Published in Clin Cancer Res on September 01, 1998
Causes and consequences of aneuploidy in cancer. Nat Rev Genet (2012) 4.08
Membrane transporters and folate homeostasis: intestinal absorption and transport into systemic compartments and tissues. Expert Rev Mol Med (2009) 2.33
Methylenetetrahydrofolate reductase (MTHFR) polymorphisms and risk of molecularly defined subtypes of childhood acute leukemia. Proc Natl Acad Sci U S A (2001) 1.93
Shortening infusion time for high-dose methotrexate alters antileukemic effects: a randomized prospective clinical trial. J Clin Oncol (2011) 1.60
Folate pathway gene expression differs in subtypes of acute lymphoblastic leukemia and influences methotrexate pharmacodynamics. J Clin Invest (2005) 1.46
PharmGKB summary: methotrexate pathway. Pharmacogenet Genomics (2011) 1.27
The human reduced folate carrier gene is ubiquitously and differentially expressed in normal human tissues: identification of seven non-coding exons and characterization of a novel promoter. Biochem J (2002) 1.21
Malignancy in children with trisomy 21. Oncologist (2009) 1.12
The association of reduced folate carrier 80G>A polymorphism to outcome in childhood acute lymphoblastic leukemia interacts with chromosome 21 copy number. Blood (2010) 0.98
Roles of USF, Ikaros and Sp proteins in the transcriptional regulation of the human reduced folate carrier B promoter. Biochem J (2004) 0.94
Quantitative correlation between promoter methylation and messenger RNA levels of the reduced folate carrier. BMC Cancer (2008) 0.91
Acute leukemia in children with Down syndrome. Haematologica (2010) 0.90
Characterization of a cysteine-less human reduced folate carrier: localization of a substrate-binding domain by cysteine-scanning mutagenesis and cysteine accessibility methods. Biochem J (2003) 0.87
Expression of resistance markers to methotrexate predicts clinical improvement in patients with rheumatoid arthritis. Ann Rheum Dis (2004) 0.86
Analysis of the membrane topology for transmembrane domains 7-12 of the human reduced folate carrier by scanning cysteine accessibility methods. Biochem J (2004) 0.82
Aurea mediocritas: the importance of a balanced genome. Cold Spring Harb Perspect Biol (2014) 0.79
Expression of RFC/SLC19A1 is associated with tumor type in bladder cancer patients. PLoS One (2011) 0.77
Impact of genetic variants of RFC1, DHFR and MTHFR in osteosarcoma patients treated with high-dose methotrexate. Pharmacogenomics J (2015) 0.76
Pattern of chromosome involvement in childhood hyperdiploid pre-B-cell acute lymhoblastic leukemia cases from India. Indian J Hum Genet (2014) 0.75
A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor. Cell (1994) 5.94
Uniform approach to risk classification and treatment assignment for children with acute lymphoblastic leukemia. J Clin Oncol (1996) 5.09
Identifying proteins from two-dimensional gels by molecular mass searching of peptide fragments in protein sequence databases. Proc Natl Acad Sci U S A (1993) 4.58
Chronic pain in Australia: a prevalence study. Pain (2001) 3.83
Isolation of subgenus B adenovirus during a fatal outbreak of enterovirus 71-associated hand, foot, and mouth disease in Sibu, Sarawak. Lancet (1999) 3.21
Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand. Nature (1994) 3.13
Gradients of Intercellular CO(2) Levels Across the Leaf Mesophyll. Plant Physiol (1988) 2.93
Can coronary flow parameters after stent placement predict restenosis? Cathet Cardiovasc Diagn (1995) 2.69
Localized intracoronary gamma-radiation therapy to inhibit the recurrence of restenosis after stenting. N Engl J Med (2001) 2.54
Correlation between the Carbon Isotope Discrimination in Leaf Starch and Sugars of C(3) Plants and the Ratio of Intercellular and Atmospheric Partial Pressures of Carbon Dioxide. Plant Physiol (1988) 2.45
Racial differences in the survival of childhood B-precursor acute lymphoblastic leukemia: a Pediatric Oncology Group Study. J Clin Oncol (2000) 2.40
Red cells from glutathione peroxidase-1-deficient mice have nearly normal defenses against exogenous peroxides. Blood (2000) 2.19
One-year survival following early revascularization for cardiogenic shock. JAMA (2001) 2.10
Cloning, sequencing, and expression of a 24-kDa Ca(2+)-binding protein activating photoreceptor guanylyl cyclase. J Biol Chem (1995) 2.10
Esophageal rupture associated with the use of the Combitube. Anesth Analg (1997) 2.03
Family management in the prevention of morbidity of schizophrenia. Clinical outcome of a two-year longitudinal study. Arch Gen Psychiatry (1985) 1.99
A Chinese version of the Mini-Mental State Examination; impact of illiteracy in a Shanghai dementia survey. J Clin Epidemiol (1988) 1.96
