Molecular Epidemiology of Lung Adenocarcinoma in Multi-ethnic Asian Phenotype

Clinical Trial ID NCT01774526

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Top papers

Rank Title Journal Year PubWeight™‹?›
1 Erlotinib in previously treated non-small-cell lung cancer. N Engl J Med 2005 31.48
2 Cancer statistics, 2005. CA Cancer J Clin 2005 25.65
3 Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers. J Natl Cancer Inst 2005 13.00
4 Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer: a randomized trial. JAMA 2003 12.35
5 Mutations in the epidermal growth factor receptor and in KRAS are predictive and prognostic indicators in patients with non-small-cell lung cancer treated with chemotherapy alone and in combination with erlotinib. J Clin Oncol 2005 9.95
6 Somatic mutations of the HER2 kinase domain in lung adenocarcinomas. Cancer Res 2005 4.25
7 Outcomes for elderly, advanced-stage non small-cell lung cancer patients treated with bevacizumab in combination with carboplatin and paclitaxel: analysis of Eastern Cooperative Oncology Group Trial 4599. J Clin Oncol 2008 3.83
8 Never-smokers with lung cancer: epidemiologic evidence of a distinct disease entity. J Clin Oncol 2006 2.86
9 EGFR-T790M is a rare lung cancer susceptibility allele with enhanced kinase activity. Cancer Res 2007 1.91
10 Dual MET-EGFR combinatorial inhibition against T790M-EGFR-mediated erlotinib-resistant lung cancer. Br J Cancer 2008 1.83
11 Reversed mutation rates of KRAS and EGFR genes in adenocarcinoma of the lung in Taiwan and their implications. Cancer 2008 1.16
12 EGFR point mutation in non-small cell lung cancer is occasionally accompanied by a second mutation or amplification. Cancer Sci 2006 1.04
13 Current management of advanced non-small cell lung cancer: targeted therapy. Semin Oncol 2005 1.00
14 Targeted therapy in advanced non-small-cell lung cancer. Semin Respir Crit Care Med 2008 0.82
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