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Top papers

Rank Title Journal Year PubWeight™‹?›
1 HIV-1-specific CD4+ T cells are detectable in most individuals with active HIV-1 infection, but decline with prolonged viral suppression. Nat Med 1999 7.77
2 Use of overlapping peptide mixtures as antigens for cytokine flow cytometry. J Immunol Methods 2001 4.25
3 Determination of antigen-specific memory/effector CD4+ T cell frequencies by flow cytometry: evidence for a novel, antigen-specific homeostatic mechanism in HIV-associated immunodeficiency. J Clin Invest 1997 4.01
4 Direct demonstration of cytokine synthesis heterogeneity among human memory/effector T cells by flow cytometry. Blood 1995 3.12
5 Normal human CD4+ memory T cells display broad heterogeneity in their activation threshold for cytokine synthesis. J Immunol 1998 2.12
6 Detection of antigen-specific T cell cytokine expression in whole blood by flow cytometry. J Immunol Methods 1998 2.10
7 The role of calcium ions in initiating transformation of lymphocytes. Nature 1974 2.01
8 Frequencies of memory T cells specific for varicella-zoster virus, herpes simplex virus, and cytomegalovirus by intracellular detection of cytokine expression. J Infect Dis 2000 1.81
9 Relationship between enhanced turnover of phosphatidylinositol and lymphocyte activation by mitogens. Biochem J 1975 1.67
10 Mitogen activation of human chronic lymphatic leukemia cells. I. Synthesis and secretion of immunoglobulin. J Immunol 1977 1.52
11 CD4(+)CD8(dim) T lymphocytes exhibit enhanced cytokine expression, proliferation and cytotoxic activity in response to HCMV and HIV-1 antigens. Eur J Immunol 2001 1.43
12 Immunofluorescence analysis of T-cell responses in health and disease. J Clin Immunol 2000 1.29
13 Bacteriophage resistance in Bacillus subtilis 168, W23, and interstrain transformants. J Bacteriol 1976 1.26
14 Clonotypic structure of the human CD4+ memory T cell response to cytomegalovirus. J Immunol 2001 1.19
15 Mechanism of Thy-1-mediated T cell activation: roles of Fc receptors, T200, Ia, and H-2 glycoproteins in accessory cell function. J Immunol 1981 1.12
16 Factors affecting the efficiency of CD8+ T cell cross-priming with exogenous antigens. J Immunol 2001 1.11
17 A 15-year follow-up of AJCC stage III malignant melanoma patients treated postsurgically with Newcastle disease virus (NDV) oncolysate and determination of alterations in the CD8 T cell repertoire. Mol Med 1998 1.04
18 The CD4(+) T cell response to HIV-1. Curr Opin Immunol 2000 1.02
19 Activated T cells and monocytes have characteristic patterns of class II antigen expression. J Immunol 1988 1.01
20 Simultaneous detection of DNA synthesis and cytokine production in staphylococcal enterotoxin B activated CD4+ T lymphocytes by flow cytometry. J Immunol Methods 1997 1.00
21 Gamma interferon expression in CD8(+) T cells is a marker for circulating cytotoxic T lymphocytes that recognize an HLA A2-restricted epitope of human cytomegalovirus phosphoprotein pp65. Clin Diagn Lab Immunol 2001 1.00
22 Anti-Thy-1-mediated T cell activation. Role of soluble factors and expression of interleukin 2 receptors on T cells. Eur J Immunol 1981 0.94
23 Epitopes of human immunodeficiency virus type 1 (HIV-1) envelope glycoproteins recognized by antibodies in the sera of HIV-1-infected individuals. Clin Immunol Immunopathol 1991 0.89
24 Regulation of glucosylation of teichoic acid. I. Isolation of phosphoglucomutase in Bacillus subtilis 168. J Biol Chem 1974 0.89
25 Flow cytometric measurement of intracellular cytokines detects immune responses in MUC1 immunotherapy. Clin Cancer Res 2000 0.89
26 Measurement of CD69 induction in the assessment of immune function in asymptomatic HIV-infected individuals. Cytometry 1997 0.87
27 Structural characterization of a cross-reactive idiotype shared by monoclonal antibodies specific for the human CD4 molecule. J Biol Chem 1991 0.85
28 Decreased HIV-specific CD4 T cell proliferation in long-term HIV-infected individuals on antiretroviral therapy. AIDS 2001 0.84
29 In vitro activation of T lymphocytes from human immunodeficiency virus (HIV)-seropositive blood donors. I. Soluble interleukin 2 receptor (IL2R) production parallels cellular IL2R expression and DNA synthesis. J Clin Immunol 1988 0.84
30 Monoclonal antibodies, L-35 and L-36, define novel T cell activation antigens. J Immunol 1986 0.84
31 Regulation of glucosylation of teichoic acid. II. Partial characterization of phosphoglucomutase in Bacillus subtilis 168. J Biol Chem 1974 0.83
32 Direct functional analysis of epitope-specific CD8+ T cells in peripheral blood. Viral Immunol 2001 0.83
33 Mechanisms controlling TCGF production by cloned sublines of EL-4 azgr in response to stimulation by anti-Thy-1 antibody. J Immunol 1982 0.83
34 Mechanisms of TCGF production by cloned T-cell lines: characterization of producer lymphoma lines and kinetics of production. Clin Immunol Immunopathol 1982 0.82
35 Decreased expression of IL-2 in central and effector CD4 memory cells during progression to AIDS in rhesus macaques. AIDS 2001 0.79
36 Anti-idiotypic antibodies of a predefined specificity generated against CDR3VH synthetic peptides define a private anti-CD4 idiotype. Mol Immunol 1990 0.78
37 Assessment of donor T-cell function in cellular blood components by the CD69 induction assay: effects of storage, gamma radiation, and photochemical treatment. Transfusion 2000 0.78
38 Induction of interleukin 2 from a murine B cell tumor by a factor found in immune serum. J Immunol 1985 0.77
39 Recognition at cell surfaces: phytohaemagglutinin-lymphocyte interaction. Philos Trans R Soc Lond B Biol Sci 1975 0.77
40 Analysis of IL-2 producing subsets of human lymphocytes. Lymphokine Res 1986 0.75