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Top papers

Rank Title Journal Year PubWeight™‹?›
1 Use of the endothelin antagonists BQ-123 and PD 142893 to reveal three endothelin receptors mediating smooth muscle contraction and the release of EDRF. Br J Pharmacol 1993 1.29
2 Incomplete inhibition of the pressor effects of endothelin-1 and related peptides in the anaesthetized rat with BQ-123 provides evidence for more than one vasoconstrictor receptor. Br J Pharmacol 1993 1.18
3 Corticotrophin-releasing hormone (CRH)-binding protein interference with CRH antibody binding: implications for direct CRH immunoassay. J Endocrinol 1995 1.06
4 Endothelin-1 release from endothelial cells in culture is elevated both acutely and chronically by short periods of mechanical stretch. Biochem Biophys Res Commun 1994 1.06
5 Endothelin 1 mediates ex vivo coronary vasoconstriction caused by exogenous and endogenous cytokines. Proc Natl Acad Sci U S A 1995 1.05
6 The actions of the peptides, neuropeptide Y and peptide YY, on the vascular and capsular smooth muscle of the isolated, blood-perfused spleen of the dog. Br J Pharmacol 1987 0.99
7 Effects of tumour necrosis factor-alpha in the human forearm: blood flow and endothelin-1 release. Clin Sci (Lond) 2002 0.97
8 Evidence from receptor antagonists of an important role for ETB receptor-mediated vasoconstrictor effects of endothelin-1 in the rat kidney. Br J Pharmacol 1994 0.96
9 Isolation of human met-enkephalin and two groups of putative precursors (2K-pro-met-enkephalin) from an adrenal medullary tumour. Biochem Biophys Res Commun 1980 0.96
10 Purification and characterization of human neuropeptide Y from adrenal-medullary phaeochromocytoma tissue. Biochem J 1984 0.94
11 Oxidative stress participates in the breakdown of neuronal phenotype in experimental diabetic neuropathy. Diabetologia 2001 0.93
12 Simultaneous release of neurotensin, somatostatin, enkephalins and catecholamines from perfused cat adrenal glands. Neuropeptides 1982 0.93
13 Associations between autoantibodies against apolipoprotein B-100 peptides and vascular complications in patients with type 2 diabetes. Diabetologia 2009 0.92
14 Ectopic production of methionine enkephalin and beta-endorphin. Br Med J 1980 0.88
15 Identification of endothelin 1 and big endothelin 1 in secretory vesicles isolated from bovine aortic endothelial cells. Proc Natl Acad Sci U S A 1995 0.87
16 Comparison of the haemodynamic actions of neuropeptide Y, angiotensin II and noradrenaline in anaesthetised cats. Eur J Pharmacol 1986 0.87
17 Comparative studies with the endothelin receptor antagonists BQ-123 and PD 142893 indicate at least three endothelin receptors. J Cardiovasc Pharmacol 1993 0.87
18 Role of hypothalamic neuropeptide Y and orexigenic peptides in anorexia associated with experimental colitis in the rat. Clin Sci (Lond) 2001 0.86
19 Markedly reduced blood pressure responsiveness in endotoxemic rats; reversal by neuropeptide Y. Life Sci 1987 0.86
20 Evidence for vesicles that transport endothelin-1 in bovine aortic endothelial cells. J Cardiovasc Pharmacol 1993 0.86
21 ACTH LPH and related peptides in the ectopic ACTH syndrome. Clin Endocrinol (Oxf) 1980 0.85
22 Large-molecular-weight somatostatin in human adrenal medullary tissue. Biosci Rep 1982 0.85
23 High levels of IgM against methylglyoxal-modified apolipoprotein B100 are associated with less coronary artery calcification in patients with type 2 diabetes. J Intern Med 2011 0.84
24 A molecular model for human Big-Endothelin-1 (Big ET-1). FEBS Lett 1996 0.83
25 Is endothelin-1 the regulator of myofibroblast contraction during wound healing? Lab Invest 1992 0.83
26 Generation by the phosphoramidon-sensitive peptidases, endopeptidase-24.11 and thermolysin, of endothelin-1 and c-terminal fragment from big endothelin-1. Br J Pharmacol 1994 0.83
27 Stress-induced changes of circulating neuropeptide Y in the rat: comparison with catecholamines. Regul Pept 1987 0.83
28 Characterization of the somatostatin-like immunoreactivity extracted from an adrenal medullary tumour. Biosci Rep 1982 0.81
29 Cardiovascular effects of neuropeptide Y. Am J Hypertens 1988 0.81
30 Involvement of neuropeptide Y in neuroendocrine stress responses. Central and peripheral studies. J Neural Transm Suppl 1990 0.81
31 A physiological role for neuropeptide Y in regulating the estrogen/progesterone induced luteinizing hormone surge in ovariectomized rats. Neuroendocrinology 1989 0.81
32 Responses of the rat pituitary-adrenal axis to hypotensive infusions of corticotropin-releasing factor, vasoactive intestinal peptide and other depressor agents. Regul Pept 1991 0.81
33 A lipoic acid-gamma linolenic acid conjugate is effective against multiple indices of experimental diabetic neuropathy. Diabetologia 1998 0.81
34 Endothelin receptor antagonists: actions and rationale for their development. Biochem Pharmacol 1994 0.80
35 Age-related changes in cortico-releasing factor, somatostatin, neuropeptide Y, methionine enkephalin and beta-endorphin in specific rat brain areas. Brain Res 1992 0.79
