| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Postoperative ileus: a preventable event.
|
Br J Surg
|
2000
|
3.67
|
|
2
|
Opioid-induced bowel dysfunction: pathophysiology and potential new therapies.
|
Drugs
|
2003
|
2.42
|
|
3
|
Review of postoperative ileus.
|
Am J Surg
|
2001
|
1.71
|
|
4
|
Alvimopan, a novel, peripherally acting mu opioid antagonist: results of a multicenter, randomized, double-blind, placebo-controlled, phase III trial of major abdominal surgery and postoperative ileus.
|
Ann Surg
|
2004
|
1.56
|
|
5
|
The opioid system in the gastrointestinal tract.
|
Neurogastroenterol Motil
|
2004
|
1.55
|
|
6
|
Postoperative ileus: etiologies and interventions.
|
Clin Gastroenterol Hepatol
|
2003
|
1.54
|
|
7
|
Phase III trial of alvimopan, a novel, peripherally acting, mu opioid antagonist, for postoperative ileus after major abdominal surgery.
|
Dis Colon Rectum
|
2005
|
1.50
|
|
8
|
Alvimopan, a peripherally acting mu-opioid receptor antagonist, compared with placebo in postoperative ileus after major abdominal surgery: results of a randomized, double-blind, controlled study.
|
Surg Endosc
|
2005
|
1.40
|
|
9
|
Opioids and opioid receptors in the enteric nervous system: from a problem in opioid analgesia to a possible new prokinetic therapy in humans.
|
Neurosci Lett
|
2004
|
1.30
|
|
10
|
Clinical trial: alvimopan for the management of post-operative ileus after abdominal surgery: results of an international randomized, double-blind, multicentre, placebo-controlled clinical study.
|
Aliment Pharmacol Ther
|
2008
|
1.17
|
|
11
|
Discovery of a potent, peripherally selective trans-3,4-dimethyl-4-(3-hydroxyphenyl)piperidine opioid antagonist for the treatment of gastrointestinal motility disorders.
|
J Med Chem
|
1994
|
1.17
|
|
12
|
Pathogenesis and clinical and economic consequences of postoperative ileus.
|
Am J Health Syst Pharm
|
2007
|
1.04
|
|
13
|
Patterns of gastrointestinal recovery after bowel resection and total abdominal hysterectomy: pooled results from the placebo arms of alvimopan phase III North American clinical trials.
|
J Am Coll Surg
|
2007
|
1.03
|
|
14
|
ADL 8-2698, a trans-3,4-dimethyl-4-(3-hydroxyphenyl) piperidine, prevents gastrointestinal effects of intravenous morphine without affecting analgesia.
|
Clin Pharmacol Ther
|
2001
|
0.96
|
|
15
|
Alvimopan for the management of postoperative ileus.
|
Ann Pharmacother
|
2005
|
0.84
|