Published in Circulation on August 25, 1998
A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance. Cell Metab (2009) 11.46
Low grade inflammation and coronary heart disease: prospective study and updated meta-analyses. BMJ (2000) 6.10
Markers of inflammation, coagulation, and renal function are elevated in adults with HIV infection. J Infect Dis (2010) 5.35
Guidelines for the primary prevention of stroke: a statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke (2014) 3.48
Women and ischemic heart disease: evolving knowledge. J Am Coll Cardiol (2009) 2.49
Disease-modifying antirheumatic drugs are associated with a reduced risk for cardiovascular disease in patients with rheumatoid arthritis: a case control study. Arthritis Res Ther (2006) 2.28
Traditional risk factors and D-dimer predict incident cardiovascular disease events in chronic HIV infection. AIDS (2010) 2.22
Elevated C-reactive protein levels are associated with postoperative events in patients undergoing lower extremity vein bypass surgery. J Vasc Surg (2006) 2.14
Association between dietary fiber and serum C-reactive protein. Am J Clin Nutr (2006) 2.07
Generation of C-reactive protein and complement components in atherosclerotic plaques. Am J Pathol (2001) 2.01
Tumor necrosis factor receptor levels are associated with carotid atherosclerosis. Stroke (2002) 1.94
Two loci on chromosomes 2 and X for premature coronary heart disease identified in early- and late-settlement populations of Finland. Am J Hum Genet (2000) 1.93
Association between the gene encoding 5-lipoxygenase-activating protein and stroke replicated in a Scottish population. Am J Hum Genet (2005) 1.91
Autoantibodies and the risk of cardiovascular events. J Rheumatol (2009) 1.89
Socioeconomic and racial/ethnic differentials of C-reactive protein levels: a systematic review of population-based studies. BMC Public Health (2007) 1.88
Aggregate risk score based on markers of inflammation, cell stress, and coagulation is an independent predictor of adverse cardiovascular outcomes. J Am Coll Cardiol (2013) 1.77
Assessing salivary C-reactive protein: longitudinal associations with systemic inflammation and cardiovascular disease risk in women exposed to intimate partner violence. Brain Behav Immun (2012) 1.77
Association between dietary fiber and markers of systemic inflammation in the Women's Health Initiative Observational Study. Nutrition (2008) 1.69
Persistence with statins and onset of rheumatoid arthritis: a population-based cohort study. PLoS Med (2010) 1.66
Independent and additive effects of cytokine patterns and the metabolic syndrome on arterial aging in the SardiNIA Study. Atherosclerosis (2010) 1.65
Lipids and inflammation: serial measurements of the lipid profile of blood donors who later developed rheumatoid arthritis. Ann Rheum Dis (2006) 1.56
Endothelial dysfunction in young patients with rheumatoid arthritis and low disease activity. Ann Rheum Dis (2004) 1.53
Early origins of inflammation: microbial exposures in infancy predict lower levels of C-reactive protein in adulthood. Proc Biol Sci (2009) 1.51
Association of bronchial hyperresponsiveness and lung function with C-reactive protein (CRP): a population based study. Thorax (2004) 1.49
Severe extra-articular disease manifestations are associated with an increased risk of first ever cardiovascular events in patients with rheumatoid arthritis. Ann Rheum Dis (2006) 1.42
C-reactive protein and ischemia in users and nonusers of beta-blockers and statins: data from the Heart and Soul Study. Circulation (2003) 1.40
Obesity and C-reactive protein levels among white, black, and hispanic US adults. Obesity (Silver Spring) (2008) 1.38
Cardiovascular risk in rheumatoid arthritis: recent advances in the understanding of the pivotal role of inflammation, risk predictors and the impact of treatment. Rheumatology (Oxford) (2014) 1.34
