Published in J Biol Chem on July 03, 1998
Hepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis. Mol Cell Biol (2001) 8.95
Peroxisome proliferator-activated receptor alpha mediates the adaptive response to fasting. J Clin Invest (1999) 6.99
PPAR gamma and human metabolic disease. J Clin Invest (2006) 3.83
Sorting out the roles of PPAR alpha in energy metabolism and vascular homeostasis. J Clin Invest (2006) 3.48
Growth, adipose, brain, and skin alterations resulting from targeted disruption of the mouse peroxisome proliferator-activated receptor beta(delta). Mol Cell Biol (2000) 3.37
Cyclo-oxygenase-2-derived prostacyclin mediates embryo implantation in the mouse via PPARdelta. Genes Dev (1999) 2.37
Peroxisome proliferator-activated receptor alpha target genes. PPAR Res (2010) 2.09
Inhibition of RXR and PPARgamma ameliorates diet-induced obesity and type 2 diabetes. J Clin Invest (2001) 1.97
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A current review of fatty acid transport proteins (SLC27). Pflugers Arch (2003) 1.65
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PPARgamma regulates adipose triglyceride lipase in adipocytes in vitro and in vivo. Am J Physiol Endocrinol Metab (2007) 1.61
Transmembrane movement of exogenous long-chain fatty acids: proteins, enzymes, and vectorial esterification. Microbiol Mol Biol Rev (2003) 1.55
Muscle-derived angiopoietin-like protein 4 is induced by fatty acids via peroxisome proliferator-activated receptor (PPAR)-delta and is of metabolic relevance in humans. Diabetes (2008) 1.48
Profiling of promoter occupancy by PPARalpha in human hepatoma cells via ChIP-chip analysis. Nucleic Acids Res (2010) 1.34
Peroxisome proliferator-activated receptor targets for the treatment of metabolic diseases. Mediators Inflamm (2013) 1.27
Fatty acid synthase and liver triglyceride metabolism: housekeeper or messenger? Biochim Biophys Acta (2011) 1.27
The expression of GPIHBP1, an endothelial cell binding site for lipoprotein lipase and chylomicrons, is induced by peroxisome proliferator-activated receptor-gamma. Mol Endocrinol (2008) 1.23
Role of peroxisome proliferators-activated receptors in the pathogenesis and treatment of nonalcoholic fatty liver disease. World J Gastroenterol (2008) 1.22
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Heightened expression of cyclooxygenase-2 and peroxisome proliferator-activated receptor-delta in human endometrial adenocarcinoma. Neoplasia (2001) 1.18
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Genetic activation of Nrf2 protects against fasting-induced oxidative stress in livers of mice. PLoS One (2013) 0.95
Peroxisome proliferator-activated receptor (PPAR)gamma can inhibit chronic renal allograft damage. Am J Pathol (2010) 0.95
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Maternal di-(2-ethylhexyl)-phthalate exposure influences essential fatty acid homeostasis in rat placenta. Placenta (2008) 0.94
Bezafibrate at clinically relevant doses decreases serum/liver triglycerides via down-regulation of sterol regulatory element-binding protein-1c in mice: a novel peroxisome proliferator-activated receptor alpha-independent mechanism. Mol Pharmacol (2009) 0.93
Protein profiling of mouse livers with peroxisome proliferator-activated receptor alpha activation. Mol Cell Biol (2004) 0.92
Peroxisome proliferator-activated receptor {alpha} is responsible for the up-regulation of hepatic glucose-6-phosphatase gene expression in fasting and db/db Mice. J Biol Chem (2010) 0.92
Keap1-knockdown decreases fasting-induced fatty liver via altered lipid metabolism and decreased fatty acid mobilization from adipose tissue. PLoS One (2013) 0.91
Hormonal and nutritional regulation of alternative CD36 transcripts in rat liver--a role for growth hormone in alternative exon usage. BMC Mol Biol (2007) 0.91
Differential effects of contraction and PPAR agonists on the expression of fatty acid transporters in rat skeletal muscle. J Physiol (2006) 0.88
Fish oil and fenofibrate prevented phosphorylation-dependent hepatic sortilin 1 degradation in Western diet-fed mice. J Biol Chem (2014) 0.88
