Published in Gastroenterology on May 01, 1999
Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a). Mol Cell Biol (2001) 5.78
Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells. Nature (2013) 4.57
Transforming growth factor beta contributes to progressive diabetic nephropathy. Proc Natl Acad Sci U S A (2000) 1.61
Strategic attack on host cell gene expression during adenovirus infection. J Virol (2003) 1.21
Deranged transcriptional regulation of cell-volume-sensitive kinase hSGK in diabetic nephropathy. Proc Natl Acad Sci U S A (2000) 1.20
Crystal structure of the kinase domain of serum and glucocorticoid-regulated kinase 1 in complex with AMP PNP. Protein Sci (2007) 1.11
Tonicity-dependent induction of Sgk1 expression has a potential role in dehydration-induced natriuresis in rodents. J Clin Invest (2009) 1.05
Distribution and regulation of expression of serum- and glucocorticoid-induced kinase-1 in the rat kidney. J Physiol (2003) 1.00
Multiple translational isoforms give functional specificity to serum- and glucocorticoid-induced kinase 1. Mol Biol Cell (2007) 0.99
Circulating transforming growth factor-beta1 levels and the risk for kidney disease in African Americans. Kidney Int (2009) 0.98
Intestinal phosphate transport. Adv Chronic Kidney Dis (2011) 0.94
Importin-alpha mediates the regulated nuclear targeting of serum- and glucocorticoid-inducible protein kinase (Sgk) by recognition of a nuclear localization signal in the kinase central domain. Mol Biol Cell (2003) 0.93
Regulation of KCNE1-dependent K(+) current by the serum and glucocorticoid-inducible kinase (SGK) isoforms. Pflugers Arch (2002) 0.90
SGK1-sensitive renal tubular glucose reabsorption in diabetes. Am J Physiol Renal Physiol (2009) 0.88
Sodium chloride, SGK1, and Th17 activation. Pflugers Arch (2014) 0.86
Serum and glucocorticoid-regulated kinase 1 regulates neutrophil clearance during inflammation resolution. J Immunol (2014) 0.85
Renal tubular transport and the genetic basis of hypertensive disease. Clin Exp Nephrol (2005) 0.85
The N-terminus of the serum- and glucocorticoid-inducible kinase Sgk1 specifies mitochondrial localization and rapid turnover. Biochem J (2006) 0.84
Decreased intestinal glucose transport in the sgk3-knockout mouse. Pflugers Arch (2005) 0.83
Effects of kinase inhibitors on TGF-beta induced upregulation of Kv1.3 K+ channels in brain macrophages. Pflugers Arch (2003) 0.83
Inhibition of serum- and glucocorticoid-inducible kinase 1 enhances TLR-mediated inflammation and promotes endotoxin-driven organ failure. FASEB J (2015) 0.82
Small bowel review: normal physiology part 2. Dig Dis Sci (2001) 0.81
Serine/threonine protein kinase SGK1 in glucocorticoid-dependent transdifferentiation of pancreatic acinar cells to hepatocytes. J Cell Sci (2011) 0.81
Role of the serum and glucocorticoid inducible kinase SGK1 in glucocorticoid stimulation of gastric acid secretion. Pflugers Arch (2007) 0.81
Serum- and glucocorticoid-inducible kinase 1 in the regulation of renal and extrarenal potassium transport. Clin Exp Nephrol (2011) 0.79
Organotypical tissue cultures from adult murine colon as an in vitro model of intestinal mucosa. Histochem Cell Biol (2008) 0.79
Serum and Glucocorticoid Regulated Kinase 1 in Sodium Homeostasis. Int J Mol Sci (2016) 0.78
Stimulation of electrogenic intestinal dipeptide transport by the glucocorticoid dexamethasone. Pflugers Arch (2009) 0.78
The stimulus-dependent co-localization of serum- and glucocorticoid-regulated protein kinase (Sgk) and Erk/MAPK in mammary tumor cells involves the mutual interaction with the importin-alpha nuclear import protein. Exp Cell Res (2007) 0.77
Gene expression study of monocytes/macrophages during early foreign body reaction and identification of potential precursors of myofibroblasts. PLoS One (2010) 0.77
SGK1-dependent stimulation of intestinal SGLT1 activity by vitamin D. Pflugers Arch (2011) 0.77
Down-regulation of serum/glucocorticoid regulated kinase 1 in colorectal tumours is largely independent of promoter hypermethylation. PLoS One (2010) 0.76
