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Early Phase Administration of Anakinra as a Rescue Treatment for Inhaled Allergen Challenge-Induced Airway Inflammation (EarlyAna)
Clinical Trial ID NCT03513471
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🔗 Visit the ClinicalTrials.gov page for NCT03513471
Top papers
Rank
Title
Journal
Year
PubWeight™
‹?›
1
The interleukin-1 family: back to the future.
Immunity
2013
3.90
2
Economic burden of asthma: a systematic review.
BMC Pulm Med
2009
3.10
3
Risk of infectious complications in patients taking glucocorticosteroids.
Rev Infect Dis
1990
2.42
4
National surveillance of asthma: United States, 2001-2010.
Vital Health Stat 3
2012
2.18
5
IL-1 receptor antagonist reduces endotoxin-induced airway inflammation in healthy volunteers.
J Allergy Clin Immunol
2014
2.17
6
Asthma exacerbations: origin, effect, and prevention.
J Allergy Clin Immunol
2011
2.09
7
Controlled trial of oral prednisone in the emergency department treatment of children with acute asthma.
Pediatrics
1993
1.80
8
The intratracheal administration of endotoxin and cytokines. III. The interleukin-1 (IL-1) receptor antagonist inhibits endotoxin- and IL-1-induced acute inflammation.
Am J Pathol
1991
1.58
9
Experimental rhinovirus 16 infection. Effects on cell differentials and soluble markers in sputum in asthmatic subjects.
Am J Respir Crit Care Med
1997
1.55
10
Glucocorticoids in acute asthma. A critical controlled trial.
Am J Med
1983
1.46
11
Rhinovirus infection of allergen-sensitized and -challenged mice induces eotaxin release from functionally polarized macrophages.
J Immunol
2010
1.37
12
The polymeric mucin Muc5ac is required for allergic airway hyperreactivity.
Nat Commun
2015
1.09
13
Effect of interleukin-1 beta on airway hyperresponsiveness and inflammation in sensitized and nonsensitized Brown-Norway rats.
J Allergy Clin Immunol
1994
1.06
14
Airway inflammation and illness severity in response to experimental rhinovirus infection in asthma.
Chest
2014
1.00
15
Potential role of interleukin-1 in allergen-induced late asthmatic reactions in guinea pigs: suppressive effect of interleukin-1 receptor antagonist on late asthmatic reaction.
J Allergy Clin Immunol
1995
0.98
16
Adenovirus expressing interleukin-1 receptor antagonist alleviates allergic airway inflammation in a murine model of asthma.
Gene Ther
2006
0.94
17
Local IL-17A potentiates early neutrophil recruitment to the respiratory tract during severe RSV infection.
PLoS One
2013
0.91
18
Childhood asthma hospitalizations in the United States, 2000-2009.
J Pediatr
2013
0.88
19
IL-1β induction of MUC5AC gene expression is mediated by CREB and NF-κB and repressed by dexamethasone.
Am J Physiol Lung Cell Mol Physiol
2014
0.86
20
Delayed resolution of lung inflammation in Il-1rn-/- mice reflects elevated IL-17A/granulocyte colony-stimulating factor expression.
Am J Respir Cell Mol Biol
2012
0.85
21
Interleukin-1beta-induced hyperresponsiveness to [Sar9,Met(O2)11]substance P in isolated human bronchi.
Eur J Pharmacol
1999
0.81
22
Asthma: Hospitalization Trends and Predictors of In-Hospital Mortality and Hospitalization Costs in the USA (2001-2010).
Int Arch Allergy Immunol
2015
0.78
23
The acute effects of corticosteroids in bronchial asthma.
Eur J Respir Dis Suppl
1982
0.75
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