Mismatch repair-induced meiotic recombination requires the pms1 gene product. Genetics (1990) 1.91
Long-term results of the pediatric oncology group studies for childhood acute lymphoblastic leukemia 1984-2001: a report from the children's oncology group. Leukemia (2009) 1.90
Identification and purification of human Stat proteins activated in response to interleukin-2. Immunity (1995) 1.90
Alterations in p53 and p16INK4 expression and telomere length during spontaneous immortalization of Li-Fraumeni syndrome fibroblasts. Mol Cell Biol (1995) 1.85
Preponderance of thiopurine S-methyltransferase deficiency and heterozygosity among patients intolerant to mercaptopurine or azathioprine. J Clin Oncol (2001) 1.82
Age- and sex-related changes in lymphocyte subpopulations of healthy Asian subjects: from birth to adulthood. Cytometry (1996) 1.78
Primary structure and differential expression of beta-amylase in normal and mutant barleys. Eur J Biochem (1987) 1.74
Refined crystal structure of Cd, Zn metallothionein at 2.0 A resolution. J Mol Biol (1991) 1.70
The spectrum of Evans' syndrome. Arch Dis Child (1997) 1.69
Clinical heterogeneity in childhood acute lymphoblastic leukemia with 11q23 rearrangements. Leukemia (2003) 1.64
Admission rates for peptic ulcer in the trent region, UK, 1972--2000. changing pattern, a changing disease? Dig Liver Dis (2004) 1.58
Perforin polymorphism A91V and susceptibility to B-precursor childhood acute lymphoblastic leukemia: a report from the Children's Oncology Group. Leukemia (2006) 1.57
Images in cardiovascular medicine. Calcified amorphous tumor of the heart. Circulation (2008) 1.56
Eclipse burns: a prospective study of solar retinopathy following the 1999 solar eclipse. Lancet (2001) 1.54
Improved survival for children with B-cell acute lymphoblastic leukemia and stage IV small noncleaved-cell lymphoma: a pediatric oncology group study. J Clin Oncol (1996) 1.54
Levels of p53 protein increase with maturation in human hematopoietic cells. Cancer Res (1991) 1.49
Hypomethylation of WNT5A, CRIP1 and S100P in prostate cancer. Oncogene (2007) 1.46
The impact of NOTCH1, FBW7 and PTEN mutations on prognosis and downstream signaling in pediatric T-cell acute lymphoblastic leukemia: a report from the Children's Oncology Group. Leukemia (2009) 1.45
Cognitive development and dietary therapy in phenylketonuric children. N Engl J Med (1968) 1.42
Low or absent SPARC expression in acute myeloid leukemia with MLL rearrangements is associated with sensitivity to growth inhibition by exogenous SPARC protein. Leukemia (2006) 1.42
Isolation of human cDNAs that restore methotrexate sensitivity and reduced folate carrier activity in methotrexate transport-defective Chinese hamster ovary cells. J Biol Chem (1995) 1.42
The diagnosis of tuberculous meningitis using the polymerase chain reaction. Singapore Med J (1994) 1.39
Allelotype of human bladder cancer. Cancer Res (1994) 1.38
Direct interactions of human lymphocytes with the yeast-like organism, Cryptococcus neoformans. J Clin Invest (1993) 1.38
Distinct regions of c-Mpl cytoplasmic domain are coupled to the JAK-STAT signal transduction pathway and Shc phosphorylation. Proc Natl Acad Sci U S A (1995) 1.34
Treatment of spontaneous coronary artery dissection with intracoronary stenting. Am Heart J (1996) 1.34
The cellular pharmacology of methotrexate. Pharmacol Ther (1985) 1.31
Clinical features and outcome of T-cell acute lymphoblastic leukemia in childhood with respect to alterations at the TAL1 locus: a Pediatric Oncology Group study. Blood (1993) 1.30
Impaired membrane transport in methotrexate-resistant CCRF-CEM cells involves early translation termination and increased turnover of a mutant reduced folate carrier. J Biol Chem (1999) 1.29
Value of the P-wave signal-averaged ECG for predicting atrial fibrillation after cardiac surgery. Circulation (1993) 1.26
Hemoglobin autoxidation and regulation of endogenous H2O2 levels in erythrocytes. Free Radic Biol Med (2005) 1.23
Role of MRP4 and MRP5 in biology and chemotherapy. AAPS PharmSci (2002) 1.22
Secondary cytogenetic aberrations in childhood Philadelphia chromosome positive acute lymphoblastic leukemia are nonrandom and may be associated with outcome. Leukemia (2004) 1.21
DNA amplification by the polymerase chain reaction for the rapid diagnosis of tuberculous meningitis. Comparison of protocols involving three mycobacterial DNA sequences, IS6110, 65 kDa antigen, and MPB64. J Neurol Sci (1994) 1.18
Adaptive regulation of intestinal folate uptake: effect of dietary folate deficiency. Am J Physiol Cell Physiol (2000) 1.18
