Published in JAMA on April 14, 1999
Meta-analysis of naltrexone and acamprosate for treating alcohol use disorders: when are these medications most helpful? Addiction (2012) 2.64
Trust, performance management and the new GP contract. Br J Gen Pract (2003) 1.72
Client and counselor attitudes toward the use of medications for treatment of opioid dependence. J Subst Abuse Treat (2006) 1.61
Long-term outcome of in-patients with substance use disorders: A study from North India. Indian J Psychiatry (2008) 1.52
Genetically selected Marchigian Sardinian alcohol-preferring (msP) rats: an animal model to study the neurobiology of alcoholism. Addict Biol (2006) 1.47
The BRENDA model: integrating psychosocial treatment and pharmacotherapy for the treatment of alcohol use disorders. J Psychiatr Pract (2006) 1.19
Abstinence following alcohol drinking produces depression-like behavior and reduced hippocampal neurogenesis in mice. Neuropsychopharmacology (2008) 1.19
Proof-of-concept human laboratory study for protracted abstinence in alcohol dependence: effects of gabapentin. Addict Biol (2008) 1.17
Facilitating factors and barriers to the use of medications in publicly funded addiction treatment organizations. J Addict Med (2010) 1.15
Alcoholic liver disease. Postgrad Med J (2000) 1.13
New insights into the efficacy of naltrexone based on trajectory-based reanalyses of two negative clinical trials. Biol Psychiatry (2007) 1.12
Baclofen blocks expression and sensitization of anxiety-like behavior in an animal model of repeated stress and ethanol withdrawal. Alcohol Clin Exp Res (2007) 1.12
Glutamatergic targets for new alcohol medications. Psychopharmacology (Berl) (2013) 1.10
An inpatient treatment and discharge planning protocol for alcohol dependence: efficacy in reducing 30-day readmissions and emergency department visits. J Gen Intern Med (2014) 1.07
Alcohol abuse and pulmonary disease. J Leukoc Biol (2009) 1.06
Treatment of alcoholic liver disease. Therap Adv Gastroenterol (2011) 1.06
How can we use our knowledge of alcohol-tobacco interactions to reduce alcohol use? Annu Rev Clin Psychol (2012) 1.01
Treatment outcomes in type A and B alcohol dependence 6 months after serotonergic pharmacotherapy. Alcohol Clin Exp Res (2004) 0.99
Understanding attitudes towards use of medication in substance abuse treatment: A multilevel approach. Psychol Serv (2009) 0.96
Role of the serotonergic system in alcohol dependence: from animal models to clinics. Prog Mol Biol Transl Sci (2011) 0.93
Gender differences in predictors of treatment attrition with high dose naltrexone in cocaine and alcohol dependence. Am J Addict (2008) 0.93
Adoption of medications in substance abuse treatment: priorities and strategies of single state authorities. J Psychoactive Drugs (2010) 0.93
Substance abuse among older adults. Clin Geriatr Med (2014) 0.93
A Prospective 5-Year Re-examination of Alcohol Response in Heavy Drinkers Progressing in Alcohol Use Disorder. Biol Psychiatry (2015) 0.92
Alcohol consumption and development of acute respiratory distress syndrome: a population-based study. Int J Environ Res Public Health (2009) 0.91
When should clinicians switch treatments? An application of signal detection theory to two treatments for women with alcohol use disorders. Behav Res Ther (2010) 0.89
Psychotic spectrum disorders and alcohol abuse: a review of pharmacotherapeutic strategies and a report on the effectiveness of naltrexone and disulfiram. Schizophr Bull (2006) 0.87
Practitioner review: adolescent alcohol use disorders: assessment and treatment issues. J Child Psychol Psychiatry (2008) 0.86
The overlap between binge eating disorder and substance use disorders: Diagnosis and neurobiology. J Behav Addict (2013) 0.84
Naloxone does not attenuate the locomotor effects of ethanol in FAST, SLOW, or two heterogeneous stocks of mice. Psychopharmacology (Berl) (2005) 0.84
Alcoholic Hepatitis. Curr Treat Options Gastroenterol (2004) 0.84