Inflammation in chronic kidney disease: role in the progression of renal and cardiovascular disease. Pediatr Nephrol (2008) 1.29
Systemic inflammation in cardiovascular and periodontal disease: comparative study. Clin Diagn Lab Immunol (2002) 1.19
C-reactive protein and rate of dementia in carriers and non carriers of Apolipoprotein APOE4 genotype. Neurobiol Aging (2007) 1.19
Admission C-reactive protein after acute ischemic stroke is associated with stroke severity and mortality: the 'Bergen stroke study'. BMC Neurol (2009) 1.17
Arterial cardiovascular risk factors and venous thrombosis: results from a population-based, prospective study (the HUNT 2). Haematologica (2009) 1.15
Decreased C-reactive protein levels in Alzheimer disease. J Geriatr Psychiatry Neurol (2009) 1.15
Parental education is related to C-reactive protein among female middle-aged community volunteers. Brain Behav Immun (2009) 1.14
Population differences in proinflammatory biology: Japanese have healthier profiles than Americans. Brain Behav Immun (2010) 1.14
Interleukin-6 and rheumatic diseases. Arthritis Res Ther (2006) 1.14
Sleep duration, cardiovascular disease, and proinflammatory biomarkers. Nat Sci Sleep (2013) 1.13
Inflammatory and thrombotic mechanisms in coronary atherosclerosis. Heart (2003) 1.13
Obesity and inflammation: epidemiology, risk factors, and markers of inflammation. Int J Endocrinol (2013) 1.12
Relation of low socioeconomic status to C-reactive protein in patients with coronary heart disease (from the heart and soul study). Am J Cardiol (2005) 1.11
Frailty and its potential relevance to cardiovascular care. Mayo Clin Proc (2008) 1.08
Cardiovascular risk assessment--from individual risk prediction to estimation of global risk and change in risk in the population. BMC Med (2010) 1.08
Inflammatory mechanisms of stroke. Stroke (2010) 1.06
DHA supplementation decreases serum C-reactive protein and other markers of inflammation in hypertriglyceridemic men. J Nutr (2009) 1.06
C-reactive protein, interleukin 6 and lung cancer risk: a meta-analysis. PLoS One (2012) 1.05
High-sensitivity C-reactive protein predicts mortality but not stroke: the Northern Manhattan Study. Neurology (2009) 1.05
C-reactive protein and other markers of inflammation in hemodialysis patients. Caspian J Intern Med (2013) 1.05
Vascular inflammation and endothelial dysfunction in experimental hypertension. Int J Hypertens (2011) 1.03
High-sensitivity C-reactive protein and gamma-glutamyl transferase levels are synergistically associated with metabolic syndrome in community-dwelling persons. Cardiovasc Diabetol (2010) 1.02
Incidence of noncardiac vascular disease in rheumatoid arthritis and relationship to extraarticular disease manifestations. Arthritis Rheum (2006) 1.02
Racial differences in C-reactive protein levels during normal pregnancy. Am J Obstet Gynecol (2008) 1.01
Lifecourse socioeconomic trajectories and C-reactive protein levels in young adults: findings from a Brazilian birth cohort. Soc Sci Med (2010) 1.01
Sex/gender medicine. The biological basis for personalized care in cardiovascular medicine. Circ J (2009) 1.01
Relation of genetic variation in the gene coding for C-reactive protein with its plasma protein concentrations: findings from the Women's Health Initiative Observational Cohort. Clin Chem (2008) 1.00
Statin treatment for rheumatoid arthritis: a promising novel indication. Clin Rheumatol (2007) 1.00
Early effects of gastric bypass on endothelial function, inflammation, and cardiovascular risk in obese patients. Surg Endosc (2011) 1.00
Objectively measured physical activity and C-reactive protein: National Health and Nutrition Examination Survey 2003-2004. Scand J Med Sci Sports (2011) 0.99
Do environments in infancy moderate the association between stress and inflammation in adulthood? Initial evidence from a birth cohort in the Philippines. Brain Behav Immun (2012) 0.99
Plasma biomarkers for prediction of sudden cardiac death: another piece of the risk stratification puzzle? Circ Arrhythm Electrophysiol (2012) 0.98
