Cleavage of the cyclohexyl-subunit of rapamycin results in loss of immunosuppressive activity.

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Published in Bioorg Med Chem Lett on February 08, 1999

Authors

R Sedrani1, L H Jones, A M Jutzi-Eme, W Schuler, S Cottens

Author Affiliations

1: Novartis Pharma AG, Preclinical Research, Basel, Switzerland. richard.sedrani@pharma.novartis.com

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