Placebo group improvement in trials of pharmacotherapies for alcohol use disorders: a multivariate meta-analysis examining change over time. J Clin Psychopharmacol (2013) 0.84
Molecular targets of alcohol action: Translational research for pharmacotherapy development and screening. Prog Mol Biol Transl Sci (2011) 0.83
A pilot study comparing in-person and web-based motivational interviewing among adults with a first-time DUI offense. Addict Sci Clin Pract (2015) 0.82
Pharmacotherapy for alcohol dependence: anticraving medications for relapse prevention. Yonsei Med J (2006) 0.81
Genetically selected alcohol preferring rats to model human alcoholism. Curr Top Behav Neurosci (2013) 0.81
Galantamine: a cholinergic patch in the treatment of alcoholism: a randomized, placebo-controlled trial. Psychopharmacology (Berl) (2005) 0.80
Optimal management for alcoholic liver disease: Conventional medications, natural therapy or combination? World J Gastroenterol (2016) 0.80
A randomized, controlled, pilot study of acamprosate added to escitalopram in adults with major depressive disorder and alcohol use disorder. J Clin Psychopharmacol (2012) 0.79
Therapeutic options and challenges for substances of abuse. Dialogues Clin Neurosci (2007) 0.79
The Current State of Pharmacological Treatments for Cannabis Use Disorder and Withdrawal. Neuropsychopharmacology (2017) 0.79
Low-dose prazosin alone and in combination with propranolol or naltrexone: effects on ethanol and sucrose seeking and self-administration in the P rat. Psychopharmacology (Berl) (2015) 0.78
Ondansetron and sertraline may interact with 5-HTTLPR and DRD4 polymorphisms to reduce drinking in non-treatment seeking alcohol-dependent women: exploratory findings. Alcohol (2014) 0.76
Treatment for comorbid borderline personality disorder and alcohol use disorders: a review of the evidence and future recommendations. Exp Clin Psychopharmacol (2012) 0.76
Acamprosate: a new tool in the battle against alcohol dependence. Neuropsychiatr Dis Treat (2006) 0.76
Treatment of decompensated alcoholic liver disease. Int J Hepatol (2011) 0.76
Alcohol liver disease: A review of current therapeutic approaches to achieve long-term abstinence. World J Gastroenterol (2015) 0.76
Alcohol and primary care--will an emphasis upon harm reduction engage general practitioners? Br J Gen Pract (2003) 0.75
Recent Advances in Nicotinic Receptor Signaling in Alcohol Abuse and Alcoholism. Prog Mol Biol Transl Sci (2015) 0.75
Pharmacotherapy for Alcohol Use Disorders: Physicians' Perceptions and Practices. Front Psychiatry (2016) 0.75
Systematic review of the pharmacological treatment of alcohol use disorders in individuals infected with hepatitis C. Addict Sci Clin Pract (2015) 0.75
Chronic alcohol exposure increases ganglia endogenous morphine levels. Arch Med Sci (2010) 0.75
Treatment for alcohol related problems. BMJ (2005) 0.75
Involvement of delta opioid receptors in alcohol withdrawal-induced mechanical allodynia in male C57BL/6 mice. Drug Alcohol Depend (2016) 0.75
Pharmacoprophylaxis of alcohol dependence: Review and update Part II: Efficacy. Indian J Psychiatry (2007) 0.75
Alcoholic cardiomyopathy : The result of dosage and individual predisposition. Herz (2016) 0.75
Is there evidence for effectiveness of acamprosate in maintaining abstinence in alcohol dependent patients? Psychiatry (Edgmont) (2005) 0.75
Exploration of Core Symptoms for the Diagnosis of Alcohol Dependence in the ICD-10. Alcohol Clin Exp Res (2016) 0.75
Oral operant ethanol self-administration in the absence of explicit cues, food restriction, water restriction and ethanol fading in C57BL/6J mice. Psychopharmacology (Berl) (2015) 0.75
Commentary: Doxasozin for alcoholism. Alcohol Clin Exp Res (2012) 0.75
Impact of socioeconomic status on hospital use in New York City. Health Aff (Millwood) (1993) 8.33
Current methods of the US Preventive Services Task Force: a review of the process. Am J Prev Med (2001) 7.94
Similar effectiveness of paroxetine, fluoxetine, and sertraline in primary care: a randomized trial. JAMA (2001) 6.66
