Published in J Clin Invest on June 01, 1998
Angiotensin II regulates cellular immune responses through a calcineurin-dependent pathway. J Clin Invest (1999) 1.80
A novel role for type 1 angiotensin receptors on T lymphocytes to limit target organ damage in hypertension. Circ Res (2012) 1.79
Early acceptance of renal allografts in mice is dependent on foxp3(+) cells. Am J Pathol (2011) 1.23
B lymphocytes differentially influence acute and chronic allograft rejection in mice. J Immunol (2011) 0.98
Most parasite-specific CD8+ cells in Trypanosoma cruzi-infected chronic mice are down-regulated for T-cell receptor-alphabeta and CD8 molecules. Immunology (2001) 0.87
Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem (1987) 281.19
Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes. Nature (1988) 11.55
Normal development of mice deficient in beta 2M, MHC class I proteins, and CD8+ T cells. Science (1990) 8.17
Interaction of Staphylococcus aureus toxin "superantigens" with human T cells. Proc Natl Acad Sci U S A (1989) 7.48
Serial triggering of many T-cell receptors by a few peptide-MHC complexes. Nature (1995) 7.40
Primarily vascularized allografts of hearts in mice. The role of H-2D, H-2K, and non-H-2 antigens in rejection. Transplantation (1973) 6.01
T cell activation determined by T cell receptor number and tunable thresholds. Science (1996) 5.51
Antigen recognition by human T lymphocytes is linked to surface expression of the T3 molecular complex. Cell (1982) 4.86
Monoclonal antibody to murine gamma interferon inhibits lymphokine-induced antiviral and macrophage tumoricidal activities. J Exp Med (1984) 4.86
Role of T3 surface molecules in human T-cell activation: T3-dependent activation results in an increase in cytoplasmic free calcium. Proc Natl Acad Sci U S A (1984) 4.66
Self-tolerance eliminates T cells specific for Mls-modified products of the major histocompatibility complex. Nature (1988) 4.63
Molecular mechanisms of lymphocyte-mediated cytotoxicity and their role in immunological protection and pathogenesis in vivo. Annu Rev Immunol (1996) 2.96
Down-regulation of T cell receptors on self-reactive T cells as a novel mechanism for extrathymic tolerance induction. Cell (1991) 2.83
Activators of protein kinase C down-regulate and phosphorylate the T3/T-cell antigen receptor complex of human T lymphocytes. Proc Natl Acad Sci U S A (1985) 2.10
Tolerance of T-cell clones is associated with membrane antigen changes. Nature (1983) 2.10
Kidney transplants in mice. An analysis of the immune status of mice bearing long-term, H-2 incompatible transplants. J Exp Med (1978) 1.95
Postnatal disappearance of self-reactive (V beta 6+) cells from the thymus of Mlsa mice. Implications for T cell development and autoimmunity. J Exp Med (1989) 1.78
Automated colorimetric assay for T cell cytotoxicity. J Immunol Methods (1983) 1.68
Analysis of T-cell subsets in rejection of Kb mutant skin allografts differing at class I MHC. Nature (1986) 1.41
Analysis of the time course of IFN-gamma mRNA and protein production during primary murine listeriosis. The immune phase of bacterial elimination is not temporally linked to IFN production in vivo. J Immunol (1991) 1.40
Cells mediating allograft rejection. Transplantation (1991) 1.37
Improved renal function in mouse kidney allografts lacking MHC class I antigens. J Immunol (1993) 1.24
Heightened intragraft CTL gene expression in acutely rejecting renal allografts. J Immunol (1994) 1.21
Tumor promoter phorbol esters induce unresponsiveness to antigen and expression of interleukin 2 receptor on T cells. Eur J Immunol (1985) 1.10
Activation of lymphokine genes in T cells: role of cis-acting DNA elements that respond to T cell activation signals. Pharmacol Ther (1992) 1.02
H2-M3wt-restricted, Listeria monocytogenes-specific CD8 T cells recognize a novel, hydrophobic, protease-resistant, periodate-sensitive antigen. Int Immunol (1996) 0.95
In vivo mechanisms of alloreactivity. I. Frequency of donor-reactive cytotoxic T lymphocytes in sponge matrix allografts. Transplantation (1986) 0.95
Expression of granzyme A and B proteins by cytotoxic lymphocytes involved in acute renal allograft rejection. Kidney Int (1995) 0.94
Cellular pathways for rejection of class-I-MHC--disparate skin and tumor allografts. Transplantation (1988) 0.89
