Efficacy of H2 Receptor Antagonist in Prevention of Thienopyridine-related Peptic Ulcer

Clinical Trial ID NCT02418312

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Top papers

Rank Title Journal Year PubWeight™‹?›
1 Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation. N Engl J Med 2001 20.20
2 Clopidogrel and aspirin versus aspirin alone for the prevention of atherothrombotic events. N Engl J Med 2006 18.25
3 A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE). CAPRIE Steering Committee. Lancet 1996 16.32
4 Effects of pretreatment with clopidogrel and aspirin followed by long-term therapy in patients undergoing percutaneous coronary intervention: the PCI-CURE study. Lancet 2001 8.54
5 Genetic determinants of response to clopidogrel and cardiovascular events. N Engl J Med 2008 8.39
6 Risk of adverse outcomes associated with concomitant use of clopidogrel and proton pump inhibitors following acute coronary syndrome. JAMA 2009 7.78
7 Clopidogrel versus aspirin and esomeprazole to prevent recurrent ulcer bleeding. N Engl J Med 2005 6.39
8 A population-based study of the drug interaction between proton pump inhibitors and clopidogrel. CMAJ 2009 6.21
9 Influence of omeprazole on the antiplatelet action of clopidogrel associated with aspirin: the randomized, double-blind OCLA (Omeprazole CLopidogrel Aspirin) study. J Am Coll Cardiol 2008 5.77
10 Famotidine for the prevention of gastric and duodenal ulcers caused by nonsteroidal antiinflammatory drugs. N Engl J Med 1996 2.37
11 Famotidine for the prevention of peptic ulcers and oesophagitis in patients taking low-dose aspirin (FAMOUS): a phase III, randomised, double-blind, placebo-controlled trial. Lancet 2009 2.06
12 Famotidine is inferior to pantoprazole in preventing recurrence of aspirin-related peptic ulcers or erosions. Gastroenterology 2009 1.80
13 Esomeprazole with clopidogrel reduces peptic ulcer recurrence, compared with clopidogrel alone, in patients with atherosclerosis. Gastroenterology 2010 1.62
14 Famotidine for healing and maintenance in nonsteroidal anti-inflammatory drug-associated gastroduodenal ulceration. Gastroenterology 1997 1.59
15 Platelets modulate gastric ulcer healing: role of endostatin and vascular endothelial growth factor release. Proc Natl Acad Sci U S A 2001 1.39
16 Clopidogrel: a review of its mechanism of action. Platelets 1998 1.05
17 Proton pump inhibitor and clopidogrel interaction: fact or fiction? Am J Gastroenterol 2009 0.97
18 Gastroduodenal tolerance of 75 mg clopidogrel versus 325 mg aspirin in healthy volunteers. A gastroscopic study. Scand J Gastroenterol 2000 0.92
19 Neutrophils, Helicobacter pylori, and nonsteroidal anti-inflammatory drug ulcers. Gastroenterology 1999 0.89
20 High-dose versus low-dose esomeprazole-based triple therapy for Helicobacter pylori infection. Eur J Clin Invest 2007 0.88
21 High incidence of clopidogrel-associated gastrointestinal bleeding in patients with previous peptic ulcer disease. Aliment Pharmacol Ther 2003 0.87
22 P2Y receptor antagonists in thrombosis. Curr Opin Investig Drugs 2005 0.84
23 Risk of combining PPIs with thienopyridines: fact or fiction? Lancet 2009 0.77
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