| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Acute opioid tolerance: intraoperative remifentanil increases postoperative pain and morphine requirement.
|
Anesthesiology
|
2000
|
2.48
|
|
2
|
Alvimopan, a novel, peripherally acting mu opioid antagonist: results of a multicenter, randomized, double-blind, placebo-controlled, phase III trial of major abdominal surgery and postoperative ileus.
|
Ann Surg
|
2004
|
1.56
|
|
3
|
Intraoperative remifentanil infusion does not increase postoperative opioid consumption compared with 70% nitrous oxide.
|
Anesthesiology
|
2005
|
1.55
|
|
4
|
Phase III trial of alvimopan, a novel, peripherally acting, mu opioid antagonist, for postoperative ileus after major abdominal surgery.
|
Dis Colon Rectum
|
2005
|
1.50
|
|
5
|
Gastrointestinal tract recovery in patients undergoing bowel resection: results of a randomized trial of alvimopan and placebo with a standardized accelerated postoperative care pathway.
|
Arch Surg
|
2008
|
1.43
|
|
6
|
Alvimopan, a peripherally acting mu-opioid receptor antagonist, compared with placebo in postoperative ileus after major abdominal surgery: results of a randomized, double-blind, controlled study.
|
Surg Endosc
|
2005
|
1.40
|
|
7
|
Postoperative wound infections complicating adult spine surgery.
|
J Spinal Disord
|
1992
|
1.30
|
|
8
|
No clinical evidence of acute opioid tolerance after remifentanil-based anaesthesia.
|
Br J Anaesth
|
2001
|
1.10
|
|
9
|
Development of acute opioid tolerance during infusion of remifentanil for pediatric scoliosis surgery.
|
Anesth Analg
|
2006
|
0.98
|
|
10
|
A double-blind, randomized, placebo-controlled phase III study of the safety of alvimopan in patients who undergo simple total abdominal hysterectomy.
|
Am J Obstet Gynecol
|
2006
|
0.97
|
|
11
|
Remifentanil infusion in association with fentanyl-propofol anaesthesia in patients undergoing cardiac surgery: effects on morphine requirement and postoperative analgesia.
|
Br J Anaesth
|
2005
|
0.95
|
|
12
|
The efficacy of intravenous 0.15 versus 0.25 mg/kg intraoperative morphine for immediate postoperative analgesia after remifentanil-based anesthesia for major surgery.
|
Anesth Analg
|
2000
|
0.93
|
|
13
|
Economic analysis of alvimopan in North American Phase III efficacy trials.
|
Am J Health Syst Pharm
|
2009
|
0.90
|