An International Study to Evaluate Recombinant Interleukin-2 in HIV Positive Patients Taking Anti-retroviral Therapy (ESPRIT)

Clinical Trial ID NCT00004978

PubWeight™ 14.22^‹?›

🔗 Visit the ClinicalTrials.gov page for NCT00004978

Top papers

Rank	Title	Journal	Year	PubWeight™‹?›
1	Effect of interleukin-2 on the pool of latently infected, resting CD4+ T cells in HIV-1-infected patients receiving highly active anti-retroviral therapy.	Nat Med	1999	4.81
2	Interleukin-2 therapy in patients with HIV infection.	N Engl J Med	2009	4.38
3	HIV infection induces changes in CD4+ T-cell phenotype and depletions within the CD4+ T-cell repertoire that are not immediately restored by antiviral or immune-based therapies.	Nat Med	1997	3.40
4	The evaluation of subcutaneous proleukin (interleukin-2) in a randomized international trial: rationale, design, and methods of ESPRIT.	Control Clin Trials	2002	1.73
5	Severity of cardiovascular disease outcomes among patients with HIV is related to markers of inflammation and coagulation.	J Am Heart Assoc	2014	1.26
6	Hepatitis B and C co-infection are independent predictors of progressive kidney disease in HIV-positive, antiretroviral-treated adults.	PLoS One	2012	1.16
7	Lessons learned: Infrastructure development and financial management for large, publicly funded, international trials.	Clin Trials	2016	1.06
8	Factors Associated With Plasma IL-6 Levels During HIV Infection.	J Infect Dis	2015	0.95
9	Relevance of Interleukin-6 and D-Dimer for Serious Non-AIDS Morbidity and Death among HIV-Positive Adults on Suppressive Antiretroviral Therapy.	PLoS One	2016	0.89
10	Factors associated with D-dimer levels in HIV-infected individuals.	PLoS One	2014	0.84
11	Interleukin 6 Is a Stronger Predictor of Clinical Events Than High-Sensitivity C-Reactive Protein or D-Dimer During HIV Infection.	J Infect Dis	2016	0.82
12	Circulating microRNAs in Sera Correlate with Soluble Biomarkers of Immune Activation but Do Not Predict Mortality in ART Treated Individuals with HIV-1 Infection: A Case Control Study.	PLoS One	2015	0.75
13	Predictors of bacterial pneumonia in Evaluation of Subcutaneous Interleukin-2 in a Randomized International Trial (ESPRIT).	HIV Med	2010	0.75