Fluvastatin inhibits the expression of fibronectin in human peritoneal mesothelial cells induced by high-glucose peritoneal dialysis solution via SGK1 pathway. Clin Exp Nephrol (2014) 0.75
miR-17∼92 family clusters control iNKT cell ontogenesis via modulation of TGF-β signaling. Proc Natl Acad Sci U S A (2016) 0.75
Complete nucleotide sequence of infectious Coxsackievirus B3 cDNA: two initial 5' uridine residues are regained during plus-strand RNA synthesis. J Virol (1990) 2.68
Molecular cloning of the genome of a cardiotropic Coxsackie B3 virus: full-length reverse-transcribed recombinant cDNA generates infectious virus in mammalian cells. Proc Natl Acad Sci U S A (1985) 2.67
The low-affinity monocarboxylate transporter MCT4 is adapted to the export of lactate in highly glycolytic cells. Biochem J (2000) 2.59
Ultrahigh resolution drug design I: details of interactions in human aldose reductase-inhibitor complex at 0.66 A. Proteins (2004) 2.51
Molecular typing of enteroviruses: current status and future requirements. The European Union Concerted Action on Virus Meningitis and Encephalitis. Clin Microbiol Rev (1998) 2.48
Ongoing enterovirus-induced myocarditis is associated with persistent heart muscle infection: quantitative analysis of virus replication, tissue damage, and inflammation. Proc Natl Acad Sci U S A (1992) 2.38
Detection and typing of human papillomavirus by e6 nested multiplex PCR. J Clin Microbiol (2004) 2.34
Evidence that HERV-K is the endogenous retrovirus sequence that codes for the human teratocarcinoma-derived retrovirus HTDV. Virology (1993) 2.32
An atypical variant of Fabry's disease with manifestations confined to the myocardium. N Engl J Med (1991) 2.27
FAS-induced apoptosis is mediated via a ceramide-initiated RAS signaling pathway. Immunity (1995) 2.19
Total knee arthroplasty in morbidly obese patients. J Bone Joint Surg Am (1998) 2.16
Nucleotide sequence and expression of an operon in Escherichia coli coding for formate hydrogenlyase components. Mol Microbiol (1990) 2.16
Cloning and characterization of a putative human serine/threonine protein kinase transcriptionally modified during anisotonic and isotonic alterations of cell volume. Proc Natl Acad Sci U S A (1997) 2.14
Mutations in GJB6 cause nonsyndromic autosomal dominant deafness at DFNA3 locus. Nat Genet (1999) 2.05
In situ detection of enteroviral genomes in myocardial cells by nucleic acid hybridization: an approach to the diagnosis of viral heart disease. Proc Natl Acad Sci U S A (1987) 2.05
Mitomycin C in combination with capecitabine or biweekly high-dose gemcitabine in patients with advanced biliary tract cancer: a randomised phase II trial. Ann Oncol (2004) 1.95
Cloning and characterization of two human polyspecific organic cation transporters. DNA Cell Biol (1997) 1.91
The product of the hypB gene, which is required for nickel incorporation into hydrogenases, is a novel guanine nucleotide-binding protein. J Bacteriol (1993) 1.90
An almost-intact human endogenous retrovirus K on human chromosome 7. Nat Genet (1999) 1.87
High prevalence of cardiac parvovirus B19 infection in patients with isolated left ventricular diastolic dysfunction. Circulation (2005) 1.84
CD95/CD95 ligand interactions on epithelial cells in host defense to Pseudomonas aeruginosa. Science (2000) 1.77
Synthesis of a muscarinic receptor antagonist via a diastereoselective Michael reaction, selective deoxyfluorination and aromatic metal-halogen exchange reaction. J Org Chem (2001) 1.75
Plant cyclins: a unified nomenclature for plant A-, B- and D-type cyclins based on sequence organization. Plant Mol Biol (1996) 1.73
Enterovirus infection in human pancreatic islet cells, islet tropism in vivo and receptor involvement in cultured islet beta cells. Diabetologia (2004) 1.71
Extracellular K+ and intracellular pH allosterically regulate renal Kir1.1 channels. J Biol Chem (1996) 1.68
Identification of the coding region for a second Epstein-Barr virus nuclear antigen (EBNA 2) by transfection of cloned DNA fragments. EMBO J (1985) 1.65
CUX1: target of Akt signalling and mediator of resistance to apoptosis in pancreatic cancer. Gut (2010) 1.63