Community-based participatory research: assessing the evidence. Evid Rep Technol Assess (Summ) (2004) 6.13
Perinatal depression: prevalence, screening accuracy, and screening outcomes. Evid Rep Technol Assess (Summ) (2005) 6.10
Does free care improve adults' health? Results from a randomized controlled trial. N Engl J Med (1983) 5.10
The effects of having a regular doctor on access to primary care. Med Care (1996) 3.56
Literacy and health outcomes. Evid Rep Technol Assess (Summ) (2004) 3.15
Outcome measurement: concepts and questions. Inquiry (1988) 2.95
Use of medical care in the Rand Health Insurance Experiment. Diagnosis- and service-specific analyses in a randomized controlled trial. Med Care (1986) 2.70
Choosing measures of health status for individuals in general populations. Am J Public Health (1981) 2.60
Clinical course of anti-neutrophil cytoplasmic autoantibody-associated glomerulonephritis and systemic vasculitis. The Glomerular Disease Collaborative Network. Ann Intern Med (1990) 2.49
Persuasive communication and medical technology assessment. Arch Intern Med (1985) 2.41
Systems to rate the strength of scientific evidence. Evid Rep Technol Assess (Summ) (2002) 2.33
Efficacy, effectiveness, variations, and quality. Boundary-crossing research. Med Care (1985) 2.32
Risk factors for gallbladder cancer. An international collaborative case-control study. Cancer (1995) 1.98
Evaluation of the Medicaid competition demonstrations. Health Care Financ Rev (1989) 1.98
Risk factors and outcome of hospital-acquired acute renal failure. Clinical epidemiologic study. Am J Med (1987) 1.93
Using computers to identify complications after surgery. Am J Public Health (1985) 1.84
Making the transition from information systems of the 1970s to medical information systems of the 1990s: the role of the physician's workstation. J Med Syst (1991) 1.80
The association of nonsteroidal anti-inflammatory drugs with upper gastrointestinal tract bleeding. Arch Intern Med (1987) 1.79
Concanavalin A stimulates phospholipid methylation and phosphatidylserine decarboxylation in rat mast cells. Proc Natl Acad Sci U S A (1979) 1.79
Differences among hospitals in Medicare patient mortality. Health Serv Res (1989) 1.69
Population-based health principles in medical and public health practice. J Public Health Manag Pract (2001) 1.66
Sexual activity, contraceptive use, and other risk factors for symptomatic and asymptomatic bacteriuria. A case-control study. Ann Intern Med (1987) 1.60
Binge ethanol exposure in adult rats causes necrotic cell death. Alcohol Clin Exp Res (2002) 1.53
Quality of care in episodes of respiratory illness among Medicaid patients in New Mexico. Ann Intern Med (1980) 1.52
Randomized controlled trials in surgery: an essential component of scientific progress. Spine (Phila Pa 1976) (1999) 1.42
Training in back care to improve outcome and patient satisfaction. Teaching old docs new tricks. J Fam Pract (2000) 1.42
Can a back pain screening tool help classify patients with acute pain into risk levels for chronic pain? Eur J Pain (2015) 1.42
Methotrexate polyglutamates as a marker of patient compliance and clinical response in psoriasis: a single-centre prospective study. Br J Dermatol (2012) 1.39
The relative gastrointestinal toxicity of the nonsteroidal anti-inflammatory drugs. Arch Intern Med (1987) 1.38
IgE-mediated histamine release in rat basophilic leukemia cells: receptor activation, phospholipid methylation, Ca2+ flux, and release of arachidonic acid. Arch Biochem Biophys (1981) 1.34
The Physician's Workstation: an example of end user integration of information systems. Proc Annu Symp Comput Appl Med Care (1991) 1.33
Selective criteria may increase lumbosacral spine roentgenogram use in acute low-back pain. Arch Intern Med (1989) 1.29
Induction of Fos-like proteins and ultrasonic vocalizations during ethanol withdrawal: further evidence for withdrawal-induced anxiety. Alcohol Clin Exp Res (1998) 1.28