The New South Wales Health Survey Program: Overview and methods, 1996-2000. N S W Public Health Bull (2001) 1.18
Myeloblasts from Down syndrome children with acute myeloid leukemia have increased in vitro sensitivity to cytosine arabinoside and daunorubicin. Leukemia (1997) 1.18
Effects of social support and relapse prevention training as adjuncts to a televised smoking-cessation intervention. J Consult Clin Psychol (1993) 1.15
Long-term results of treatment studies for childhood acute lymphoblastic leukemia: Pediatric Oncology Group studies from 1986-1994. Leukemia (2000) 1.15
Cloning of AL-1, a ligand for an Eph-related tyrosine kinase receptor involved in axon bundle formation. Neuron (1995) 1.15
Characteristics of participants in a televised smoking cessation intervention. Prev Med (1991) 1.14
Variation in the oxygen isotope ratio of phloem sap sucrose from castor bean. Evidence in support of the Péclet effect. Plant Physiol (2000) 1.12
Interactions of virulent and avirulent leptospires with primary cultures of renal epithelial cells. J Med Microbiol (1986) 1.12
Small stent size and intimal hyperplasia contribute to restenosis: a volumetric intravascular ultrasound analysis. J Am Coll Cardiol (1995) 1.12
Recharging cationic DNA complexes with highly charged polyanions for in vitro and in vivo gene delivery. Gene Ther (2003) 1.11
Glucose phosphate isomerase deficiency as a cause of hydrops fetalis. N Engl J Med (1987) 1.11
Collaborative study of children treated for phenylketonuria: study design. Pediatrics (1977) 1.10
Nitrogen Metabolism in Senescent Flag Leaves of Wheat (Triticum aestivum L.) in the Light. Plant Physiol (1985) 1.10
The adaptor protein BLNK is required for b cell antigen receptor-induced activation of nuclear factor-kappa B and cell cycle entry and survival of B lymphocytes. J Biol Chem (2001) 1.07
Comparison of DiOC(6)(3) uptake and annexin V labeling for quantification of apoptosis in leukemia cells and non-malignant T lymphocytes from children. Cytometry (2000) 1.07
Prenatal origin of childhood acute lymphoblastic leukemia, association with birth weight and hyperdiploidy. Leukemia (2008) 1.06
Chemokines: key players in cancer. Curr Med Res Opin (2003) 1.06
Effects of the loss of capacity for N-glycosylation on the transport activity and cellular localization of the human reduced folate carrier. Biochim Biophys Acta (1998) 1.05
Monoclonal antibody characterization of surface antigens in childhood T-cell lymphoid malignancies. Blood (1983) 1.04
The role of the proto-oncogene ETS2 in acute megakaryocytic leukemia biology and therapy. Leukemia (2007) 1.04
Precipitation casting of polycaprolactone for applications in tissue engineering and drug delivery. Biomaterials (2004) 1.04
Mutation of H-ras is infrequent in bladder cancer: confirmation by single-strand conformation polymorphism analysis, designed restriction fragment length polymorphisms, and direct sequencing. Cancer Res (1993) 1.04
Prognostic features in acute megakaryoblastic leukemia in children without Down syndrome: a report from the AML02 multicenter trial and the Children's Oncology Group Study POG 9421. Leukemia (2012) 1.03
Cognitive impairment among elderly adults in Shanghai, China. J Gerontol (1989) 1.03
Irreversible inactivation of bovine carbonic anhydrase B by bromoacetazolamide. J Biol Chem (1968) 1.03
Effects of elevated [CO(2)] and nitrogen nutrition on cytokinins in the xylem sap and leaves of cotton. Plant Physiol (2000) 1.02
Skin microvascular architecture and perfusion studied in human postmastectomy oedema by intravital video-capillaroscopy. Int J Microcirc Clin Exp (1995) 1.01
A novel human cell culture model for the study of familial prostate cancer. Cancer Res (2001) 1.01
Periodic transfusions for sickle cell anemia and CNS infarction. Am J Dis Child (1979) 1.00
Rhodopsin/transducin interactions. II. Influence of the transducin-beta gamma subunit complex on the coupling of the transducin-alpha subunit to rhodopsin. J Biol Chem (1992) 1.00
Intracoronary stents. A breakthrough technology or just another small step? Circulation (1994) 1.00
Human K562 transfectants expressing high levels of reduced folate carrier but exhibiting low transport activity. Biochem Pharmacol (1997) 1.00
Treatment of familial erythrophagocytic lymphohistiocytosis with cyclosporine A. J Pediatr (1997) 1.00
Phase I trial of paclitaxel in children with refractory solid tumors: a Pediatric Oncology Group Study. J Clin Oncol (1993) 0.99
Direct interactions of human natural killer cells with Cryptococcus neoformans inhibit granulocyte-macrophage colony-stimulating factor and tumor necrosis factor alpha production. Infect Immun (1997) 0.99