Published in Neuron on December 01, 1998
Hirschsprung disease, associated syndromes, and genetics: a review. J Med Genet (2001) 2.32
Persistent restoration of sensory function by immediate or delayed systemic artemin after dorsal root injury. Nat Neurosci (2008) 1.47
Sildenafil promotes neuroprotection of the pelvic ganglia neurones after bilateral cavernosal nerve resection in the rat. BJU Int (2012) 1.45
c-Jun in Schwann cells promotes axonal regeneration and motoneuron survival via paracrine signaling. J Cell Biol (2012) 1.38
The neurotrophic factor artemin promotes pancreatic cancer invasion. Ann Surg (2006) 1.22
The structure of the glial cell line-derived neurotrophic factor-coreceptor complex: insights into RET signaling and heparin binding. J Biol Chem (2008) 1.19
The neurotrophic factor artemin influences the extent of neural damage and growth in chronic pancreatitis. Gut (2006) 1.18
An enteroendocrine cell-enteric glia connection revealed by 3D electron microscopy. PLoS One (2014) 1.15
Reduced thermal sensitivity and Nav1.8 and TRPV1 channel expression in sensory neurons of aged mice. Neurobiol Aging (2005) 1.05
TPRV1 expression defines functionally distinct pelvic colon afferents. J Neurosci (2009) 1.05
Distribution and neurochemical identification of pancreatic afferents in the mouse. J Comp Neurol (2008) 1.04
A Drosophila model of multiple endocrine neoplasia type 2. Genetics (2005) 1.03
Molecular determinants of the face map development in the trigeminal brainstem. Anat Rec A Discov Mol Cell Evol Biol (2006) 1.02
Effects of cerebral ischemia in mice deficient in Persephin. Proc Natl Acad Sci U S A (2002) 0.98
The structure of GFRalpha1 domain 3 reveals new insights into GDNF binding and RET activation. EMBO J (2004) 0.96
Development of a maturing T-cell-mediated immune response in patients with idiopathic Parkinson's disease receiving r-metHuGDNF via continuous intraputaminal infusion. J Clin Immunol (2007) 0.96
Glial cell line-derived neurotrophic factor family ligands enhance capsaicin-stimulated release of calcitonin gene-related peptide from sensory neurons. Neuroscience (2009) 0.93
The differential axonal degradation of Ret accounts for cell-type-specific function of glial cell line-derived neurotrophic factor as a retrograde survival factor. J Neurosci (2010) 0.93
Making connections in the inner ear: recent insights into the development of spiral ganglion neurons and their connectivity with sensory hair cells. Semin Cell Dev Biol (2013) 0.91
Artemin induced functional recovery and reinnervation after partial nerve injury. Pain (2013) 0.91
Structure and physiology of the RET receptor tyrosine kinase. Cold Spring Harb Perspect Biol (2013) 0.90
Artemin, a glial cell line-derived neurotrophic factor family member, induces TRPM8-dependent cold pain. J Neurosci (2013) 0.88
Inhibition of TRPA1 channel activity in sensory neurons by the glial cell line-derived neurotrophic factor family member, artemin. Mol Pain (2011) 0.88
CD2AP and Cbl-3/Cbl-c constitute a critical checkpoint in the regulation of ret signal transduction. J Neurosci (2008) 0.88
New roles for glial cell line-derived neurotrophic factor and neurturin: involvement in hair cycle control. Am J Pathol (2000) 0.87
Ape1/Ref-1 induces glial cell-derived neurotropic factor (GDNF) responsiveness by upregulating GDNF receptor alpha1 expression. Mol Cell Biol (2009) 0.86
Ret-dependent and Ret-independent mechanisms of Gfl-induced sensitization. Mol Pain (2011) 0.86
Effects of NGF, NT-3 and GDNF family members on neurite outgrowth and migration from pelvic ganglia from embryonic and newborn mice. BMC Dev Biol (2008) 0.85
Signaling pathways as specific pharmacologic targets for neuroendocrine tumor therapy: RET, PI3K, MEK, growth factors, and Notch. Neuroendocrinology (2012) 0.85
Prognostic significance of the expression of GFRα1, GFRα3 and syndecan-3, proteins binding ARTEMIN, in mammary carcinoma. BMC Cancer (2013) 0.84
