Published in Dev Biol on June 15, 1998
The mouse snail gene encodes a key regulator of the epithelial-mesenchymal transition. Mol Cell Biol (2001) 4.80
Aberrant expression of the transcription factors snail and slug alters the response to genotoxic stress. Mol Cell Biol (2004) 2.80
The Notch ligand JAG1 is required for sensory progenitor development in the mammalian inner ear. PLoS Genet (2006) 2.56
Signaling mechanisms of the epithelial-mesenchymal transition. Sci Signal (2014) 2.42
Slug is a direct Notch target required for initiation of cardiac cushion cellularization. J Cell Biol (2008) 2.21
Fine tuning of craniofacial morphology by distant-acting enhancers. Science (2013) 2.16
Direct repression of cyclin D1 by SIP1 attenuates cell cycle progression in cells undergoing an epithelial mesenchymal transition. Mol Biol Cell (2007) 1.71
Human Slug is a repressor that localizes to sites of active transcription. Mol Cell Biol (2000) 1.63
Snail2 directly represses cadherin6B during epithelial-to-mesenchymal transitions of the neural crest. Development (2007) 1.58
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Identification of novel candidate gene loci and increased sex chromosome aneuploidy among infants with conotruncal heart defects. Am J Med Genet A (2013) 1.48
Expression of Wnt9b and activation of canonical Wnt signaling during midfacial morphogenesis in mice. Dev Dyn (2006) 1.44
Roles of the transcription factors snail and slug during mammary morphogenesis and breast carcinoma progression. J Mammary Gland Biol Neoplasia (2004) 1.33
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Cardiovascular development and the colonizing cardiac neural crest lineage. ScientificWorldJournal (2007) 1.26
Notch signaling is required for the generation of hair cells and supporting cells in the mammalian inner ear. Proc Natl Acad Sci U S A (2010) 1.25
Erk5 controls Slug expression and keratinocyte activation during wound healing. Mol Biol Cell (2008) 1.20
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Modularity and reshuffling of Snail and Slug expression during vertebrate evolution. Proc Natl Acad Sci U S A (2002) 1.15
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Negative regulation of the expressions of cytokeratins 8 and 19 by SLUG repressor protein in human breast cells. Biochem Biophys Res Commun (2005) 1.07
Bmpr1a signaling plays critical roles in palatal shelf growth and palatal bone formation. Dev Biol (2010) 1.06
Differential role of Snail1 and Snail2 zinc fingers in E-cadherin repression and epithelial to mesenchymal transition. J Biol Chem (2013) 1.06
Identification of a ZEB2-MITF-ZEB1 transcriptional network that controls melanogenesis and melanoma progression. Cell Death Differ (2014) 1.05
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Premature differentiation and aberrant movement of pituitary cells lacking both Hes1 and Prop1. Dev Biol (2008) 1.01
Cutaneous wound reepithelialization is compromised in mice lacking functional Slug (Snai2). J Dermatol Sci (2009) 1.00
Mmp15 is a direct target of Snai1 during endothelial to mesenchymal transformation and endocardial cushion development. Dev Biol (2011) 0.99
Slug controls stem/progenitor cell growth dynamics during mammary gland morphogenesis. PLoS One (2012) 0.98
Slug expression during melanoma progression. Am J Pathol (2012) 0.97
The cleft lip and palate defects in Dancer mutant mice result from gain of function of the Tbx10 gene. Proc Natl Acad Sci U S A (2004) 0.97
Cell-state transitions regulated by SLUG are critical for tissue regeneration and tumor initiation. Stem Cell Reports (2014) 0.97
Regional development of uterine decidualization: molecular signaling by Hoxa-10. Mol Reprod Dev (2010) 0.96
Compensatory regulation of the Snai1 and Snai2 genes during chondrogenesis. J Bone Miner Res (2013) 0.95
Unexpected functional redundancy between Twist and Slug (Snail2) and their feedback regulation of NF-kappaB via Nodal and Cerberus. Dev Biol (2009) 0.95
SLUG: Critical regulator of epithelial cell identity in breast development and cancer. Cell Adh Migr (2014) 0.94
Soluble HB-EGF induces epithelial-to-mesenchymal transition in inner medullary collecting duct cells by upregulating Snail-2. Am J Physiol Renal Physiol (2009) 0.94
Deletion of Snai2 and Snai3 results in impaired physical development compounded by lymphocyte deficiency. PLoS One (2013) 0.92
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Peroxisome proliferator-activated receptor-gamma inhibits transformed growth of non-small cell lung cancer cells through selective suppression of Snail. Neoplasia (2010) 0.92
Snai1 regulates cell lineage allocation and stem cell maintenance in the mouse intestinal epithelium. EMBO J (2015) 0.92
Identification and developmental expression analysis of a novel homeobox gene closely linked to the mouse Twirler mutation. Gene Expr Patterns (2006) 0.91
