity provided by a glycosylhexapeptide. J Biol Chem 1988 1.27
39 Ubiquitin is conjugated with amino-terminally processed tau in paired helical filaments. Neuron 1993 1.25
40 In vivo phosphorylation sites in fetal and adult rat tau. J Biol Chem 1993 1.24
41 Properties and structure of spermidine acetyltransferase in Escherichia coli. J Biol Chem 1994 1.24
42 Amino acid sequence of rabbit skeletal muscle myosin light chain kinase. Biochemistry 1986 1.22
43 Characterization of two distinct monoclonal antibodies to paired helical filaments: further evidence for fetal-type phosphorylation of the tau in paired helical filaments. J Neurochem 1993 1.21
44 Primary structure study of rat liver cathepsin B -- a striking resemblance to papain. Biochem Biophys Res Commun 1980 1.20
45 Multiple copies of the proB gene enhance degS-dependent extracellular protease production in Bacillus subtilis. J Bacteriol 1994 1.20
46 Deamidation and isoaspartate formation in smeared tau in paired helical filaments. Unusual properties of the microtubule-binding domain of tau. J Biol Chem 1999 1.19
47 Hyperphosphorylation of tau in PHF. Neurobiol Aging 1995 1.18
48 Cloning and molecular characterization of plant aldehyde oxidase. J Biol Chem 1997 1.17
49 Fetal-type phosphorylation of the tau in paired helical filaments. J Neurochem 1992 1.17
50 The amino acid sequence of a hinge region in the regulatory subunit of bovine cardiac muscle cyclic AMP-dependent protein kinase II. FEBS Lett 1980 1.15
51 Cloning and functional expression of a novel glucuronyltransferase involved in the biosynthesis of the carbohydrate epitope HNK-1. Proc Natl Acad Sci U S A 1997 1.14
52 Functional expression of nitrile hydratase in Escherichia coli: requirement of a nitrile hydratase activator and post-translational modification of a ligand cysteine. J Biochem 1999 1.11
53 Amino acid sequence of the sex steroid binding protein of human blood plasma. Biochemistry 1986 1.11
54 Characterization of the calmodulin-binding and catalytic domains in skeletal muscle myosin light chain kinase. J Biol Chem 1985 1.11
55 The signal modulator protein 14-3-3 is a target of sphingosine- or N,N-dimethylsphingosine-dependent kinase in 3T3(A31) cells. Biochem Biophys Res Commun 1995 1.10
56 N-terminal sequencing of photosystem II low-molecular-mass proteins. 5 and 4.1 kDa components of the O2-evolving core complex from higher plants. FEBS Lett 1989 1.09
57 Alternatively spliced isoform of P-selectin is present in vivo as a soluble molecule. J Biol Chem 1994 1.09
58 Amino acid sequence around a "hinge" region and its "autophosphorylation" site in bovine Lung cGMP-dependent protein kinase. J Biol Chem 1983 1.09
59 Serine phospholipid-specific phospholipase A that is secreted from activated platelets. A new member of the lipase family. J Biol Chem 1997 1.07
60 Amino acid sequence at the ATP-binding site of cGMP-dependent protein kinase. J Biol Chem 1982 1.07
61 Dual amino acid-selective and site-directed stable-isotope labeling of the human c-Ha-Ras protein by cell-free synthesis. J Biomol NMR 1998 1.07
62 Purification and characterization of the yeast negative regulatory protein GAL80. J Biol Chem 1991 1.06
63 Neural cell adhesion molecule mediates contact-dependent inhibition of growth of near-diploid mouse fibroblast cell line m5S/1M. J Cell Biol 1991 1.06
64 Supernatant protein factor, which stimulates the conversion of squalene to lanosterol, is a cytosolic squalene transfer protein and enhances cholesterol biosynthesis. Proc Natl Acad Sci U S A 2001 1.06
65 Combination of biomolecular interaction analysis and mass spectrometric amino acid sequencing. Anal Chem 2000 1.04
