Recognition of DNA alterations by the mismatch repair system.

PubWeight™: 1.08‹?› | Rank: Top 10%

🔗 View Article (PMC 1220017)

Published in Biochem J on February 15, 1999

Authors

G Marra1, P Schär

Author Affiliations

1: Institute for Medical Radiobiology, Zürich, Switzerland.

Articles citing this

DNA bending and unbending by MutS govern mismatch recognition and specificity. Proc Natl Acad Sci U S A (2003) 1.92

PCR amplification introduces errors into mononucleotide and dinucleotide repeat sequences. Mol Pathol (2001) 1.67

Whole-exome sequencing of human pancreatic cancers and characterization of genomic instability caused by MLH1 haploinsufficiency and complete deficiency. Genome Res (2011) 1.47

Novel DNA mismatch-repair activity involving YB-1 in human mitochondria. DNA Repair (Amst) (2009) 1.18

Novel recurrently mutated genes and a prognostic mutation signature in colorectal cancer. Gut (2014) 1.18

Structural and functional divergence of MutS2 from bacterial MutS1 and eukaryotic MSH4-MSH5 homologs. J Bacteriol (2005) 1.16

Expression of hepatitis B virus X protein does not alter the accumulation of spontaneous mutations in transgenic mice. J Virol (2000) 1.08

DNA pairing is an important step in the process of targeted nucleotide exchange. Nucleic Acids Res (2003) 0.95

Characterization of the mycobacterial NER system reveals novel functions of the uvrD1 helicase. J Bacteriol (2008) 0.93

Control of GT repeat stability in Schizosaccharomyces pombe by mismatch repair factors. Genetics (2001) 0.89

DNA bending propensity in the presence of base mismatches: implications for DNA repair. J Phys Chem B (2013) 0.88

Mutational profiling of colorectal cancers with microsatellite instability. Oncotarget (2015) 0.85

Evidence for widespread convergent evolution around human microsatellites. PLoS Biol (2004) 0.85

Heterogeneous nature and distribution of interruptions in dinucleotides may indicate the existence of biased substitutions underlying microsatellite evolution. J Mol Evol (2008) 0.82

Overview for the histone codes for DNA repair. Prog Mol Biol Transl Sci (2012) 0.81

Short-patch correction of C/C mismatches in human cells. Nucleic Acids Res (2004) 0.81

Recognition and binding of mismatch repair proteins at an oncogenic hot spot. BMC Mol Biol (2005) 0.80

Molecular electrostatic potentials of DNA base-base pairing and mispairing. J Mol Model (2011) 0.78

Familial colorectal cancer: eleven years of data from a registry program in Switzerland. Fam Cancer (2011) 0.77

Articles cited by this

(truncated to the top 100)

Clues to the pathogenesis of familial colorectal cancer. Science (1993) 14.52

Microsatellite instability in cancer of the proximal colon. Science (1993) 14.51

The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer. Cell (1993) 13.54

Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis. Nature (1993) 12.74

Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer. Cell (1993) 9.93

Biochemistry and genetics of eukaryotic mismatch repair. Genes Dev (1996) 9.64

Mechanisms and biological effects of mismatch repair. Annu Rev Genet (1991) 7.86

Different base/base mismatches are corrected with different efficiencies by the methyl-directed DNA mismatch-repair system of E. coli. Cell (1984) 7.26

Base-base mismatches. Thermodynamics of double helix formation for dCA3XA3G + dCT3YT3G (X, Y = A,C,G,T). Nucleic Acids Res (1985) 7.19

Pleiotropic effects of a DNA adenine methylation mutation (dam-3) in Escherichia coli K12. Mutat Res (1975) 6.18

Fidelity mechanisms in DNA replication. Annu Rev Biochem (1991) 5.93

Repair tracts in mismatched DNA heteroduplexes. Proc Natl Acad Sci U S A (1976) 5.88

Bacterial mutator genes and the control of spontaneous mutation. Annu Rev Genet (1976) 5.53

Effects of high levels of DNA adenine methylation on methyl-directed mismatch repair in Escherichia coli. Genetics (1983) 5.43

Redundancy of Saccharomyces cerevisiae MSH3 and MSH6 in MSH2-dependent mismatch repair. Genes Dev (1996) 5.34

Methyl-directed repair of DNA base-pair mismatches in vitro. Proc Natl Acad Sci U S A (1983) 5.34

DNA mismatch correction in a defined system. Science (1989) 4.98

Heteroduplex deoxyribonucleic acid base mismatch repair in bacteria. Microbiol Rev (1986) 4.74

