Focused Ultrasound and Exosomes to Treat Depression, Anxiety, and Dementias

Clinical Trial ID NCT04202770

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Top papers

Rank Title Journal Year PubWeight™‹?›
1 Comparative efficacy and acceptability of 12 new-generation antidepressants: a multiple-treatments meta-analysis. Lancet 2009 14.52
2 Acute and longer-term outcomes in depressed outpatients requiring one or several treatment steps: a STAR*D report. Am J Psychiatry 2006 12.41
3 Deep brain stimulation for treatment-resistant depression. Neuron 2005 12.39
4 Reciprocal limbic-cortical function and negative mood: converging PET findings in depression and normal sadness. Am J Psychiatry 1999 7.87
5 Limbic-cortical dysregulation: a proposed model of depression. J Neuropsychiatry Clin Neurosci 1997 6.75
6 Burden of depressive disorders by country, sex, age, and year: findings from the global burden of disease study 2010. PLoS Med 2013 6.04
7 Cingulate function in depression: a potential predictor of treatment response. Neuroreport 1997 4.48
8 Modulating dysfunctional limbic-cortical circuits in depression: towards development of brain-based algorithms for diagnosis and optimised treatment. Br Med Bull 2003 4.08
9 The subgenual anterior cingulate cortex in mood disorders. CNS Spectr 2008 3.40
10 Cerebrospinal fluid {beta}-amyloid 42 and tau proteins as biomarkers of Alzheimer-type pathologic changes in the brain. Arch Neurol 2009 3.34
11 Subcallosal cingulate gyrus deep brain stimulation for treatment-resistant depression. Biol Psychiatry 2008 3.00
12 Blood-brain barrier disruption induced by focused ultrasound and circulating preformed microbubbles appears to be characterized by the mechanical index. Ultrasound Med Biol 2008 2.17
13 Targeted electrode-based modulation of neural circuits for depression. J Clin Invest 2009 2.03
14 Nilotinib reverses loss of dopamine neurons and improves motor behavior via autophagic degradation of α-synuclein in Parkinson's disease models. Hum Mol Genet 2013 1.94
15 Volumetric reduction in left subgenual prefrontal cortex in early onset depression. Biol Psychiatry 2002 1.94
16 Defining the neural circuitry of depression: toward a new nosology with therapeutic implications. Biol Psychiatry 2007 1.39
17 Positron emission tomography imaging in depression: a neural systems perspective. Neuroimaging Clin N Am 2003 1.34
18 Antidepressant medications: a review of the evidence for drug-induced sexual dysfunction. J Affect Disord 2002 1.15
19 Modulating limbic-cortical circuits in depression: targets of antidepressant treatments. Semin Clin Neuropsychiatry 2002 0.92
20 Increased subgenual prefrontal cortex size in remitted patients with major depressive disorder. Psychiatry Res 2009 0.92
21 Magnetic resonance spectroscopy as a predictor of conversion of mild cognitive impairment to dementia. J Neurol Sci 2013 0.86
22 Depression, II: localization of pathophysiology. Am J Psychiatry 2002 0.83
23 Epidemiology of anxiety disorders in the 21st century. Dialogues Clin Neurosci 2015 0.80
24 Development of White Matter Microstructure and Intrinsic Functional Connectivity Between the Amygdala and Ventromedial Prefrontal Cortex: Associations With Anxiety and Depression. Biol Psychiatry 2017 0.76
25 Concise Review: Extracellular Vesicles Overcoming Limitations of Cell Therapies in Ischemic Stroke. Stem Cells Transl Med 2017 0.75
26 Mesenchymal Stem Cell therapy in Ischemic stroke: A meta-analysis of preclinical studies. Clin Pharmacol Ther 2017 0.75
27 Stem Cell Therapy for Abrogating Stroke-Induced Neuroinflammation and Relevant Secondary Cell Death Mechanisms. Prog Neurobiol 2017 0.75
28 A Focused Review of Clinical and Preclinical Studies of Cell-Based Therapies in Stroke. Neurosurgery 2017 0.75
29 Rev Neurol (Paris) 2017 0.75
30 Macrophage exosomes as natural nanocarriers for protein delivery to inflamed brain. Biomaterials 2017 0.75
31 A connectomic approach for subcallosal cingulate deep brain stimulation surgery: prospective targeting in treatment-resistant depression. Mol Psychiatry 2017 0.75
32 Mesenchymal Stem Cell Therapy for Ischemic Stroke. Acta Med Okayama 2017 0.75
33 Can anxiety damage the brain? Curr Opin Psychiatry 2016 0.75
34 Therapeutic Effects of Mesenchymal Stem Cell-Derived Exosomes in Cardiovascular Disease. Adv Exp Med Biol 2017 0.75
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