66 Studies on the site in the regulatory subunit of type I cAMP-dependent protein kinase phosphorylated by cGMP-dependent protein kinase. J Biol Chem 1981 1.04
67 Activin-binding protein is present in pituitary. Endocrinology 1991 1.02
68 Characterization of a recombinant soluble form of human placental leucine aminopeptidase/oxytocinase expressed in Chinese hamster ovary cells. Eur J Biochem 2000 1.01
69 Amino acid sequence of sialic acid binding lectin from frog (Rana catesbeiana) eggs. Biochemistry 1987 1.01
70 Tertiary and quaternary structures of photoreactive Fe-type nitrile hydratase from Rhodococcus sp. N-771: roles of hydration water molecules in stabilizing the structures and the structural origin of the substrate specificity of the enzyme. Biochemistry 1999 0.99
71 Characterization through cDNA cloning of galactoprotein b3 (Gap b3), a cell surface membrane glycoprotein showing enhanced expression on oncogenic transformation. Identification of Gap b3 as a member of the integrin superfamily. J Biol Chem 1990 0.99
72 Purification and characterization of wild-type and mutant "classical" nitroreductases of Salmonella typhimurium. L33R mutation greatly diminishes binding of FMN to the nitroreductase of S. typhimurium. J Biol Chem 1998 0.98
73 Cobalt-substituted Fe-type nitrile hydratase of Rhodococcus sp. N-771. FEBS Lett 2000 0.98
74 Spermidine-preferential uptake system in Escherichia coli. ATP hydrolysis by PotA protein and its association with membrane. J Biol Chem 1995 0.98
75 Subunit structure of casein kinase II from bovine testis. Demonstration that the alpha and alpha' subunits are distinct polypeptides. J Biol Chem 1990 0.98
76 Three forms of thiol proteinase inhibitor from rat liver formed depending on the oxidation-reduction state of a sulfhydryl group. J Biol Chem 1984 0.96
77 CIRP2, a major cytoplasmic RNA-binding protein in Xenopus oocytes. Nucleic Acids Res 2000 0.96
78 Primary structure of yeast cytochrome c peroxidase. II. The complete amino acid sequence. Arch Biochem Biophys 1980 0.95
79 Production of homo- and hetero-dimeric isozymes from two aldehyde oxidase genes of Arabidopsis thaliana. J Biochem 1999 0.95
80 Purification, cDNA cloning, and expression of UDP-Gal: glucosylceramide beta-1,4-galactosyltransferase from rat brain. J Biol Chem 1998 0.95
81 Cell cycle-dependent interaction of Mad2 with conserved Box1/2 region of human granulocyte-macrophage colony-stimulating factor receptor common betac. J Biol Chem 2001 0.94
82 Site-specific glycosylation of bovine butyrophilin. J Biochem 1995 0.93
83 Nuclear magnetic resonance and molecular dynamics studies on the interactions of the Ras-binding domain of Raf-1 with wild-type and mutant Ras proteins. J Mol Biol 1999 0.93
84 Purification and molecular properties of yeast hemoglobin. Eur J Biochem 1973 0.93
85 Localization of the binding site of tissue-type plasminogen activator to fibrin. J Clin Invest 1986 0.92
86 Structure of the photoreactive iron center of the nitrile hydratase from Rhodococcus sp. N-771. Evidence of a novel post-translational modification in the cysteine ligand. J Biol Chem 1997 0.91
87 Molecular characterization and gene expression of lhcb5 gene encoding CP26 in the light-harvesting complex II of Chlamydomonas reinhardtii. Plant Mol Biol 2001 0.88
88 Amino acid sequence of rat liver thiol proteinase inhibitor. Biochem Biophys Res Commun 1983 0.86
89 Isolation and characterization of activin receptor from mouse embryonal carcinoma cells. Identification of its serine/threonine/tyrosine protein kinase activity. J Biol Chem 1992 0.86
90 Amino acid sequence of rat epidermal thiol proteinase inhibitor. Biochem Biophys Res Commun 1984 0.86
91 A monoclonal antibody, 3A10, recognizes a specific amino acid sequence present on a series of developmentally expressed brain proteins. J Biochem 1999 0.85