Characterisation of the human GFRalpha-3 locus and investigation of the gene in Hirschsprung disease. J Med Genet (2000) 0.84
Targeting eNOS and beyond: emerging heterogeneity of the role of endothelial Rho proteins in stroke protection. Expert Rev Neurother (2009) 0.84
Plasticity of TRPV1-Expressing Sensory Neurons Mediating Autonomic Dysreflexia Following Spinal Cord Injury. Front Physiol (2012) 0.84
Rac1 is a critical mediator of endothelium-derived neurotrophic activity. Sci Signal (2009) 0.83
A novel immunoprecipitation strategy identifies a unique functional mimic of the glial cell line-derived neurotrophic factor family ligands in the pathogen Trypanosoma cruzi. Infect Immun (2008) 0.82
Various penetrance of familial medullary thyroid carcinoma in patients with RET protooncogene codon 790/791 germline mutations. Ann Surg (2002) 0.82
Loss of nitrergic neurotransmission to mouse corpus cavernosum in the absence of neurturin is accompanied by increased response to acetylcholine. Br J Pharmacol (2006) 0.82
HSV-mediated transfer of artemin overcomes myelin inhibition to improve outcome after spinal cord injury. Mol Ther (2009) 0.82
Artemin growth factor increases nicotinic cholinergic receptor subunit expression and activity in nociceptive sensory neurons. Mol Pain (2014) 0.82
Characterization of axons expressing the artemin receptor in the female rat urinary bladder: a comparison with other major neuronal populations. J Comp Neurol (2014) 0.81
Effects of the neurotrophic factor artemin on sensory afferent development and sensitivity. Sheng Li Xue Bao (2008) 0.81
Peripherally increased artemin is a key regulator of TRPA1/V1 expression in primary afferent neurons. Mol Pain (2015) 0.81
Neurotrophic Factor Artemin Promotes Invasiveness and Neurotrophic Function of Pancreatic Adenocarcinoma In Vivo and In Vitro. Pancreas (2015) 0.80
Comparison of GFL-GFRalpha complexes: further evidence relating GFL bend angle to RET signalling. Acta Crystallogr Sect F Struct Biol Cryst Commun (2009) 0.79
Artemin promotes functional long-distance axonal regeneration to the brainstem after dorsal root crush. Proc Natl Acad Sci U S A (2015) 0.79
Trophic factor and hormonal regulation of neurite outgrowth in sensory neuron-like 50B11 cells. Neurosci Lett (2013) 0.79
Antidepressant-like effect of artemin in mice: a mechanism for acetyl-L-carnitine activity on depression. Psychopharmacology (Berl) (2011) 0.79
Neurotrophic factors and their effects in the treatment of multiple sclerosis. Adv Biomed Res (2015) 0.78
Deficiency of GDNF Receptor GFRα1 in Alzheimer's Neurons Results in Neuronal Death. J Neurosci (2014) 0.78
HSP90 inhibition blocks ERBB3 and RET phosphorylation in myxoid/round cell liposarcoma and causes massive cell death in vitro and in vivo. Oncotarget (2016) 0.78
Cis and trans RET signaling control the survival and central projection growth of rapidly adapting mechanoreceptors. Elife (2015) 0.78
Pharmacokinetics and pharmacodynamics of multiple doses of BG00010, a neurotrophic factor with anti-hyperalgesic effects, in patients with sciatica. Br J Clin Pharmacol (2016) 0.78
Characterization of 3'-untranslated region of the mouse GDNF gene. BMC Mol Biol (2012) 0.77
Neurotrophin selectivity in organizing topographic regeneration of nociceptive afferents. Exp Neurol (2015) 0.77
Prophylactic thyroidectomy in multiple endocrine neoplasia: the impact of molecular mechanisms of RET proto-oncogene. Langenbecks Arch Surg (2003) 0.77
Quantitative analysis of receptor tyrosine kinase-effector coupling at functionally relevant stimulus levels. J Biol Chem (2015) 0.77
Receptor tyrosine kinase signaling: regulating neural crest development one phosphate at a time. Curr Top Dev Biol (2015) 0.77
Sympathoadrenal hyperplasia causes renal malformations in Ret(MEN2B)-transgenic mice. Am J Pathol (1999) 0.77
Internalization of glial cell-derived neurotrophic factor receptor GFR alpha 1 in the absence of the ret tyrosine kinase coreceptor. Cell Mol Neurobiol (2003) 0.77
