Safety of Topical Tranexamic Acid in Total Joint Arthroplasty in High Risk Patients

Clinical Trial ID NCT02644473

Rank	Title	Journal	Year	PubWeight™‹?›
1	Topical application of tranexamic acid reduces postoperative blood loss in total knee arthroplasty: a randomized, controlled trial.	J Bone Joint Surg Am	2010	2.89
2	Use of tranexamic acid for an effective blood conservation strategy after total knee arthroplasty.	Br J Anaesth	1999	1.49
3	Tranexamic acid: a review of its use in the treatment of hyperfibrinolysis.	Drugs	2012	1.46
4	The effect of tranexamic acid on blood loss and use of blood products in total knee arthroplasty: a meta-analysis.	Knee Surg Sports Traumatol Arthrosc	2011	1.26
5	Combination of intravenous and topical application of tranexamic acid in primary total knee arthroplasty: a prospective randomized controlled trial.	J Arthroplasty	2014	1.03
6	Topical (intra-articular) tranexamic acid reduces blood loss and transfusion rates following total hip replacement: a randomized controlled trial (TRANX-H).	J Bone Joint Surg Am	2013	1.01
7	Preliminary results suggest tranexamic acid is safe and effective in arthroplasty patients with severe comorbidities.	Clin Orthop Relat Res	2014	0.87
8	Venous thromboembolism and mortality associated with tranexamic acid use during total hip and knee arthroplasty.	J Arthroplasty	2014	0.86