Fatty Acid modulation of the endocannabinoid system and the effect on food intake and metabolism. Int J Endocrinol (2013) 0.86
15-deoxy-Delta12,14-prostaglandin J2 (15d-PGJ2) and ciglitazone modulate Staphylococcus aureus-dependent astrocyte activation primarily through a PPAR-gamma-independent pathway. J Neurochem (2006) 0.86
Phospholipid--driven gene regulation. FEBS Lett (2013) 0.83
Anticancer Role of PPARgamma Agonists in Hematological Malignancies Found in the Vasculature, Marrow, and Eyes. PPAR Res (2010) 0.83
Metabolic reserve of the heart: the forgotten link between contraction and coronary flow. Prog Cardiovasc Dis (2008) 0.83
Fatty acid signaling: the new function of intracellular lipases. Int J Mol Sci (2015) 0.83
Crocetin improves the insulin resistance induced by high-fat diet in rats. Br J Pharmacol (2008) 0.82
Transcriptional regulation of lipid metabolism by fatty acids: a key determinant of pancreatic beta-cell function. Nutr Metab (Lond) (2005) 0.82
Obesity Determines the Immunophenotypic Profile and Functional Characteristics of Human Mesenchymal Stem Cells From Adipose Tissue. Stem Cells Transl Med (2016) 0.81
Hepatic fat accumulation and regulation of FAT/CD36: an effect of hepatic irradiation. Int J Clin Exp Pathol (2014) 0.81
PPAR and liver injury in HIV-infected patients. PPAR Res (2009) 0.80
Correction of dysfunctional fatty acid metabolism using peroxisome proliferator activated receptor gamma agonists. J R Soc Med (2002) 0.79
Role of Esrrg in the fibrate-mediated regulation of lipid metabolism genes in human ApoA-I transgenic mice. Pharmacogenomics J (2009) 0.79
Comparative Studies of Vertebrate Platelet Glycoprotein 4 (CD36). Biomolecules (2012) 0.79
The interaction between HCV and nuclear receptor-mediated pathways. Pharmacol Ther (2011) 0.78
Possible role of intestinal fatty acid oxidation in the eating-inhibitory effect of the PPAR-α agonist Wy-14643 in high-fat diet fed rats. PLoS One (2013) 0.78
The pathological roles of environmental and redox stresses in cardiovascular diseases. Environ Health Prev Med (2012) 0.78
Modulation of the transcriptional activity of peroxisome proliferator-activated receptor gamma by protein-protein interactions and post-translational modifications. Yonsei Med J (2013) 0.77
Determination of PPARγ activity in adipose tissue and spleen. J Immunoassay Immunochem (2012) 0.77
PPARα via HNF4α regulates the expression of genes encoding hepatic amino acid catabolizing enzymes to maintain metabolic homeostasis. Genes Nutr (2015) 0.76
Peroxisome proliferator-activated receptor α mediates enhancement of gene expression of cerebroside sulfotransferase in several murine organs. Glycoconj J (2012) 0.76
Combined effect of sesamin and soybean phospholipid on hepatic fatty acid metabolism in rats. J Clin Biochem Nutr (2014) 0.75
PPARs and nonalcoholic fatty liver disease. Biochimie (2016) 0.75
Role of BAF60a/BAF60c in chromatin remodeling and hepatic lipid metabolism. Nutr Metab (Lond) (2016) 0.75
Diabetic Cardiomyopathy: An Immunometabolic Perspective. Front Endocrinol (Lausanne) (2017) 0.75
OSBPL10, RXRA and lipid metabolism confer African-ancestry protection against dengue haemorrhagic fever in admixed Cubans. PLoS Pathog (2017) 0.75
Bilobetin ameliorates insulin resistance by PKA-mediated phosphorylation of PPARα in rats fed a high-fat diet. Br J Pharmacol (2012) 0.75
Fenofibrate unexpectedly induces cardiac hypertrophy in mice lacking MuRF1. Cardiovasc Pathol (2015) 0.75
Chromium Propionate Enhances Adipogenic Differentiation of Bovine Intramuscular Adipocytes. Front Vet Sci (2015) 0.75
Administration of mesenchymal stromal cells before renal ischemia/reperfusion attenuates kidney injury and may modulate renal lipid metabolism in rats. Sci Rep (2017) 0.75
Lower Expression of SLC27A1 Enhances Intramuscular Fat Deposition in Chicken via Down-Regulated Fatty Acid Oxidation Mediated by CPT1A. Front Physiol (2017) 0.75
Pharmacological Activation of Peroxisome Proliferator-Activated Receptor {Delta} Increases Sphingomyelin Synthase Activity in THP-1 Macrophage-Derived Foam Cell. Inflammation (2016) 0.75
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