A Pdx-1-Regulated Soluble Factor Activates Rat and Human Islet Cell Proliferation. Mol Cell Biol (2016) 0.76
Early gestation chorionic villi-derived stromal cells for fetal tissue engineering. World J Stem Cells (2015) 0.76
Pheochromocytoma-associated syndromes: genes, proteins and functions of RET, VHL and SDHx. Fam Cancer (2005) 0.76
Astrocytic CCAAT/Enhancer Binding Protein δ Regulates Neuronal Viability and Spatial Learning Ability via miR-135a. Mol Neurobiol (2015) 0.76
Molecular fingerprinting delineates progenitor populations in the developing zebrafish enteric nervous system. Dev Dyn (2016) 0.75
Novel combinatorial screening identifies neurotrophic factors for selective classes of motor neurons. Proc Natl Acad Sci U S A (2017) 0.75
Identification of targets of tumor suppressor microRNA-34a using a reporter library system. Proc Natl Acad Sci U S A (2017) 0.75
Cistanche tubulosa Protects Dopaminergic Neurons through Regulation of Apoptosis and Glial Cell-Derived Neurotrophic Factor: in vivo and in vitro. Front Aging Neurosci (2016) 0.75
Inflammatory and neuropathic cold allodynia are selectively mediated by the neurotrophic factor receptor GFRα3. Proc Natl Acad Sci U S A (2016) 0.75
Prognostic significance of artemin and GFRα1 expression in laryngeal squamous cell carcinoma. Exp Ther Med (2014) 0.75
Expression of artemin and GFRα3 in an animal model of migraine: possible role in the pathogenesis of this disorder. J Headache Pain (2016) 0.75
Engineering potent long-acting variants of the Wnt inhibitor DKK2. Protein Eng Des Sel (2017) 0.75
A pair of related genes with antagonistic roles in mediating flowering signals. Science (1999) 7.51
Genetic and molecular analysis of an allelic series of cop1 mutants suggests functional roles for the multiple protein domains. Plant Cell (1994) 4.07
Inhibitors of protein synthesis and RNA synthesis prevent neuronal death caused by nerve growth factor deprivation. J Cell Biol (1988) 4.06
Fluconazole resistance in Candida glabrata. Lancet (1988) 4.05
Fluconazole resistance in Candida glabrata. Antimicrob Agents Chemother (1993) 4.04
BAX is required for neuronal death after trophic factor deprivation and during development. Neuron (1996) 4.02
Expression profiling reveals hepsin overexpression in prostate cancer. Cancer Res (2001) 3.45
Identification of the DNA binding site for NGFI-B by genetic selection in yeast. Science (1991) 3.41
Correlation between in-vitro susceptibility testing to itraconazole and in-vivo outcome of Aspergillus fumigatus infection. J Antimicrob Chemother (1997) 3.40
Luteinizing hormone deficiency and female infertility in mice lacking the transcription factor NGFI-A (Egr-1). Science (1996) 3.39
Disruption of the Jak1 gene demonstrates obligatory and nonredundant roles of the Jaks in cytokine-induced biologic responses. Cell (1998) 3.25
IB4-binding DRG neurons switch from NGF to GDNF dependence in early postnatal life. Neuron (1997) 3.21
Nature of lactose-fermenting Salmonella strains obtained from clinical sources. J Bacteriol (1969) 3.14
Induction of BIM, a proapoptotic BH3-only BCL-2 family member, is critical for neuronal apoptosis. Neuron (2001) 3.07
Intergeneric bacterial matings. Bacteriol Rev (1968) 2.94
Correlation of MIC with outcome for Candida species tested against voriconazole: analysis and proposal for interpretive breakpoints. J Clin Microbiol (2006) 2.86
DNA-binding specificity of NGFI-A and related zinc finger transcription factors. Mol Cell Biol (1995) 2.78
In vitro studies of activity of voriconazole (UK-109,496), a new triazole antifungal agent, against emerging and less-common mold pathogens. Antimicrob Agents Chemother (1997) 2.75
Altered gene expression in neurons during programmed cell death: identification of c-jun as necessary for neuronal apoptosis. J Cell Biol (1994) 2.75
Skeletal malformations caused by overexpression of Cbfa1 or its dominant negative form in chondrocytes. J Cell Biol (2001) 2.73
Temporal analysis of events associated with programmed cell death (apoptosis) of sympathetic neurons deprived of nerve growth factor. J Cell Biol (1993) 2.67