Atorvastatin induces associated reductions in platelet P-selectin, oxidized low-density lipoprotein, and interleukin-6 in patients with coronary artery diseases. Heart Vessels (2008) 0.98
Intake of trans fat and all-cause mortality in the Reasons for Geographical and Racial Differences in Stroke (REGARDS) cohort. Am J Clin Nutr (2013) 0.96
Lack of significant association between type 2 diabetes mellitus with longitudinal change in diurnal salivary cortisol: the multiethnic study of atherosclerosis. Endocrine (2016) 0.96
Low-carbohydrate and high-fat intake among adult patients with poorly controlled type 2 diabetes mellitus. Nutrition (2006) 0.95
High levels of inflammatory biomarkers are associated with increased allele-specific apolipoprotein(a) levels in African-Americans. J Clin Endocrinol Metab (2008) 0.94
C-reactive protein and nitric oxide levels in ischemic stroke and its subtypes: correlation with clinical outcome. Inflammation (2012) 0.94
Inflammation in acute coronary syndromes. Heart (2002) 0.94
Racial/ethnic and gender differences in the association between self-reported experiences of racial/ethnic discrimination and inflammation in the CARDIA cohort of 4 US communities. Soc Sci Med (2012) 0.93
Dyslipidaemia as a predictor of hypertension in middle-aged men. Eur Heart J (2008) 0.93
Interpersonal violence, PTSD, and inflammation: potential psychogenic pathways to higher C-reactive protein levels. Cytokine (2013) 0.93
Assessing inflammatory status in cardiovascular disease. Heart (2007) 0.92
Impact of sex hormone metabolism on the vascular effects of menopausal hormone therapy in cardiovascular disease. Curr Drug Metab (2010) 0.92
The effect of aerobic versus strength-based training on high-sensitivity C-reactive protein in older adults. Eur J Appl Physiol (2010) 0.92
Effect of marine-derived n-3 polyunsaturated fatty acids on C-reactive protein, interleukin 6 and tumor necrosis factor α: a meta-analysis. PLoS One (2014) 0.92
Chronic Inflammation and Coronary Atherosclerosis in Patients with End-Stage Renal Disease. Cardiorenal Med (2012) 0.91
C-reactive protein and coronary artery calcium in asymptomatic women with systemic lupus erythematosus or rheumatoid arthritis. Am J Cardiol (2008) 0.91
The Levels of Inflammatory Markers in the Treatment of Stroke study (LIMITS): inflammatory biomarkers as risk predictors after lacunar stroke. Int J Stroke (2010) 0.90
Predictors of cardiovascular damage in patients with systemic lupus erythematosus: data from LUMINA (LXVIII), a multiethnic US cohort. Rheumatology (Oxford) (2009) 0.89
Association of circulating C-reactive protein and interleukin-6 with longevity into the 80s and 90s: The Rancho Bernardo Study. J Clin Endocrinol Metab (2010) 0.89
Ongoing clinical trials of the pleiotropic effects of statins. Vasc Health Risk Manag (2005) 0.89
Management of cardiovascular risk in patients with rheumatoid arthritis: evidence and expert opinion. Ther Adv Musculoskelet Dis (2013) 0.89
Sex-differentiated changes in C-reactive protein from ages 9 to 21: the contributions of BMI and physical/sexual maturation. Psychoneuroendocrinology (2013) 0.89
Whole grains are associated with serum concentrations of high sensitivity C-reactive protein among premenopausal women. J Nutr (2010) 0.89
Increased myocardial prevalence of C-reactive protein in human coronary heart disease: direct effects on microvessel density and endothelial cell survival. Cardiovasc Pathol (2012) 0.89
Age as a modulator of inflammatory cardiovascular risk factors. Arterioscler Thromb Vasc Biol (2011) 0.88
Lipoprotein-associated phospholipase A2 as a novel risk marker for cardiovascular disease: a systematic review of the literature. Tex Heart Inst J (2010) 0.88
The effect of acute intermittent hypercapnic hypoxia treatment on IL-6, TNF-alpha, and CRP levels in piglets. Sleep (2007) 0.88
