Sulfasalazine in Decreasing Opioids Requirements in Breast Cancer Patients

Clinical Trial ID NCT03847311

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Top papers

Rank Title Journal Year PubWeight™‹?›
1 Opioid therapy for chronic pain. N Engl J Med 2003 7.30
2 Biologic and pharmacologic regulation of mammalian glutathione synthesis. Free Radic Biol Med 1999 3.61
3 Opioid epidemic in the United States. Pain Physician 2012 3.40
4 Systematic review: treatment agreements and urine drug testing to reduce opioid misuse in patients with chronic pain. Ann Intern Med 2010 3.17
5 The x(c)- cystine/glutamate antiporter: a potential target for therapy of cancer and other diseases. J Cell Physiol 2008 3.05
6 Glutathione in cancer biology and therapy. Crit Rev Clin Lab Sci 2006 3.03
7 A comprehensive review of opioid-induced hyperalgesia. Pain Physician 2011 2.43
8 Regulation of μ-opioid receptors: desensitization, phosphorylation, internalization, and tolerance. Pharmacol Rev 2013 2.42
9 Sulfasalazine, a potent suppressor of lymphoma growth by inhibition of the x(c)- cystine transporter: a new action for an old drug. Leukemia 2001 2.03
10 Chronic morphine induces downregulation of spinal glutamate transporters: implications in morphine tolerance and abnormal pain sensitivity. J Neurosci 2002 1.78
11 Tonic descending facilitation from the rostral ventromedial medulla mediates opioid-induced abnormal pain and antinociceptive tolerance. J Neurosci 2001 1.76
12 Clinical pharmacokinetics of sulphasalazine, its metabolites and other prodrugs of 5-aminosalicylic acid. Clin Pharmacokinet 1985 1.41
13 Clinical experience of long-term treatment with epidural and intrathecal opioids--a nationwide survey. Acta Anaesthesiol Scand 1988 1.04
14 Opioid-induced hyperalgesia and tolerance. Am J Ther 2010 1.02
15 Gabapentin for the treatment of cancer-related pain syndromes. Rev Recent Clin Trials 2010 0.79
16 Pain and opioid addiction: what is the connection? Curr Pain Headache Rep 2010 0.77
17 A prospective open-label trial of gabapentin as an adjuvant analgesic with opioids for Japanese patients with neuropathic cancer pain. Int J Clin Oncol 2010 0.75
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