Escherichia coli mutS-encoded protein binds to mismatched DNA base pairs. Proc Natl Acad Sci U S A (1986) 4.71

Isolation of an hMSH2-p160 heterodimer that restores DNA mismatch repair to tumor cells. Science (1995) 4.48

Requirement for PCNA in DNA mismatch repair at a step preceding DNA resynthesis. Cell (1996) 4.47

Strand-specific mismatch correction in nuclear extracts of human and Drosophila melanogaster cell lines. Proc Natl Acad Sci U S A (1990) 4.33

Characterization of insertion mutations in the Saccharomyces cerevisiae MSH1 and MSH2 genes: evidence for separate mitochondrial and nuclear functions. Genetics (1992) 3.97

Repair of defined single base-pair mismatches in Escherichia coli. Proc Natl Acad Sci U S A (1985) 3.88

Marker discrimination in transformation and mutation of pneumococcus. Proc Natl Acad Sci U S A (1973) 3.68

Identification and characterization of Saccharomyces cerevisiae EXO1, a gene encoding an exonuclease that interacts with MSH2. Proc Natl Acad Sci U S A (1997) 3.66

Human chromosome 3 corrects mismatch repair deficiency and microsatellite instability and reduces N-methyl-N'-nitro-N-nitrosoguanidine tolerance in colon tumor cells with homozygous hMLH1 mutation. Cancer Res (1994) 3.63

hMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6. Proc Natl Acad Sci U S A (1996) 3.60

GTBP, a 160-kilodalton protein essential for mismatch-binding activity in human cells. Science (1995) 3.34

Heteroduplex DNA correction in Saccharomyces cerevisiae is mismatch specific and requires functional PMS genes. Mol Cell Biol (1989) 3.28

Mutations of GTBP in genetically unstable cells. Science (1995) 3.23

Isolation and characterization of the Escherichia coli mutL gene product. J Biol Chem (1989) 3.22

Repair of DNA heteroduplexes containing small heterologous sequences in Escherichia coli. Proc Natl Acad Sci U S A (1992) 3.21

Different base/base mispairs are corrected with different efficiencies and specificities in monkey kidney cells. Cell (1988) 3.18

Heteroduplex repair in extracts of human HeLa cells. J Biol Chem (1991) 3.13

An alkylation-tolerant, mutator human cell line is deficient in strand-specific mismatch repair. Proc Natl Acad Sci U S A (1993) 3.07

Identification of base mismatches recognized by the heteroduplex-DNA-repair system of Streptococcus pneumoniae. Cell (1982) 3.06

Escherichia coli mutants uvr D and uvr E deficient in gene conversion of lambda-heteroduplexes. Mol Gen Genet (1975) 3.03

Structure of an adenine-cytosine base pair in DNA and its implications for mismatch repair. Nature (1986) 3.00

The formation, isolation and characterization of DNA adducts produced by anticancer platinum complexes. Pharmacol Ther (1987) 2.96

Isolation and characterization of the Escherichia coli mutH gene product. J Biol Chem (1987) 2.94

Initiation of methyl-directed mismatch repair. J Biol Chem (1992) 2.82

Specific binding of chromosomal protein HMG1 to DNA damaged by the anticancer drug cisplatin. Science (1992) 2.79

Mismatches in DNA double strands: thermodynamic parameters and their correlation to repair efficiencies. Nucleic Acids Res (1986) 2.73

Requirement of the yeast MSH3 and MSH6 genes for MSH2-dependent genomic stability. J Biol Chem (1996) 2.72

In vitro correction of G.T mispairs to G.C pairs in nuclear extracts from human cells. Nature (1989) 2.68

The human mismatch recognition complex hMSH2-hMSH6 functions as a novel molecular switch. Cell (1997) 2.64

Hereditary nonpolyposis colorectal cancer: the syndrome, the genes, and historical perspectives. J Natl Cancer Inst (1995) 2.62

Activation of programmed cell death (apoptosis) by cisplatin, other anticancer drugs, toxins and hyperthermia. Biochem Pharmacol (1990) 2.60

Human MutSalpha recognizes damaged DNA base pairs containing O6-methylguanine, O4-methylthymine, or the cisplatin-d(GpG) adduct. Proc Natl Acad Sci U S A (1996) 2.57

Defective mismatch binding and a mutator phenotype in cells tolerant to DNA damage. Nature (1993) 2.57

MutS mediates heteroduplex loop formation by a translocation mechanism. EMBO J (1997) 2.52

hMutSbeta, a heterodimer of hMSH2 and hMSH3, binds to insertion/deletion loops in DNA. Curr Biol (1996) 2.50

