Exploratory Study of XL765 (SAR245409) or XL147 (SAR245408) in Subjects With Recurrent Glioblastoma Who Are Candidates for Surgical Resection

Clinical Trial ID NCT01240460

PubWeight™ 8.23‹?›

🔗 Visit the ClinicalTrials.gov page for NCT01240460

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascade inhibitors: how mutations can result in therapy resistance and how to overcome resistance. Oncotarget 2012 1.96
2 Current clinical development of PI3K pathway inhibitors in glioblastoma. Neuro Oncol 2012 1.33
3 PI3K/Akt/mTOR signaling pathway and targeted therapy for glioblastoma. Oncotarget 2016 1.02
4 Unique biology of gliomas: challenges and opportunities. Trends Neurosci 2012 0.87
5 The mTOR signaling pathway as a treatment target for intracranial neoplasms. Neuro Oncol 2014 0.84
6 Molecular pathways: PI3K pathway phosphatases as biomarkers for cancer prognosis and therapy. Clin Cancer Res 2014 0.83
7 Seizures and gliomas - towards a single therapeutic approach. Nat Rev Neurol 2016 0.83
8 Phase I dose-escalation study of the PI3K/mTOR inhibitor voxtalisib (SAR245409, XL765) plus temozolomide with or without radiotherapy in patients with high-grade glioma. Neuro Oncol 2015 0.75
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