Immune mechanisms in organ allograft rejection. V. Pivotal role of the cytotoxic-suppressor T cell subset in the rejection of heart grafts bearing isolated class I disparities in the inbred rat. Transplantation (1985) 0.86
The intragraft CD8+ T cell response in renal allograft rejection in the mouse. Transplantation (1996) 0.84
TcR-alpha mRNA accumulation does not dictate cell surface TcR/CD3 expression. Mol Immunol (1992) 0.81
Rejection of kidney allografts by MHC class I-deficient mice. Transplantation (1995) 0.79
Requirement of MIP-1 alpha for an inflammatory response to viral infection. Science (1995) 4.55
Toxic shock syndrome toxin-secreting Staphylococcus aureus in Kawasaki syndrome. Lancet (1993) 4.06
Evidence for the effects of a superantigen in rheumatoid arthritis. Science (1991) 3.71
Immunologic responses associated with 12 weeks of combination antiretroviral therapy consisting of zidovudine, lamivudine, and ritonavir: results of AIDS Clinical Trials Group Protocol 315. J Infect Dis (1998) 3.69
Regulation of blood pressure by the type 1A angiotensin II receptor gene. Proc Natl Acad Sci U S A (1995) 3.54
Genetic control of blood pressure and the angiotensinogen locus. Proc Natl Acad Sci U S A (1995) 3.46
Evidence for an interferon-inducible gene, Ifi202, in the susceptibility to systemic lupus. Immunity (2001) 3.18
Autoimmune disease: why and where it occurs. Nat Med (2001) 3.04
Mixed messages: modulation of inflammation and immune responses by prostaglandins and thromboxanes. J Clin Invest (2001) 2.86
Selective expansion of T cells expressing V beta 2 in toxic shock syndrome. J Exp Med (1990) 2.71
The prostaglandin receptor EP4 triggers remodelling of the cardiovascular system at birth. Nature (1997) 2.56
Selective expansion of T cells expressing T-cell receptor variable regions V beta 2 and V beta 8 in Kawasaki disease. Proc Natl Acad Sci U S A (1992) 2.56
Decreased platelet aggregation, increased bleeding time and resistance to thromboembolism in P2Y1-deficient mice. Nat Med (1999) 2.25
The contribution of L3T4+ T cells to lymphoproliferation and autoantibody production in MRL-lpr/lpr mice. J Exp Med (1988) 2.23
Reduced growth, abnormal kidney structure, and type 2 (AT2) angiotensin receptor-mediated blood pressure regulation in mice lacking both AT1A and AT1B receptors for angiotensin II. Proc Natl Acad Sci U S A (1998) 2.17
Genetic susceptibility to systemic lupus erythematosus. Annu Rev Immunol (1998) 2.14
Ultraviolet light induces binding of antibodies to selected nuclear antigens on cultured human keratinocytes. J Clin Invest (1984) 2.10
Di- and trinucleotide target preferences of somatic mutagenesis in normal and autoreactive B cells. J Immunol (1996) 2.08
Bacterial DNA induces murine interferon-gamma production by stimulation of interleukin-12 and tumor necrosis factor-alpha. Cell Immunol (1996) 2.02
Receptors for prostaglandin E(2) that regulate cellular immune responses in the mouse. J Clin Invest (2001) 1.99
Analysis of cognitive and psychological deficits in systemic lupus erythematosus patients without overt central nervous system disease. Arthritis Rheum (1996) 1.88
Angiotensin II regulates cellular immune responses through a calcineurin-dependent pathway. J Clin Invest (1999) 1.80
The binding of human immunoglobulin G1 monomer and small, covalently cross-linked polymers of immunoglobulin G1 to human peripheral blood monocytes and polymorphonuclear leukocytes. J Clin Invest (1982) 1.78
Nephropathy in human immunodeficiency virus-1 transgenic mice is due to renal transgene expression. J Clin Invest (1997) 1.77
Treatment of intractable rheumatoid arthritis with total lymphoid irradiation. N Engl J Med (1981) 1.69
Reproductive failure and reduced blood pressure in mice lacking the EP2 prostaglandin E2 receptor. J Clin Invest (1999) 1.66
Selective stimulation of human T cells with streptococcal erythrogenic toxins A and B. J Immunol (1991) 1.65
The contribution of NZW genes to lupus-like disease in (NZB x NZW)F1 mice. J Exp Med (1987) 1.64
Analysis of clonal CD8+ T cell expansions in normal individuals and patients with rheumatoid arthritis. J Immunol (1995) 1.64
Angiotensin II responses in AT1A receptor-deficient mice: a role for AT1B receptors in blood pressure regulation. Am J Physiol (1997) 1.64
