Mapping loss of heterozygosity at chromosome 13q: loss at 13q12-q13 is associated with breast tumour progression and poor prognosis.

PubWeight™: 1.28‹?› | Rank: Top 10%

🔗 View Article (PMID 10070314)

Published in Eur J Cancer on December 01, 1998

Authors

G Eiriksdottir1, G Johannesdottir, S Ingvarsson, I B Björnsdottir, J G Jonasson, B A Agnarsson, J Hallgrimsson, J Gudmundsson, V Egilsson, H Sigurdsson, R B Barkardottir

Author Affiliations

1: Department of Pathology, University and National Hospital of Iceland, Reykjavik, Iceland.

Articles citing this

Mir-17-5p regulates breast cancer cell proliferation by inhibiting translation of AIB1 mRNA. Mol Cell Biol (2006) 3.71

A cyclin D1/microRNA 17/20 regulatory feedback loop in control of breast cancer cell proliferation. J Cell Biol (2008) 3.02

MicroRNAs and their target gene networks in breast cancer. Breast Cancer Res (2010) 2.83

MicroRNA: Biogenesis, Function and Role in Cancer. Curr Genomics (2010) 2.80

The estrogen receptor-alpha-induced microRNA signature regulates itself and its transcriptional response. Proc Natl Acad Sci U S A (2009) 2.29

Somatic deletions in hereditary breast cancers implicate 13q21 as a putative novel breast cancer susceptibility locus. Proc Natl Acad Sci U S A (2000) 1.66

PCDH8, the human homolog of PAPC, is a candidate tumor suppressor of breast cancer. Oncogene (2008) 1.54

"Myc'ed messages": myc induces transcription of E2F1 while inhibiting its translation via a microRNA polycistron. PLoS Genet (2007) 1.45

The proto-oncogene LRF is under post-transcriptional control of MiR-20a: implications for senescence. PLoS One (2008) 1.37

microRNA, cell cycle, and human breast cancer. Am J Pathol (2010) 1.32

Regulation of breast cancer and bone metastasis by microRNAs. Dis Markers (2013) 1.12

miR-20a and miR-290, multi-faceted players with a role in tumourigenesis and senescence. J Cell Mol Med (2010) 0.93

MicroRNA-18a inhibits hypoxia-inducible factor 1α activity and lung metastasis in basal breast cancers. Breast Cancer Res (2014) 0.92

miR-17/20 sensitization of breast cancer cells to chemotherapy-induced apoptosis requires Akt1. Oncotarget (2014) 0.92

Restoration of miR17/20a in solid tumor cells enhances the natural killer cell antitumor activity by targeting Mekk2. Cancer Immunol Res (2014) 0.84

Quantitatively controlling expression of miR-17~92 determines colon tumor progression in a mouse tumor model. Am J Pathol (2014) 0.83

MicroRNA-363 targets myosin 1B to reduce cellular migration in head and neck cancer. BMC Cancer (2015) 0.79

Genomic instability at the 13q31 locus and somatic mtDNA mutation in the D-loop site correlate with tumor aggressiveness in sporadic Brazilian breast cancer cases. Clinics (Sao Paulo) (2012) 0.76

MicroRNA-17 is downregulated in esophageal adenocarcinoma cancer stem-like cells and promotes a radioresistant phenotype. Oncotarget (2017) 0.75

MicroRNA-18a inhibits ovarian cancer growth via directly targeting TRIAP1 and IPMK. Oncol Lett (2017) 0.75

Articles by these authors

Multifactorial analysis of differences between sporadic breast cancers and cancers involving BRCA1 and BRCA2 mutations. J Natl Cancer Inst (1998) 6.06

Respiration as the main determinant of carbon balance in European forests. Nature (2000) 5.07

A single BRCA2 mutation in male and female breast cancer families from Iceland with varied cancer phenotypes. Nat Genet (1996) 4.38

An evaluation of genetic heterogeneity in 145 breast-ovarian cancer families. Breast Cancer Linkage Consortium. Am J Hum Genet (1995) 3.81

High prevalence of the 999del5 mutation in icelandic breast and ovarian cancer patients. Cancer Res (1996) 2.43

Risk of prostate, ovarian, and endometrial cancer among relatives of women with breast cancer. BMJ (1992) 2.39

Study of a single BRCA2 mutation with high carrier frequency in a small population. Am J Hum Genet (1997) 2.28

Different tumor types from BRCA2 carriers show wild-type chromosome deletions on 13q12-q13. Cancer Res (1995) 2.14

HER-2/neu amplification predicts poor survival in node-positive breast cancer. Cancer Res (1990) 2.14

Distinct somatic genetic changes associated with tumor progression in carriers of BRCA1 and BRCA2 germ-line mutations. Cancer Res (1997) 2.03

Familial male breast cancer is not linked to the BRCA1 locus on chromosome 17q. Nat Genet (1994) 1.88

Tumour biological features of BRCA1-induced breast and ovarian cancer. Eur J Cancer (1997) 1.82

Consistent chromosome 3p deletion and loss of heterozygosity in renal cell carcinoma. Proc Natl Acad Sci U S A (1988) 1.76

Frequent occurrence of BRCA2 linkage in Icelandic breast cancer families and segregation of a common BRCA2 haplotype. Am J Hum Genet (1996) 1.75

Loss of heterozygosity at chromosome 1p in different solid human tumours: association with survival. Br J Cancer (1999) 1.71

Genetic heterogeneity of breast-ovarian cancer revisited. Breast Cancer Linkage Consortium. Am J Hum Genet (1995) 1.68

Somatic deletions in hereditary breast cancers implicate 13q21 as a putative novel breast cancer susceptibility locus. Proc Natl Acad Sci U S A (2000) 1.66