C-Reactive protein gene variants are associated with postoperative C-reactive protein levels after coronary artery bypass surgery. BMC Med Genet (2009) 0.87
Inflammatory profiles in the non-pregnant state predict offspring birth weight at Cebu: evidence for inter-generational effects of low grade inflammation. Ann Hum Biol (2012) 0.87
Association between fasting plasma glucose and high-sensitivity C-reactive protein: gender differences in a Japanese community-dwelling population. Cardiovasc Diabetol (2011) 0.87
Critical appraisal of C-reactive protein throughout the spectrum of cardiovascular disease. Vasc Health Risk Manag (2006) 0.86
Role of systemic markers in periodontal diseases: a possible inflammatory burden and risk factor for cardiovascular diseases? Ann Med Health Sci Res (2014) 0.86
Markers of inflammation associated with plaque progression and instability in patients with carotid atherosclerosis. Mediators Inflamm (2015) 0.86
Beneficial effects of renal sympathetic denervation on cardiovascular inflammation and remodeling in essential hypertension. Clin Res Cardiol (2014) 0.85
Sex difference in the association of metabolic syndrome with high sensitivity C-reactive protein in a Taiwanese population. BMC Public Health (2010) 0.85
Biomarkers of structural remodelling and endothelial dysfunction for prediction of cardiovascular events or death in patients with atrial fibrillation. Clin Res Cardiol (2011) 0.85
Salivary lysozyme and prevalent hypertension. J Dent Res (2008) 0.85
Elevated mean arterial pressure in the ovariectomized rat was normalized by ET(A) receptor antagonist therapy: absence of cardiac hypertrophy and fibrosis. Br J Pharmacol (2002) 0.84
Reproducibility and validity of a semiquantitative food frequency questionnaire. Am J Epidemiol (1985) 26.13
Blood pressure, stroke, and coronary heart disease. Part 2, Short-term reductions in blood pressure: overview of randomised drug trials in their epidemiological context. Lancet (1990) 24.72
Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men. N Engl J Med (1997) 18.85
C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women. N Engl J Med (2000) 18.04
C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus. JAMA (2001) 15.85
Body weight and mortality among women. N Engl J Med (1995) 11.04
Validation of questionnaire information on risk factors and disease outcomes in a prospective cohort study of women. Am J Epidemiol (1986) 10.84
Intravenous and intracoronary fibrinolytic therapy in acute myocardial infarction: overview of results on mortality, reinfarction and side-effects from 33 randomized controlled trials. Eur Heart J (1985) 9.28
Postmenopausal estrogen therapy and cardiovascular disease. Ten-year follow-up from the nurses' health study. N Engl J Med (1991) 8.66
A prospective evaluation of plasma prostate-specific antigen for detection of prostatic cancer. JAMA (1995) 8.60
Lack of effect of long-term supplementation with beta carotene on the incidence of malignant neoplasms and cardiovascular disease. N Engl J Med (1996) 8.57
Test of the National Death Index. Am J Epidemiol (1984) 8.46
Dietary fat intake and the risk of coronary heart disease in women. N Engl J Med (1997) 8.43
Prevalence of Alzheimer's disease in a community population of older persons. Higher than previously reported. JAMA (1989) 8.36
Plasma concentration of interleukin-6 and the risk of future myocardial infarction among apparently healthy men. Circulation (2000) 8.17
Physical activity and incidence of non-insulin-dependent diabetes mellitus in women. Lancet (1991) 7.87
An overview of randomized trials of rehabilitation with exercise after myocardial infarction. Circulation (1989) 6.87
Plasma insulin-like growth factor-I and prostate cancer risk: a prospective study. Science (1998) 6.50
Abdominal adiposity and coronary heart disease in women. JAMA (1998) 6.21
A prospective study of cholesterol, apolipoproteins, and the risk of myocardial infarction. N Engl J Med (1991) 6.13
