Study of VX-661 Alone and in Combination With Ivacaftor in Subjects Homozygous or Heterozygous to the F508del-Cystic Fibrosis Transmembrane Conductance Regulator(CFTR) Mutation

Clinical Trial ID NCT01531673

PubWeight™ 6.45‹?›

🔗 Visit the ClinicalTrials.gov page for NCT01531673

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Some gating potentiators, including VX-770, diminish ΔF508-CFTR functional expression. Sci Transl Med 2014 1.64
2 State of progress in treating cystic fibrosis respiratory disease. BMC Med 2012 0.96
3 Development, clinical utility, and place of ivacaftor in the treatment of cystic fibrosis. Drug Des Devel Ther 2013 0.87
4 CFTR Modulators for the Treatment of Cystic Fibrosis. P T 2014 0.81
5 On the mechanism of gating defects caused by the R117H mutation in cystic fibrosis transmembrane conductance regulator. J Physiol 2016 0.79
6 Interaction non grata between CFTR's correctors and potentiators. Ann Transl Med 2015 0.76
7 CFTR Modulators: Shedding Light on Precision Medicine for Cystic Fibrosis. Front Pharmacol 2016 0.75
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