Variants of the rat basophilic leukemia cell line for the study of histamine release. Fed Proc (1982) 1.28
Effect of cost-sharing on the use of medical services by children: interim results from a randomized controlled trial. Pediatrics (1985) 1.23
Phospholipid methylation affects immunoglobulin E-mediated histamine and arachidonic acid release in rat leukemia basophils. Biochem Biophys Res Commun (1980) 1.23
Adolescent binge drinking increases expression of the danger signal receptor agonist HMGB1 and Toll-like receptors in the adult prefrontal cortex. Neuroscience (2012) 1.20
Guanine nucleotides stimulate production of inositol trisphosphate in rat cortical membranes. Biochem J (1985) 1.19
Induction of cyclooxygenase-2 in brain during acute and chronic ethanol treatment and ethanol withdrawal. Alcohol Clin Exp Res (1999) 1.16
Identification and properties of methyltransferases that synthesize phosphatidylcholine in rat brain synaptosomes. J Neurochem (1980) 1.16
Distinct cell proliferation events during abstinence after alcohol dependence: microglia proliferation precedes neurogenesis. Neurobiol Dis (2008) 1.16
Use of insurance claims data in measuring quality of care. Int J Technol Assess Health Care (1990) 1.13
Physician-based diet counseling for cholesterol reduction: current practices, determinants, and strategies for improvement. Prev Med (1993) 1.13
High prevalence of subtle and severe menstrual disturbances in exercising women: confirmation using daily hormone measures. Hum Reprod (2009) 1.12
Characterization of the cholinergic stimulation of phosphoinositide hydrolysis in rat brain slices. J Neurosci (1984) 1.12
Association between sweet preference and paternal history of alcoholism in psychiatric and substance abuse patients. Alcohol Clin Exp Res (2003) 1.10
Ethanol tolerance and synaptic plasticity. Trends Pharmacol Sci (1998) 1.09
Sweet liking, novelty seeking, and gender predict alcoholic status. Alcohol Clin Exp Res (2004) 1.08
Monitoring quality of care in the Medicare program. Two proposed systems. JAMA (1987) 1.08
The virtual standardized patient. Simulated patient-practitioner dialog for patient interview training. Stud Health Technol Inform (2000) 1.06
Effects of nicotine on ethanol dependence and brain damage. Alcohol (2001) 1.05
Serum CEA and CA 19-9: potential future diagnostic or screening tests for gallbladder cancer? Int J Cancer (1990) 1.05
Physical therapy utilization by patients with acute low back pain. Phys Ther (1997) 1.05
The effect of cost sharing on the use of antibiotics in ambulatory care: results from a population-based randomized controlled trial. J Chronic Dis (1987) 1.04
Low bone mineral density and fractures in stages 3-5 CKD: an updated systematic review and meta-analysis. Osteoporos Int (2014) 1.03
Characterization of the effects of phorbol esters on rat mast cell secretion. J Immunol (1985) 1.03
Assessing "best evidence": issues in grading the quality of studies for systematic reviews. Jt Comm J Qual Improv (1999) 1.03
Screening and treating adults for lipid disorders. Am J Prev Med (2001) 1.02
Regional specificity of ethanol and NMDA action in brain revealed with FOS-like immunohistochemistry and differential routes of drug administration. Alcohol Clin Exp Res (2001) 1.01
Ethanol inhibits NMDA receptor-mediated excitotoxicity in rat primary neuronal cultures. Alcohol Clin Exp Res (1993) 1.01
Periadolescent ethanol exposure reduces adult forebrain ChAT+IR neurons: correlation with behavioral pathology. Neuroscience (2011) 1.01
Neurotoxicity and neurocognitive impairments with alcohol and drug-use disorders: potential roles in addiction and recovery. Alcohol Clin Exp Res (2001) 0.99
Quality of ambulatory care. Epidemiology and comparison by insurance status and income. Med Care (1990) 0.99
Fracture risk assessment in patients with chronic kidney disease. Osteoporos Int (2011) 0.99