A prospective study of obesity and risk of coronary heart disease in women. N Engl J Med (1990) 6.06
Triggering of sudden death from cardiac causes by vigorous exertion. N Engl J Med (2000) 5.63
Vitamin E consumption and the risk of coronary disease in women. N Engl J Med (1993) 5.39
The use of a self-administered questionnaire to assess diet four years in the past. Am J Epidemiol (1988) 5.32
Tubal ligation, hysterectomy, and risk of ovarian cancer. A prospective study. JAMA (1993) 5.31
Prospective study of colorectal cancer risk in men and plasma levels of insulin-like growth factor (IGF)-I and IGF-binding protein-3. J Natl Cancer Inst (1999) 5.27
Moderate alcohol intake, increased levels of high-density lipoprotein and its subfractions, and decreased risk of myocardial infarction. N Engl J Med (1993) 5.19
Intake of trans fatty acids and risk of coronary heart disease among women. Lancet (1993) 5.00
Postmenopausal hormone therapy and mortality. N Engl J Med (1997) 4.96
A prospective evaluation of an angiotensin-converting-enzyme gene polymorphism and the risk of ischemic heart disease. N Engl J Med (1995) 4.94
Baseline characteristics of participants in the Women's Health Study. J Womens Health Gend Based Med (2000) 4.84
Dual effects of weight and weight gain on breast cancer risk. JAMA (1997) 4.81
C-reactive protein adds to the predictive value of total and HDL cholesterol in determining risk of first myocardial infarction. Circulation (1998) 4.80
Dietary fat and fiber in relation to risk of breast cancer. An 8-year follow-up. JAMA (1992) 4.80
Weight, weight change, and coronary heart disease in women. Risk within the 'normal' weight range. JAMA (1995) 4.78
Menopause and the risk of coronary heart disease in women. N Engl J Med (1987) 4.70
Prospective study of sex hormone levels and risk of prostate cancer. J Natl Cancer Inst (1996) 4.66
Weight as a risk factor for clinical diabetes in women. Am J Epidemiol (1990) 4.64
A prospective study of walking as compared with vigorous exercise in the prevention of coronary heart disease in women. N Engl J Med (1999) 4.61
A prospective study of passive smoking and coronary heart disease. Circulation (1997) 4.51
Birth weight and risk of cardiovascular disease in a cohort of women followed up since 1976. BMJ (1997) 4.49
Birthweight and the risk for type 2 diabetes mellitus in adult women. Ann Intern Med (1999) 4.49
Cigarette smoking, relative weight, and menopause. Am J Epidemiol (1983) 4.46
A prospective study of dietary glycemic load, carbohydrate intake, and risk of coronary heart disease in US women. Am J Clin Nutr (2000) 4.38
Cholesterol lowering with statin drugs, risk of stroke, and total mortality. An overview of randomized trials. JAMA (1997) 4.37
Smoking cessation and decreased risk of stroke in women. JAMA (1993) 4.36
Beta-carotene supplementation and incidence of cancer and cardiovascular disease: the Women's Health Study. J Natl Cancer Inst (1999) 4.27
PIA1/A2 polymorphism of platelet glycoprotein IIIa and risks of myocardial infarction, stroke, and venous thrombosis. Lancet (1997) 4.27
Alcohol consumption and mortality among women. N Engl J Med (1995) 4.22
Design of Physicians' Health Study II--a randomized trial of beta-carotene, vitamins E and C, and multivitamins, in prevention of cancer, cardiovascular disease, and eye disease, and review of results of completed trials. Ann Epidemiol (2000) 4.21
Fruit and vegetable intake and risk of cardiovascular disease: the Women's Health Study. Am J Clin Nutr (2000) 3.99
Plasma concentration of soluble intercellular adhesion molecule 1 and risks of future myocardial infarction in apparently healthy men. Lancet (1998) 3.97
A prospective study of plasma homocyst(e)ine and risk of myocardial infarction in US physicians. JAMA (1992) 3.96
Dietary saturated fats and their food sources in relation to the risk of coronary heart disease in women. Am J Clin Nutr (1999) 3.91