Caspase inhibitor affords neuroprotection with delayed administration in a rat model of neonatal hypoxic-ischemic brain injury. J Clin Invest (1998) 2.64
Aspergillus antigen latex test for diagnosis of invasive aspergillosis. Lancet (1991) 2.59
FASCIATA genes for chromatin assembly factor-1 in arabidopsis maintain the cellular organization of apical meristems. Cell (2001) 2.56
Analysis of cell cycle-related gene expression in postmitotic neurons: selective induction of Cyclin D1 during programmed cell death. Neuron (1994) 2.54
NAB2, a corepressor of NGFI-A (Egr-1) and Krox20, is induced by proliferative and differentiative stimuli. Mol Cell Biol (1996) 2.51
Evidence of a novel event during neuronal death: development of competence-to-die in response to cytoplasmic cytochrome c. Neuron (1998) 2.49
In-vitro resistance to imidazole antifungals in Candida albicans. J Antimicrob Chemother (1984) 2.43
Prognostic significance of blood pressure and heart rate variabilities: the Ohasama study. Hypertension (2000) 2.35
GFR alpha1-deficient mice have deficits in the enteric nervous system and kidneys. Neuron (1998) 2.29
Management and outcome of bloodstream infections due to Candida species in England and Wales. J Hosp Infect (2003) 2.29
Gene targeting reveals a critical role for neurturin in the development and maintenance of enteric, sensory, and parasympathetic neurons. Neuron (1999) 2.22
Sensory ataxia and muscle spindle agenesis in mice lacking the transcription factor Egr3. Nat Genet (1998) 2.19
Genetic analysis of the ViA-his chromosomal region in Salmonella. J Bacteriol (1966) 2.17
Azole resistance in Candida albicans. J Med Vet Mycol (1986) 2.17
Characterization of transmissible genetic elements from sucrose-fermenting Salmonella strains. J Bacteriol (1975) 2.11
An initiation zone of chromosomal DNA replication located upstream of the c-myc gene in proliferating HeLa cells. Mol Cell Biol (1990) 2.08
EGR2 mutations in inherited neuropathies dominant-negatively inhibit myelin gene expression. Neuron (2001) 2.08
Participation of non-zinc finger residues in DNA binding by two nuclear orphan receptors. Science (1992) 2.08
Characteristics of the clinical findings in patients with idiopathic thrombocytopenic purpura who are positive for anti-phospholipid antibodies. Intern Med (1997) 2.07
Induction of nerve growth factor receptor in Schwann cells after axotomy. Proc Natl Acad Sci U S A (1986) 2.06
Mechanism of tolerance development to organic nitrates. J Pharmacol Exp Ther (1973) 2.04
Nerve growth factor deprivation results in the reactivation of latent herpes simplex virus in vitro. J Virol (1987) 2.01
BH3-only Bcl-2 family members are coordinately regulated by the JNK pathway and require Bax to induce apoptosis in neurons. J Biol Chem (2001) 2.01
Cloning and expression of a developmentally regulated protein that induces mitogenic and neurite outgrowth activity. Science (1990) 2.00
The HeLa Pur factor binds single-stranded DNA at a specific element conserved in gene flanking regions and origins of DNA replication. Mol Cell Biol (1992) 2.00
Wild-type MIC distribution and epidemiological cutoff values for Aspergillus fumigatus and three triazoles as determined by the Clinical and Laboratory Standards Institute broth microdilution methods. J Clin Microbiol (2009) 1.99
The orphan receptors NGFI-B and steroidogenic factor 1 establish monomer binding as a third paradigm of nuclear receptor-DNA interaction. Mol Cell Biol (1993) 1.98
Superoxide dismutase delays neuronal apoptosis: a role for reactive oxygen species in programmed neuronal death. Neuron (1995) 1.95
Mice deficient in the orphan receptor steroidogenic factor 1 lack adrenal glands and gonads but express P450 side-chain-cleavage enzyme in the placenta and have normal embryonic serum levels of corticosteroids. Proc Natl Acad Sci U S A (1995) 1.95
Unimpaired thymic and peripheral T cell death in mice lacking the nuclear receptor NGFI-B (Nur77). Science (1995) 1.93
