Observational Study on Anti-Tat Immune Response in HIV-1-infected HAART-treated Adult Subjects (ISS OBS T-002)

Clinical Trial ID NCT01024556

PubWeight™ 5.59‹?›

🔗 Visit the ClinicalTrials.gov page for NCT01024556

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Trans-activator gene of human T-lymphotropic virus type III (HTLV-III). Science 1985 12.75
2 Tat protein of HIV-1 stimulates growth of cells derived from Kaposi's sarcoma lesions of AIDS patients. Nature 1990 4.47
3 Release, uptake, and effects of extracellular human immunodeficiency virus type 1 Tat protein on cell growth and viral transactivation. J Virol 1993 3.68
4 An inhibitor of HIV-1 protease modulates proteasome activity, antigen presentation, and T cell responses. Proc Natl Acad Sci U S A 1998 1.50
5 Therapeutic immunization with HIV-1 Tat reduces immune activation and loss of regulatory T-cells and improves immune function in subjects on HAART. PLoS One 2010 1.13
6 Candidate HIV-1 Tat vaccine development: from basic science to clinical trials. AIDS 2006 1.12
7 Challenges in HIV Vaccine Research for Treatment and Prevention. Front Immunol 2014 0.93
8 The presence of anti-Tat antibodies in HIV-infected individuals is associated with containment of CD4+ T-cell decay and viral load, and with delay of disease progression: results of a 3-year cohort study. Retrovirology 2014 0.92
9 HIV-1 tat promotes integrin-mediated HIV transmission to dendritic cells by binding Env spikes and competes neutralization by anti-HIV antibodies. PLoS One 2012 0.91
10 HIV-1 Tat immunization restores immune homeostasis and attacks the HAART-resistant blood HIV DNA: results of a randomized phase II exploratory clinical trial. Retrovirology 2015 0.89
11 Development of a novel AIDS vaccine: the HIV-1 transactivator of transcription protein vaccine. Expert Opin Biol Ther 2015 0.79
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