Carmustine and streptozocin in refractory melanoma: an attempt at modulation of O-alkylguanine-DNA-alkyltransferase.

PubWeight™: 0.89‹?›

🔗 View Article (PMID 9816278)

Published in Clin Cancer Res on July 01, 1996

Authors

D C Smith1, S L Gerson, L Liu, S Donnelly, R Day, D L Trump, J M Kirkwood

Author Affiliations

1: Division of Medical Oncology, Department of Medicine, University of Pittsburgh School of Medicine and University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania 15213, USA.

Articles by these authors

(truncated to the top 100)

Concern Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. VIGOR Study Group. N Engl J Med (2000) 29.03

Prognostic factors analysis of 17,600 melanoma patients: validation of the American Joint Committee on Cancer melanoma staging system. J Clin Oncol (2001) 10.20

Final version of the American Joint Committee on Cancer staging system for cutaneous melanoma. J Clin Oncol (2001) 9.68

Eligibility and response guidelines for phase II clinical trials in androgen-independent prostate cancer: recommendations from the Prostate-Specific Antigen Working Group. J Clin Oncol (1999) 9.22

Genetic reassortment of avian, swine, and human influenza A viruses in American pigs. J Virol (1999) 7.72

Schizophrenia: manifestations, incidence and course in different cultures. A World Health Organization ten-country study. Psychol Med Monogr Suppl (1992) 7.04

Phase III multicenter randomized trial of the Dartmouth regimen versus dacarbazine in patients with metastatic melanoma. J Clin Oncol (1999) 5.95

Hematopoietic engraftment and survival in adult recipients of umbilical-cord blood from unrelated donors. N Engl J Med (2001) 5.14

Levels of TGF-alpha and EGFR protein in head and neck squamous cell carcinoma and patient survival. J Natl Cancer Inst (1998) 5.05

Acetylation of p53 activates transcription through recruitment of coactivators/histone acetyltransferases. Mol Cell (2001) 4.73

The Elongin BC complex interacts with the conserved SOCS-box motif present in members of the SOCS, ras, WD-40 repeat, and ankyrin repeat families. Genes Dev (1998) 4.29

Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-kappaB control. Proc Natl Acad Sci U S A (1997) 4.07

Rapid hematopoietic recovery after coinfusion of autologous-blood stem cells and culture-expanded marrow mesenchymal stem cells in advanced breast cancer patients receiving high-dose chemotherapy. J Clin Oncol (2000) 3.94

Activation of CD25(+)CD4(+) regulatory T cells by oral antigen administration. J Immunol (2001) 3.86

Production of beta-defensins by human airway epithelia. Proc Natl Acad Sci U S A (1998) 3.85

Hypersensitivity reactions from taxol. J Clin Oncol (1990) 3.83

Regulation of AMPA receptor-mediated synaptic transmission by clathrin-dependent receptor internalization. Neuron (2000) 3.73

Molecular genetic analysis of oligodendroglial tumors shows preferential allelic deletions on 19q and 1p. Am J Pathol (1994) 3.66

Early manifestations and first-contact incidence of schizophrenia in different cultures. A preliminary report on the initial evaluation phase of the WHO Collaborative Study on determinants of outcome of severe mental disorders. Psychol Med (1986) 3.56

CDKN2A mutations in multiple primary melanomas. N Engl J Med (1998) 3.52

Quality-of-life-adjusted survival analysis of interferon alfa-2b adjuvant treatment of high-risk resected cutaneous melanoma: an Eastern Cooperative Oncology Group study. J Clin Oncol (1996) 3.30

Risks of untreated and treated isolated systolic hypertension in the elderly: meta-analysis of outcome trials. Lancet (2000) 3.25

Allogeneic mesenchymal stem cell infusion for treatment of metachromatic leukodystrophy (MLD) and Hurler syndrome (MPS-IH). Bone Marrow Transplant (2002) 3.24

Fas-induced caspase denitrosylation. Science (1999) 3.21

Differential regulation of circadian pacemaker output by separate clock genes in Drosophila. Proc Natl Acad Sci U S A (2000) 3.11

Phenotypic and functional comparison of cultures of marrow-derived mesenchymal stem cells (MSCs) and stromal cells. J Cell Physiol (1998) 3.08

Cooperative partnerships or conflict-of-interest? A national survey of interaction between the pharmaceutical industry and medical organizations. Intern Med J (2005) 3.08

Prolonged granulocytopenia: the major risk factor for invasive pulmonary aspergillosis in patients with acute leukemia. Ann Intern Med (1984) 3.07

Nef interacts with the mu subunit of clathrin adaptor complexes and reveals a cryptic sorting signal in MHC I molecules. Immunity (1998) 2.95

Central melanocortin receptors regulate insulin action. J Clin Invest (2001) 2.83

A synthetic HIV-1 protease inhibitor with antiviral activity arrests HIV-like particle maturation. Science (1990) 2.80

Critical residues for histone acetylation by Gcn5, functioning in Ada and SAGA complexes, are also required for transcriptional function in vivo. Genes Dev (1998) 2.76

