Recent patents on cardiovascular drug discovery (Recent Pat Cardiovasc Drug Discov)

Journal PubWeight™ 115.75‹?›

Top papers

Rank Title Year PubWeight™‹?›
1 Edaravone (3-methyl-1-phenyl-2-pyrazolin-5-one), a novel free radical scavenger, for treatment of cardiovascular diseases. 2006 1.35
2 Resveratrol: a therapeutic promise for cardiovascular diseases. 2007 1.24
3 MicroRNAs and ischemic heart disease: towards a better comprehension of pathogenesis, new diagnostic tools and new therapeutic targets. 2009 1.17
4 The vascular endothelin system in hypertension--recent patents and discoveries. 2006 1.16
5 Oxidative stress and endothelial function: therapeutic interventions. 2011 1.05
6 Methylglyoxal and advanced glycation endproducts: new therapeutic horizons? 2007 0.98
7 A review of Sirt1 and Sirt1 modulators in cardiovascular and metabolic diseases. 2008 0.98
8 Evaluation of clinical efficacy of fasudil for the treatment of pulmonary arterial hypertension. 2012 0.98
9 Specific antidotes in development for reversal of novel anticoagulants: a review. 2014 0.97
10 Fibroblast growth factors, fibroblast growth factor receptors, diseases, and drugs. 2006 0.97
11 Oxidative stress induced mitochondrial DNA deletion as a hallmark for the drug development in the context of the cerebrovascular diseases. 2011 0.96
12 New approaches in the diagnosis of atherosclerosis and treatment of cardiovascular disease. 2008 0.92
13 MicroRNA-21 as therapeutic target in cancer and cardiovascular disease. 2010 0.92
14 Gender differences in ischemic heart disease. 2009 0.91
15 Omega-3 fatty acids: from biochemistry to their clinical use in the prevention of cardiovascular disease. 2007 0.91
16 Rimonabant for the treatment of obesity. 2008 0.91
17 Ultrasound microbubble contrast and current clinical applications. 2011 0.90
18 Mitochondrially targeted antioxidants for the treatment of cardiovascular diseases. 2010 0.90
19 Oxidative stress in cardiovascular disease: a new avenue toward future therapeutic approaches. 2006 0.89
20 The role of angiotensin type 1 receptor in inflammation and endothelial dysfunction. 2007 0.89
21 Novel drugs and the response to hypoxia: HIF stabilizers and prolyl hydroxylase. 2006 0.88
22 Non-steroidal LXR agonists; an emerging therapeutic strategy for the treatment of atherosclerosis. 2006 0.88
23 Soluble epoxide hydrolase: a novel target for the treatment of hypertension. 2006 0.88
24 Bivalirudin: alternative anticoagulation during cardiopulmonary bypass in patients with heparin-induced thrombocytopenia. 2010 0.88
25 Methods for identifying cardiovascular agents: a review. 2006 0.88
26 Actual knowledge of systemic inflammation reaction during cardiopulmonary bypass. 2012 0.88
27 Levosimendan for heart-operated patients: what is the state of the art? 2009 0.88
28 Targets for the treatment of erectile dysfunction: is NO/cGMP still the answer? 2007 0.88
29 Novel molecular targets in the treatment of cardiac hypertrophy. 2006 0.88
30 Homocysteine and heart failure: an overview. 2009 0.88
31 Role of PPAR in cardiovascular diseases. 2006 0.88
32 Vorapaxar, a Protease-Activated Receptor-1 Antagonist, a Double -Edged Sword! 2015 0.87
33 The zebrafish as a novel tool for cardiovascular drug discovery. 2009 0.87
34 Endothelial dysfunction and atherosclerosis: focus on novel therapeutic approaches. 2012 0.87
35 Anti-atherosclerotic therapy based on botanicals. 2013 0.87
36 MMP inhibitors in cardiac diseases: an update. 2007 0.87
37 Effect of immunoglobulin therapy on blood viscosity and potential concerns of thromboembolism, especially in patients with acute Kawasaki disease. 2008 0.86
38 Novel pharmacologic strategies to protect the liver from ischemia-reperfusion injury. 2008 0.86
39 Cardiovascular effects of green tea catechins: progress and promise. 2012 0.86
40 Modulators of vascular sex hormone receptors and their effects in estrogen-deficiency states associated with menopause. 2008 0.85
41 Circulating microparticles as therapeutic targets in cardiovascular diseases. 2007 0.85
42 Pharmacologic treatment for prehypertension: to treat or not to treat? 2009 0.85
43 A review of cilostazol, a phosphodiesterase inhibitor, and its role in preventing both coronary and peripheral arterial restenosis following endovascular therapy. 2009 0.85
44 Ryanodine receptor: a novel therapeutic target in heart disease. 2007 0.85
45 TNNI3K could be a novel molecular target for the treatment of cardiac diseases. 2009 0.83
46 Statins as antihypertensives. 2008 0.83
47 The role of omega-3 polyunsaturated fatty acids supplementation in childhood: a review. 2013 0.82
48 Aldose reductase inhibition: emerging drug target for the treatment of cardiovascular complications. 2010 0.82
49 Interactive effect of combined exposure to active and passive smoking on cardiovascular system. 2011 0.82
50 Targeting MCP-1 to reduce vascular complications of obesity. 2009 0.82
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