Human endogenous retroviral element K10 (HERV-K10) encodes a full-length gag homologous 73-kDa protein and a functional protease. AIDS Res Hum Retroviruses (1993) 1.63
Biweekly high-dose gemcitabine alone or in combination with capecitabine in patients with metastatic pancreatic adenocarcinoma: a randomized phase II trial. Ann Oncol (2003) 1.62
Repulsively bound atom pairs in an optical lattice. Nature (2006) 1.62
Function and structure of heterodimeric amino acid transporters. Am J Physiol Cell Physiol (2001) 1.60
Noninvasive quantification of left-to-right shunt in pediatric patients: phase-contrast cine magnetic resonance imaging compared with invasive oximetry. Circulation (2001) 1.60
Ethylene induces epidermal cell death at the site of adventitious root emergence in rice. Plant Physiol (2000) 1.58
Endogenous retroviruses and cancer. Cell Mol Life Sci (2008) 1.55
Tropism of human cytomegalovirus for endothelial cells is determined by a post-entry step dependent on efficient translocation to the nucleus. J Gen Virol (2000) 1.55
Novel NADPH-binding domain revealed by the crystal structure of aldose reductase. Nature (1992) 1.54
CD66-mediated phagocytosis of Opa52 Neisseria gonorrhoeae requires a Src-like tyrosine kinase- and Rac1-dependent signalling pathway. EMBO J (1998) 1.53
Coxsackie B3 virus can replicate in cultured human foetal heart cells and is inhibited by interferon. J Mol Cell Cardiol (1985) 1.52
A RET double mutation in the germline of a kindred with FMTC. Exp Clin Endocrinol Diabetes (2000) 1.51
Cell volume in the regulation of hepatic function: a mechanism for metabolic control. Biochim Biophys Acta (1991) 1.51
Fas- or ceramide-induced apoptosis is mediated by a Rac1-regulated activation of Jun N-terminal kinase/p38 kinases and GADD153. J Biol Chem (1997) 1.51
The astroglial ASCT2 amino acid transporter as a mediator of glutamine efflux. J Neurochem (1999) 1.50
Programmed cell death protein 4 suppresses CDK1/cdc2 via induction of p21(Waf1/Cip1). Am J Physiol Cell Physiol (2004) 1.49
Myosin light chain-2 luciferase transgenic mice reveal distinct regulatory programs for cardiac and skeletal muscle-specific expression of a single contractile protein gene. J Biol Chem (1992) 1.49
Irinotecan plus raltitrexed vs raltitrexed alone in patients with gemcitabine-pretreated advanced pancreatic adenocarcinoma. Br J Cancer (2003) 1.48
Acidic sphingomyelinase mediates entry of N. gonorrhoeae into nonphagocytic cells. Cell (1997) 1.47
Role of N-linked glycosylation in rat renal Na/Pi-cotransport. J Biol Chem (1994) 1.46
Modulation of Neisseria porin (PorB) by cytosolic ATP/GTP of target cells: parallels between pathogen accommodation and mitochondrial endosymbiosis. Cell (1996) 1.44
Synaptic vesicles: selective depletion in crayfish excitatory and inhibitory axons. Science (1972) 1.44
Second-line treatment of advanced gastric cancer with oxaliplatin plus raltitrexed. Onkologie (2003) 1.41
Blockade of HERG channels expressed in Xenopus oocytes by the histamine receptor antagonists terfenadine and astemizole. FEBS Lett (1996) 1.40
Human endogenous retrovirus protein cORF supports cell transformation and associates with the promyelocytic leukemia zinc finger protein. Oncogene (2000) 1.40
[Isolated myocardial noncompaction in childhood-case report and review of the literature]. Z Kardiol (2003) 1.40
Cellular hydration state: an important determinant of protein catabolism in health and disease. Lancet (1993) 1.38
Role of KCNE1-dependent K+ fluxes in mouse proximal tubule. J Am Soc Nephrol (2001) 1.38
The inhibitory effect of the antipsychotic drug haloperidol on HERG potassium channels expressed in Xenopus oocytes. Br J Pharmacol (1997) 1.38
Two consecutive phase II studies of 5-fluorouracil/leucovorin/mitomycin C and of gemcitabine in patients with advanced biliary cancer. Oncology (1999) 1.38
Evidence for a bicarbonate leak in the proximal tubule of the rat kidney. Pflugers Arch (1980) 1.36
Efficient detection and immunomagnetic sorting of specific T cells using multimers of MHC class I and peptide with reduced CD8 binding. Nat Med (2000) 1.33
Direct myocardial injury by enterovirus: a central role in the evolution of murine myocarditis. Clin Immunol Immunopathol (1993) 1.32