Presence of depressive symptoms during early pregnancy and the risk of preterm delivery: a prospective cohort study. Hum Reprod (2008) 2.68

The 145-kDa protein induced to associate with Shc by multiple cytokines is an inositol tetraphosphate and phosphatidylinositol 3,4,5-triphosphate 5-phosphatase. Proc Natl Acad Sci U S A (1996) 2.68

Amplification and overexpression of the MDM2 gene in a subset of human malignant gliomas without p53 mutations. Cancer Res (1993) 2.65

Vitiligo in patients with metastatic melanoma: a good prognostic sign. J Am Acad Dermatol (1983) 2.65

The family of subtilisin/kexin like pro-protein and pro-hormone convertases: divergent or shared functions. Biochimie (1994) 2.64

Bright light treatment of winter depression: a placebo-controlled trial. Arch Gen Psychiatry (1998) 2.62

The practice of neurology, 2000-2010: report of the AAN Member Research Subcommittee. Neurology (2011) 2.59

Disproportionate distribution of Burkholderia cepacia complex species and transmissibility markers in cystic fibrosis. Am J Respir Crit Care Med (2001) 2.55

Clinical manifestations and diagnosis of acute pyrethroid poisoning. Arch Toxicol (1989) 2.50

Degradation of transcription factor RFX5 during the inhibition of both constitutive and interferon gamma-inducible major histocompatibility complex class I expression in chlamydia-infected cells. J Exp Med (2000) 2.40

Chlamydia inhibits interferon gamma-inducible major histocompatibility complex class II expression by degradation of upstream stimulatory factor 1. J Exp Med (1999) 2.39

Direct analysis and MALDI imaging of formalin-fixed, paraffin-embedded tissue sections. J Proteome Res (2007) 2.38

Marked inactivation of O6-alkylguanine-DNA alkyltransferase activity with protracted temozolomide schedules. Br J Cancer (2003) 2.38

Cutting edge: IFN-inducible ELR- CXC chemokines display defensin-like antimicrobial activity. J Immunol (2001) 2.38

Association of genetic variation in FTO with risk of obesity and type 2 diabetes with data from 96,551 East and South Asians. Diabetologia (2011) 2.37

Ex vivo expansion and subsequent infusion of human bone marrow-derived stromal progenitor cells (mesenchymal progenitor cells): implications for therapeutic use. Bone Marrow Transplant (1995) 2.35

Inactivation of Fac in mice produces inducible chromosomal instability and reduced fertility reminiscent of Fanconi anaemia. Nat Genet (1996) 2.32

PC1 and PC2 are proprotein convertases capable of cleaving proopiomelanocortin at distinct pairs of basic residues. Proc Natl Acad Sci U S A (1991) 2.27

Oncogenic RAF1 rearrangement and a novel BRAF mutation as alternatives to KIAA1549:BRAF fusion in activating the MAPK pathway in pilocytic astrocytoma. Oncogene (2009) 2.26

Improved staging of node-negative patients with intermediate to thick melanomas (>1 mm) with the use of lymphatic mapping and sentinel lymph node biopsy. Ann Surg Oncol (2001) 2.19

The Drosophila takeout gene is a novel molecular link between circadian rhythms and feeding behavior. Cell (2000) 2.18

Potentially modifiable risk factors associated with myocardial infarction in China: the INTERHEART China study. Heart (2009) 2.16

The symptoms of advanced cancer: relationship to age, gender, and performance status in 1,000 patients. Support Care Cancer (2000) 2.12

cDNA structure, tissue distribution, and chromosomal localization of rat PC7, a novel mammalian proprotein convertase closest to yeast kexin-like proteinases. Proc Natl Acad Sci U S A (1996) 2.10

One hundred ten consecutive primary orthotopic liver transplants under FK 506 in adults. Transplant Proc (1991) 2.10

Identification of Pandoraea species by 16S ribosomal DNA-based PCR assays. J Clin Microbiol (2001) 2.09

Emergence of H3N2 reassortant influenza A viruses in North American pigs. Vet Microbiol (2000) 2.06

Risk of second primary in situ and invasive melanoma in a Dutch population-based cohort: 1989-2008. Br J Dermatol (2012) 2.03

Exisulind induction of apoptosis involves guanosine 3',5'-cyclic monophosphate phosphodiesterase inhibition, protein kinase G activation, and attenuated beta-catenin. Cancer Res (2000) 2.00

Pulse pressure not mean pressure determines cardiovascular risk in older hypertensive patients. Arch Intern Med (2000) 1.99

The src homology 2-containing inositol phosphatase (SHIP) is the gatekeeper of mast cell degranulation. Proc Natl Acad Sci U S A (1998) 1.98

Base-line quality-of-life assessment in the National Surgical Adjuvant Breast and Bowel Project Breast Cancer Prevention Trial. J Natl Cancer Inst (1995) 1.94