Resistance to Fas-mediated apoptosis: activation of caspase 3 is regulated by cell cycle regulator p21WAF1 and IAP gene family ILP. Oncogene (1998) 1.92
Identification of NAB1, a repressor of NGFI-A- and Krox20-mediated transcription. Proc Natl Acad Sci U S A (1995) 1.89
Bax deletion further orders the cell death pathway in cerebellar granule cells and suggests a caspase-independent pathway to cell death. J Cell Biol (1997) 1.89
The early response gene NGFI-C encodes a zinc finger transcriptional activator and is a member of the GCGGGGGCG (GSG) element-binding protein family. Mol Cell Biol (1991) 1.88
The GDNF family ligands and receptors - implications for neural development. Curr Opin Neurobiol (2000) 1.88
RET signaling is essential for migration, axonal growth and axon guidance of developing sympathetic neurons. Development (2001) 1.86
Comparison of E-test and broth microdilution methods for antifungal drug susceptibility testing of molds. J Clin Microbiol (1999) 1.85
Neurturin, a relative of glial-cell-line-derived neurotrophic factor. Nature (1996) 1.83
Reversible changes in nucleosome structure and histone H3 accessibility in transcriptionally active and inactive states of rDNA chromatin. Cell (1983) 1.82
A region of consistent deletion in neuroblastoma maps within human chromosome 1p36.2-36.3. Proc Natl Acad Sci U S A (1995) 1.82
Frequent loss of PTEN expression is linked to elevated phosphorylated Akt levels, but not associated with p27 and cyclin D1 expression, in primary epithelial ovarian carcinomas. Am J Pathol (2001) 1.82
Dynamics of neural crest-derived cell migration in the embryonic mouse gut. Dev Biol (2004) 1.81
Amyotrophic lateral sclerosis: T2 shortening in motor cortex at MR imaging. Radiology (1993) 1.81
Diffusion-weighted MR imaging with a single-shot echoplanar sequence: detection and characterization of focal hepatic lesions. AJR Am J Roentgenol (1998) 1.80
EGR1 target genes in prostate carcinoma cells identified by microarray analysis. J Biol Chem (2000) 1.80
Growth and differentiation proceeds normally in cells deficient in the immediate early gene NGFI-A. J Biol Chem (1995) 1.77
Effects of sugar on vegetative development and floral transition in Arabidopsis. Plant Physiol (2001) 1.75
Assay of typhoid vaccines with Salmonella typhosa-Salmonella typhimurium hybrids. Infect Immun (1973) 1.72
Differential expression of pleiotrophin and midkine in advanced neuroblastomas. Cancer Res (1995) 1.72
Complex formation between lamin A and the retinoblastoma gene product: identification of the domain on lamin A required for its interaction. Oncogene (1994) 1.71
Nerve growth factor-dependence of herpes simplex virus latency in peripheral sympathetic and sensory neurons in vitro. J Neurosci (1990) 1.69
A reevaluation of risk of in utero exposure to lithium. JAMA (1994) 1.68
Expression of neurturin, GDNF, and GDNF family-receptor mRNA in the developing and mature mouse. Exp Neurol (1999) 1.67
Ninjurin, a novel adhesion molecule, is induced by nerve injury and promotes axonal growth. Neuron (1996) 1.67
Organic nitrates: relationship between biotransformation and rational angina pectoris therapy. J Pharmacol Exp Ther (1972) 1.67
Nuclear receptor DAX-1 recruits nuclear receptor corepressor N-CoR to steroidogenic factor 1. Mol Cell Biol (1998) 1.64
Adenosine 3',5-monophosphate-dependent phosphorylation of a specific protein in synaptic membrane fractions from rat cerebrum. J Biol Chem (1972) 1.63
N (epsilon)-(carboxymethyl)lysine protein adduct is a major immunological epitope in proteins modified with advanced glycation end products of the Maillard reaction. Biochemistry (1996) 1.63
Toxic gas generation from plastic mattresses and sudden infant death syndrome. Lancet (1995) 1.60
Accuracy of screening for gastric cancer using serum pepsinogen concentrations. Gut (1999) 1.60
Neurites can remain viable after destruction of the neuronal soma by programmed cell death (apoptosis). Dev Biol (1994) 1.59