|
1
|
Is anthelmintic resistance a concern for the control of human soil-transmitted helminths?
|
2011
|
1.35
|
|
2
|
Persistent detection of Plasmodium falciparum, P. malariae, P. ovale curtisi and P. ovale wallikeri after ACT treatment of asymptomatic Ghanaian school-children.
|
2013
|
1.31
|
|
3
|
Moxidectin and the avermectins: Consanguinity but not identity.
|
2012
|
1.25
|
|
4
|
Drug repurposing and human parasitic protozoan diseases.
|
2014
|
1.23
|
|
5
|
Visceral leishmaniasis treatment: What do we have, what do we need and how to deliver it?
|
2012
|
1.20
|
|
6
|
P-glycoproteins and other multidrug resistance transporters in the pharmacology of anthelmintics: Prospects for reversing transport-dependent anthelmintic resistance.
|
2011
|
1.20
|
|
7
|
Recent Developments in Sterol 14-demethylase Inhibitors for Chagas Disease.
|
2012
|
1.15
|
|
8
|
Artemisinin resistance in Plasmodium falciparum: A process linked to dormancy?
|
2012
|
1.14
|
|
9
|
Repurposing drugs for the treatment and control of helminth infections.
|
2014
|
1.08
|
|
10
|
The proteasome of malaria parasites: A multi-stage drug target for chemotherapeutic intervention?
|
2012
|
1.06
|
|
11
|
CYP51 structures and structure-based development of novel, pathogen-specific inhibitory scaffolds.
|
2012
|
1.04
|
|
12
|
Recent advances in candidate-gene and whole-genome approaches to the discovery of anthelmintic resistance markers and the description of drug/receptor interactions.
|
2014
|
1.02
|
|
13
|
Identification of mutations in TgMAPK1 of Toxoplasma gondii conferring resistance to 1NM-PP1.
|
2013
|
1.00
|
|
14
|
Serum albumin and α-1 acid glycoprotein impede the killing of Schistosoma mansoni by the tyrosine kinase inhibitor Imatinib.
|
2014
|
0.97
|
|
15
|
Polymorphism in dhfr/dhps genes, parasite density and ex vivo response to pyrimethamine in Plasmodium falciparum malaria parasites in Thies, Senegal.
|
2013
|
0.93
|
|
16
|
Aminoacyl-tRNA synthetases as drug targets in eukaryotic parasites.
|
2013
|
0.93
|
|
17
|
Identification of β-hematin inhibitors in a high-throughput screening effort reveals scaffolds with in vitro antimalarial activity.
|
2014
|
0.92
|
|
18
|
Nitroimidazole drugs vary in their mode of action in the human parasite Giardia lamblia.
|
2012
|
0.92
|
|
19
|
Repurposing of approved drugs from the human pharmacopoeia to target Wolbachia endosymbionts of onchocerciasis and lymphatic filariasis.
|
2014
|
0.91
|
|
20
|
Nitazoxanide: In vitro and in vivo drug effects against Trichuris muris and Ancylostoma ceylanicum, alone or in combination.
|
2012
|
0.91
|
|
21
|
Praziquantel sensitivity of Kenyan Schistosoma mansoni isolates and the generation of a laboratory strain with reduced susceptibility to the drug.
|
2014
|
0.91
|
|
22
|
Identification of differentially expressed proteins in sulfadiazine resistant and sensitive strains of Toxoplasma gondii using difference-gel electrophoresis (DIGE).
|
2013
|
0.90
|
|
23
|
Anthelmintic resistance in equine nematodes.
|
2014
|
0.90
|
|
24
|
Enzymology of the nematode cuticle: A potential drug target?
|
2014
|
0.89
|
|
25
|
Molecular characterization of the MRPA transporter and antimony uptake in four New World Leishmania spp. susceptible and resistant to antimony.