Snail family members unequally trigger EMT and thereby differ in their ability to promote the neoplastic transformation of mammary epithelial cells. PLoS One (2014) 0.89
Mutations in snail family genes enhance craniosynostosis of Twist1 haplo-insufficient mice: implications for Saethre-Chotzen Syndrome. Genetics (2005) 0.88
Angiogenic sprouting is regulated by endothelial cell expression of Slug. J Cell Sci (2014) 0.88
Regulation of the protein stability of EMT transcription factors. Cell Adh Migr (2014) 0.88
Snail2 controls mesodermal BMP/Wnt induction of neural crest. Development (2011) 0.87
Slug deficiency enhances self-renewal of hematopoietic stem cells during hematopoietic regeneration. Blood (2009) 0.87
Characterization of the SNAG and SLUG domains of Snail2 in the repression of E-cadherin and EMT induction: modulation by serine 4 phosphorylation. PLoS One (2012) 0.87
Snai2 expression enhances ultraviolet radiation-induced skin carcinogenesis. Am J Pathol (2007) 0.86
Transcriptomal profiling of the cellular response to DNA damage mediated by Slug (Snai2). Br J Cancer (2008) 0.86
The zinc finger transcription factors Osr1 and Osr2 control synovial joint formation. Dev Biol (2011) 0.86
Overexpression of Snai3 suppresses lymphoid- and enhances myeloid-cell differentiation. Eur J Immunol (2012) 0.85
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SNAI1 and SNAI2 are asymmetrically expressed at the 2-cell stage and become segregated to the TE in the mouse blastocyst. PLoS One (2009) 0.83
DNA methylation is associated with transcription of Snail and Slug genes. Biochem Biophys Res Commun (2012) 0.82
KIT is required for hepatic function during mouse post-natal development. BMC Dev Biol (2007) 0.79
Inhibitory effects of cigarette smoke extract on neural crest migration occur through suppression of R-spondin1 expression via aryl hydrocarbon receptor. Naunyn Schmiedebergs Arch Pharmacol (2009) 0.78
A new role of SNAI2 in postlactational involution of the mammary gland links it to luminal breast cancer development. Oncogene (2015) 0.77
Inhibition of Snail Family Transcriptional Repressor 2 (SNAI2) Enhances Multidrug Resistance of Hepatocellular Carcinoma Cells. PLoS One (2016) 0.75
Role of the Slug Transcription Factor in Chemically-Induced Skin Cancer. J Clin Med (2016) 0.75
Slug inhibits pancreatic cancer initiation by blocking Kras-induced acinar-ductal metaplasia. Sci Rep (2016) 0.75
Loss of Snail2 favors skin tumor progression by promoting the recruitment of myeloid progenitors. Carcinogenesis (2015) 0.75
Absence of a major role for the snai1 and snai3 genes in regulating skeletal muscle regeneration in mice. PLoS Curr (2013) 0.75
Potential Involvement of Snail Members in Neuronal Survival and Astrocytic Migration during the Gecko Spinal Cord Regeneration. Front Cell Neurosci (2017) 0.75
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Notch signalling pathway mediates hair cell development in mammalian cochlea. Nat Genet (1999) 3.37
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Differential susceptibility of inbred mouse strains to dextran sulfate sodium-induced colitis. Am J Physiol (1998) 2.76
Defects in limb, craniofacial, and thymic development in Jagged2 mutant mice. Genes Dev (1998) 2.70
Notch activity influences the alphabeta versus gammadelta T cell lineage decision. Cell (1997) 2.66
Defects in somite formation in lunatic fringe-deficient mice. Nature (1998) 2.37
Defects in development of the kidney, heart and eye vasculature in mice homozygous for a hypomorphic Notch2 mutation. Development (2001) 2.37
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Spontaneous mutations in the mouse Sharpin gene result in multiorgan inflammation, immune system dysregulation and dermatitis. Genes Immun (2007) 2.05
Expression pattern of Motch, a mouse homolog of Drosophila Notch, suggests an important role in early postimplantation mouse development. Development (1992) 1.99
An invasive spirochaete associated with interdigital papillomatosis of dairy cattle. Vet Rec (1992) 1.90
Lesions of aryl-hydrocarbon receptor-deficient mice. Vet Pathol (1997) 1.85
Scd1 is expressed in sebaceous glands and is disrupted in the asebia mouse. Nat Genet (1999) 1.84
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Loss of normal profilaggrin and filaggrin in flaky tail (ft/ft) mice: an animal model for the filaggrin-deficient skin disease ichthyosis vulgaris. J Invest Dermatol (2000) 1.69
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The Nrarp gene encodes an ankyrin-repeat protein that is transcriptionally regulated by the notch signaling pathway. Dev Biol (2001) 1.54
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Experimental induction of alopecia areata-like hair loss in C3H/HeJ mice using full-thickness skin grafts. J Invest Dermatol (1998) 1.46
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