Whole-grain consumption and risk of coronary heart disease: results from the Nurses' Health Study. Am J Clin Nutr (1999) 3.89
Mutation in the gene coding for coagulation factor V and the risk of myocardial infarction, stroke, and venous thrombosis in apparently healthy men. N Engl J Med (1995) 3.88
Association of moderate alcohol consumption and plasma concentration of endogenous tissue-type plasminogen activator. JAMA (1994) 3.86
A prospective study of maturity-onset diabetes mellitus and risk of coronary heart disease and stroke in women. Arch Intern Med (1991) 3.85
Reproducibility and validity of self-reported menopausal status in a prospective cohort study. Am J Epidemiol (1987) 3.77
A prospective study of cigarette smoking and risk of cataract in men. JAMA (1992) 3.72
Implications of small reductions in diastolic blood pressure for primary prevention. Arch Intern Med (1995) 3.71
A prospective study of triglyceride level, low-density lipoprotein particle diameter, and risk of myocardial infarction. JAMA (1996) 3.69
Self-reported breast implants and connective-tissue diseases in female health professionals. A retrospective cohort study. JAMA (1996) 3.69
A prospective study of aspirin use and primary prevention of cardiovascular disease in women. JAMA (1991) 3.67
Physical activity and coronary heart disease in women: is "no pain, no gain" passé? JAMA (2001) 3.65
Serum cholesterol level and mortality findings for men screened in the Multiple Risk Factor Intervention Trial. Multiple Risk Factor Intervention Trial Research Group. Arch Intern Med (1992) 3.42
The primary prevention of coronary heart disease in women. N Engl J Med (1995) 3.40
Methylenetetrahydrofolate reductase polymorphism, dietary interactions, and risk of colorectal cancer. Cancer Res (1997) 3.36
Postmenopausal estrogen and progestin use and the risk of cardiovascular disease. N Engl J Med (1996) 3.35
A prospective study of moderate alcohol consumption and the risk of coronary disease and stroke in women. N Engl J Med (1988) 3.33
Interrelation of hyperhomocyst(e)inemia, factor V Leiden, and risk of future venous thromboembolism. Circulation (1997) 3.23
Fruit and vegetable intake in relation to risk of ischemic stroke. JAMA (1999) 3.21
Light-to-moderate alcohol consumption and risk of stroke among U.S. male physicians. N Engl J Med (1999) 3.21
A prospective study of postmenopausal estrogen therapy and coronary heart disease. N Engl J Med (1985) 3.21
A prospective study of lipoprotein(a) and the risk of myocardial infarction. JAMA (1993) 3.18
Prospective study of shift work and risk of coronary heart disease in women. Circulation (1995) 3.18
Evidence for a positive linear relation between blood pressure and mortality in elderly people. Lancet (1995) 3.14
Body weight and longevity. A reassessment. JAMA (1987) 3.13
A prospective study of risk factors for pulmonary embolism in women. JAMA (1997) 3.12
Mortality and light to moderate alcohol consumption after myocardial infarction. Lancet (1998) 3.06
Fish consumption and risk of sudden cardiac death. JAMA (1998) 3.06
A prospective study of body mass index, weight change, and risk of stroke in women. JAMA (1997) 3.04
Low-density lipoprotein subclass patterns and risk of myocardial infarction. JAMA (1988) 3.04
Dietary intake of alpha-linolenic acid and risk of fatal ischemic heart disease among women. Am J Clin Nutr (1999) 3.03
The nurses' health study. Am J Nurs (1978) 3.00
Relative and absolute excess risks of coronary heart disease among women who smoke cigarettes. N Engl J Med (1987) 2.98
Black-white inequalities in mortality and life expectancy, 1933-1999: implications for healthy people 2010. Public Health Rep (2002) 2.90
Smoking and mortality among older men and women in three communities. N Engl J Med (1991) 2.86
Plasma concentration of C-reactive protein and risk of developing peripheral vascular disease. Circulation (1998) 2.83