|
2013
|
0.89
|
|
26
|
Automated, high-throughput, motility analysis in Caenorhabditis elegans and parasitic nematodes: Applications in the search for new anthelmintics.
|
2014
|
0.89
|
|
27
|
Degrees of chloroquine resistance in Plasmodium - is the redox system involved?
|
2012
|
0.89
|
|
28
|
Idiosyncratic quinoline central nervous system toxicity: Historical insights into the chronic neurological sequelae of mefloquine.
|
2014
|
0.89
|
|
29
|
Comparative tissue pharmacokinetics and efficacy of moxidectin, abamectin and ivermectin in lambs infected with resistant nematodes: Impact of drug treatments on parasite P-glycoprotein expression.
|
2012
|
0.89
|
|
30
|
Schistosome ABC multidrug transporters: From pharmacology to physiology.
|
2014
|
0.89
|
|
31
|
Uptake of benzimidazoles by Trichuris suis in vivo in pigs.
|
2014
|
0.89
|
|
32
|
The malaria parasite cation ATPase PfATP4 and its role in the mechanism of action of a new arsenal of antimalarial drugs.
|
2015
|
0.88
|
|
33
|
Utilization of computer processed high definition video imaging for measuring motility of microscopic nematode stages on a quantitative scale: "The Worminator".
|
2014
|
0.88
|
|
34
|
Anthelmintics - from discovery to resistance.
|
2014
|
0.88
|
|
35
|
Genotypic analysis of β-tubulin in Onchocerca volvulus from communities and individuals showing poor parasitological response to ivermectin treatment.
|
2012
|
0.88
|
|
36
|
Chimerization at the AQP2-AQP3 locus is the genetic basis of melarsoprol-pentamidine cross-resistance in clinical Trypanosoma brucei gambiense isolates.
|
2015
|
0.88
|
|
37
|
Drug resistance analysis by next generation sequencing in Leishmania.
|
2014
|
0.87
|
|
38
|
Di-cationic arylimidamides act against Neospora caninum tachyzoites by interference in membrane structure and nucleolar integrity and are active against challenge infection in mice.
|
2012
|
0.87
|
|
39
|
Ion channels and receptor as targets for the control of parasitic nematodes.
|
2011
|
0.87
|
|
40
|
Compound library screening identified Akt/PKB kinase pathway inhibitors as potential key molecules for the development of new chemotherapeutics against schistosomiasis.
|
2014
|
0.87
|
|
41
|
Potential involvement of Brugia malayi cysteine proteases in the maintenance of the endosymbiotic relationship with Wolbachia.
|
2014
|
0.87
|
|
42
|
Confirmation of Fasciola hepatica resistant to triclabendazole in naturally infected Australian beef and dairy cattle.
|
2013
|
0.87
|
|
43
|
Comparative pharmacology of flatworm and roundworm glutamate-gated chloride channels: Implications for potential anthelmintics.
|
2014
|
0.87
|
|
44
|
Untargeted metabolomic analysis of miltefosine action in Leishmania infantum reveals changes to the internal lipid metabolism.
|
2013
|
0.86
|
|
45
|
Application of a resazurin-based high-throughput screening assay for the identification and progression of new treatments for human African trypanosomiasis.
|
2012
|
0.86
|
|
46
|
Kinetic profiling an abundantly expressed planarian serotonergic GPCR identifies bromocriptine as a perdurant antagonist.
|
2016
|
0.86
|
|
47
|
Functional expression of TcoAT1 reveals it to be a P1-type nucleoside transporter with no capacity for diminazene uptake.
|
2013
|
0.86
|
|
48
|
Parasite neuropeptide biology: Seeding rational drug target selection?
|
2011
|
0.86
|
|
49
|
Quantitative proteomic analysis of amphotericin B resistance in Leishmania infantum.
|
2014
|
0.86
|
|
50
|
Synergistic inhibition of Haemonchus contortus exsheathment by flavonoid monomers and condensed tannins.
|
2015
|
0.86
|