REVEAL: Randomized EValuation of the Effects of Anacetrapib Through Lipid-modification (REVEAL)

Clinical Trial ID NCT01252953

PubWeight™ 36.08‹?›

🔗 Visit the ClinicalTrials.gov page for NCT01252953

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Lipoprotein(a) concentrations, rosuvastatin therapy, and residual vascular risk: an analysis from the JUPITER Trial (Justification for the Use of Statins in Prevention: an Intervention Trial Evaluating Rosuvastatin). Circulation 2013 3.02
2 Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients. BMJ 2014 2.69
3 Statin-associated muscle symptoms: impact on statin therapy-European Atherosclerosis Society Consensus Panel Statement on Assessment, Aetiology and Management. Eur Heart J 2015 1.92
4 Novel HDL-directed pharmacotherapeutic strategies. Nat Rev Cardiol 2011 1.91
5 Cholesteryl ester transfer protein inhibition as a strategy to reduce cardiovascular risk. J Lipid Res 2012 1.46
6 Effects of Anacetrapib in Patients with Atherosclerotic Vascular Disease. N Engl J Med 2017 1.44
7 Residual macrovascular risk in 2013: what have we learned? Cardiovasc Diabetol 2014 1.20
8 Changes in lipoprotein subfraction concentration and composition in healthy individuals treated with the CETP inhibitor anacetrapib. J Lipid Res 2011 1.18
9 Rationale for cholesteryl ester transfer protein inhibition. Curr Opin Lipidol 2012 1.15
10 Dysfunctional HDL and atherosclerotic cardiovascular disease. Nat Rev Cardiol 2015 1.11
11 Lipids, blood pressure and kidney update 2015. Lipids Health Dis 2015 1.00
12 Increasing high-density lipoprotein cholesterol by cholesteryl ester transfer protein-inhibition: a rocky road and lessons learned? The early demise of the dal-HEART programme. Eur Heart J 2012 0.95
13 Current guidelines for high-density lipoprotein cholesterol in therapy and future directions. Vasc Health Risk Manag 2014 0.92
14 Future of cholesteryl ester transfer protein (CETP) inhibitors: a pharmacological perspective. Clin Pharmacokinet 2013 0.89
15 Measurement of LDL-C after treatment with the CETP inhibitor anacetrapib. J Lipid Res 2012 0.88
16 HDL, Atherosclerosis, and Emerging Therapies. Cholesterol 2013 0.87
17 Mechanistic systems modeling to guide drug discovery and development. Drug Discov Today 2012 0.86
18 HDL cholesterol is not HDL--don't judge the book by its cover. Nat Rev Cardiol 2012 0.85
19 HDL and cognition in neurodegenerative disorders. Neurobiol Dis 2014 0.84
20 Nonstatin Low-Density Lipoprotein-Lowering Therapy and Cardiovascular Risk Reduction-Statement From ATVB Council. Arterioscler Thromb Vasc Biol 2015 0.83
21 Mipomersen and other therapies for the treatment of severe familial hypercholesterolemia. Vasc Health Risk Manag 2012 0.82
22 High density lipoprotein and cardiovascular diseases. World J Cardiol 2013 0.81
23 CETP inhibitors and cardiovascular disease: Time to think again. F1000Res 2014 0.81
24 Hypertriglyceridemia and Cardiovascular Diseases: Revisited. Korean Circ J 2016 0.80
25 Pharmacotherapies for lipid modification: beyond the statins. Nat Rev Cardiol 2013 0.80
26 Patient considerations and clinical impact of cholesteryl ester transfer protein inhibitors in the management of dyslipidemia: focus on anacetrapib. Vasc Health Risk Manag 2012 0.78
27 New Era of Lipid-Lowering Drugs. Pharmacol Rev 2016 0.77
28 Changes in LDL particle concentrations after treatment with the cholesteryl ester transfer protein inhibitor anacetrapib alone or in combination with atorvastatin. J Clin Lipidol 2014 0.77
29 CETP Inhibition: Past Failures and Future Hopes. Clin Med Insights Cardiol 2016 0.76
30 Harnessing publicly available genetic data to prioritize lipid modifying therapeutic targets for prevention of coronary heart disease based on dysglycemic risk. Hum Genet 2016 0.75
31 Lipoprotein apheresis for the treatment of elevated circulating levels of lipoprotein(a): a critical literature review. Blood Transfus 2015 0.75
32 Treatment of dyslipidemia. F1000Prime Rep 2014 0.75
33 Reduction in PCSK9 levels induced by anacetrapib: an off-target effect? J Lipid Res 2015 0.75
34 Monogenic causes of elevated HDL cholesterol and implications for development of new therapeutics. Clin Lipidol 2013 0.75
35 Pharmacokinetics, pharmacodynamics and safety of CKD-519, a CETP inhibitor, in healthy subjects. Drug Des Devel Ther 2016 0.75
36 Single nucleotide polymorphisms in cholesteryl ester transfer protein gene and recurrent coronary heart disease or mortality in patients with established atherosclerosis. Am J Cardiol 2013 0.75
37 Randomized Evaluation of the Effects of Anacetrapib through Lipid-modification (REVEAL)-A large-scale, randomized, placebo-controlled trial of the clinical effects of anacetrapib among people with established vascular disease: Trial design, recruitment, and baseline characteristics. Am Heart J 2017 0.75
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