Racial variation in the O-acetylation phenotype of human colonic mucosa. J Pathol (1994) 1.62

Rapid detection of Chlamydia trachomatis by an enzyme immunoassay method. Diagn Microbiol Infect Dis (1986) 1.50

c-myc amplification is an independent prognostic factor in postmenopausal breast cancer. Int J Cancer (1992) 1.46

Linkage analysis of chromosome 17q markers and breast-ovarian cancer in Icelandic families, and possible relationship to prostatic cancer. Am J Hum Genet (1993) 1.38

The accuracy of death certificates. Implications for health statistics. Virchows Arch A Pathol Anat Histopathol (1991) 1.28

ERBB2 amplification in breast cancer with a high rate of proliferation. Oncogene (1991) 1.27

The effect of a single BRCA2 mutation on cancer in Iceland. J Med Genet (2002) 1.26

HER2/neu amplification and comedo type breast carcinoma. Lancet (1989) 1.22

Linkage to BRCA2 region in hereditary male breast cancer. Lancet (1995) 1.21

BRCA2 and p53 mutations in primary breast cancer in relation to genetic instability. Cancer Res (1998) 1.20

Association of INT2/HST1 coamplification in primary breast cancer with hormone-dependent phenotype and poor prognosis. Br J Cancer (1991) 1.20

Altered expression of E-cadherin in breast cancer. patterns, mechanisms and clinical significance. Eur J Cancer (2000) 1.14

Meningiona of the neck. Case report. J Neurosurg (1970) 1.12

ERBB2 amplification is associated with tamoxifen resistance in steroid-receptor positive breast cancer. Cancer Lett (1994) 1.11

Natural infestation of the chewing lice (Werneckiella equi) on horses and treatment with imidacloprid and phoxim. Parasitol Res (2004) 1.09

Immunohistochemical evidence of a role for transforming growth factor beta in the pathogenesis of nodular sclerosing Hodgkin's disease. Am J Pathol (1990) 1.08

Chromosome 17q-linkage seems to be infrequent in Icelandic families at risk of breast cancer. Acta Oncol (1995) 1.05

Identification of a novel splice-site mutation of the BRCA1 gene in two breast cancer families: screening reveals low frequency in Icelandic breast cancer patients. Hum Mutat (1998) 1.05

Second primary cancers among 109 000 cases of non-Hodgkin's lymphoma. Br J Cancer (2005) 1.04

Loss of heterozygosity at chromosome 11 in breast cancer: association of prognostic factors with genetic alterations. Br J Cancer (1995) 1.04

Chromosome alterations and E-cadherin gene mutations in human lobular breast cancer. Br J Cancer (1999) 1.04

Adjuvant chemotherapy with doxorubicin in high-grade soft tissue sarcoma: a randomized trial of the Scandinavian Sarcoma Group. J Clin Oncol (1989) 1.03

Infestation of Werneckiella equi on Icelandic horses, characteristics of predilection sites and lice dermatitis. Parasitol Res (2005) 1.02

Risk of lymphoma in patients with dermatitis herpetiformis. BMJ (1994) 1.01

Flow cytometric DNA index and S-phase fraction in breast cancer in relation to other prognostic variables and to clinical outcome. Acta Oncol (1992) 1.01

High frequency of LOH, MSI and abnormal expression of FHIT in gastric cancer. Eur J Cancer (2002) 1.00

Reduced Fhit expression in sporadic and BRCA2-linked breast carcinomas. Cancer Res (1999) 0.99

Eruption of the nevado del ruiz volcano, Colombia, on 13 november 1985: tephra fall and lahars. Science (1986) 0.99

Male breast cancer in Iceland. Int J Cancer (1996) 0.99

Primary cytomegalovirus infection and gastric ulcers in normal host. Dig Dis Sci (1991) 0.99

The importance of strain variation in virulence of Candida dubliniensis and Candida albicans: results of a blinded histopathological study of invasive candidiasis. Clin Microbiol Infect (2009) 0.98

Gastric cancer after gastrectomy. Int J Cancer (1988) 0.98

Radiographic and clinical survey of degenerative joint disease in the distal tarsal joints in Icelandic horses. Equine Vet J (2000) 0.97

Second primary malignancies in patients with male breast cancer. Br J Cancer (2005) 0.96

High frequency of allelic imbalance at chromosome region 16q22-23 in human breast cancer: correlation with high PgR and low S phase. Int J Cancer (1995) 0.95

Haplotype analysis in Icelandic and Finnish BRCA2 999del5 breast cancer families. Eur J Hum Genet (2001) 0.95

pT4 stage II and III colon cancers carry the worst prognosis in a nationwide survival analysis. Shepherd's local peritoneal involvement revisited. Int J Cancer (2014) 0.94

Alterations of E-cadherin and beta-catenin in gastric cancer. BMC Cancer (2001) 0.94

Loss of heterozygosity at chromosome 7q in human breast cancer: association with clinical variables. Anticancer Res (1997) 0.94

The effect of mismatch repair deficiency on tumourigenesis; microsatellite instability affecting genes containing short repeated sequences. Int J Oncol (2000) 0.94

Replication error in colorectal carcinoma: association with loss of heterozygosity at mismatch repair loci and clinicopathological variables. Anticancer Res (1999) 0.93

The volume-deficient orbit: clinical characteristics, surgical management, and results after extraperiorbital implantation of Silastic block. Br J Ophthalmol (1990) 0.93

BRCA1 and BRCA2 mutation status and cancer family history of Danish women affected with multifocal or bilateral breast cancer at a young age. J Med Genet (2001) 0.92