36 A tissue culture model of the hypophysiotrophic CRF producing neuronal system. Neuroendocrinology 1993 0.79
37 Studies of the role of endothelium-dependent nitric oxide release in the sustained vasodilator effects of corticotrophin releasing factor and sauvagine. Br J Pharmacol 1999 0.78
38 Effect of an antisense oligodeoxynucleotide to endothelin-converting enzyme-1c (ECE-1c) on ECE-1c mRNA, ECE-1 protein and endothelin-1 synthesis in bovine pulmonary artery smooth muscle cells. Mol Pharmacol 2001 0.78
39 The effects of chronic glucocorticoid excess, adrenalectomy and stress on neuropeptide Y in individual rat hypothalamic nuclei. Neuropeptides 1993 0.78
40 Lack of effect of ET antibody or SB 209670 on endotoxin-induced renal failure. J Cardiovasc Pharmacol 1995 0.78
41 Rapid degradation of endothelin-1 by an enzyme released by the rat isolated perfused mesentery. Br J Pharmacol 1995 0.77
42 Vasoconstriction in the rat kidney induced by endothelin-1 is blocked by PD 145065. J Cardiovasc Pharmacol 1993 0.77
43 Effects of dexamethasone on growth hormone (GH)-releasing hormone, arginine- and dopaminergic stimulated GH secretion, and total plasma insulin-like growth factor-I concentrations in normal male volunteers. J Clin Endocrinol Metab 1991 0.77
44 Endothelin-2 synthesis is stimulated by the type-1 tumour necrosis factor receptor and cAMP: comparison with endothelin-converting enzyme-1 expression. J Mol Endocrinol 2000 0.77
45 Heterogeneous receptors mediate endothelin-1-induced changes in blood pressure, hematocrit, and platelet aggregation. J Cardiovasc Pharmacol 1993 0.77
46 Endothelin-1 mediates coronary vasoconstriction caused by exogenous and endogenous cytokines. J Cardiovasc Pharmacol 1995 0.76
47 Pro-opiocortin peptides in rat cerebrospinal fluid. Regul Pept 1985 0.76
48 The p55 tumor necrosis factor receptor (CD120a) induces endothelin-1 synthesis in endothelial and epithelial cells. Eur J Pharmacol 2000 0.76
49 An immunoradiometric assay for the measurement of neuropeptide Y in plasma. Peptides 1986 0.76
50 Comparison of the regulation of endothelin-2 and endothelin-converting enzyme-1 b [correction of beta] by forskolin and TNF-alpha in ACHN cells. J Cardiovasc Pharmacol 1998 0.76
51 Antagonism of renal and systemic responses to endothelin-1 infusion with PD 145065. Eur J Pharmacol 1994 0.76
52 Regional distribution of pro-opiomelanocortin-derived peptides in the human brain. Neuroendocrinology 1984 0.75
53 CRF immunoreactive peptides in the human hypophysis: a cautionary note. Peptides 1985 0.75
54 Contractile activity of endothelin precursors in the isolated gallbladder of the guinea-pig: presence of an endothelin-converting enzyme. Br J Pharmacol 1995 0.75
55 Dexamethasone treatment in man induces changes in 24-hour growth hormone (GH) secretion profile without altering total GH released. J Clin Endocrinol Metab 1991 0.75
56 Neuropeptide Y in multiple endocrine neoplasia: release during surgery for phaeochromocytoma. Clin Endocrinol (Oxf) 1987 0.75
57 Circular dichroism studies of human big-endothelin-1 (Big ET-1). J Pept Res 1997 0.75
58 Effects of glucocorticoid treatment and acute passive immunization with growth hormone-releasing hormone and somatostatin antibodies on endogenous and stimulated growth hormone secretion in the male rat. J Endocrinol 1991 0.75
59 Cloning of bovine preproadrenomedullin and inhibition of its basal expression in vascular endothelial cells by staurosporine. Life Sci 1998 0.75
60 Adrenomedullin acts via stimulation of cyclic AMP and not via calcium signalling in vascular cells in culture. J Hum Hypertens 1996 0.75
61 Adrenomedullin acts as a local mediator of vascular homeostasis through interactions which lead to reduced endothelin-1 synthesis and secretion. J Hum Hypertens 1997 0.75
62 Influence of sodium intake on circulating levels of neuropeptide Y. Life Sci 1987 0.75
63 Stability of pro-opiocortin-related peptides in post-mortem mouse brain tissue. Neuroendocrinology 1982 0.75
64 Plasma levels of neuropeptide tyrosine Y (NPY) are increased in human sepsis but are unchanged during canine endotoxin shock despite raised catecholamine concentrations. J Endocrinol 1988 0.75
65 Demonstration of a neuropeptide Y-like immunoreactivity in human phaeochromocytoma extracts. Regul Pept 1984 0.75
66 Chromatographic characterisation of the circulating neuropeptide Y immunoreactivity from patients with phaeochromocytoma. Regul Pept 1985 0.75
67 Study of the influence of stress and adrenalectomy on central and peripheral neuropeptide Y levels. Comparison with catecholamines. Neuroendocrinology 1989 0.75
68 Pro-enkephalin peptides possessing Met-enkephalin-Arg6-Gly7-Leu8-immunoreactivity in rat CSF, striatum and adrenal gland. Peptides 1985 0.75
69 Stimulation of growth hormone release in man by the potent D2-dopamine agonist CV 205-502: comparison of responses to intravenous and oral administration. J Clin Endocrinol Metab 1990 0.75
70 Met-enkephalin and related peptides in man. Adv Biochem Psychopharmacol 1982 0.75
71 Hydatidiform mole: a case with coexistent fetus. J Kans Med Soc 1978 0.75