Mismatch correction in pneumococcal transformation: donor length and hex-dependent marker efficiency. J Bacteriol (1976) 2.47

A role for exonuclease I from S. pombe in mutation avoidance and mismatch correction. Science (1995) 2.46

Molecular structure of the G.A base pair in DNA and its implications for the mechanism of transversion mutations. Proc Natl Acad Sci U S A (1986) 2.46

Human strand-specific mismatch repair occurs by a bidirectional mechanism similar to that of the bacterial reaction. J Biol Chem (1993) 2.38

Loss of DNA mismatch repair in acquired resistance to cisplatin. Cancer Res (1996) 2.37

Cellular responses to cisplatin. The roles of DNA-binding proteins and DNA repair. J Biol Chem (1994) 2.36

Cisplatin and DNA repair in cancer chemotherapy. Trends Biochem Sci (1995) 2.36

Altering the conserved nucleotide binding motif in the Salmonella typhimurium MutS mismatch repair protein affects both its ATPase and mismatch binding activities. EMBO J (1991) 2.34

Specificity of mismatch repair following transformation of Saccharomyces cerevisiae with heteroduplex plasmid DNA. Proc Natl Acad Sci U S A (1989) 2.33

Mismatch correction at O6-methylguanine residues in E. coli DNA. Nature (1982) 2.33

A specific mismatch repair event protects mammalian cells from loss of 5-methylcytosine. Cell (1987) 2.30

Mutations in the MSH3 gene preferentially lead to deletions within tracts of simple repetitive DNA in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1995) 2.29

Methyl-directed mismatch repair is bidirectional. J Biol Chem (1993) 2.26

Repair of specific base pair mismatches formed during meiotic recombination in the yeast Saccharomyces cerevisiae. Mol Cell Biol (1991) 2.23

Escherichia coli K-12 clones that overproduce dam methylase are hypermutable. J Bacteriol (1981) 2.21

DNA loop repair by human cell extracts. Science (1994) 2.19

Evidence for a connection between the mismatch repair system and the G2 cell cycle checkpoint. Cancer Res (1995) 2.17

Bromouracil mutagenesis and mismatch repair in mutator strains of Escherichia coli. Mutat Res (1978) 2.17

Repair of cisplatin--DNA adducts by the mammalian excision nuclease. Biochemistry (1996) 2.17

Analysis of incision sites produced by human cell extracts and purified proteins during nucleotide excision repair of a 1,3-intrastrand d(GpTpG)-cisplatin adduct. J Biol Chem (1996) 2.13

ATP-dependent interaction of human mismatch repair proteins and dual role of PCNA in mismatch repair. Nucleic Acids Res (1998) 2.09

The Saccharomyces cerevisiae Msh2 protein specifically binds to duplex oligonucleotides containing mismatched DNA base pairs and insertions. Genes Dev (1995) 2.06

Nucleotide sequence of the hexA gene for DNA mismatch repair in Streptococcus pneumoniae and homology of hexA to mutS of Escherichia coli and Salmonella typhimurium. J Bacteriol (1988) 2.05

GATC sequences, DNA nicks and the MutH function in Escherichia coli mismatch repair. EMBO J (1987) 2.05

Isolation and characterization of human cDNA clones encoding a high mobility group box protein that recognizes structural distortions to DNA caused by binding of the anticancer agent cisplatin. Proc Natl Acad Sci U S A (1992) 2.04

Nucleotide sequence of the Salmonella typhimurium mutS gene required for mismatch repair: homology of MutS and HexA of Streptococcus pneumoniae. J Bacteriol (1988) 2.03

Cisplatin and adriamycin resistance are associated with MutLalpha and mismatch repair deficiency in an ovarian tumor cell line. J Biol Chem (1996) 2.01

Characterization of the adducts produced in DNA by cis-diamminedichloroplatinum(II) and cis-dichloro(ethylenediamine)platinum(II). Biochemistry (1983) 1.96

Cancer of the microsatellite mutator phenotype. Biol Chem (1996) 1.91

Some mismatch repair activities in Escherichia coli. Proc Natl Acad Sci U S A (1988) 1.87

The Saccharomyces cerevisiae Msh2 and Msh6 proteins form a complex that specifically binds to duplex oligonucleotides containing mismatched DNA base pairs. Mol Cell Biol (1996) 1.86

Binding of the antitumor drug cis-diamminedichloroplatinum(II) (cisplatin) to DNA. Biochim Biophys Acta (1985) 1.85

Binding of insertion/deletion DNA mismatches by the heterodimer of yeast mismatch repair proteins MSH2 and MSH3. Curr Biol (1996) 1.84