The prostaglandin E2 EP1 receptor mediates pain perception and regulates blood pressure. J Clin Invest (2001) 1.60
Divergent functions of angiotensin II receptor isoforms in the brain. J Clin Invest (2000) 1.59
Altered inflammatory responses in leukotriene-deficient mice. Proc Natl Acad Sci U S A (1994) 1.59
Beryllium presentation to CD4+ T cells underlies disease-susceptibility HLA-DP alleles in chronic beryllium disease. Proc Natl Acad Sci U S A (2000) 1.57
In vivo transfer of GPI-linked complement restriction factors from erythrocytes to the endothelium. Science (1995) 1.56
Monoclonal anti-histone autoantibodies derived from murine models of lupus. J Immunol (1984) 1.52
Characterization of T cell repertoire changes in acute Kawasaki disease. J Exp Med (1993) 1.51
Association of psychiatric manifestations with antibodies to ribosomal P proteins in systemic lupus erythematosus. Am J Med (1991) 1.51
A role for fractalkine and its receptor (CX3CR1) in cardiac allograft rejection. J Immunol (2000) 1.49
Simultaneous presentation of Kawasaki disease and toxic shock syndrome in an adolescent male. Pediatr Infect Dis J (1996) 1.48
The blockade of Fc receptor-mediated clearance of immune complexes in vivo by a monoclonal antibody (2.4G2) directed against Fc receptors on murine leukocytes. J Immunol (1984) 1.48
Coagulation defects and altered hemodynamic responses in mice lacking receptors for thromboxane A2. J Clin Invest (1998) 1.46
Crosstransplantation of kidneys in normal and Hyp mice. Evidence that the Hyp mouse phenotype is unrelated to an intrinsic renal defect. J Clin Invest (1992) 1.45
Analysis of the New Zealand Black contribution to lupus-like renal disease. Multiple genes that operate in a threshold manner. J Immunol (1995) 1.44
Genetic basis of systemic lupus erythematosus. Curr Opin Immunol (1996) 1.43
Analysis of the time course of IFN-gamma mRNA and protein production during primary murine listeriosis. The immune phase of bacterial elimination is not temporally linked to IFN production in vivo. J Immunol (1991) 1.40
Type I interferon signaling is involved in the spontaneous development of lupus-like disease in B6.Nba2 and (B6.Nba2 x NZW)F(1) mice. Genes Immun (2007) 1.39
Superantigens: biology, immunology, and potential role in disease. J Clin Immunol (1992) 1.38
Genetic analysis of the NZB contribution to lupus-like autoimmune disease in (NZB x NZW)F1 mice. Proc Natl Acad Sci U S A (1994) 1.35
Identification of specific EP receptors responsible for the hemodynamic effects of PGE2. Am J Physiol (1999) 1.33
Neuropsychiatric lupus erythematosus: a 10-year prospective study on the value of diagnostic tests. Am J Med (1995) 1.31
The role of environmental antigens in the spontaneous development of autoimmunity in MRL-lpr mice. J Immunol (1999) 1.30
Identification of pathogenic T cells in patients with beryllium-induced lung disease. J Immunol (1999) 1.29
Activation of the murine EP3 receptor for PGE2 inhibits cAMP production and promotes platelet aggregation. J Clin Invest (2001) 1.29
Clonal expansions of activated gamma/delta T cells in recent-onset multiple sclerosis. Proc Natl Acad Sci U S A (1993) 1.29
A large deletion within the T-cell receptor beta-chain gene complex in New Zealand white mice. Science (1985) 1.27
Regulation of sodium balance and blood pressure by the AT(1A) receptor for angiotensin II. Hypertension (2000) 1.26
Renal growth and development in mice lacking AT1A receptors for angiotensin II. Am J Physiol (1998) 1.25
Autoimmunization in murine graft-vs-host disease. I. Selective production of antibodies to histones and DNA. J Immunol (1985) 1.24
Selection of the T cell receptor repertoire in Lpr mice. J Immunol (1993) 1.24
Weekly pulse methotrexate in rheumatoid arthritis. Clinical and immunologic effects in a randomized, double-blind study. Ann Intern Med (1985) 1.23
Cardiovascular responses to the isoprostanes iPF(2alpha)-III and iPE(2)-III are mediated via the thromboxane A(2) receptor in vivo. Circulation (2000) 1.21
Anti-histone antibodies in idiopathic and drug-induced lupus recognize distinct intrahistone regions. J Immunol (1987) 1.20
Reversible and irreversible loss of Fc receptor function of human monocytes as a consequence of interaction with immunoglobulin G. J Clin Invest (1980) 1.20