92 Structure of melittin bound to phospholipid micelles studied using hydrogen-deuterium exchange and electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry. J Am Soc Mass Spectrom 2001 0.85
93 Complete amino acid sequence of rat liver cytosolic alanine aminotransferase. Biochemistry 1991 0.84
94 Isolation and characterization of native activin B. J Biol Chem 1992 0.84
95 Characterization of the structural difference between active and inactive forms of the Ras protein by chemical modification followed by mass spectrometric peptide mapping. Anal Biochem 1997 0.84
96 Phosphorylation of Srp1p, the yeast nuclear localization signal receptor, in vitro and in vivo. Biochimie 1997 0.84
97 Microanalysis of the amino acid sequence of the eclosion hormone from the tobacco hornworm Manduca sexta. FEBS Lett 1987 0.83
98 Characterization of a novel fungal protein, p15, which induces neuronal differentiation of PC12 cells. J Biochem 1999 0.82
99 Rat liver thiol proteinases: cathepsin B, cathepsin H and cathepsin L. Acta Biol Med Ger 1981 0.82
100 Isolation and characterization of the gene encoding an aminopeptidase involved in the selective toxicity of ascamycin toward Xanthomonas campestris pv. citri. Biochem J 1996 0.82
101 Amino acid sequences of metalloendopeptidases specific for acyl-lysine bonds from Grifola frondosa and Pleurotus ostreatus fruiting bodies. J Biol Chem 1997 0.82
102 The relationship between ST6Gal I Golgi retention and its cleavage-secretion. Glycobiology 1999 0.82
103 Complete amino acid sequence of human liver cytosolic alanine aminotransferase (GPT) determined by a combination of conventional and mass spectral methods. Biochemistry 1991 0.82
104 Kinetic characterization of lysine-specific metalloendopeptidases from Grifola frondosa and Pleurotus ostreatus fruiting bodies. J Biochem 1998 0.82
105 A characteristic arrangement of aromatic amino acid residues in the solution structure of the amino-terminal RNA-binding domain of Drosophila sex-lethal. J Mol Biol 1997 0.82
106 An automated interpretation of MALDI/TOF postsource decay spectra of oligosaccharides. 1. Automated peak assignment. Anal Chem 1999 0.81
107 Isolation to homogeneity and partial characterization of a histo-blood group A defined Fuc alpha 1----2Gal alpha 1----3-N-acetylgalactosaminyltransferase from human lung tissue. J Biol Chem 1990 0.81
108 Gene cloning, expression, crystallization and preliminary X-ray analysis of Thermus thermophilus arginyl-tRNA synthetase. Acta Crystallogr D Biol Crystallogr 2001 0.80
109 Serine proteinase inhibitor 3 and murinoglobulin I are potent inhibitors of neuropsin in adult mouse brain. J Biol Chem 2001 0.80
110 Endogenous substrates of sphingosine-dependent kinases (SDKs) are chaperone proteins: heat shock proteins, glucose-regulated proteins, protein disulfide isomerase, and calreticulin. Biochemistry 1999 0.80
111 Properties of a revertant of Escherichia coli viable in the presence of spermidine accumulation: increase in L-glycerol 3-phosphate. J Bacteriol 2001 0.80
112 Isolation and characterization of Xenopus follistatin and activins. Dev Biol 1993 0.80
113 Observation of hydrogen-deuterium exchange of ubiquitin by direct analysis of electrospray capillary-skimmer dissociation with Fourier transform ion cyclotron resonance mass spectrometry. Anal Chem 1999 0.80
114 Interactions of a didomain fragment of the Drosophila sex-lethal protein with single-stranded uridine-rich oligoribonucleotides derived from the transformer and Sex-lethal messenger RNA precursors: NMR with residue-selective [5-2H]uridine substitutions. J Biomol NMR 2000 0.79