Isolation and characterization of cDNA clones derived from the divergently transcribed gene in the region upstream from the human dihydrofolate reductase gene. J Biol Chem (1989) 1.83

Recognition and repair of compound DNA lesions (base damage and mismatch) by human mismatch repair and excision repair systems. Mol Cell Biol (1997) 1.79

Mismatch repair of deaminated 5-methyl-cytosine. J Mol Biol (1987) 1.77

Enhanced DNA repair as a mechanism of resistance to cis-diamminedichloroplatinum(II). Biochemistry (1988) 1.76

Local destabilisation of a DNA double helix by a T--T wobble pair. Nature (1979) 1.76

DNA mismatch binding defects, DNA damage tolerance, and mutator phenotypes in human colorectal carcinoma cell lines. Cancer Res (1995) 1.64

Microsatellite instability, apoptosis, and loss of p53 function in drug-resistant tumor cells. Cancer Res (1996) 1.63

DNA polymerase delta is required for human mismatch repair in vitro. J Biol Chem (1997) 1.61

hMSH2 and hMSH6 play distinct roles in mismatch binding and contribute differently to the ATPase activity of hMutSalpha. EMBO J (1998) 1.60

DHFR/MSH3 amplification in methotrexate-resistant cells alters the hMutSalpha/hMutSbeta ratio and reduces the efficiency of base-base mismatch repair. Proc Natl Acad Sci U S A (1997) 1.58

Mismatch repair deficiency associated with overexpression of the MSH3 gene. Proc Natl Acad Sci U S A (1998) 1.56

Self-destruction and tolerance in resistance of mammalian cells to alkylation damage. Nucleic Acids Res (1992) 1.54

Enhancement of MSH2-MSH3-mediated mismatch recognition by the yeast MLH1-PMS1 complex. Curr Biol (1997) 1.54

A human 200-kDa protein binds selectively to DNA fragments containing G.T mismatches. Proc Natl Acad Sci U S A (1988) 1.54

Articles by these authors

Reconstitution of DNA base excision-repair with purified human proteins: interaction between DNA polymerase beta and the XRCC1 protein. EMBO J (1996) 4.89

Molecular cloning and expression of human cDNAs encoding a novel DNA ligase IV and DNA ligase III, an enzyme active in DNA repair and recombination. Mol Cell Biol (1995) 2.61

NEJ1 controls non-homologous end joining in Saccharomyces cerevisiae. Nature (2001) 2.42

Involvement of nucleotide-excision repair in msh2 pms1-independent mismatch repair. Nat Genet (1999) 2.06

Separating substrate recognition from base hydrolysis in human thymine DNA glycosylase by mutational analysis. J Biol Chem (2000) 2.03

Saccharomyces cerevisiae LIF1: a function involved in DNA double-strand break repair related to mammalian XRCC4. EMBO J (1998) 2.03

Identification of hMutLbeta, a heterodimer of hMLH1 and hPMS1. J Biol Chem (1999) 1.62

Thymine DNA glycosylase. Prog Nucleic Acid Res Mol Biol (2001) 1.19

Biochemical characterization of uracil processing activities in the hyperthermophilic archaeon Pyrobaculum aerophilum. J Biol Chem (2001) 1.12

Surgical treatment of Zenker's diverticulum: transcutaneous diverticulectomy versus microendoscopic myotomy of the cricopharyngeal muscle with CO2 laser. Otolaryngol Head Neck Surg (1999) 1.04

Normal colorectal mucosa exhibits sex- and segment-specific susceptibility to DNA methylation at the hMLH1 and MGMT promoters. Oncogene (2008) 1.03

DNA Repair in mammalian cells: Mismatched repair: variations on a theme. Cell Mol Life Sci (2009) 1.01

Regulation of DNA metabolic enzymes upon induction of preB cell development and V(D)J recombination: up-regulation of DNA polymerase delta. Nucleic Acids Res (1997) 0.87

The mutator gene swi8 effects specific mutations in the mating-type region of Schizosaccharomyces pombe. Genetics (1994) 0.83

Endonasal and transcanalicular Er:YAG laser dacryocystorhinostomy. Rhinology (2001) 0.83

Identification of two mismatch-binding activities in protein extracts of Schizosaccharomyces pombe. Nucleic Acids Res (1994) 0.82

Repair and processing events at DNA ends. Ciba Found Symp (1997) 0.78

[Work time. The hospital administrator: instead of a general reduction fewer hours overtime and oriented continued education]. Krankenpfl Soins Infirm (1984) 0.75