Exercise Dose and Metformin for Vascular Health in Adults With Metabolic Syndrome

Clinical Trial ID NCT03355469

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Top papers

Rank Title Journal Year PubWeight™‹?›
1 Prediction of cardiovascular events and all-cause mortality with arterial stiffness: a systematic review and meta-analysis. J Am Coll Cardiol 2010 9.44
2 Aortic pulse-wave velocity and its relationship to mortality in diabetes and glucose intolerance: an integrated index of vascular function? Circulation 2002 6.22
3 Aerobic interval training versus continuous moderate exercise as a treatment for the metabolic syndrome: a pilot study. Circulation 2008 4.61
4 Aortic stiffness is an independent predictor of fatal stroke in essential hypertension. Stroke 2003 4.10
5 Predictive value of noninvasively determined endothelial dysfunction for long-term cardiovascular events in patients with peripheral vascular disease. J Am Coll Cardiol 2003 3.87
6 Cardiovascular outcomes in trials of oral diabetes medications: a systematic review. Arch Intern Med 2008 3.54
7 Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute scientific statement: Executive Summary. Crit Pathw Cardiol 2005 2.31
8 Comparison of aerobic versus resistance exercise training effects on metabolic syndrome (from the Studies of a Targeted Risk Reduction Intervention Through Defined Exercise - STRRIDE-AT/RT). Am J Cardiol 2011 2.28
9 Obesity blunts insulin-mediated microvascular recruitment in human forearm muscle. Diabetes 2006 2.14
10 Improved endothelial function with metformin in type 2 diabetes mellitus. J Am Coll Cardiol 2001 2.10
11 Assessment and treatment of cardiovascular risk in prediabetes: impaired glucose tolerance and impaired fasting glucose. Am J Cardiol 2011 1.82
12 Microvascular function predicts cardiovascular events in primary prevention: long-term results from the Firefighters and Their Endothelium (FATE) study. Circulation 2011 1.58
13 Mixed meal and light exercise each recruit muscle capillaries in healthy humans. Am J Physiol Endocrinol Metab 2006 1.52
14 Insulin regulates its own delivery to skeletal muscle by feed-forward actions on the vasculature. Am J Physiol Endocrinol Metab 2011 1.48
15 Impact of Metformin on Exercise-Induced Metabolic Adaptations to Lower Type 2 Diabetes Risk. Exerc Sport Sci Rev 2016 1.45
16 Independent and combined effects of exercise training and metformin on insulin sensitivity in individuals with prediabetes. Diabetes Care 2011 1.38
17 Prolonged reactive oxygen species generation and nuclear factor-kappaB activation after a high-fat, high-carbohydrate meal in the obese. J Clin Endocrinol Metab 2007 1.38
18 Infusing lipid raises plasma free fatty acids and induces insulin resistance in muscle microvasculature. J Clin Endocrinol Metab 2009 1.30
19 Free fatty acids induce insulin resistance in both cardiac and skeletal muscle microvasculature in humans. J Clin Endocrinol Metab 2010 1.16
20 Obesity blunts microvascular recruitment in human forearm muscle after a mixed meal. Diabetes Care 2009 1.15
21 Metformin improves endothelial function in patients with metabolic syndrome. J Intern Med 2005 1.05
22 Aerobic exercise training reduces arterial stiffness in metabolic syndrome. J Appl Physiol (1985) 2014 0.91
23 Metformin modifies the exercise training effects on risk factors for cardiovascular disease in impaired glucose tolerant adults. Obesity (Silver Spring) 2013 0.89
24 Exercise training with weight loss and either a high- or low-glycemic index diet reduces metabolic syndrome severity in older adults. Ann Nutr Metab 2012 0.88
25 Resistance exercise and aerobic exercise when paired with dietary energy restriction both reduce the clinical components of metabolic syndrome in previously physically inactive males. Eur J Appl Physiol 2011 0.88
26 Exercise interventions and peripheral arterial function: implications for cardio-metabolic disease. Prog Cardiovasc Dis 2014 0.87
27 Exercise training and artery function in humans: nonresponse and its relationship to cardiovascular risk factors. J Appl Physiol (1985) 2014 0.84
28 Predictors of improvement in endothelial function after exercise training in a diverse sample of postmenopausal women. J Womens Health (Larchmt) 2013 0.82
29 Regular aerobic exercise, without weight loss, improves endothelium-dependent vasodilation in overweight and obese adults. Obesity (Silver Spring) 2010 0.81
30 Early microvascular recruitment modulates subsequent insulin-mediated skeletal muscle glucose metabolism during lipid infusion. Diabetes Care 2012 0.78
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