Rat basophilic leukemia cell lines defective in phospholipid methyltransferase enzymes, Ca2+ influx, and histamine release: reconstitution by hybridization. Proc Natl Acad Sci U S A (1981) 0.98
Oral contraceptives and other risk factors for gallbladder disease. Clin Pharmacol Ther (1986) 0.98
Bone mineral density by DXA and HR pQCT can discriminate fracture status in men and women with stages 3 to 5 chronic kidney disease. Osteoporos Int (2012) 0.98
Ethanol enhances the endothelial nitric oxide synthase response to agonists. Hypertension (1993) 0.97
Training primary care physicians to give limited manual therapy for low back pain: patient outcomes. Spine (Phila Pa 1976) (2000) 0.97
Proof and policy from medical research evidence. J Health Polit Policy Law (2001) 0.97
Practitioner self-confidence and patient outcomes in acute low back pain. Arch Fam Med (1998) 0.95
The role of the primary physician in disability determination for Social Security insurance and workers' compensation. Ann Intern Med (1986) 0.93
Chronic disease in a general adult population. Findings from the Rand Health Insurance Experiment. West J Med (1986) 0.93
Periadolescent ethanol vapor exposure persistently reduces measures of hippocampal neurogenesis that are associated with behavioral outcomes in adulthood. Neuroscience (2013) 0.93
Chronic ethanol increases N-methyl-D-aspartate-stimulated nitric oxide formation but not receptor density in cultured cortical neurons. Mol Pharmacol (1997) 0.93
Healthcare use among U.S. women aged 45 and older: total costs and costs for selected postmenopausal health risks. J Womens Health Gend Based Med (1999) 0.92
Rapid decrease in rat brain beta adrenergic receptor binding during combined antidepressant alpha-2 antagonist treatment. J Pharmacol Exp Ther (1983) 0.92
Phospholipase activation in the IgE-mediated and Ca2+ ionophore A23187-induced release of histamine from rat basophilic leukemia cells. Arch Biochem Biophys (1981) 0.92
Finding cancer in primary care outpatients with low back pain: a comparison of diagnostic strategies. J Gen Intern Med (2001) 0.91
Consequences of cost-sharing for children's health. Pediatrics (1985) 0.91
Progress report on the clinical workstation and clinical data repository at UNC Hospitals. Proc Annu Symp Comput Appl Med Care (1993) 0.90
Variations in hypertension control in indigent rural primary care clinics in North Carolina. Arch Fam Med (1994) 0.90
Suppression of alcohol intake by chronic naloxone treatment in P rats: tolerance development and elevation of opiate receptor binding. Alcohol Clin Exp Res (1999) 0.90
The influence of indemnification by workers' compensation insurance on recovery from acute backache. North Carolina Back Pain Project. Spine (Phila Pa 1976) (1995) 0.88
The findings of the Rand Health Insurance experiment--a response to Welch et al. Med Care (1987) 0.88
The effect of indication on hypersensitivity reactions associated with zomepirac sodium and other nonsteroidal antiinflammatory drugs. Arthritis Rheum (1987) 0.88
Applying cognitive design principles to formatting HRQOL instruments. Qual Life Res (2000) 0.88
The epidemiology of the acute flank pain syndrome from suprofen. Clin Pharmacol Ther (1989) 0.88
Angiotensin II receptor subtypes play opposite roles in regulating phosphatidylinositol hydrolysis in rat skin slices. Biochem Biophys Res Commun (1992) 0.88
NMDA receptor binding in adult rat brain after several chronic ethanol treatment protocols. Alcohol Clin Exp Res (1997) 0.88
Presynaptic alpha-receptor subsensitivity after long-term antidepressant treatment. Science (1978) 0.87
Further selection of rat lines differing in 5-HT-1A receptor sensitivity: behavioral and functional correlates. Psychiatr Genet (1996) 0.87
The clinical utility of FRAX to discriminate fracture status in men and women with chronic kidney disease. Osteoporos Int (2013) 0.87
From the Institute of Medicine. JAMA (1996) 0.86
Acetylation phenotypes and environmental chemical exposure of people with idiopathic systemic lupus erythematosus. Arthritis Rheum (1993) 0.86