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Management of Newly Diagnosed and Uncontrolled Hypertension With Fixed-Dose Combination of Perindopril/Amlodipine and Perindopril/Indapamide/Amlodipine (PRECIOUS)

Clinical Trial ID NCT03738761

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🔗 Visit the ClinicalTrials.gov page for NCT03738761

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Treatment of hypertension in patients 80 years of age or older. N Engl J Med 2008 21.04
2 2013 ESH/ESC Guidelines for the management of arterial hypertension: the Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). J Hypertens 2013 18.17
3 Randomised trial of a perindopril-based blood-pressure-lowering regimen among 6,105 individuals with previous stroke or transient ischaemic attack. Lancet 2001 17.97
4 Effects of a fixed combination of perindopril and indapamide on macrovascular and microvascular outcomes in patients with type 2 diabetes mellitus (the ADVANCE trial): a randomised controlled trial. Lancet 2007 14.96
5 Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol adding bendroflumethiazide as required, in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA): a multicentre randomised controlled trial. Lancet 2005 12.92
6 2003 World Health Organization (WHO)/International Society of Hypertension (ISH) statement on management of hypertension. J Hypertens 2003 12.49
7 Efficacy of perindopril in reduction of cardiovascular events among patients with stable coronary artery disease: randomised, double-blind, placebo-controlled, multicentre trial (the EUROPA study). Lancet 2003 9.88
8 Treatment of Mild Hypertension Study. Final results. Treatment of Mild Hypertension Study Research Group. JAMA 1993 6.27
9 Rationale and design for the Antihypertensive and Lipid Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). ALLHAT Research Group. Am J Hypertens 1996 4.66
10 Amlodipine. A reappraisal of its pharmacological properties and therapeutic use in cardiovascular disease. Drugs 1995 1.09
11 The safety of amlodipine. Am Heart J 1989 1.02
12 Differences in first dose response to angiotensin converting enzyme inhibition in congestive heart failure: a placebo controlled study. Br Heart J 1991 1.00
13 Effect of low-dose perindopril/indapamide on albuminuria in diabetes: preterax in albuminuria regression: PREMIER. Hypertension 2003 0.98
14 Comparison of different therapeutic strategies in hypertension: a low-dose combination of perindopril/indapamide versus a sequential monotherapy or a stepped-care approach. J Hypertens 2004 0.96
15 Valsartan, a new angiotensin II antagonist for the treatment of essential hypertension: a comparative study of the efficacy and safety against amlodipine. Clin Pharmacol Ther 1996 0.92
16 Multicenter dose-response study of the effect of indapamide in the treatment of patients with mild to moderate hypertension. Clin Ther 1983 0.92
17 Perindopril. A review of its pharmacokinetics and clinical pharmacology. Drugs 1990 0.91
18 Perindopril/indapamide combination more effective than enalapril in reducing blood pressure and left ventricular mass: the PICXEL study. J Hypertens 2005 0.90
19 Perindopril: an updated review of its use in hypertension. Drugs 2001 0.89
20 Efficacy, tolerability, and effects on quality of life of losartan, alone or with hydrochlorothiazide, versus amlodipine, alone or with hydrochlorothiazide, in patients with essential hypertension. Clin Ther 1997 0.88
21 Clinical experience with perindopril in African-American hypertensive patients: a large United States community trial. Am J Hypertens 2004 0.85
22 Antihypertensive utility of perindopril in a large, general practice-based clinical trial. J Clin Hypertens (Greenwich) 2004 0.84
23 The classification of calcium antagonists and their selection in the treatment of hypertension. A reappraisal. Drugs 1998 0.84
24 Indapamide. A review of its pharmacodynamic properties and therapeutic efficacy in hypertension. Drugs 1984 0.84
25 Rational pharmacotherapy of hypertension in the elderly: analysis of the choice and dosage of drugs. J Clin Pharm Ther 2001 0.82
26 Perindopril postmarketing surveillance: a 12 month study in 47,351 hypertensive patients. Br J Clin Pharmacol 1998 0.81
27 Clinical experience with perindopril in patients nonresponsive to previous antihypertensive therapy: a large US community trial. Am J Ther 2004 0.80
28 Angiotensin-converting enzyme inhibition in cardiovascular disease: evidence with perindopril. Expert Rev Cardiovasc Ther 2005 0.80
29 Differences between amlodipine and lisinopril in control of clinic and twenty-four hour ambulatory blood pressures. J Hum Hypertens 1998 0.79
30 Fixed-dose combinations as initial therapy for hypertension: a review of approved agents and a guide to patient selection. Drugs 2009 0.78
31 Long-term acceptability of perindopril: European multicenter trial on 856 patients. Am J Med 1992 0.78
32 Comparative effects of felodipine ER, amlodipine and nifedipine GITS on 24 h blood pressure control and trough to peak ratios in mild to moderate ambulatory hypertension: a forced titration study. Can J Cardiol 1998 0.77
33 Analysis of well-being and 24-hour blood pressure recording in a comparative study between indapamide and captopril. Am J Med 1988 0.76
34 Double-blind, randomized, multicentre comparison of the effects of amlodipine and perindopril on 24 h therapeutic coverage and beyond in patients with mild to moderate hypertension. General Physicians Investigators' Group. J Hypertens 1999 0.76
35 A comparison of indapamide SR 1.5 mg with both amlodipine 5 mg and hydrochlorothiazide 25 mg in elderly hypertensive patients: a randomized double-blind controlled study. J Hypertens 2001 0.76
36 The role of fixed-dose combination therapy with drugs that target the renin-angiotensin system in the hypertension paradigm. Clin Exp Hypertens 2010 0.76
37 Relative efficacy and tolerability of lacidipine and amlodipine in patients with mild-to-moderate hypertension: a randomized double-blind study. J Cardiovasc Pharmacol 1996 0.76
38 Perindopril treatment for congestive heart failure. Am J Cardiol 2001 0.75
39 Antihypertensive efficacy and acceptability of perindopril in elderly hypertensive patients. Am J Cardiol 1993 0.75
40 Perindopril. Heart Dis 2001 0.75
41 Effect of perindopril on 24-hour blood pressure levels and hemodynamic responses to physical and mental stress in elderly hypertensive patients. Clin Ther 1995 0.75
42 Clinical implications of indapamide sustained release 1.5 mg in hypertension. Clin Pharmacokinet 1999 0.75
43 Comparison of the antihypertensive effects of indapamide and metoprolol. Postgrad Med J 1981 0.75
44 Indapamide and atenolol in the treatment of hypertension: double-blind comparative and combination study. Curr Med Res Opin 1983 0.75
45 Ambulatory blood pressure profiles in patients treated with once-daily diltiazem extended-release or indapamide alone or in combination. Am J Ther 2000 0.75
46 Clinical efficacy and safety of indapamide in essential hypertension. Am Heart J 1983 0.75
47 Perindopril/indapamide combination in the first-line treatment of hypertension and end-organ protection. Expert Rev Cardiovasc Ther 2006 0.75
48 International multicentre study of indapamide in the treatment of essential arterial hypertension. Postgrad Med J 1981 0.75
49 Indapamide in hypertension: results of a French multi-centre study in ambulant subjects. Curr Med Res Opin 1983 0.75
50 Amlodipine versus atenolol in essential hypertension. Am J Cardiol 1994 0.75
51 Antihypertensive efficacy of the ACE-inhibitor perindopril in the elderly. J Hum Hypertens 2000 0.75
52 Distinctive properties of perindopril among converting enzyme inhibitors in congestive heart failure. Can J Cardiol 1994 0.75
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