Expansions of T-cell subsets expressing particular T-cell receptor variable regions in chronic beryllium disease. Am J Respir Cell Mol Biol (1998) 1.20
Quantitative influence of antibody and complement coating of red cells on monocyte-mediated cell lysis. J Clin Invest (1978) 1.18
Induction of immunoglobulin secreting cells in the human autologous mixed leukocyte reaction: regulation by helper and suppressor lymphocyte subsets defined with monoclonal antibodies. J Immunol (1981) 1.17
Failure of spermatogenesis in mouse lines deficient in the Na(+)-K(+)-2Cl(-) cotransporter. J Clin Invest (2000) 1.17
Urinary concentrating function in mice lacking EP3 receptors for prostaglandin E2. Am J Physiol (1998) 1.16
Greatly reduced lymphoproliferation in lpr mice lacking major histocompatibility complex class I. J Exp Med (1995) 1.16
Human peripheral blood monocytes display surface antigens recognized by monoclonal antinuclear antibodies. J Clin Invest (1985) 1.15
Abnormal water metabolism in mice lacking the type 1A receptor for ANG II. Am J Physiol Renal Physiol (2000) 1.15
Cytokine expression in vivo during murine listeriosis. Infection with live, virulent bacteria is required for monokine and lymphokine messenger RNA accumulation in the spleen. J Immunol (1992) 1.15
Inhibition of T cells proliferation and SLE-like syndrome of MRL/1 mice by whole body or total lymphoid irradiation. J Immunol (1980) 1.14
Immune reconstitution in the first year of potent antiretroviral therapy and its relationship to virologic response. J Infect Dis (2000) 1.13
Identification of class II major histocompatibility complex and T cell receptor binding sites in the superantigen toxic shock syndrome toxin 1. J Exp Med (1995) 1.13
MHC-unrestricted transfer of antilisterial immunity by freshly isolated immune CD8 spleen cells. J Immunol (1989) 1.12
Reversal of nzb/nzw disease with total lymphoid irradiation. J Exp Med (1979) 1.12
Possible role of insertion sequence IS257 in dissemination and expression of high- and low-level trimethoprim resistance in staphylococci. Antimicrob Agents Chemother (1994) 1.11
Effect of genetic background on the contribution of New Zealand black loci to autoimmune lupus nephritis. Proc Natl Acad Sci U S A (1996) 1.11
Heterogeneity of autoreactive T cell clones specific for the E2 component of the pyruvate dehydrogenase complex in primary biliary cirrhosis. J Exp Med (1995) 1.11
Transport of phosphorothioate oligonucleotides in kidney: implications for molecular therapy. Kidney Int (1995) 1.11
Control of multiple autoantibodies linked with a lupus nephritis susceptibility locus in New Zealand black mice. J Immunol (1997) 1.09
Clonal expansion of lung V delta 1+ T cells in pulmonary sarcoidosis. J Clin Invest (1993) 1.09
Characterization of the IgG-Fc receptor on human platelets. Blood (1982) 1.09
Characterization of the pattern of inflammatory cell influx and cytokine production during the murine host response to Listeria monocytogenes. J Immunol (1988) 1.09
bcl-2 transgenic Lpr mice show profound enhancement of lymphadenopathy. J Immunol (1995) 1.08
TCR expression of activated T cell clones in the lungs of patients with pulmonary sarcoidosis. J Immunol (1994) 1.07
Chronic beryllium disease: T cell recognition of a metal presented by HLA-DP. Clin Immunol (2001) 1.07
Renal function in the AT1A receptor knockout mouse during normal and volume-expanded conditions. Kidney Int (1999) 1.06
Diabetes insipidus in uricase-deficient mice: a model for evaluating therapy with poly(ethylene glycol)-modified uricase. J Am Soc Nephrol (2001) 1.04
The role of L3T4+ cells in the pathogenesis of lupus in lpr-bearing mice. I. Defects in the production of interleukins 2 and 3. Eur J Immunol (1987) 1.04
Selective accumulation of related CD4+ T cell clones in the synovial fluid of patients with rheumatoid arthritis. J Immunol (1998) 1.04
Genetic contributions to lupus-like disease in (NZB x NZW)F1 mice. Immunol Rev (1995) 1.02
Chronic rejection of mouse kidney allografts. Kidney Int (1999) 1.02
Induction of immunoglobulin-secreting cells in the allogeneic mixed leukocyte reaction: regulation by helper and suppressor lymphocyte subsets in man. J Immunol (1981) 1.02