115 Racemization: its biological significance on neuropathogenesis of Alzheimer's disease. Tohoku J Exp Med 1994 0.79
116 Structural characterization of thymidine phosphorylase purified from human placenta. Biochem Biophys Res Commun 1995 0.78
117 Collision-induced dissociation spectra obtained by Fourier transform ion cyclotron resonance mass spectrometry using a 13C,15N-doubly depleted protein. Anal Chem 1998 0.78
118 Tau 2: a probe for a Ser conformation in the amino terminus of tau. J Neurochem 1992 0.78
119 Induction of manganese-superoxide dismutase in MRC-5 cells persistently infected with an alphavirus, sindbis. Biochem Biophys Res Commun 1999 0.78
120 Primary structure of yeast cytochrome c peroxidase. I. Chemical characterization of the polypeptide chain and of tryptic and chymotryptic peptides. Arch Biochem Biophys 1980 0.78
121 Purification and characterization of UDP-GlcNAc:IV3 beta Gal-Gb4Cer beta-1,6-GlcNAc transferase from mouse kidney. J Biol Chem 1994 0.77
122 Structure of a mouse immunoglobulin G that lacks the entire CH1 domain: protein sequencing and small-angle X-ray scattering studies. Biochemistry 1990 0.77
123 Structural characterization of mouse monoclonal antibody 13-1 against a porphyrin derivative: identification of a disulfide bond in CDR-H3 of Mab 13-1. Biochem Biophys Res Commun 1997 0.77
124 Purification and characterization of high molecular weight forms of inhibin from bovine follicular fluid. Endocrinology 1992 0.77
125 Molecular cloning of a novel sex pheromone responsible for the release of a different sex pheromone in Closterium peracerosum-strigosum-littorale complex. Plant Cell Physiol 1998 0.76
126 Reevaluation of the amino acid sequence of porcine follitropin. J Protein Chem 1989 0.76
127 Identification of domains on the extrinsic 33-kDa protein possibly involved in electrostatic interaction with photosystem II complex by means of chemical modification. J Biol Chem 1997 0.76
128 The complete amino acid sequences of two serine proteinase inhibitors from the fruiting bodies of a basidiomycete, Pleurotus ostreatus. Arch Biochem Biophys 1995 0.76
129 Inhibin alpha-subunit monomer is present in bovine follicular fluid. Biochem Biophys Res Commun 1989 0.76
130 Characterization of the interface structure of enzyme-inhibitor complex by using hydrogen-deuterium exchange and electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry. Protein Sci 2000 0.75
131 Molecular cloning and expression of cDNA encoding chicken UDP-N-acetyl-D-glucosamine (GlcNAc): GlcNAcbeta 1-6(GlcNAcbeta 1-2)- manalpha 1-R[GlcNAc to man]beta 1,4N-acetylglucosaminyltransferase VI. J Biol Chem 2000 0.75
132 Partial characterization of a 17 kDa acidic protein, EFP, induced by thiocarbamate in the early flowering phase in Asparagus seedlings. Plant Cell Physiol 1996 0.75
133 Purification and amino- and carboxyl-terminal amino acid sequences of alanine-glyoxylate transaminase 1 from human liver. J Biochem 1994 0.75
134 Stage-specific modification of G protein beta subunits in rat placenta. Mol Cell Endocrinol 2001 0.75
135 Isolation and characterization of calmodulin in the pheromone gland of the silkworm, Bombyx mori. Comp Biochem Physiol B Biochem Mol Biol 1998 0.75
136 Genetic studies of familial amyloid polyneuropathy in the Arao district of Japan. III. Analysis of amyloid fibril protein. Jinrui Idengaku Zasshi 1984 0.75
137 Simultaneous analyses of the effluent in chromatography of peptides with ninhydrin, Pauly and Sakaguchi reagents using an autoanalyzer. J Biochem 1967 0.75
138 A possible fetal antigen of Mr 70,000 in neurofibrillary tangles. Brain Res 1991 0.75
139 Localization of activin and follistatin proteins in the Xenopus oocyte. Biochem Biophys Res Commun 1994 0.75