Cardioselective infection with coxsackievirus B3 requires intact type I interferon signaling: implications for mortality and early viral replication. Circulation (2001) 1.31
Transport characteristics of a murine renal Na/Pi-cotransporter. Pflugers Arch (1995) 1.30
Electrophysiological characterization of the flounder type II Na+/Pi cotransporter (NaPi-5) expressed in Xenopus laevis oocytes. J Membr Biol (1997) 1.30
The tyrosine kinase p56lck mediates activation of swelling-induced chloride channels in lymphocytes. J Cell Biol (1998) 1.30
The perifollicular and marginal zones of the human splenic white pulp : do fibroblasts guide lymphocyte immigration? Am J Pathol (2001) 1.30
Ca2+-activated K channel of the BK-type in the inner mitochondrial membrane of a human glioma cell line. Biochem Biophys Res Commun (1999) 1.29
Genomic organization of the human endogenous retrovirus HERV-K(HML-2.HOM) (ERVK6) on chromosome 7. Genomics (2001) 1.28
Maturation of the large subunit (HYCE) of Escherichia coli hydrogenase 3 requires nickel incorporation followed by C-terminal processing at Arg537. Eur J Biochem (1994) 1.27
Cell swelling inhibits proteolysis in perfused rat liver. Biochem J (1990) 1.27
Characterization of a 100-kilodalton binding protein for the six serotypes of coxsackie B viruses. J Virol (1995) 1.26
Human papillomavirus type 16-associated primary squamous cell carcinoma of the rectum. Gastroenterology (2001) 1.26
Interactions between glutamine metabolism and cell-volume regulation in perfused rat liver. Eur J Biochem (1990) 1.25
Coronary vasospasm as the underlying cause for chest pain in patients with PVB19 myocarditis. Heart (2008) 1.24
Inhibition of IKs in guinea pig cardiac myocytes and guinea pig IsK channels by the chromanol 293B. Pflugers Arch (1996) 1.24
GLP-1 stimulates secretion of macromolecules from airways and relaxes pulmonary artery. Am J Physiol (1993) 1.23
Tyrosine phosphorylation-dependent suppression of a voltage-gated K+ channel in T lymphocytes upon Fas stimulation. J Biol Chem (1996) 1.23
Interference of H2O2 with stimulus-secretion coupling in mouse pancreatic beta-cells. J Physiol (1999) 1.23
Tyrosine kinase-dependent activation of a chloride channel in CD95-induced apoptosis in T lymphocytes. Proc Natl Acad Sci U S A (1998) 1.22
Pathogenesis of murine enterovirus myocarditis: virus dissemination and immune cell targets. J Virol (1996) 1.22
Human neurons express the polyspecific cation transporter hOCT2, which translocates monoamine neurotransmitters, amantadine, and memantine. Mol Pharmacol (1998) 1.21
L-selectin activates the Ras pathway via the tyrosine kinase p56lck. Proc Natl Acad Sci U S A (1996) 1.20
Deranged transcriptional regulation of cell-volume-sensitive kinase hSGK in diabetic nephropathy. Proc Natl Acad Sci U S A (2000) 1.20
HERV-K(OLD): ancestor sequences of the human endogenous retrovirus family HERV-K(HML-2). J Virol (2001) 1.20
The heterodimeric amino acid transporter 4F2hc/y+LAT2 mediates arginine efflux in exchange with glutamine. Biochem J (2000) 1.20
Activation of CDK-activating kinase is dependent on interaction with H-type cyclins in plants. Plant J (2000) 1.19
Mapping of the RD phenotype of the Nancy strain of coxsackievirus B3. Virus Res (1992) 1.19
Regulation of cell function by the cellular hydration state. Am J Physiol (1994) 1.19
Obligatory amino acid exchange via systems bo,+-like and y+L-like. A tertiary active transport mechanism for renal reabsorption of cystine and dibasic amino acids. J Biol Chem (1996) 1.19
Neutral amino acid transporter ASCT2 displays substrate-induced Na+ exchange and a substrate-gated anion conductance. Biochem J (2000) 1.19
Electrophysiology of sodium-coupled transport in proximal renal tubules. Am J Physiol (1986) 1.18
Novel ribosomal genes from maize are differentially expressed in the zygotic and somatic cell cycles. Mol Gen Genet (1999) 1.17
A search for the presence of the enteroviral capsid protein VP1 in pancreases of patients with type 1 (insulin-dependent) diabetes and pancreases and hearts of infants who died of coxsackieviral myocarditis. Diabetologia (1990) 1.17