Phase III trial of dacarbazine versus dacarbazine with interferon alpha-2b versus dacarbazine with tamoxifen versus dacarbazine with interferon alpha-2b and tamoxifen in patients with metastatic malignant melanoma: an Eastern Cooperative Oncology Group study. J Clin Oncol (1998) 1.94

Odontogenic tumours: a retrospective study of 1642 cases in a Chinese population. Int J Oral Maxillofac Surg (2006) 1.91

Role of topoisomerase II in mediating epipodophyllotoxin-induced DNA cleavage. Cancer Res (1984) 1.88

Effects of pyrethroid insecticides on subjects engaged in packaging pyrethroids. Br J Ind Med (1988) 1.87

Hepatic cytochrome P450s metabolize aristolochic acid and reduce its kidney toxicity. Kidney Int (2008) 1.86

Virus-encoded serine proteinase inhibitor SERP-1 inhibits atherosclerotic plaque development after balloon angioplasty. Circulation (1996) 1.86

Localization of human intestinal defensin 5 in Paneth cell granules. Infect Immun (1997) 1.84

Prognostic factors for survival in patients with recurrent or metastatic renal cell carcinoma. Cancer Res (1988) 1.84

Dual MET-EGFR combinatorial inhibition against T790M-EGFR-mediated erlotinib-resistant lung cancer. Br J Cancer (2008) 1.83

Coronary heart disease in China. Heart (2008) 1.82

Causes of death among people with convulsive epilepsy in rural West China: a prospective study. Neurology (2011) 1.77

An intergroup phase III randomized study of doxorubicin and dacarbazine with or without ifosfamide and mesna in advanced soft tissue and bone sarcomas. J Clin Oncol (1993) 1.76

Activation of the NF-kappaB pathway by caspase 8 and its homologs. Oncogene (2000) 1.76

Bone marrow failure in the Fanconi anemia group C mouse model after DNA damage. Blood (1998) 1.74

Interstitial hypertension in superficial metastatic melanomas in humans. Cancer Res (1991) 1.73

Subsite-specific incidence rate and stage of disease in colorectal cancer by race, gender, and age group in the United States, 1992-1997. Cancer (2001) 1.73

Human marrow-derived mesenchymal stem cells (MSCs) express hematopoietic cytokines and support long-term hematopoiesis when differentiated toward stromal and osteogenic lineages. J Hematother Stem Cell Res (2000) 1.73

Metastatic carcinoma involving the testis. Clinical and pathologic distinction from primary testicular neoplasms. Cancer (1984) 1.71

Incorporating toxicity considerations into the design of two-stage phase II clinical trials. Biometrics (1995) 1.71

Side chains that influence fidelity at the polymerase active site of Escherichia coli DNA polymerase I (Klenow fragment). J Biol Chem (1999) 1.71

Effect of cold ischemia time on the early outcome of human hepatic allografts preserved with UW solution. Transplantation (1991) 1.71

Heterozygosity for a mutation in the parkin gene leads to later onset Parkinson disease. Neurology (2003) 1.70

Chinese trial on isolated systolic hypertension in the elderly. Systolic Hypertension in China (Syst-China) Collaborative Group. Arch Intern Med (2000) 1.69

The PR domain of the Rb-binding zinc finger protein RIZ1 is a protein binding interface and is related to the SET domain functioning in chromatin-mediated gene expression. J Biol Chem (1998) 1.67

Small intestinal enteropathy with epithelial IgG and complement deposition in children with regressive autism. Mol Psychiatry (2002) 1.67

Cutaneous involvement in malignant histiocytosis. Case report and review of the literature. Arch Dermatol (1981) 1.64

Detection of the proto-oncogene eIF4E in surgical margins may predict recurrence in head and neck cancer. Oncogene (1997) 1.64

RIZ1, but not the alternative RIZ2 product of the same gene, is underexpressed in breast cancer, and forced RIZ1 expression causes G2-M cell cycle arrest and/or apoptosis. Cancer Res (1998) 1.62

The association of cardiovascular disease risk factors with abdominal obesity in Canada. Canadian Heart Health Surveys Research Group. CMAJ (1997) 1.61

Drosophila mushroom bodies are dispensable for visual, tactile, and motor learning. Learn Mem (1999) 1.60

Merosin-deficient congenital muscular dystrophy. Partial genetic correction in two mouse models. J Clin Invest (1998) 1.60

Multiple cytokines induce the tyrosine phosphorylation of Shc and its association with Grb2 in hemopoietic cells. J Biol Chem (1993) 1.60

Overexpression of Bcl-X(L) inhibits Ara-C-induced mitochondrial loss of cytochrome c and other perturbations that activate the molecular cascade of apoptosis. Cancer Res (1997) 1.60

Erythropoietin stimulates the tyrosine phosphorylation of Shc and its association with Grb2 and a 145-Kd tyrosine phosphorylated protein. Blood (1993) 1.60

Distribution of CD133 reveals glioma stem cells self-renew through symmetric and asymmetric cell divisions. Cell Death Dis (2011) 1.59

Cholesterol-lowering effect of garlic extracts and organosulfur compounds: human and animal studies. J Nutr (2001) 1.59